Immunologic considerations for generating memory CD8 T cells through vaccination

Cellular Microbiology

Volumn 13, Issue 7, 2011, Pages 925-933

  Butler, Noah S ^a   Nolz, Jeffrey C ^a   Harty, John T ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; DENDRITIC CELL VACCINE; MICROSPHERE; POLYGLACTIN; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; VIRUS VACCINE;

ANTIBODY PRODUCTION; ANTIGEN PRESENTING CELL; CD8+ T LYMPHOCYTE; HUMAN; IMMUNOLOGICAL MEMORY; IMMUNOMODULATION; IMMUNOPHENOTYPING; MEMORY T LYMPHOCYTE; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REINFECTION; SHORT SURVEY; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; VACCINATION;

CD8-POSITIVE T-LYMPHOCYTES; HUMANS; IMMUNOLOGIC MEMORY; MODELS, BIOLOGICAL; VACCINATION; VACCINES;

EID: 79959198170     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2011.01594.x     Document Type: Short Survey

References (63)

1. Aichele, P., Unsoeld, H., Koschella, M., Schweier, O., Kalinke, U., and Vucikuja, S. (2006) CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion. J Immunol 176: 4525-4529.
2. Andre, F.E. (2003) Vaccinology: past achievements, present roadblocks and future promises. Vaccine 21: 593-595.
3. Araki, K., Turner, A.P., Shaffer, V.O., Gangappa, S., Keller, S.A., Bachmann, M.F., etal. (2009) mTOR regulates memory CD8 T-cell differentiation. Nature 460: 108-112.
4. Badovinac, V.P., Messingham, K.A., Hamilton, S.E., and Harty, J.T. (2003) Regulation of CD8+ T cells undergoing primary and secondary responses to infection in the same host. J Immunol 170: 4933-4942.
5. Badovinac, V.P., Messingham, K.A., Jabbari, A., Haring, J.S., and Harty, J.T. (2005) Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination. Nat Med 11: 748-756.
6. Barber, D.L., Wherry, E.J., and Ahmed, R. (2003) Cutting edge: rapid in vivo killing by memory CD8 T cells. J Immunol 171: 27-31.
7. Becker, T.C., Wherry, E.J., Boone, D., Murali-Krishna, K., Antia, R., Ma, A., and Ahmed, R. (2002) Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 195: 1541-1548.
8. Blattman, J.N., Antia, R., Sourdive, D.J., Wang, X., Kaech, S.M., Murali-Krishna, K., etal. (2002) Estimating the precursor frequency of naive antigen-specific CD8 T cells. J Exp Med 195: 657-664.
9. Butler, N.S., and Harty, J.T. (2010) The role of inflammation in the generation and maintenance of memory T cells. Adv Exp Med Biol 684: 42-56.
10. Chen, G., Shankar, P., Lange, C., Valdez, H., Skolnik, P.R., Wu, L., etal. (2001) CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection. Blood 98: 156-164.
11. Cho, B.K., Wang, C., Sugawa, S., Eisen, H.N., and Chen, J. (1999) Functional differences between memory and naive CD8 T cells. Proc Natl Acad Sci USA 96: 2976-2981.
12. Curtsinger, J.M., Johnson, C.M., and Mescher, M.F. (2003) CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine. J Immunol 171: 5165-5171.
13. Curtsinger, J.M., Valenzuela, J.O., Agarwal, P., Lins, D., and Mescher, M.F. (2005) Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation. J Immunol 174: 4465-4469.
14. Dustin, M.L. (2004) Stop and go traffic to tune T cell responses. Immunity 21: 305-314.
15. Gebhardt, T., Wakim, L.M., Eidsmo, L., Reading, P.C., Heath, W.R., and Carbone, F.R. (2009) Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nat Immunol 10: 524-530.
16. Good, M.F., and Doolan, D.L. (2010) Malaria vaccine design: immunological considerations. Immunity 33: 555-566.
17. Hand, T.W., Morre, M., and Kaech, S.M. (2007) Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection. Proc Natl Acad Sci USA 104: 11730-11735.
18. Haring, J.S., Badovinac, V.P., and Harty, J.T. (2006) Inflaming the CD8+ T cell response. Immunity 25: 19-29.
19. Haring, J.S., Jing, X., Bollenbacher-Reilley, J., Xue, H.H., Leonard, W.J., and Harty, J.T. (2008) Constitutive expression of IL-7 receptor alpha does not support increased expansion or prevent contraction of antigen-specific CD4 or CD8 T cells following Listeria monocytogenes infection. J Immunol 180: 2855-2862.
20. Harty, J.T., and Badovinac, V.P. (2008) Shaping and reshaping CD8+ T-cell memory. Nat Rev Immunol 8: 107-119.
21. Heath, W.R., Belz, G.T., Behrens, G.M., Smith, C.M., Forehan, S.P., Parish, I.A., etal. (2004) Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol Rev 199: 9-26.
22. Homann, D., Teyton, L., and Oldstone, M.B. (2001) Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory. Nat Med 7: 913-919.
23. Jabbari, A., and Harty, J.T. (2006) Secondary memory CD8+ T cells are more protective but slower to acquire a central-memory phenotype. J Exp Med 203: 919-932.
24. Jameson, S.C., and Masopust, D. (2009) Diversity in T cell memory: an embarrassment of riches. Immunity 31: 859-871.
25. Kaech, S.M., Hemby, S., Kersh, E., and Ahmed, R. (2002a) Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111: 837-851.
26. Kaech, S.M., Wherry, E.J., and Ahmed, R. (2002b) Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol 2: 251-262.
27. Kaech, S.M., Tan, J.T., Wherry, E.J., Konieczny, B.T., Surh, C.D., and Ahmed, R. (2003) Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 4: 1191-1198.
28. Kalia, V., Sarkar, S., Subramaniam, S., Haining, W.N., Smith, K.A., and Ahmed, R. (2010) Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity 32: 91-103.
29. Kaufmann, S.H. (2010) Future vaccination strategies against tuberculosis: thinking outside the box. Immunity 33: 567-577.
30. Kohlmeier, J.E., Cookenham, T., Roberts, A.D., Miller, S.C., and Woodland, D.L. (2010) Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge. Immunity 33: 96-105.
31. Kurts, C., Robinson, B.W., and Knolle, P.A. (2010) Cross-priming in health and disease. Nat Rev Immunol 10: 403-414.
32. Leignadier, J., Hardy, M.P., Cloutier, M., Rooney, J., and Labrecque, N. (2008) Memory T-lymphocyte survival does not require T-cell receptor expression. Proc Natl Acad Sci USA 105: 20440-20445.
33. McElrath, M.J., and Haynes, B.F. (2010) Induction of immunity to human immunodeficiency virus type-1 by vaccination. Immunity 33: 542-554.
34. Marzo, A.L., Yagita, H., and Lefrancois, L. (2007) Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells. J Immunol 179: 36-40.
35. Masopust, D., Vezys, V., Marzo, A.L., and Lefrancois, L. (2001) Preferential localization of effector memory cells in nonlymphoid tissue. Science 291: 2413-2417.
36. Masopust, D., Ha, S.J., Vezys, V., and Ahmed, R. (2006) Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. J Immunol 177: 831-839.
37. Masopust, D., Choo, D., Vezys, V., Wherry, E.J., Duraiswamy, J., Akondy, R., etal. (2010) Dynamic T cell migration program provides resident memory within intestinal epithelium. J Exp Med 207: 553-564.
38. Mempel, T.R., Henrickson, S.E., and Von Andrian, U.H. (2004) T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427: 154-159.
39. Mescher, M.F., Curtsinger, J.M., Agarwal, P., Casey, K.A., Gerner, M., Hammerbeck, C.D., etal. (2006) Signals required for programming effector and memory development by CD8+ T cells. Immunol Rev 211: 81-92.
40. Murali-Krishna, K., Lau, L.L., Sambhara, S., Lemonnier, F., Altman, J., and Ahmed, R. (1999) Persistence of memory CD8 T cells in MHC class I-deficient mice. Science 286: 1377-1381.
41. Obar, J.J., Khanna, K.M., and Lefrancois, L. (2008) Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. Immunity 28: 859-869.
42. Obar, J.J., Molloy, M.J., Jellison, E.R., Stoklasek, T.A., Zhang, W., Usherwood, E.J., and Lefrancois, L. (2010) CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses. Proc Natl Acad Sci USA 107: 193-198.
43. Pearce, E.L., and Shen, H. (2007) Generation of CD8 T cell memory is regulated by IL-12. J Immunol 179: 2074-2081.
44. Pearce, E.L., Walsh, M.C., Cejas, P.J., Harms, G.M., Shen, H., Wang, L.S., etal. (2009) Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 460: 103-107.
45. Pham, N.L., Badovinac, V.P., and Harty, J.T. (2009) A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation. J Immunol 183: 2337-2348.
46. Pham, N.L., Pewe, L.L., Fleenor, C.J., Langlois, R.A., Legge, K.L., Badovinac, V.P., and Harty, J.T. (2010) Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly. Proc Natl Acad Sci USA 107: 12198-12203.
47. Pipkin, M.E., Sacks, J.A., Cruz-Guilloty, F., Lichtenheld, M.G., Bevan, M.J., and Rao, A. (2010) Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32: 79-90.
48. Prlic, M., and Bevan, M.J. (2009) Immunology: a metabolic switch to memory. Nature 460: 41-42.
49. Sallusto, F., Lenig, D., Forster, R., Lipp, M., and Lanzavecchia, A. (1999) Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401: 708-712.
50. Sallusto, F., Lanzavecchia, A., Araki, K., and Ahmed, R. (2010) From vaccines to memory and back. Immunity 33: 451-463.
51. Schluns, K.S., and Lefrancois, L. (2003) Cytokine control of memory T-cell development and survival. Nat Rev Immunol 3: 269-279.
52. Schluns, K.S., Kieper, W.C., Jameson, S.C., and Lefrancois, L. (2000) Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 1: 426-432.
53. Schmidt, N.W., Podyminogin, R.L., Butler, N.S., Badovinac, V.P., Tucker, B.J., Bahjat, K.S., etal. (2008) Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria. Proc Natl Acad Sci USA 105: 14017-14022.
54. Seder, R.A., and Hill, A.V. (2000) Vaccines against intracellular infections requiring cellular immunity. Nature 406: 793-798.
55. Stemberger, C., Huster, K.M., Koffler, M., Anderl, F., Schiemann, M., Wagner, H., and Busch, D.H. (2007) A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets. Immunity 27: 985-997.
56. Thompson, L.J., Kolumam, G.A., Thomas, S., and Murali-Krishna, K. (2006) Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation. J Immunol 177: 1746-1754.
57. Wherry, E.J., Puorro, K.A., Porgador, A., and Eisenlohr, L.C. (1999) The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained. J Immunol 163: 3735-3745.
58. Wherry, E.J., Teichgraber, V., Becker, T.C., Masopust, D., Kaech, S.M., Antia, R., etal. (2003) Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol 4: 225-234.
59. Williams, M.A., Tyznik, A.J., and Bevan, M.J. (2006) Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature 441: 890-893.
60. Wirth, T.C., Xue, H.H., Rai, D., Sabel, J.T., Bair, T., Harty, J.T., and Badovinac, V.P. (2010) Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation. Immunity 33: 128-140.
61. Woodland, D.L. (2004) Jump-starting the immune system: prime-boosting comes of age. Trends Immunol 25: 98-104.
62. Woodland, D.L., and Kohlmeier, J.E. (2009) Migration, maintenance and recall of memory T cells in peripheral tissues. Nat Rev Immunol 9: 153-161.
63. Zehn, D., Lee, S.Y., and Bevan, M.J. (2009) Complete but curtailed T-cell response to very low-affinity antigen. Nature 458: 211-214.