-
1
-
-
84883461399
-
New clinical trial designs for HIV vaccine evaluation
-
Moodie Z, Janes H, Huang Y. New clinical trial designs for HIV vaccine evaluation. Curr Opin HIV AIDS 2013;8:436-41.
-
(2013)
Curr Opin HIV AIDS
, vol.8
, pp. 436-441
-
-
Moodie, Z.1
Janes, H.2
Huang, Y.3
-
2
-
-
84859166440
-
Evaluating immune correlates in HIV type 1 vaccine efficacy trials: what RV144 may provide
-
Rolland M, Gilbert P. Evaluating immune correlates in HIV type 1 vaccine efficacy trials: what RV144 may provide. AIDS Res Hum Retroviruses 2012;28:400-4.
-
(2012)
AIDS Res Hum Retroviruses
, vol.28
, pp. 400-404
-
-
Rolland, M.1
Gilbert, P.2
-
3
-
-
84871403286
-
Basic research in HIV vaccinology is hampered by reductionist thinking
-
Van Regenmortel MH. Basic research in HIV vaccinology is hampered by reductionist thinking. Front Immunol 2012;3:194.
-
(2012)
Front Immunol
, vol.3
, pp. 194
-
-
Van Regenmortel, M.H.1
-
5
-
-
84883462326
-
New directions for HIV vaccine development from animal models
-
McChesney MB, Miller CJ. New directions for HIV vaccine development from animal models. Curr Opin HIV AIDS 2013;8:376-81.
-
(2013)
Curr Opin HIV AIDS
, vol.8
, pp. 376-381
-
-
McChesney, M.B.1
Miller, C.J.2
-
6
-
-
84856482137
-
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys
-
Barouch DH, Liu J, Li H et al. Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys. Nature. 2012;482:89-93.
-
(2012)
Nature
, vol.482
, pp. 89-93
-
-
Barouch, D.H.1
Liu, J.2
Li, H.3
-
7
-
-
84883689744
-
Cell-mediated immunity in elite controllers naturally controlling HIV viral load
-
Genovese L, Nebuloni M, Alfano M. Cell-mediated immunity in elite controllers naturally controlling HIV viral load. Front Immunol 2013;4:86.
-
(2013)
Front Immunol
, vol.4
, pp. 86
-
-
Genovese, L.1
Nebuloni, M.2
Alfano, M.3
-
8
-
-
0037439522
-
Cellular human immunodeficiency virus (HIV)-protective factors: a comparison of HIV-exposed seronegative female sex workers and female blood donors in Abidjan, Côte d'Ivoire
-
Jennes W, Sawadogo S, Koblavi-Dème S et al. Cellular human immunodeficiency virus (HIV)-protective factors: a comparison of HIV-exposed seronegative female sex workers and female blood donors in Abidjan, Côte d'Ivoire. J Infect Dis 2003;187:206-14.
-
(2003)
J Infect Dis
, vol.187
, pp. 206-214
-
-
Jennes, W.1
Sawadogo, S.2
Koblavi-Dème, S.3
-
9
-
-
16044367526
-
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
-
Huang Y, Paxton WA, Wolinsky SM et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996;2:1240-3.
-
(1996)
Nat Med
, vol.2
, pp. 1240-1243
-
-
Huang, Y.1
Paxton, W.A.2
Wolinsky, S.M.3
-
10
-
-
84892365659
-
Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
-
Hraber P, Seaman MS, Bailer RT, Mascola JR, Montefiori DC, Korber BT. Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection. AIDS 2014;28:163-9.
-
(2014)
AIDS
, vol.28
, pp. 163-169
-
-
Hraber, P.1
Seaman, M.S.2
Bailer, R.T.3
Mascola, J.R.4
Montefiori, D.C.5
Korber, B.T.6
-
11
-
-
84865997747
-
Expansion of HIV-specific T follicular helper cells in chronic HIV infection
-
Lindqvist M, van Lunzen J, Soghoian DZ et al. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J Clin Invest. 2012;122:3271-80.
-
(2012)
J Clin Invest
, vol.122
, pp. 3271-3280
-
-
Lindqvist, M.1
van Lunzen, J.2
Soghoian, D.Z.3
-
12
-
-
84883796903
-
Antibodies in HIV-1 vaccine development and therapy
-
Klein F, Mouquet H, Dosenovic P, Scheid JF, Scharf L, Nussenzweig MC. Antibodies in HIV-1 vaccine development and therapy. Science 2013;341:1199-204.
-
(2013)
Science
, vol.341
, pp. 1199-1204
-
-
Klein, F.1
Mouquet, H.2
Dosenovic, P.3
Scheid, J.F.4
Scharf, L.5
Nussenzweig, M.C.6
-
13
-
-
67650453747
-
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
-
Simek MD, Rida W, Priddy FH et al. Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. J Virol 2009;83:7337-48.
-
(2009)
J Virol
, vol.83
, pp. 7337-7348
-
-
Simek, M.D.1
Rida, W.2
Priddy, F.H.3
-
14
-
-
84877626973
-
Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth
-
Murphy MK, Yue L, Pan R et al. Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth. PLoS Pathog 2013;9:e1003173.
-
(2013)
PLoS Pathog
, vol.9
-
-
Murphy, M.K.1
Yue, L.2
Pan, R.3
-
15
-
-
84876797103
-
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
-
Liao HX, Lynch R, Zhou T et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature. 2013;496:469-76.
-
(2013)
Nature
, vol.496
, pp. 469-476
-
-
Liao, H.X.1
Lynch, R.2
Zhou, T.3
-
16
-
-
84875759341
-
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
-
Klein F, Diskin R, Scheid JF et al. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell 2013;153:126-38.
-
(2013)
Cell
, vol.153
, pp. 126-138
-
-
Klein, F.1
Diskin, R.2
Scheid, J.F.3
-
17
-
-
84875034460
-
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9
-
Julien JP, Lee JH, Cupo A et al. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proc Natl Acad Sci USA 2013;110:4351-6.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 4351-4356
-
-
Julien, J.P.1
Lee, J.H.2
Cupo, A.3
-
18
-
-
73949154006
-
Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L
-
Hessell AJ, Rakasz EG, Tehrani DM et al. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. J Virol 2010;84:1302-13.
-
(2010)
J Virol
, vol.84
, pp. 1302-1313
-
-
Hessell, A.J.1
Rakasz, E.G.2
Tehrani, D.M.3
-
19
-
-
84866493348
-
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
-
Huang J, Ofek G, Laub L et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature 2012;491:406-12.
-
(2012)
Nature
, vol.491
, pp. 406-412
-
-
Huang, J.1
Ofek, G.2
Laub, L.3
-
20
-
-
84864621158
-
Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function
-
Guenaga J, Wyatt RT. Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function. PLoS Pathog 2012;8:e1002806.
-
(2012)
PLoS Pathog
, vol.8
-
-
Guenaga, J.1
Wyatt, R.T.2
-
21
-
-
84874561170
-
Neutralizing antibodies to HIV-1 induced by immunization
-
McCoy LE, Weiss RA. Neutralizing antibodies to HIV-1 induced by immunization. J Exp Med 2013;210:209-23.
-
(2013)
J Exp Med
, vol.210
, pp. 209-223
-
-
McCoy, L.E.1
Weiss, R.A.2
-
23
-
-
77249085588
-
Role of humoral immunity in host defense against HIV
-
Baum LL. Role of humoral immunity in host defense against HIV. Curr HIV/AIDS Rep 2010;7:11-8.
-
(2010)
Curr HIV/AIDS Rep
, vol.7
, pp. 11-18
-
-
Baum, L.L.1
-
25
-
-
69549103041
-
Fc receptor-mediated antiviral antibodies
-
Forthal DN, Moog C. Fc receptor-mediated antiviral antibodies. Curr Opin HIV AIDS 2009;4:388-93.
-
(2009)
Curr Opin HIV AIDS
, vol.4
, pp. 388-393
-
-
Forthal, D.N.1
Moog, C.2
-
26
-
-
84866681537
-
Comprehensive investigation of common antibody-dependent cell-mediated cytotoxicity antibody epitopes of HIV-1 CRF01_AE gp120
-
Ampol S, Pattanapanyasat K, Sutthent R, Permpikul P, Kantakamalakul W. Comprehensive investigation of common antibody-dependent cell-mediated cytotoxicity antibody epitopes of HIV-1 CRF01_AE gp120. AIDS Res Hum Retroviruses 2012;28:1250-8.
-
(2012)
AIDS Res Hum Retroviruses
, vol.28
, pp. 1250-1258
-
-
Ampol, S.1
Pattanapanyasat, K.2
Sutthent, R.3
Permpikul, P.4
Kantakamalakul, W.5
-
27
-
-
80052586083
-
HIV vaccine development-improving on natural immunity
-
Johnston MI, Fauci AS. HIV vaccine development-improving on natural immunity. N Engl J Med 2011;365:873-5.
-
(2011)
N Engl J Med
, vol.365
, pp. 873-875
-
-
Johnston, M.I.1
Fauci, A.S.2
-
28
-
-
84880761366
-
Mapping the journey to an HIV vaccine
-
Ackerman M, Alter G. Mapping the journey to an HIV vaccine. N Engl J Med 2013;369:389-91.
-
(2013)
N Engl J Med
, vol.369
, pp. 389-391
-
-
Ackerman, M.1
Alter, G.2
-
29
-
-
84890899378
-
Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques
-
Moog C, Dereuddre-Bosquet N, Teillaud JL et al. Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques. Mucosal Immunol 2014;7:46-56.
-
(2014)
Mucosal Immunol
, vol.7
, pp. 46-56
-
-
Moog, C.1
Dereuddre-Bosquet, N.2
Teillaud, J.L.3
-
30
-
-
84860389036
-
The gp41 epitope, QARVLAVERY, is highly conserved and a potent inducer of IgA that neutralizes HIV-1 and inhibits viral transcytosis
-
Jain S, Rosenthal KL. The gp41 epitope, QARVLAVERY, is highly conserved and a potent inducer of IgA that neutralizes HIV-1 and inhibits viral transcytosis. Mucosal Immunol 2011;4:539-53.
-
(2011)
Mucosal Immunol
, vol.4
, pp. 539-553
-
-
Jain, S.1
Rosenthal, K.L.2
-
31
-
-
79551649723
-
A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers
-
Hunt PW, Landay AL, Sinclair E et al. A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. PLoS ONE 2011;6:e15924.
-
(2011)
PLoS ONE
, vol.6
-
-
Hunt, P.W.1
Landay, A.L.2
Sinclair, E.3
-
32
-
-
84861312708
-
Differential Gag-specific polyfunctional T cell maturation patterns in HIV-1 elite controllers
-
Ferrando-Martínez S, Casazza JP, Leal M et al. Differential Gag-specific polyfunctional T cell maturation patterns in HIV-1 elite controllers. J Virol 2012;86:3667-74.
-
(2012)
J Virol
, vol.86
, pp. 3667-3674
-
-
Ferrando-Martínez, S.1
Casazza, J.P.2
Leal, M.3
-
33
-
-
84873531162
-
Harnessing CD4 T cell responses in HIV vaccine development
-
Streeck H, D'Souza MP, Littman DR, Crotty S. Harnessing CD4 T cell responses in HIV vaccine development. Nat Med 2013;19:143-9.
-
(2013)
Nat Med
, vol.19
, pp. 143-149
-
-
Streeck, H.1
D'Souza, M.P.2
Littman, D.R.3
Crotty, S.4
-
34
-
-
78650084232
-
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
-
International HIV Controllers Study
-
International HIV Controllers Study. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 2010;330:1551-7.
-
(2010)
Science
, vol.330
, pp. 1551-1557
-
-
-
36
-
-
79958051220
-
The antiviral efficacy of HIV-specific CD8 T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate
-
Ranasinghe SR, Kramer HB, Wright C et al. The antiviral efficacy of HIV-specific CD8 T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate. PLoS Pathog 2011;7:e1001341.
-
(2011)
PLoS Pathog
, vol.7
-
-
Ranasinghe, S.R.1
Kramer, H.B.2
Wright, C.3
-
37
-
-
65749116175
-
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
-
Tenzer S, Wee E, Burgevin A et al. Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance. Nat Immunol 2009;10:636-46.
-
(2009)
Nat Immunol
, vol.10
, pp. 636-646
-
-
Tenzer, S.1
Wee, E.2
Burgevin, A.3
-
38
-
-
0024253387
-
Immunization against the human immunodeficiency virus in Zaire
-
Zagury D, Salaün JJ, Bernard J, Dechazal L, Goussard B, Lurhuma Z. Immunization against the human immunodeficiency virus in Zaire. Med Trop (Mars) 1988;48:417-23.
-
(1988)
Med Trop (Mars)
, vol.48
, pp. 417-423
-
-
Zagury, D.1
Salaün, J.J.2
Bernard, J.3
Dechazal, L.4
Goussard, B.5
Lurhuma, Z.6
-
39
-
-
84880714310
-
A brief history of the global effort to develop a preventive HIV vaccine
-
Esparza J. A brief history of the global effort to develop a preventive HIV vaccine. Vaccine 2013;31:3502-18.
-
(2013)
Vaccine
, vol.31
, pp. 3502-3518
-
-
Esparza, J.1
-
40
-
-
84883460283
-
Novel directions in HIV-1 vaccines revealed from clinical trials
-
Excler JL, Tomaras GD, Russell ND. Novel directions in HIV-1 vaccines revealed from clinical trials. Curr Opin HIV AIDS 2013;8:420-30.
-
(2013)
Curr Opin HIV AIDS
, vol.8
, pp. 420-430
-
-
Excler, J.L.1
Tomaras, G.D.2
Russell, N.D.3
-
41
-
-
84902666477
-
-
September 16
-
http://www.iavireport.org/Trials-Database/Pages/Results.aspx?searchid=8842fd6b-b1dd-4286-be8f-4b29b834bef1. September 16, 2013.
-
-
-
-
42
-
-
84877739033
-
Human immunodeficiency virus vaccine an update
-
Beena V, Choudhary K, Rajeev R, Sivakumar R, Heera R, Padmakumar S. Human immunodeficiency virus vaccine an update. J Oral Maxillofac Pathol 2013;17:76-81.
-
(2013)
J Oral Maxillofac Pathol
, vol.17
, pp. 76-81
-
-
Beena, V.1
Choudhary, K.2
Rajeev, R.3
Sivakumar, R.4
Heera, R.5
Padmakumar, S.6
-
43
-
-
84862732215
-
The design and evaluation of HIV-1 vaccines
-
Saunders KO, Rudicell RS, Nabel GJ. The design and evaluation of HIV-1 vaccines. AIDS 2012;26:1293-302.
-
(2012)
AIDS
, vol.26
, pp. 1293-1302
-
-
Saunders, K.O.1
Rudicell, R.S.2
Nabel, G.J.3
-
45
-
-
84895506447
-
An overview of adjuvant formulations and delivery systems
-
García A, De Sanctis JB. An overview of adjuvant formulations and delivery systems. APMIS 2013;122:257-67.
-
(2013)
APMIS
, vol.122
, pp. 257-267
-
-
García, A.1
De Sanctis, J.B.2
-
46
-
-
80054860177
-
Toll-like receptor agonists as adjuvants for HIV vaccines
-
Stevceva L. Toll-like receptor agonists as adjuvants for HIV vaccines. Curr Med Chem 2011;18:5079-82.
-
(2011)
Curr Med Chem
, vol.18
, pp. 5079-5082
-
-
Stevceva, L.1
-
47
-
-
84883599595
-
Boosters of a therapeutic HIV-1 vaccine induce divergent T cell responses related to regulatory mechanisms
-
Lind A, Brekke K, Sommerfelt M et al. Boosters of a therapeutic HIV-1 vaccine induce divergent T cell responses related to regulatory mechanisms. Vaccine 2013;31:4611-8.
-
(2013)
Vaccine
, vol.31
, pp. 4611-4618
-
-
Lind, A.1
Brekke, K.2
Sommerfelt, M.3
-
48
-
-
79959198170
-
Immunologic considerations for generating memory CD8 T cells through vaccination
-
Butler NS, Nolz JC, Harty JT. Immunologic considerations for generating memory CD8 T cells through vaccination. Cell Microbiol 2011;13:925-33.
-
(2011)
Cell Microbiol
, vol.13
, pp. 925-933
-
-
Butler, N.S.1
Nolz, J.C.2
Harty, J.T.3
-
49
-
-
84887445284
-
Dendritic cell based vaccines for HIV infection: The way ahead
-
García F, Plana M, Climent N, León A, Gatell JM, Gallart T. Dendritic cell based vaccines for HIV infection: The way ahead. Hum Vaccin Immunother 2013;9:2445-52.
-
(2013)
Hum Vaccin Immunother
, vol.9
, pp. 2445-2452
-
-
García, F.1
Plana, M.2
Climent, N.3
León, A.4
Gatell, J.M.5
Gallart, T.6
-
50
-
-
84862770549
-
HIV reservoirs: pathogenesis and obstacles to viral eradication and cure
-
Chun TW, Fauci AS. HIV reservoirs: pathogenesis and obstacles to viral eradication and cure. AIDS 2012;26:1261-8.
-
(2012)
AIDS
, vol.26
, pp. 1261-1268
-
-
Chun, T.W.1
Fauci, A.S.2
-
51
-
-
84890114191
-
Establishment and molecular mechanisms of HIV-1 latency in T cells
-
van der Sluis RM, Jeeninga RE, Berkhout B. Establishment and molecular mechanisms of HIV-1 latency in T cells. Curr Opin Virol 2013;3:700-6.
-
(2013)
Curr Opin Virol
, vol.3
, pp. 700-706
-
-
van der Sluis, R.M.1
Jeeninga, R.E.2
Berkhout, B.3
-
52
-
-
77949264937
-
Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys
-
Santra S, Liao HX, Zhang R et al. Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. Nat Med 2010;16:324-8.
-
(2010)
Nat Med
, vol.16
, pp. 324-328
-
-
Santra, S.1
Liao, H.X.2
Zhang, R.3
-
53
-
-
77949263061
-
Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys
-
Barouch DH, O'Brien KL, Simmons NL et al. Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys. Nat Med 2010;16:319-23.
-
(2010)
Nat Med
, vol.16
, pp. 319-323
-
-
Barouch, D.H.1
O'Brien, K.L.2
Simmons, N.L.3
-
54
-
-
84879290459
-
A global approach to HIV-1 vaccine development
-
Stephenson KE, Barouch DH. A global approach to HIV-1 vaccine development. Immunol Rev 2013;254:295-304.
-
(2013)
Immunol Rev
, vol.254
, pp. 295-304
-
-
Stephenson, K.E.1
Barouch, D.H.2
-
55
-
-
84879471170
-
Comparative immunogenicity of evolved V1V2-deleted HIV-1 envelope glycoprotein trimers
-
Bontjer I, Melchers M, Tong T et al. Comparative immunogenicity of evolved V1V2-deleted HIV-1 envelope glycoprotein trimers. PLoS ONE 2013;8:e67484.
-
(2013)
PLoS ONE
, vol.8
-
-
Bontjer, I.1
Melchers, M.2
Tong, T.3
-
56
-
-
84859393693
-
Immune-correlates analysis of an HIV-1 vaccine efficacy trial
-
Haynes BF, Gilbert PB, McElrath MJ et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 2012;366:1275-86.
-
(2012)
N Engl J Med
, vol.366
, pp. 1275-1286
-
-
Haynes, B.F.1
Gilbert, P.B.2
McElrath, M.J.3
-
57
-
-
79958728198
-
Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimetic
-
Martin G, Burke B, Thaï R et al. Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimetic. J Biol Chem 2011;286:21706-16.
-
(2011)
J Biol Chem
, vol.286
, pp. 21706-21716
-
-
Martin, G.1
Burke, B.2
Thaï, R.3
-
58
-
-
0024844908
-
A formalin-inactivated whole SIV vaccine confers protection in macaques
-
Murphey-Corb M, Martin LN, Davison-Fairburn B et al. A formalin-inactivated whole SIV vaccine confers protection in macaques. Science 1989;246:1293-7.
-
(1989)
Science
, vol.246
, pp. 1293-1297
-
-
Murphey-Corb, M.1
Martin, L.N.2
Davison-Fairburn, B.3
-
59
-
-
0027043276
-
Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
-
Daniel MD, Kirchhoff F, Czajak SC, Sehgal PK, Desrosiers RC. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 1992;258:1938-41.
-
(1992)
Science
, vol.258
, pp. 1938-1941
-
-
Daniel, M.D.1
Kirchhoff, F.2
Czajak, S.C.3
Sehgal, P.K.4
Desrosiers, R.C.5
-
60
-
-
0032849066
-
Protection by live, attenuated simian immunodeficiency virus against heterologous challenge
-
Wyand MS, Manson K, Montefiori DC, Lifson JD, Johnson RP, Desrosiers RC. Protection by live, attenuated simian immunodeficiency virus against heterologous challenge. J Virol 1999;73:8356-63.
-
(1999)
J Virol
, vol.73
, pp. 8356-8363
-
-
Wyand, M.S.1
Manson, K.2
Montefiori, D.C.3
Lifson, J.D.4
Johnson, R.P.5
Desrosiers, R.C.6
-
61
-
-
0035853080
-
Live attenuated HIV vaccines: predicting the tradeoff between efficacy and safety
-
Blower SM, Koelle K, Kirschner DE, Mills J. Live attenuated HIV vaccines: predicting the tradeoff between efficacy and safety. Proc Natl Acad Sci USA 2001;98:3618-23.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3618-3623
-
-
Blower, S.M.1
Koelle, K.2
Kirschner, D.E.3
Mills, J.4
-
62
-
-
84883400877
-
Development of replication-competent viral vectors for HIV vaccine delivery
-
Parks CL, Picker LJ, King CR. Development of replication-competent viral vectors for HIV vaccine delivery. Curr Opin HIV AIDS 2013;8:401-10.
-
(2013)
Curr Opin HIV AIDS
, vol.8
, pp. 401-410
-
-
Parks, C.L.1
Picker, L.J.2
King, C.R.3
-
63
-
-
13944254982
-
Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
-
rgp120 HIV Vaccine Study Group
-
Flynn NM, Forthal DN, Harro CD, Judson FN, Mayer KH, Para MF; rgp120 HIV Vaccine Study Group. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis. 2005;191:654-65.
-
(2005)
J Infect Dis
, vol.191
, pp. 654-665
-
-
Flynn, N.M.1
Forthal, D.N.2
Harro, C.D.3
Judson, F.N.4
Mayer, K.H.5
Para, M.F.6
-
65
-
-
33845433434
-
Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
-
Pitisuttithum P, Gilbert P, Gurwith M et al. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J Infect Dis. 2006;194:1661-71.
-
(2006)
J Infect Dis
, vol.194
, pp. 1661-1671
-
-
Pitisuttithum, P.1
Gilbert, P.2
Gurwith, M.3
-
66
-
-
34248168722
-
Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rate
-
Forthal DN, Gilbert PB, Landucci G, Phan T. Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rate. J Immunol 2007;178:6596-603.
-
(2007)
J Immunol
, vol.178
, pp. 6596-6603
-
-
Forthal, D.N.1
Gilbert, P.B.2
Landucci, G.3
Phan, T.4
-
67
-
-
78149432061
-
Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody
-
Cheong C, Choi JH, Vitale L et al. Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody. Blood 2010;116:3828-38.
-
(2010)
Blood
, vol.116
, pp. 3828-3838
-
-
Cheong, C.1
Choi, J.H.2
Vitale, L.3
-
68
-
-
84883874246
-
Lipoidal soft hybrid biocarriers of supramolecular construction for drug delivery
-
Kumar D, Sharma D, Singh G, Singh M, Rathore MS. Lipoidal soft hybrid biocarriers of supramolecular construction for drug delivery. ISRN Pharm 2012;2012:474830.
-
(2012)
ISRN Pharm
, vol.2012
, pp. 474830
-
-
Kumar, D.1
Sharma, D.2
Singh, G.3
Singh, M.4
Rathore, M.S.5
-
69
-
-
84862309329
-
Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41
-
Pastori C, Tudor D, Diomede L et al. Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41. Virology 2012;431:1-11.
-
(2012)
Virology
, vol.431
, pp. 1-11
-
-
Pastori, C.1
Tudor, D.2
Diomede, L.3
-
70
-
-
84879530209
-
Improving adaptive and memory immune responses of an HIV/AIDS vaccine candidate MVA-B by deletion of vaccinia virus genes (C6L and K7R) blocking interferon signaling pathways
-
García-Arriaza J, Arnáez P, Gómez CE, Sorzano CO, Esteban M. Improving adaptive and memory immune responses of an HIV/AIDS vaccine candidate MVA-B by deletion of vaccinia virus genes (C6L and K7R) blocking interferon signaling pathways. PLoS ONE. 2013;8:e66894.
-
(2013)
PLoS ONE
, vol.8
-
-
García-Arriaza, J.1
Arnáez, P.2
Gómez, C.E.3
Sorzano, C.O.4
Esteban, M.5
-
71
-
-
84872324423
-
Recombinant vaccines and the development of new vaccine strategies
-
Nascimento IP, Leite LC. Recombinant vaccines and the development of new vaccine strategies. Braz J Med Biol Res 2012;45:1102-11.
-
(2012)
Braz J Med Biol Res
, vol.45
, pp. 1102-1111
-
-
Nascimento, I.P.1
Leite, L.C.2
-
72
-
-
84882922175
-
Modified Vaccinia virus Ankara: Innate immune activation and induction of cellular signalling
-
Price PJ, Torres-Domínguez LE, Brandmüller C, Sutter G, Lehmann MH. Modified Vaccinia virus Ankara: Innate immune activation and induction of cellular signalling. Vaccine 2013;31:4231-4.
-
(2013)
Vaccine
, vol.31
, pp. 4231-4234
-
-
Price, P.J.1
Torres-Domínguez, L.E.2
Brandmüller, C.3
Sutter, G.4
Lehmann, M.H.5
-
73
-
-
84902666469
-
-
March 31
-
http://clinicaltrials.gov/show/NCT01215149. March 31, 2014.
-
(2014)
-
-
-
74
-
-
77949564415
-
Adenovirus 5 serotype vector-specific immunity and HIV-1 infection: a tale of T cells and antibodies
-
D'Souza MP, Frahm N. Adenovirus 5 serotype vector-specific immunity and HIV-1 infection: a tale of T cells and antibodies. AIDS 2010;24:803-9.
-
(2010)
AIDS
, vol.24
, pp. 803-809
-
-
D'Souza, M.P.1
Frahm, N.2
-
76
-
-
56649114351
-
HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis
-
McElrath MJ, De Rosa SC, Moodie Z et al. HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis. Lancet 2008;372:1894-905.
-
(2008)
Lancet
, vol.372
, pp. 1894-1905
-
-
McElrath, M.J.1
De Rosa, S.C.2
Moodie, Z.3
-
77
-
-
56649105122
-
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder SP, Mehrotra DV, Duerr A et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 2008;372:1881-93.
-
(2008)
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
Mehrotra, D.V.2
Duerr, A.3
-
78
-
-
68349135329
-
Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans
-
O'Brien KL, Liu J, King SL et al. Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans. Nat Med 2009;15:873-5.
-
(2009)
Nat Med
, vol.15
, pp. 873-875
-
-
O'Brien, K.L.1
Liu, J.2
King, S.L.3
-
79
-
-
77955513770
-
Overview of STEP and Phambili trial results: two phase IIb test-of-concept studies investigating the efficacy of MRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine
-
Gray G, Buchbinder S, Duerr A. Overview of STEP and Phambili trial results: two phase IIb test-of-concept studies investigating the efficacy of MRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine. Curr Opin HIV AIDS 2010;5:357-61.
-
(2010)
Curr Opin HIV AIDS
, vol.5
, pp. 357-361
-
-
Gray, G.1
Buchbinder, S.2
Duerr, A.3
-
80
-
-
77956799959
-
Mucosal trafficking of vector-specific CD4+ T lymphocytes following vaccination of rhesus monkeys with adenovirus serotype 5
-
Masek-Hammerman K, Li H, Liu J et al. Mucosal trafficking of vector-specific CD4+ T lymphocytes following vaccination of rhesus monkeys with adenovirus serotype 5. J Virol 2010;84:9810-6.
-
(2010)
J Virol
, vol.84
, pp. 9810-9816
-
-
Masek-Hammerman, K.1
Li, H.2
Liu, J.3
-
81
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 2009;361:2209-20.
-
(2009)
N Engl J Med
, vol.361
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
Pitisuttithum, P.2
Nitayaphan, S.3
-
82
-
-
84902666470
-
-
March 31
-
http://clinicaltrials.gov/show/NCT00223080. March 31, 2014.
-
(2014)
-
-
-
83
-
-
84861173075
-
The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope
-
de Souza MS, Ratto-Kim S, Chuenarom W et al. The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope. J Immunol 2012;188:5166-76.
-
(2012)
J Immunol
, vol.188
, pp. 5166-5176
-
-
de Souza, M.S.1
Ratto-Kim, S.2
Chuenarom, W.3
-
84
-
-
77956481715
-
Phase III HIV vaccine trial in Thailand: a step toward a protective vaccine for HIV
-
Vaccari M, Poonam P, Franchini G. Phase III HIV vaccine trial in Thailand: a step toward a protective vaccine for HIV. Expert Rev Vaccines 2010;9:997-1005.
-
(2010)
Expert Rev Vaccines
, vol.9
, pp. 997-1005
-
-
Vaccari, M.1
Poonam, P.2
Franchini, G.3
-
85
-
-
84880310997
-
Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccines
-
Liu P, Yates NL, Shen X et al. Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccines. J Virol 2013;87:7828-36.
-
(2013)
J Virol
, vol.87
, pp. 7828-7836
-
-
Liu, P.1
Yates, N.L.2
Shen, X.3
-
86
-
-
80051564046
-
Human immunodeficiency virus (HIV) immunopathogenesis and vaccine development: a review
-
Girard MP, Osmanov S, Assossou OM, Kieny MP. Human immunodeficiency virus (HIV) immunopathogenesis and vaccine development: a review. Vaccine 2011;29:6191-218.
-
(2011)
Vaccine
, vol.29
, pp. 6191-6218
-
-
Girard, M.P.1
Osmanov, S.2
Assossou, O.M.3
Kieny, M.P.4
-
87
-
-
84869830733
-
HIV-specific antibody-dependent cellular cytotoxicity: a novel vaccine modality
-
Madhavi V, Kent SJ, Stratov I. HIV-specific antibody-dependent cellular cytotoxicity: a novel vaccine modality. Expert Rev Clin Immunol 2012;8:767-74.
-
(2012)
Expert Rev Clin Immunol
, vol.8
, pp. 767-774
-
-
Madhavi, V.1
Kent, S.J.2
Stratov, I.3
-
89
-
-
84885142956
-
DNA vaccines: A simple DNA sensing matter?
-
Coban C, Kobiyama K, Jounai N, Tozuka M, Ishii KJ. DNA vaccines: A simple DNA sensing matter? Hum Vaccin Immunother. 2013;9: 2216-21.
-
(2013)
Hum Vaccin Immunother
, vol.9
, pp. 2216-2221
-
-
Coban, C.1
Kobiyama, K.2
Jounai, N.3
Tozuka, M.4
Ishii, K.J.5
-
90
-
-
84881623207
-
Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery
-
Kalams SA, Parker SD, Elizaga M et al. Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery. J Infect Dis 2013;208:818-29.
-
(2013)
J Infect Dis
, vol.208
, pp. 818-829
-
-
Kalams, S.A.1
Parker, S.D.2
Elizaga, M.3
-
91
-
-
84878552360
-
PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8+ T cells in mice
-
Zhou J, Cheung AK, Tan Z et al. PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8+ T cells in mice. J Clin Invest 2013;123:2629-42.
-
(2013)
J Clin Invest
, vol.123
, pp. 2629-2642
-
-
Zhou, J.1
Cheung, A.K.2
Tan, Z.3
-
92
-
-
84881424278
-
Potent T cell responses induced by single DNA vaccine boosted with recombinant vaccinia vaccine
-
Liu L, Qiu C, Huang Y, Xu J, Shao Y. Potent T cell responses induced by single DNA vaccine boosted with recombinant vaccinia vaccine. Virol Sin 2013;28:109-15.
-
(2013)
Virol Sin
, vol.28
, pp. 109-115
-
-
Liu, L.1
Qiu, C.2
Huang, Y.3
Xu, J.4
Shao, Y.5
-
93
-
-
84877704918
-
Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant
-
Li M, Jiang Y, Xu C, Zhang Z, Sun X. Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant. Int J Nanomedicine 2013;8:1843-54.
-
(2013)
Int J Nanomedicine
, vol.8
, pp. 1843-1854
-
-
Li, M.1
Jiang, Y.2
Xu, C.3
Zhang, Z.4
Sun, X.5
-
94
-
-
84880927219
-
HIV/SIV DNA vaccine combined with protein in a co-immunization protocol elicits highest humoral responses to envelope in mice and macaques
-
Li J, Valentin A, Kulkarni V et al. HIV/SIV DNA vaccine combined with protein in a co-immunization protocol elicits highest humoral responses to envelope in mice and macaques. Vaccine 2013;31:3747-55.
-
(2013)
Vaccine
, vol.31
, pp. 3747-3755
-
-
Li, J.1
Valentin, A.2
Kulkarni, V.3
-
95
-
-
84887865083
-
Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine
-
Hammer SM, Sobieszczyk ME, Janes H et al. Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine. N Engl J Med. 2013; 369: 2083-92.
-
(2013)
N Engl J Med
, vol.369
, pp. 2083-2092
-
-
Hammer, S.M.1
Sobieszczyk, M.E.2
Janes, H.3
-
96
-
-
76749160185
-
Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen
-
Henriksen-Lacey M, Bramwell VW, Christensen D, Agger EM, Andersen P, Perrie Y. Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen. J Control Release 2010;142:180-6.
-
(2010)
J Control Release
, vol.142
, pp. 180-186
-
-
Henriksen-Lacey, M.1
Bramwell, V.W.2
Christensen, D.3
Agger, E.M.4
Andersen, P.5
Perrie, Y.6
-
97
-
-
84857785011
-
Design considerations for liposomal vaccines: influence of formulation parameters on antibody and cell-mediated immuneresponses to liposome associated antigens
-
Watson DS, Endsley AN, Huang L. Design considerations for liposomal vaccines: influence of formulation parameters on antibody and cell-mediated immuneresponses to liposome associated antigens. Vaccine 2012;30:2256-72.
-
(2012)
Vaccine
, vol.30
, pp. 2256-2272
-
-
Watson, D.S.1
Endsley, A.N.2
Huang, L.3
-
98
-
-
79951754740
-
Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges
-
Bomsel M, Tudor D, Drillet AS et al. Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges. Immunity 2011;34:269-80.
-
(2011)
Immunity
, vol.34
, pp. 269-280
-
-
Bomsel, M.1
Tudor, D.2
Drillet, A.S.3
-
99
-
-
74649084593
-
The ABC of clinical and experimental adjuvants-a brief overview
-
Brunner R, Jensen-Jarolim E, Pali-Schöll I. The ABC of clinical and experimental adjuvants-a brief overview. Immunol Lett 2010;128:29-35.
-
(2010)
Immunol Lett
, vol.128
, pp. 29-35
-
-
Brunner, R.1
Jensen-Jarolim, E.2
Pali-Schöll, I.3
-
100
-
-
84882823975
-
Long-term CD4(+) and CD8(+) T-cell responses induced in HIV-uninfected volunteers following intradermal or intramuscular administration of an HIV-lipopeptide vaccine (ANRS VAC16)
-
Launay O, Surenaud M, Desaint C et al. Long-term CD4(+) and CD8(+) T-cell responses induced in HIV-uninfected volunteers following intradermal or intramuscular administration of an HIV-lipopeptide vaccine (ANRS VAC16). Vaccine 2013;31:4406-15.
-
(2013)
Vaccine
, vol.31
, pp. 4406-4415
-
-
Launay, O.1
Surenaud, M.2
Desaint, C.3
-
101
-
-
84879833545
-
Characterization of humoral responses to soluble trimeric HIV gp140 from a clade A Ugandan field isolate
-
Visciano ML, Tagliamonte M, Stewart-Jones G et al. Characterization of humoral responses to soluble trimeric HIV gp140 from a clade A Ugandan field isolate. J Transl Med 2013;11:165.
-
(2013)
J Transl Med
, vol.11
, pp. 165
-
-
Visciano, M.L.1
Tagliamonte, M.2
Stewart-Jones, G.3
-
102
-
-
84883659521
-
Antibodies and their receptors: different potential roles in mucosal defense
-
Horton RE, Vidarsson G. Antibodies and their receptors: different potential roles in mucosal defense. Front Immunol 2013;4:200.
-
(2013)
Front Immunol
, vol.4
, pp. 200
-
-
Horton, R.E.1
Vidarsson, G.2
-
103
-
-
84875769446
-
Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes
-
Manrique M, Kozlowski PA, Cobo-Molinos A et al. Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes. J Virol 2013;87:4738-50.
-
(2013)
J Virol
, vol.87
, pp. 4738-4750
-
-
Manrique, M.1
Kozlowski, P.A.2
Cobo-Molinos, A.3
-
104
-
-
84874049583
-
Systemic vaccination induces clonally diverse SIV-specific CD8+ T-cell populations in systemic and mucosal compartments
-
Sircar P, Furr KL, Letvin NL. Systemic vaccination induces clonally diverse SIV-specific CD8+ T-cell populations in systemic and mucosal compartments. Mucosal Immunol 2013;6:93-103.
-
(2013)
Mucosal Immunol
, vol.6
, pp. 93-103
-
-
Sircar, P.1
Furr, K.L.2
Letvin, N.L.3
-
105
-
-
84883598341
-
Unique IL-13Rα2-based HIV-1 vaccine strategy to enhance mucosal immunity, CD8(+) T-cell avidity and protective immunity
-
Ranasinghe C, Trivedi S, Stambas J, Jackson RJ. Unique IL-13Rα2-based HIV-1 vaccine strategy to enhance mucosal immunity, CD8(+) T-cell avidity and protective immunity. Mucosal Immunol 2013;6:1068-80.
-
(2013)
Mucosal Immunol
, vol.6
, pp. 1068-1080
-
-
Ranasinghe, C.1
Trivedi, S.2
Stambas, J.3
Jackson, R.J.4
-
106
-
-
84874274760
-
Randomized phase I: safety, immunogenicity and mucosal antiviral activity in young healthy women vaccinated with HIV-1 Gp41 P1 peptide on virosomes
-
Leroux-Roels G, Maes C, Clement F et al. Randomized phase I: safety, immunogenicity and mucosal antiviral activity in young healthy women vaccinated with HIV-1 Gp41 P1 peptide on virosomes. PLoS ONE 2013;8:e55438.
-
(2013)
PLoS ONE
, vol.8
-
-
Leroux-Roels, G.1
Maes, C.2
Clement, F.3
|