Suppression of QRFP 43 in the hypothalamic ventromedial nucleus of Long-Evans rats fed a high-fat diet

Biochemical and Biophysical Research Communications

Volumn 383, Issue 1, 2009, Pages 78-82

  Beck, Bernard ^a,b   Richy, Sébastien ^b  

^a INSERM   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

Author keywords

Adiposity; Food intake; Insulin; Lateral hypothalamus; Leptin

Indexed keywords

BRAIN PROTEIN; INSULIN; LEPTIN; PYROGLUTAMYLATED ARGININE PHENYLALANINE AMIDE PROTEIN 43; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; FOOD INTAKE; HORMONE BLOOD LEVEL; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; LATERAL HYPOTHALAMUS; LIPID DIET; LONG EVANS RAT; LOW FAT DIET; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT;

MUS; RATTUS;

EID: 67349258545     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.03.132     Document Type: Article

References (35)

1. Beck B., Pourié C., and Guéant J. Neuropeptides B, S and W, obestatin/ghrelin-associated peptide, and others: really new feeding regulatory peptides?. CNS Agents Med. Chem. 8 (2008) 29-36
2. Chartrel N., Dujardin C., Anouar Y., Leprince J., Decker A., Clerens S., DoRego J.C., Vandesande F., LlorensCortes C., Costentin J., Beauvillain J.C., and Vaudry H. Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. Proc. Natl. Acad. Sci. USA 100 (2003) 15247-15252
3. Fukusumi S., Yoshida H., Fujii R., Maruyama M., Komatsu H., Habata Y., Shintani Y., Hinuma S., and Fujino M. A new peptidic ligand and its receptor regulating adrenal function in rats. J. Biol. Chem. 278 (2003) 46387-46395
4. Jiang Y., Luo L., Gustafson E., Yadav D., Laverty M., Murgolo N., Vassileva G., Zeng M., Laz T., Behan J., Qiu P., Wang L., Wang S., Bayne M., Greene J., Monsma F.J., and Zhang F. Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155. J. Biol. Chem. 278 (2003) 27652
5. Takayasu S., Sakurai T., Iwasaki S., Teranishi H., Yamanaka A., Williams S.C., Iguchi H., Kawasawa Y.I., Ikeda Y., Sakakibara L., Ohno K., Ioka R.X., Murakami S., Dohmae N., Xie J., Suda T., Motoike T., Ohuchi T., Yanagisawa M., and Sakai J. A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice. Proc. Natl. Acad. Sci. USA 103 (2006) 7438-7443
6. Kampe J., Wiedmer P., Pfluger P.T., Castaneda T.R., Burget L., Mondala H., Kerr J., Liaw C., Oldfield B.J., Tschop M.H., and Bagnol D. Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat. Brain Res. 1119 (2006) 133-149
7. Bruzzone F., Lectez B., Tollemer H., Leprince J., Dujardin C., Rachidi W., Chatenet D., Baroncini M., Beauvillain J., Vallarino M., Vaudry H., and Chartrel N. Anatomical distribution and biochemical characterization of the novel RFamide peptide 26RFa in the human hypothalamus and spinal cord. J. Neurochem. 99 (2006) 616-627
8. Morton G.J., Cummings D.E., Baskin D.G., Barsh G.S., and Schwartz M.W. Central nervous system control of food intake and body weight. Nature 443 (2006) 289-295
9. do Rego J., Leprince J., Chartrel N., Vaudry H., and Costentin J. Behavioral effects of 26RFamide and related peptides. Peptides 27 (2006) 2715-2721
10. Beck B. Neuropeptide Y in normal eating and in genetic and dietary-induced obesity. Philos. Trans. R. Soc. B Biol. Sci. 361 (2006) 1159-1185
11. Moriya R., Sano H., Umeda T., Ito M., Takahashi Y., Matsuda M., Ishihara A., Kanatani A., and Iwaasa H. RFamide peptide QRFP43 causes obesity with hyperphagia and reduced thermogenesis in mice. Endocrinology 147 (2006) 2916-2922
12. Beck B., Jhanwar-Uniyal M., Burlet A., Chapleur-Chateau M., Leibowitz S.F., and Burlet C. Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status. Brain Res. 528 (1990) 245-249
13. Beck B., Richy S., and StrickerKrongrad A. Ghrelin and body weight regulation in the obese Zucker rat in relation to feeding state and dark/light cycle. Exp. Biol. Med. 228 (2003) 1124-1131
14. Patel S.R., Murphy K.G., Thompson E.L., Patterson M., Curtis A.E., Ghatei M.A., and Bloom S.R. Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats. Endocrinology 149 (2008) 4747-4754
15. Wetherill L., Schuckit M.A., Hesselbrock V., Xuei X.L., Liang T.B., Dick D.M., Kramer J., Nurnberger J.I., Tischfield J.A., Porjesz B., Edenberg H.J., and Foroud T. Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. Alcohol Clin. Exp. Res. 32 (2008) 2031-2040
16. Mercer J.G., Hoggard N., Williams L.M., Lawrence C.B., Hannah L.T., and Trayhurn P. Localization of leptin receptor mRNA and the long form splice variant (ob-rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett. 387 (1996) 113-116
17. Schwartz M.W., Seeley R.J., Campfield L.A., Burn P., and Baskin D.G. Identification of targets of leptin action in rat hypothalamus. J. Clin. Invest. 98 (1996) 1101-1106
18. Fei H., Okano H.J., Li C., Lee G.H., Zhao C., Darnell R., and Friedman J.M. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc. Natl. Acad. Sci. USA 94 (1997) 7001-7005
19. Dhillon H., Zigman J.M., Ye C.P., Lee C.E., McGovern R.A., Tang V.S., Kenny C.D., Christiansen L.M., White R.D., Edelstein E.A., Coppari R., Balthasar N., Cowley M.A., Chua S., Elmquist J.K., and Lowelll B.B. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 49 (2006) 191-203
20. Bingham N.C., Anderson K.K., Reuter A.L., Stallings N.R., and Parker K.L. Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome. Endocrinology 149 (2008) 2138-2148
21. Ahren B., Mansson S., Gingerich R.L., and Havel P.J. Regulation of plasma leptin in mice. Influence of age, high-fat diet, and fasting. Am. J. Physiol. 42 (1997) R113-R120
22. Stricker-Krongrad A., Cumin F., Burlet C., and Beck B. Hypothalamic neuropeptide Y and plasma leptin after long-term high-fat feeding in the rat. Neurosci. Lett. 254 (1998) 157-160
23. Cooling J., Barth J., and Blundell J. The high-fat phenotype: Is leptin involved in the adaptive response to a high fat (high energy) diet?. Int. J. Obes. 22 (1998) 1132-1135
24. Beck B., and Richy S. Differential long-term dietary regulation of adipokines, ghrelin, or corticosterone: impact on adiposity. J. Endocrinol. 196 (2008) 171-179
25. Palkovits M. Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res. 59 (1973) 449-450
26. Beck B., Stricker-Krongrad A., Burlet A., Max J.P., Musse N., Nicolas J.P., and Burlet C. Macronutrient type independently of energy intake modulates hypothalamic neuropeptide Y in Long-Evans rats. Brain Res. Bull. 34 (1994) 85-91
27. Oscai L.B., Brown M.M., and Miller W.C. Effect of dietary fat on food intake, growth and body composition in rats. Growth 48 (1984) 415-424
28. Levin B.E., Triscari J., and Sullivan A.C. Metabolic features of diet-induced obesity without hyperphagia in young rats. Am. J. Physiol. 20 (1986) R433-R440
29. Zhang J., Matheny M.K., Tumer N., Mitchell M.K., and Scarpace P.J. Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent. Am. J. Physiol. 292 (2007) R868-R874
30. Considine R.V., Sinha M.K., Heiman M.L., Kriauciunas A., Stephens T.W., Nyce M.R., Ohannesian J.P., Marco C.C., Mckee L.J., Bauer T.L., and Caro J.F. Serum immunoreactive leptin concentrations in normal-weight and obese humans. N. Engl. J. Med. 334 (1996) 292-295
31. Beck B. The arcuate nucleus: its special place in the central networks that regulate feeding behavior. In: Zempleni J., and Dakshinamurti K. (Eds). Nutrient and Cell Signalling (2005), Dekker, New-York 665-699
32. Komori T., Morikawa Y., Nanjo K., and Senba E. Induction of brain-derived neurotrophic factor by leptin in the ventromedial hypothalamus. Neuroscience 139 (2006) 1107-1115
33. Wang C.F., Bomberg E., Levine A., Billington C., and Kotz C.M. Brain-derived neurotrophic factor in the ventromedial nucleus of the hypothalamus reduces energy intake. Am. J. Physiol. 293 (2007) R1037-R1045
34. Nishiyama M., Makino S., Asaba K., and Hashimoto K. Leptin effects on the expression of type-2 CRH receptor mRNA in the ventromedial hypothalamus in the rat. J. Neuroendocrinol. 11 (1999) 307-314
35. King B.M. The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol. Behav. 87 (2006) 221-244