-
1
-
-
70350104716
-
The optogenetic catechism
-
Miesenböck, G. The optogenetic catechism. Science 326, 395-399 (2009).
-
(2009)
Science
, vol.326
, pp. 395-399
-
-
Miesenböck, G.1
-
2
-
-
79959873914
-
The development and application of optogenetics
-
Fenno, L., Yizhar, O. & Deisseroth, K. The development and application of optogenetics. Annu. Rev. Neurosci. 34, 389-412 (2011).
-
(2011)
Annu. Rev. Neurosci.
, vol.34
, pp. 389-412
-
-
Fenno, L.1
Yizhar, O.2
Deisseroth, K.3
-
3
-
-
0028997924
-
Conversion of bacteriorhodopsin into a chloride ion pump
-
Sasaki, J. et al. Conversion of bacteriorhodopsin into a chloride ion pump. Science 269, 73-75 (1995).
-
(1995)
Science
, vol.269
, pp. 73-75
-
-
Sasaki, J.1
-
4
-
-
0345133280
-
Channelrhodopsin-2, a directly light-gated cation-selective membrane channel
-
Nagel, G. et al. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc. Natl. Acad. Sci. USA 100, 13940-13945 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13940-13945
-
-
Nagel, G.1
-
5
-
-
84455178930
-
The microbial opsin family of optogenetic tools
-
Zhang, F. et al. The microbial opsin family of optogenetic tools. Cell 147, 1446-1457 (2011).
-
(2011)
Cell
, vol.147
, pp. 1446-1457
-
-
Zhang, F.1
-
6
-
-
26444621497
-
Millisecond-Timescale genetically targeted optical control of neural activity
-
Boyden, E.S., Zhang, F., Bamberg, E., Nagel, G. & Deisseroth, K. Millisecond-Timescale, genetically targeted optical control of neural activity. Nat. Neurosci. 8, 1263-1268 (2005).
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1263-1268
-
-
Boyden, E.S.1
Zhang, F.2
Bamberg, E.3
Nagel, G.4
Deisseroth, K.5
-
7
-
-
65549086510
-
Temporally precise in vivo control of intracellular signalling
-
Airan, R.D., Thompson, K.R., Fenno, L.E., Bernstein, H. & Deisseroth, K. Temporally precise in vivo control of intracellular signalling. Nature 458, 1025-1029 (2009).
-
(2009)
Nature
, vol.458
, pp. 1025-1029
-
-
Airan, R.D.1
Thompson, K.R.2
Fenno, L.E.3
Bernstein, H.4
Deisseroth, K.5
-
8
-
-
77957281947
-
Substitution of 5-HT1A receptor signaling by a light-Activated G protein-coupled receptor
-
Oh, E., Maejima, T., Liu, C., Deneris, E. & Herlitze, S. Substitution of 5-HT1A receptor signaling by a light-Activated G protein-coupled receptor. J. Biol. Chem. 285, 30825-30836 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 30825-30836
-
-
Oh, E.1
Maejima, T.2
Liu, C.3
Deneris, E.4
Herlitze, S.5
-
9
-
-
80052282876
-
Cell type-specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function
-
Zhao, S. et al. Cell type-specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function. Nat. Methods 8, 745-752 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 745-752
-
-
Zhao, S.1
-
10
-
-
84886950236
-
A disinhibitory circuit mediates motor integration in the somatosensory cortex
-
Lee, S., Kruglikov, I., Huang, Z.J., Fishell, G. & Rudy, B. A disinhibitory circuit mediates motor integration in the somatosensory cortex. Nat. Neurosci. 16, 1662-1670 (2013).
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1662-1670
-
-
Lee, S.1
Kruglikov, I.2
Huang, Z.J.3
Fishell, G.4
Rudy, B.5
-
11
-
-
84895558645
-
Optogenetic control of Drosophila using a red-shifted channelrhodopsin reveals experience-dependent influences on courtship
-
Inagaki, H.K. et al. Optogenetic control of Drosophila using a red-shifted channelrhodopsin reveals experience-dependent influences on courtship. Nat. Methods 11, 325-332 (2014).
-
(2014)
Nat. Methods
, vol.11
, pp. 325-332
-
-
Inagaki, H.K.1
-
12
-
-
84879135819
-
ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains
-
Kolisnyk, B. et al. ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains. J. Neurosci. 33, 10427-10438 (2013).
-
(2013)
J. Neurosci.
, vol.33
, pp. 10427-10438
-
-
Kolisnyk, B.1
-
13
-
-
84873654803
-
Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice
-
Abbott, S.B. et al. Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice. J. Neurosci. 33, 3164-3177 (2013).
-
(2013)
J. Neurosci.
, vol.33
, pp. 3164-3177
-
-
Abbott, S.B.1
-
14
-
-
78149368433
-
Optogenetic control of cardiac function
-
Arrenberg, A.B., Stainier, D.Y., Baier, H. & Huisken, J. Optogenetic control of cardiac function. Science 330, 971-974 (2010).
-
(2010)
Science
, vol.330
, pp. 971-974
-
-
Arrenberg, A.B.1
Stainier, D.Y.2
Baier, H.3
Huisken, J.4
-
15
-
-
78049321336
-
Optogenetic control of heart muscle in vitro and in vivo
-
Bruegmann, T. et al. Optogenetic control of heart muscle in vitro and in vivo. Nat. Methods 7, 897-900 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 897-900
-
-
Bruegmann, T.1
-
16
-
-
79951830489
-
Tracking stem cell differentiation in the setting of automated optogenetic stimulation
-
Stroh, A. et al. Tracking stem cell differentiation in the setting of automated optogenetic stimulation. Stem Cells 29, 78-88 (2011).
-
(2011)
Stem Cells
, vol.29
, pp. 78-88
-
-
Stroh, A.1
-
17
-
-
84861389671
-
LOV to BLUF: Flavoprotein contributions to the optogenetic toolkit
-
Christie, J.M., Gawthorne, J., Young, G., Fraser, N.J. & Roe, A.J. LOV to BLUF: Flavoprotein contributions to the optogenetic toolkit. Mol. Plant 5, 533-544 (2012).
-
(2012)
Mol. Plant
, vol.5
, pp. 533-544
-
-
Christie, J.M.1
Gawthorne, J.2
Young, G.3
Fraser, N.J.4
Roe, A.J.5
-
18
-
-
79955584998
-
The cryptochromes: Blue light photoreceptors in plants and animals
-
Chaves, I. et al. The cryptochromes: Blue light photoreceptors in plants and animals. Annu. Rev. Plant Biol. 62, 335-364 (2011).
-
(2011)
Annu. Rev. Plant Biol.
, vol.62
, pp. 335-364
-
-
Chaves, I.1
-
19
-
-
70350070364
-
Spatiotemporal control of cell signalling using a light-switchable protein interaction
-
Levskaya, A., Weiner, O.D., Lim, W.A. & Voigt, C.A. Spatiotemporal control of cell signalling using a light-switchable protein interaction. Nature 461, 997-1001 (2009).
-
(2009)
Nature
, vol.461
, pp. 997-1001
-
-
Levskaya, A.1
Weiner, O.D.2
Lim, W.A.3
Voigt, C.A.4
-
20
-
-
0036789439
-
A light-switchable gene promoter system
-
Shimizu-Sato, S., Huq, E., Tepperman, J.M. & Quail, P.H. A light-switchable gene promoter system. Nat. Biotechnol. 20, 1041-1044 (2002).
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1041-1044
-
-
Shimizu-Sato, S.1
Huq, E.2
Tepperman, J.M.3
Quail, P.H.4
-
21
-
-
49449118042
-
Light-Activated DNA binding in a designed allosteric protein
-
Strickland, D., Moffat, K. & Sosnick, T.R. Light-Activated DNA binding in a designed allosteric protein. Proc. Natl. Acad. Sci. USA 105, 10709-10714 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 10709-10714
-
-
Strickland, D.1
Moffat, K.2
Sosnick, T.R.3
-
22
-
-
70349967637
-
Induction of protein-protein interactions in live cells using light
-
Yazawa, M., Sadaghiani, A.M., Hsueh, B. & Dolmetsch, R.E. Induction of protein-protein interactions in live cells using light. Nat. Biotechnol. 27, 941-945 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 941-945
-
-
Yazawa, M.1
Sadaghiani, A.M.2
Hsueh, B.3
Dolmetsch, R.E.4
-
23
-
-
78649714869
-
Rapid blue-light-mediated induction of protein interactions in living cells
-
Kennedy, M.J. et al. Rapid blue-light-mediated induction of protein interactions in living cells. Nat. Methods 7, 973-975 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 973-975
-
-
Kennedy, M.J.1
-
24
-
-
84862776564
-
Spatiotemporal control of gene expression by a light-switchable transgene system
-
Wang, X., Chen, X. & Yang, Y. Spatiotemporal control of gene expression by a light-switchable transgene system. Nat. Methods 9, 266-269 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 266-269
-
-
Wang, X.1
Chen, X.2
Yang, Y.3
-
25
-
-
84882976110
-
Optical control of mammalian endogenous transcription and epigenetic states
-
Konermann, S. et al. Optical control of mammalian endogenous transcription and epigenetic states. Nature 500, 472-476 (2013).
-
(2013)
Nature
, vol.500
, pp. 472-476
-
-
Konermann, S.1
-
26
-
-
84889261444
-
Oscillatory control of factors determining multipotency and fate in mouse neural progenitors
-
The accurate control of gene exression with light demonstrates the imortance of oscillatory versus sustained exression in cell fate
-
Imayoshi, I. et al. Oscillatory control of factors determining multipotency and fate in mouse neural progenitors. Science 342, 1203-1208 (2013). The accurate control of gene expression with light demonstrates the importance of oscillatory versus sustained expression in cell fate.
-
(2013)
Science
, vol.342
, pp. 1203-1208
-
-
Imayoshi, I.1
-
27
-
-
80053347082
-
Light-based feedback for controlling intracellular signaling dynamics
-
Toettcher, J.E., Gong, D., Lim, W.A. & Weiner, O.D. Light-based feedback for controlling intracellular signaling dynamics. Nat. Methods 8, 837-839 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 837-839
-
-
Toettcher, J.E.1
Gong, D.2
Lim, W.A.3
Weiner, O.D.4
-
28
-
-
84878586112
-
A light-Triggered protein secretion system
-
Chen, D., Gibson, E.S. & Kennedy, M.J. A light-Triggered protein secretion system. J. Cell Biol. 201, 631-640 (2013).
-
(2013)
J. Cell Biol.
, vol.201
, pp. 631-640
-
-
Chen, D.1
Gibson, E.S.2
Kennedy, M.J.3
-
29
-
-
54249105941
-
Surface sites for engineering allosteric control in proteins
-
Lee, J. et al. Surface sites for engineering allosteric control in proteins. Science 322, 438-442 (2008).
-
(2008)
Science
, vol.322
, pp. 438-442
-
-
Lee, J.1
-
30
-
-
78651396502
-
Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa
-
Stierl, M. et al. Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. J. Biol. Chem. 286, 1181-1188 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 1181-1188
-
-
Stierl, M.1
-
31
-
-
84885579044
-
A LOV-domain-mediated blue-light-Activated adenylate (adenylyl) cyclase from the cyanobacterium Microcoleus chthonoplastes PCC 7420
-
Raffelberg, S. et al. A LOV-domain-mediated blue-light-Activated adenylate (adenylyl) cyclase from the cyanobacterium Microcoleus chthonoplastes PCC 7420. Biochem. J. 455, 359-365 (2013).
-
(2013)
Biochem. J.
, vol.455
, pp. 359-365
-
-
Raffelberg, S.1
-
32
-
-
51349089700
-
Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway
-
Leung, D.W., Otomo, C., Chory, J. & Rosen, M.K. Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway. Proc. Natl. Acad. Sci. USA 105, 12797-12802 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 12797-12802
-
-
Leung, D.W.1
Otomo, C.2
Chory, J.3
Rosen, M.K.4
-
33
-
-
84876461247
-
LOV2 domain-based optogenetic tool to control protein degradation and cellular function
-
Renicke, C., Schuster, D., Usherenko, S., Essen, L.O. & Taxis, C.A. LOV2 domain-based optogenetic tool to control protein degradation and cellular function. Chem. Biol. 20, 619-626 (2013).
-
(2013)
Chem. Biol.
, vol.20
, pp. 619-626
-
-
Renicke, C.1
Schuster, D.2
Usherenko, S.3
Essen, L.O.4
Taxis, C.A.5
-
34
-
-
84900400870
-
General method for regulating protein stability with light
-
Bonger, K.M., Rakhit, R., Payumo, A.Y., Chen, J.K. & Wandless, T.J. General method for regulating protein stability with light. ACS Chem. Biol. 9, 111-115 (2014).
-
(2014)
ACS Chem. Biol.
, vol.9
, pp. 111-115
-
-
Bonger, K.M.1
Rakhit, R.2
Payumo, A.Y.3
Chen, J.K.4
Wandless, T.J.5
-
35
-
-
84865101790
-
Light-controlled tools
-
A recent review dealing with chemical strategies of irreversible and reversible photoactivation for biological applications.
-
Brieke, C., Rohrbach, F., Gottschalk, A., Mayer, G. & Heckel, A. Light-controlled tools. Angew. Chem. Int. Edn Engl. 51, 8446-8476 (2012). A recent review dealing with chemical strategies of irreversible and reversible photoactivation for biological applications.
-
(2012)
Angew. Chem. Int. Edn Engl.
, vol.51
, pp. 8446-8476
-
-
Brieke, C.1
Rohrbach, F.2
Gottschalk, A.3
Mayer, G.4
Heckel, A.5
-
36
-
-
34547638628
-
Caged compounds: Photorelease technology for control of cellular chemistry and physiology
-
Ellis-Davies, G.C. Caged compounds: Photorelease technology for control of cellular chemistry and physiology. Nat. Methods 4, 619-628 (2007).
-
(2007)
Nat. Methods
, vol.4
, pp. 619-628
-
-
Ellis-Davies, G.C.1
-
37
-
-
0036909269
-
Spatially discrete, light-driven protein expression
-
Lin, W., Albanese, C., Pestell, R.G. & Lawrence, D.S. Spatially discrete, light-driven protein expression. Chem. Biol. 9, 1347-1353 (2002).
-
(2002)
Chem. Biol.
, vol.9
, pp. 1347-1353
-
-
Lin, W.1
Albanese, C.2
Pestell, R.G.3
Lawrence, D.S.4
-
38
-
-
4544259346
-
Light-Activated transcription and repression by using photocaged SERMs
-
Shi, Y. & Koh, J.T. Light-Activated transcription and repression by using photocaged SERMs. ChemBioChem 5, 788-796 (2004).
-
(2004)
ChemBioChem
, vol.5
, pp. 788-796
-
-
Shi, Y.1
Koh, J.T.2
-
39
-
-
67649625533
-
Doxycycline-dependent photoactivated gene expression in eukaryotic systems
-
Cambridge, S.B. et al. Doxycycline-dependent photoactivated gene expression in eukaryotic systems. Nat. Methods 6, 527-531 (2009).
-
(2009)
Nat. Methods
, vol.6
, pp. 527-531
-
-
Cambridge, S.B.1
-
40
-
-
25444480818
-
Light activated recombination
-
Link, K.H., Shi, Y. & Koh, J.T. Light activated recombination. J. Am. Chem. Soc. 127, 13088-13089 (2005).
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 13088-13089
-
-
Link, K.H.1
Shi, Y.2
Koh, J.T.3
-
41
-
-
77949823382
-
Photocontrol of protein activity in cultured cells and zebrafish with one-And two-photon illumination
-
Sinha, D.K. et al. Photocontrol of protein activity in cultured cells and zebrafish with one-And two-photon illumination. ChemBioChem 11, 653-663 (2010).
-
(2010)
Chem Bio Chem
, vol.11
, pp. 653-663
-
-
Sinha, D.K.1
-
42
-
-
77953623529
-
Photoactivation of the CreER T2 recombinase for conditional site-specific recombination with high spatiotemporal resolution
-
Sinha, D.K. et al. Photoactivation of the CreER T2 recombinase for conditional site-specific recombination with high spatiotemporal resolution. Zebrafish 7, 199-204 (2010).
-
(2010)
Zebrafish
, vol.7
, pp. 199-204
-
-
Sinha, D.K.1
-
43
-
-
78650992316
-
A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity
-
Umeda, N., Ueno, T., Pohlmeyer, C., Nagano, T. & Inoue, T. A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity. J. Am. Chem. Soc. 133, 12-14 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 12-14
-
-
Umeda, N.1
Ueno, T.2
Pohlmeyer, C.3
Nagano, T.4
Inoue, T.5
-
44
-
-
79851502862
-
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP
-
Karginov, A.V. et al. Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. J. Am. Chem. Soc. 133, 420-423 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 420-423
-
-
Karginov, A.V.1
-
45
-
-
77950279568
-
Genetically encoded photocontrol of protein localization in mammalian cells
-
Gautier, A. et al. Genetically encoded photocontrol of protein localization in mammalian cells. J. Am. Chem. Soc. 132, 4086-4088 (2010).
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 4086-4088
-
-
Gautier, A.1
-
46
-
-
79951830445
-
Light-Activated kinases enable temporal dissection of signaling networks in living cells
-
Gautier, A., Deiters, A. & Chin, J.W. Light-Activated kinases enable temporal dissection of signaling networks in living cells. J. Am. Chem. Soc. 133, 2124-2127 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 2124-2127
-
-
Gautier, A.1
Deiters, A.2
Chin, J.W.3
-
47
-
-
84864276237
-
Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine
-
Arbely, E., Torres-Kolbus, J., Deiters, A. & Chin, J.W. Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine. J. Am. Chem. Soc. 134, 11912-11915 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 11912-11915
-
-
Arbely, E.1
Torres-Kolbus, J.2
Deiters, A.3
Chin, J.W.4
-
48
-
-
84894148049
-
Genetic encoding of photocaged cysteine allows photoactivation of TEV protease in live mammalian cells
-
Nguyen, D.P. et al. Genetic encoding of photocaged cysteine allows photoactivation of TEV protease in live mammalian cells. J. Am. Chem. Soc. 136, 2240-2243 (2014).
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 2240-2243
-
-
Nguyen, D.P.1
-
49
-
-
84884192015
-
Genetically encoded light-Activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells
-
Hemphill, J., Chou, C., Chin, J.W. & Deiters, A. Genetically encoded light-Activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells. J. Am. Chem. Soc. 135, 13433-13439 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 13433-13439
-
-
Hemphill, J.1
Chou, C.2
Chin, J.W.3
Deiters, A.4
-
50
-
-
84865327729
-
Expanding the genetic code of Drosophila melanogaster
-
Bianco, A., Townsley, F.M., Greiss, S., Lang, K. & Chin, J.W. Expanding the genetic code of Drosophila melanogaster. Nat. Chem. Biol. 8, 748-750 (2012).
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 748-750
-
-
Bianco, A.1
Townsley, F.M.2
Greiss, S.3
Lang, K.4
Chin, J.W.5
-
51
-
-
12344309164
-
Light-Activated ion channels for remote control of neuronal firing
-
Banghart, M., Borges, K., Isacoff, E., Trauner, D. & Kramer, R.H. Light-Activated ion channels for remote control of neuronal firing. Nat. Neurosci. 7, 1381-1386 (2004).
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 1381-1386
-
-
Banghart, M.1
Borges, K.2
Isacoff, E.3
Trauner, D.4
Kramer, R.H.5
-
52
-
-
41449113929
-
Photochemical control of endogenous ion channels and cellular excitability
-
Fortin, D.L. et al. Photochemical control of endogenous ion channels and cellular excitability. Nat. Methods 5, 331-338 (2008).
-
(2008)
Nat. Methods
, vol.5
, pp. 331-338
-
-
Fortin, D.L.1
-
53
-
-
33645218213
-
Allosteric control of an ionotropic glutamate receptor with an optical switch
-
Volgraf, M. et al. Allosteric control of an ionotropic glutamate receptor with an optical switch. Nat. Chem. Biol. 2, 47-52 (2006).
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 47-52
-
-
Volgraf, M.1
-
54
-
-
34248548818
-
Remote control of neuronal activity with a light-gated glutamate receptor
-
Szobota, S. et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron 54, 535-545 (2007).
-
(2007)
Neuron
, vol.54
, pp. 535-545
-
-
Szobota, S.1
-
55
-
-
77955052419
-
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing
-
Janovjak, H., Szobota, S., Wyart, C., Trauner, D. & Isacoff, E.Y. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nat. Neurosci. 13, 1027-1032 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1027-1032
-
-
Janovjak, H.1
Szobota, S.2
Wyart, C.3
Trauner, D.4
Isacoff, E.Y.5
-
56
-
-
84897024230
-
Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy
-
Reiner, A. & Isacoff, E.Y. Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy. Nat. Chem. Biol. 10, 273-280 (2014).
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 273-280
-
-
Reiner, A.1
Isacoff, E.Y.2
-
57
-
-
78650865624
-
The promise of optogenetics in cell biology: Interrogating molecular circuits in space and time
-
Toettcher, J.E., Voigt, C.A., Weiner, O.D. & Lim, W.A. The promise of optogenetics in cell biology: Interrogating molecular circuits in space and time. Nat. Methods 8, 35-38 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 35-38
-
-
Toettcher, J.E.1
Voigt, C.A.2
Weiner, O.D.3
Lim, W.A.4
-
58
-
-
84890036078
-
Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module
-
Toettcher, J.E., Weiner, O.D. & Lim, W.A. Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module. Cell 155, 1422-1434 (2013).
-
(2013)
Cell
, vol.155
, pp. 1422-1434
-
-
Toettcher, J.E.1
Weiner, O.D.2
Lim, W.A.3
-
59
-
-
75549087930
-
BioNumbers-The database of key numbers in molecular and cell biology
-
Milo, R., Jorgensen, P., Moran, U., Weber, G. & Springer, M. BioNumbers-The database of key numbers in molecular and cell biology. Nucleic Acids Res. 38, D750-D753 (2010).
-
(2010)
Nucleic Acids Res.
, vol.38
-
-
Milo, R.1
Jorgensen, P.2
Moran, U.3
Weber, G.4
Springer, M.5
-
60
-
-
84872237121
-
Photoremovable protecting groups in chemistry and biology: Reaction mechanisms and efficacy
-
Klán, P. et al. Photoremovable protecting groups in chemistry and biology: Reaction mechanisms and efficacy. Chem. Rev. 113, 119-191 (2013).
-
(2013)
Chem. Rev.
, vol.113
, pp. 119-191
-
-
Klán, P.1
-
61
-
-
84857066665
-
Two-photon optogenetics
-
Oron, D., Papagiakoumou, E., Anselmi, F. & Emiliani, V. Two-photon optogenetics. Prog. Brain Res. 196, 119-143 (2012).
-
(2012)
Prog. Brain Res.
, vol.196
, pp. 119-143
-
-
Oron, D.1
Papagiakoumou, E.2
Anselmi, F.3
Emiliani, V.4
-
62
-
-
0032906554
-
Photolysis of caged calcium in femtoliter volumes using two-photon excitation
-
Brown, E.B., Shear, J.B., Adams, S.R., Tsien, R.Y. & Webb, W.W. Photolysis of caged calcium in femtoliter volumes using two-photon excitation. Biophys. J. 76, 489-499 (1999).
-
(1999)
Biophys. J.
, vol.76
, pp. 489-499
-
-
Brown, E.B.1
Shear, J.B.2
Adams, S.R.3
Tsien, R.Y.4
Webb, W.W.5
-
63
-
-
0036182941
-
Two-photon excitation and photolysis by pulsed laser illumination modelled by spatially non-uniform reactions with simultaneous diffusion
-
Kiskin, N.I. & Ogden, D. Two-photon excitation and photolysis by pulsed laser illumination modelled by spatially non-uniform reactions with simultaneous diffusion. Eur. Biophys. J. 30, 571-587 (2002).
-
(2002)
Eur. Biophys. J.
, vol.30
, pp. 571-587
-
-
Kiskin, N.I.1
Ogden, D.2
-
64
-
-
0037471671
-
A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage
-
Zayat, L., Calero, C., Albores, P., Baraldo, L. & Etchenique, R. A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J. Am. Chem. Soc. 125, 882-883 (2003).
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 882-883
-
-
Zayat, L.1
Calero, C.2
Albores, P.3
Baraldo, L.4
Etchenique, R.5
-
65
-
-
84856908802
-
Water-soluble, donor-Acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series: Highly efficient two-photon uncaging of the neurotransmitter gamma-Aminobutyric acid at ? = 800 nm
-
Donato, L. et al. Water-soluble, donor-Acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series: Highly efficient two-photon uncaging of the neurotransmitter gamma-Aminobutyric acid at ? = 800 nm. Angew. Chem. Int. Edn Engl. 51, 1840-1843 (2012).
-
(2012)
Angew. Chem. Int. Edn Engl.
, vol.51
, pp. 1840-1843
-
-
Donato, L.1
-
66
-
-
84871592349
-
O-fluoroazobenzenes as readily synthesized photoswitches offering nearly quantitative two-way isomerization with visible light
-
Bléger, D., Schwarz, J., Brouwer, A.M. & Hecht, S. o-Fluoroazobenzenes as readily synthesized photoswitches offering nearly quantitative two-way isomerization with visible light. J. Am. Chem. Soc. 134, 20597-20600 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 20597-20600
-
-
Bléger, D.1
Schwarz, J.2
Brouwer, A.M.3
Hecht, S.4
-
67
-
-
84874638018
-
Fluorescein analogues as photoremovable protecting groups absorbing at approximately 520 nm
-
Šebej, P. et al. Fluorescein analogues as photoremovable protecting groups absorbing at approximately 520 nm. J. Org. Chem. 78, 1833-1843 (2013).
-
(2013)
J. Org. Chem.
, vol.78
, pp. 1833-1843
-
-
Šebej, P.1
-
68
-
-
84890121904
-
Coumarinylmethyl caging groups with redshifted absorption
-
Fournier, L. et al. Coumarinylmethyl caging groups with redshifted absorption. Chemistry 19, 17494-17507 (2013).
-
(2013)
Chemistry
, vol.19
, pp. 17494-17507
-
-
Fournier, L.1
-
69
-
-
84886569127
-
Spectral evolution of a photochemical protecting group for orthogonal two-color uncaging with visible light
-
Olson, J.P., Banghart, M.R., Sabatini, B.L. & Ellis-Davies, G.C. Spectral evolution of a photochemical protecting group for orthogonal two-color uncaging with visible light. J. Am. Chem. Soc. 135, 15948-15954 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 15948-15954
-
-
Olson, J.P.1
Banghart, M.R.2
Sabatini, B.L.3
Ellis-Davies, G.C.4
-
70
-
-
84889264890
-
A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor
-
Kienzler, M.A. et al. A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor. J. Am. Chem. Soc. 135, 17683-17686 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 17683-17686
-
-
Kienzler, M.A.1
-
71
-
-
84865847445
-
Self-immolative spacer for uncaging with fluorescence reporting
-
Labruère, R. et al. "Self-immolative" spacer for uncaging with fluorescence reporting. Angew. Chem. Int. Edn Engl. 51, 9344-9347 (2012).
-
(2012)
Angew. Chem. Int. Edn Engl.
, vol.51
, pp. 9344-9347
-
-
Labruère, R.1
-
72
-
-
34247222730
-
Multimodal fast optical interrogation of neural circuitry
-
Zhang, F. et al. Multimodal fast optical interrogation of neural circuitry. Nature 446, 633-639 (2007).
-
(2007)
Nature
, vol.446
, pp. 633-639
-
-
Zhang, F.1
-
73
-
-
84858662491
-
Optogenetic investigation of neural circuits underlying brain disease in animal models
-
Tye, K.M. & Deisseroth, K. Optogenetic investigation of neural circuits underlying brain disease in animal models. Nat. Rev. Neurosci. 13, 251-266 (2012).
-
(2012)
Nat. Rev. Neurosci.
, vol.13
, pp. 251-266
-
-
Tye, K.M.1
Deisseroth, K.2
-
74
-
-
79954590792
-
Dual wavelength photoactivation of cAMP-And cGMP-dependent protein kinase signaling pathways
-
Priestman, M.A., Sun, L. & Lawrence, D.S. Dual wavelength photoactivation of cAMP-And cGMP-dependent protein kinase signaling pathways. ACS Chem. Biol. 6, 377-384 (2011).
-
(2011)
ACS Chem. Biol.
, vol.6
, pp. 377-384
-
-
Priestman, M.A.1
Sun, L.2
Lawrence, D.S.3
-
75
-
-
84892766255
-
Wavelength-selective one-And two-photon uncaging of GABA
-
Amatrudo, J.M. et al. Wavelength-selective one-And two-photon uncaging of GABA. ACS Chem. Neurosci. 5, 64-70 (2014).
-
(2014)
ACS Chem. Neurosci.
, vol.5
, pp. 64-70
-
-
Amatrudo, J.M.1
-
76
-
-
84880534465
-
A blue-Absorbing photolabile protecting group for in vivo chromatically orthogonal photoactivation
-
Fournier, L. et al. A blue-Absorbing photolabile protecting group for in vivo chromatically orthogonal photoactivation. ACS Chem. Biol. 8, 1528-1536 (2013).
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 1528-1536
-
-
Fournier, L.1
-
77
-
-
33745938554
-
Phytochrome structure and signaling mechanisms
-
Rockwell, N.C., Su, Y.S. & Lagarias, J.C. Phytochrome structure and signaling mechanisms. Annu. Rev. Plant Biol. 57, 837-858 (2006).
-
(2006)
Annu. Rev. Plant Biol.
, vol.57
, pp. 837-858
-
-
Rockwell, N.C.1
Su, Y.S.2
Lagarias, J.C.3
-
78
-
-
84861316505
-
Reversible photoswitching in fluorescent proteins: A mechanistic view
-
Bourgeois, D. & Adam, V. Reversible photoswitching in fluorescent proteins: A mechanistic view. IUBMB Life 64, 482-491 (2012).
-
(2012)
IUBMB Life
, vol.64
, pp. 482-491
-
-
Bourgeois, D.1
Adam, V.2
-
79
-
-
70350340730
-
Mechanism-based tuning of a LOV domain photoreceptor
-
Zoltowski, B.D., Vaccaro, B. & Crane, B.R. Mechanism-based tuning of a LOV domain photoreceptor. Nat. Chem. Biol. 5, 827-834 (2009).
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 827-834
-
-
Zoltowski, B.D.1
Vaccaro, B.2
Crane, B.R.3
-
80
-
-
67650566921
-
Conformational changes of channelrhodopsin-2
-
Radu, I. et al. Conformational changes of channelrhodopsin-2. J. Am. Chem. Soc. 131, 7313-7319 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 7313-7319
-
-
Radu, I.1
-
81
-
-
0037020424
-
Fluorescence spectroscopic quantification of the release of cyclic nucleotides from photocleavable [bis(carboxymethoxy)coumarin-4-yl]methyl esters inside cells
-
Hagen, V. et al. Fluorescence spectroscopic quantification of the release of cyclic nucleotides from photocleavable [bis(carboxymethoxy)coumarin-4-yl] methyl esters inside cells. Angew. Chem. Int. Edn Engl. 41, 3625-3628 (2002).
-
(2002)
Angew. Chem. Int. Edn Engl.
, vol.41
, pp. 3625-3628
-
-
Hagen, V.1
-
82
-
-
34250818700
-
Two-photon uncaging with the efficient 3,5-dibromo-2,4-dihydroxycinnamic caging group
-
Gagey, N., Neveu, P. & Jullien, L. Two-photon uncaging with the efficient 3,5-dibromo-2,4-dihydroxycinnamic caging group. Angew. Chem. Int. Edn Engl. 46, 2467-2469 (2007).
-
(2007)
Angew. Chem. Int. Edn Engl.
, vol.46
, pp. 2467-2469
-
-
Gagey, N.1
Neveu, P.2
Jullien, L.3
-
83
-
-
34547870514
-
Two-photon uncaging with fluorescence reporting: Evaluation of the o-hydroxycinnamic platform
-
Gagey, N. et al. Two-photon uncaging with fluorescence reporting: Evaluation of the o-hydroxycinnamic platform. J. Am. Chem. Soc. 129, 9986-9998 (2007).
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 9986-9998
-
-
Gagey, N.1
-
84
-
-
37549067797
-
Targeting and readout strategies for fast optical neural control in vitro and in vivo
-
Gradinaru, V. et al. Targeting and readout strategies for fast optical neural control in vitro and in vivo. J. Neurosci. 27, 14231-14238 (2007).
-
(2007)
J. Neurosci.
, vol.27
, pp. 14231-14238
-
-
Gradinaru, V.1
-
85
-
-
77955159501
-
Hold me tightly LOV
-
Hahn, K.M. & Kuhlman, B. Hold me tightly LOV. Nat. Methods 7, 595-596 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 595-596
-
-
Hahn, K.M.1
Kuhlman, B.2
-
86
-
-
80053465769
-
X-ray photolysis to release ligands from caged reagents by an intramolecular antenna sensitive to magnetic resonance imaging
-
Petit, M. et al. X-ray photolysis to release ligands from caged reagents by an intramolecular antenna sensitive to magnetic resonance imaging. Angew. Chem. Int. Edn Engl. 50, 9708-9711 (2011).
-
(2011)
Angew. Chem. Int. Edn Engl.
, vol.50
, pp. 9708-9711
-
-
Petit, M.1
-
87
-
-
79551666333
-
Ultrasound internal tattooing
-
Couture, O. et al. Ultrasound internal tattooing. Med. Phys. 38, 1116-1123 (2011).
-
(2011)
Med. Phys.
, vol.38
, pp. 1116-1123
-
-
Couture, O.1
-
88
-
-
0027630634
-
Targeted single-cell induction of gene products in Caenorhabditis elegans: A new tool for developmental studies
-
Stringham, E.G. & Candido, E.P. Targeted single-cell induction of gene products in Caenorhabditis elegans: A new tool for developmental studies. J. Exp. Zool. 266, 227-233 (1993).
-
(1993)
J. Exp. Zool.
, vol.266
, pp. 227-233
-
-
Stringham, E.G.1
Candido, E.P.2
-
89
-
-
0037012096
-
Selective photostimulation of genetically chARGed neurons
-
Zemelman, B.V., Lee, G.A., Ng, M. & Miesenbock, G. Selective photostimulation of genetically chARGed neurons. Neuron 33, 15-22 (2002).
-
(2002)
Neuron
, vol.33
, pp. 15-22
-
-
Zemelman, B.V.1
Lee, G.A.2
Ng, M.3
Miesenbock, G.4
-
90
-
-
84855190225
-
New channelrhodopsin with a red-shifted spectrum and rapid kinetics from Mesostigma viride
-
Govorunova, E.G., Spudich, E.N., Lane, C.E., Sineshchekov, O.A. & Spudich, J.L. New channelrhodopsin with a red-shifted spectrum and rapid kinetics from Mesostigma viride. MBio 2, e00115-11 (2011).
-
(2011)
MBio
, vol.2
-
-
Govorunova, E.G.1
Spudich, E.N.2
Lane, C.E.3
Sineshchekov, O.A.4
Spudich, J.L.5
-
91
-
-
0037189362
-
Channelrhodopsin-1: A light-gated proton channel in green algae
-
Nagel, G. et al. Channelrhodopsin-1: A light-gated proton channel in green algae. Science 296, 2395-2398 (2002).
-
(2002)
Science
, vol.296
, pp. 2395-2398
-
-
Nagel, G.1
-
92
-
-
44349120639
-
Red-shifted optogenetic excitation: A tool for fast neural control derived from Volvox carteri
-
Zhang, F. et al. Red-shifted optogenetic excitation: A tool for fast neural control derived from Volvox carteri. Nat. Neurosci. 11, 631-633 (2008).
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 631-633
-
-
Zhang, F.1
-
93
-
-
77950930288
-
Molecular and cellular approaches for diversifying and extending optogenetics
-
Gradinaru, V. et al. Molecular and cellular approaches for diversifying and extending optogenetics. Cell 141, 154-165 (2010).
-
(2010)
Cell
, vol.141
, pp. 154-165
-
-
Gradinaru, V.1
-
94
-
-
79957466415
-
Spatiotemporal control of small GTPases with light using the LOV domain
-
Wu, Y.I., Wang, X., He, L., Montell, D. & Hahn, K.M. Spatiotemporal control of small GTPases with light using the LOV domain. Methods Enzymol. 497, 393-407 (2011).
-
(2011)
Methods Enzymol.
, vol.497
, pp. 393-407
-
-
Wu, Y.I.1
Wang, X.2
He, L.3
Montell, D.4
Hahn, K.M.5
-
95
-
-
12744269340
-
Chemical actinometry (IUPAC Technical report)
-
Kuhn, H.J., Braslavsky, S.E. & Schmidt, R. Chemical actinometry (IUPAC Technical report). Pure Appl. Chem. 76, 2105-2146 (2004).
-
(2004)
Pure Appl. Chem.
, vol.76
, pp. 2105-2146
-
-
Kuhn, H.J.1
Braslavsky, S.E.2
Schmidt, R.3
-
97
-
-
33845555333
-
Two-photon molecular spectroscopy
-
Friedrich, D.M. Two-photon molecular spectroscopy. J. Chem. Educ. 59, 472-481 (1982).
-
(1982)
J. Chem. Educ.
, vol.59
, pp. 472-481
-
-
Friedrich, D.M.1
-
98
-
-
0242353872
-
Nonlinear magic: Multiphoton microscopy in the biosciences
-
Zipfel, W.R., Williams, R.M. & Webb, W.W. Nonlinear magic: Multiphoton microscopy in the biosciences. Nat. Biotechnol. 21, 1369-1377 (2003).
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1369-1377
-
-
Zipfel, W.R.1
Williams, R.M.2
Webb, W.W.3
-
99
-
-
0030532990
-
Measurement of two-photon excitation cross sections of molecular fluorophores with data from 690 nm to 1050 nm
-
Xu, W.R. & Webb, W.W. Measurement of two-photon excitation cross sections of molecular fluorophores with data from 690 nm to 1050 nm. J. Opt. Soc. Am. B 13, 481-491 (1996).
-
(1996)
J. Opt. Soc. Am.
, vol.B13
, pp. 481-491
-
-
Xu, W.R.1
Webb, W.W.2
-
100
-
-
77449119514
-
Two-color two-photon uncaging of glutamate and GABA
-
Kantevari, S., Matsuzaki, M., Kanemoto, Y., Kasai, H. & Ellis-Davies, G.C. Two-color, two-photon uncaging of glutamate and GABA. Nat. Methods 7, 123-125 (2010).
-
(2010)
Nat. Methods
, vol.7
, pp. 123-125
-
-
Kantevari, S.1
Matsuzaki, M.2
Kanemoto, Y.3
Kasai, H.4
Ellis-Davies, G.C.5
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