-
1
-
-
84876806808
-
RNA-binding proteins in Mendelian disease
-
Castello A, Fischer B, Hentze MW, Preiss T. RNA-binding proteins in Mendelian disease. Trends Genet 2013, 29:318-327.
-
(2013)
Trends Genet
, vol.29
, pp. 318-327
-
-
Castello, A.1
Fischer, B.2
Hentze, M.W.3
Preiss, T.4
-
2
-
-
84877926794
-
Multi-disciplinary methods to define RNA-protein interactions and regulatory networks
-
Ascano M, Gerstberger S, Tuschl T. Multi-disciplinary methods to define RNA-protein interactions and regulatory networks. Curr Opin Genet Dev 2013, 23:20-28.
-
(2013)
Curr Opin Genet Dev
, vol.23
, pp. 20-28
-
-
Ascano, M.1
Gerstberger, S.2
Tuschl, T.3
-
3
-
-
24344452361
-
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain
-
McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol 2005, 5:14.
-
(2005)
BMC Dev Biol
, vol.5
, pp. 14
-
-
McKee, A.E.1
Minet, E.2
Stern, C.3
Riahi, S.4
Stiles, C.D.5
Silver, P.A.6
-
4
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, Kingsmore SF, Schroth GP, Burge CB. Alternative isoform regulation in human tissue transcriptomes. Nature 2008, 456:470-476.
-
(2008)
Nature
, vol.456
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
Khrebtukova, I.4
Zhang, L.5
Mayr, C.6
Kingsmore, S.F.7
Schroth, G.P.8
Burge, C.B.9
-
5
-
-
84862151933
-
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
-
King OD, Gitler AD, Shorter J. The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. Brain Res 2012, 1462:61-80.
-
(2012)
Brain Res
, vol.1462
, pp. 61-80
-
-
King, O.D.1
Gitler, A.D.2
Shorter, J.3
-
6
-
-
84873521914
-
RRM-RNA recognition: NMR or crystallography... and new findings
-
Daubner GM, Clery A, Allain FH. RRM-RNA recognition: NMR or crystallography... and new findings. Curr Opin Struct Biol 2013, 23:100-108.
-
(2013)
Curr Opin Struct Biol
, vol.23
, pp. 100-108
-
-
Daubner, G.M.1
Clery, A.2
Allain, F.H.3
-
7
-
-
43549124851
-
Structure and function of KH domains
-
Valverde R, Edwards L, Regan L. Structure and function of KH domains. FEBS J 2008, 275:2712-2726.
-
(2008)
FEBS J
, vol.275
, pp. 2712-2726
-
-
Valverde, R.1
Edwards, L.2
Regan, L.3
-
8
-
-
84878840917
-
Defining the RGG/RG motif
-
Thandapani P, O'Connor TR, Bailey TL, Richard S. Defining the RGG/RG motif. Mol Cell 2013, 50:613-623.
-
(2013)
Mol Cell
, vol.50
, pp. 613-623
-
-
Thandapani, P.1
O'Connor, T.R.2
Bailey, T.L.3
Richard, S.4
-
9
-
-
13844297911
-
Zinc finger proteins: getting a grip on RNA
-
Brown RS. Zinc finger proteins: getting a grip on RNA. Curr Opin Struct Biol 2005, 15:94-98.
-
(2005)
Curr Opin Struct Biol
, vol.15
, pp. 94-98
-
-
Brown, R.S.1
-
10
-
-
82955236089
-
RNA targets of wild-type and mutant FET family proteins
-
Hoell JI, Larsson E, Runge S, Nusbaum JD, Duggimpudi S, Farazi TA, Hafner M, Borkhardt A, Sander C, Tuschl T. RNA targets of wild-type and mutant FET family proteins. Nat Struct Mol Biol 2011, 18:1428-1431.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1428-1431
-
-
Hoell, J.I.1
Larsson, E.2
Runge, S.3
Nusbaum, J.D.4
Duggimpudi, S.5
Farazi, T.A.6
Hafner, M.7
Borkhardt, A.8
Sander, C.9
Tuschl, T.10
-
11
-
-
33644858553
-
The Muscleblind family of proteins: an emerging class of regulators of developmentally programmed alternative splicing
-
Pascual M, Vicente M, Monferrer L, Artero R. The Muscleblind family of proteins: an emerging class of regulators of developmentally programmed alternative splicing. Differentiation 2006, 74:65-80.
-
(2006)
Differentiation
, vol.74
, pp. 65-80
-
-
Pascual, M.1
Vicente, M.2
Monferrer, L.3
Artero, R.4
-
12
-
-
76549101962
-
Eukaryotic cold shock domain proteins: highly versatile regulators of gene expression
-
Mihailovich M, Militti C, Gabaldon T, Gebauer F. Eukaryotic cold shock domain proteins: highly versatile regulators of gene expression. Bioessays 2010, 32:109-118.
-
(2010)
Bioessays
, vol.32
, pp. 109-118
-
-
Mihailovich, M.1
Militti, C.2
Gabaldon, T.3
Gebauer, F.4
-
13
-
-
84879408529
-
Alternative cleavage and polyadenylation: extent, regulation and function
-
Elkon R, Ugalde AP, Agami R. Alternative cleavage and polyadenylation: extent, regulation and function. Nat Rev Genet 2013, 14:496-506.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 496-506
-
-
Elkon, R.1
Ugalde, A.P.2
Agami, R.3
-
14
-
-
34347384211
-
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons
-
Boutz PL, Stoilov P, Li Q, Lin CH, Chawla G, Ostrow K, Shiue L, Ares M Jr, Black DL. A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev 2007, 21:1636-1652.
-
(2007)
Genes Dev
, vol.21
, pp. 1636-1652
-
-
Boutz, P.L.1
Stoilov, P.2
Li, Q.3
Lin, C.H.4
Chawla, G.5
Ostrow, K.6
Shiue, L.7
Ares Jr, M.8
Black, D.L.9
-
15
-
-
77954838957
-
Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls
-
Zhang C, Frias MA, Mele A, Ruggiu M, Eom T, Marney CB, Wang H, Licatalosi DD, Fak JJ, Darnell RB. Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls. Science 2010, 329:439-443.
-
(2010)
Science
, vol.329
, pp. 439-443
-
-
Zhang, C.1
Frias, M.A.2
Mele, A.3
Ruggiu, M.4
Eom, T.5
Marney, C.B.6
Wang, H.7
Licatalosi, D.D.8
Fak, J.J.9
Darnell, R.B.10
-
16
-
-
84866390941
-
RBFOX1 regulates both splicing and transcriptional networks in human neuronal development
-
Fogel BL, Wexler E, Wahnich A, Friedrich T, Vijayendran C, Gao F, Parikshak N, Konopka G, Geschwind DH. RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. Hum Mol Genet 2012, 21:4171-4186.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4171-4186
-
-
Fogel, B.L.1
Wexler, E.2
Wahnich, A.3
Friedrich, T.4
Vijayendran, C.5
Gao, F.6
Parikshak, N.7
Konopka, G.8
Geschwind, D.H.9
-
17
-
-
84455200617
-
SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1
-
Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S, Scheiffele P. SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1. Cell 2011, 147:1601-1614.
-
(2011)
Cell
, vol.147
, pp. 1601-1614
-
-
Iijima, T.1
Wu, K.2
Witte, H.3
Hanno-Iijima, Y.4
Glatter, T.5
Richard, S.6
Scheiffele, P.7
-
18
-
-
84878020681
-
A matter of balance: role of neurexin and neuroligin at the synapse
-
Bang ML, Owczarek S. A matter of balance: role of neurexin and neuroligin at the synapse. Neurochem Res 2013, 38:1174-1189.
-
(2013)
Neurochem Res
, vol.38
, pp. 1174-1189
-
-
Bang, M.L.1
Owczarek, S.2
-
19
-
-
84859355676
-
Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation
-
Mansfield KD, Keene JD. Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation. Nucleic Acids Res 2012, 40:2734-2746.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 2734-2746
-
-
Mansfield, K.D.1
Keene, J.D.2
-
20
-
-
84877922071
-
Mechanisms coordinating ELAV/Hu mRNA regulons
-
Simone LE, Keene JD. Mechanisms coordinating ELAV/Hu mRNA regulons. Curr Opin Genet Dev 2013, 23:35-43.
-
(2013)
Curr Opin Genet Dev
, vol.23
, pp. 35-43
-
-
Simone, L.E.1
Keene, J.D.2
-
21
-
-
84866505114
-
Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability
-
Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, et al. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron 2012, 75:1067-1080.
-
(2012)
Neuron
, vol.75
, pp. 1067-1080
-
-
Ince-Dunn, G.1
Okano, H.J.2
Jensen, K.B.3
Park, W.Y.4
Zhong, R.5
Ule, J.6
Mele, A.7
Fak, J.J.8
Yang, C.9
Zhang, C.10
-
22
-
-
84873717509
-
Taking a cellular road-trip: mRNA transport and anchoring
-
Pratt CA, Mowry KL. Taking a cellular road-trip: mRNA transport and anchoring. Curr Opin Cell Biol 2013, 25:99-106.
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 99-106
-
-
Pratt, C.A.1
Mowry, K.L.2
-
23
-
-
80052235798
-
Mechanisms of dendritic mRNA transport and its role in synaptic tagging
-
Doyle M, Kiebler MA. Mechanisms of dendritic mRNA transport and its role in synaptic tagging. EMBO J 2011, 30:3540-3552.
-
(2011)
EMBO J
, vol.30
, pp. 3540-3552
-
-
Doyle, M.1
Kiebler, M.A.2
-
24
-
-
84871504054
-
Translational control at the synapse: role of RNA regulators
-
Iacoangeli A, Tiedge H. Translational control at the synapse: role of RNA regulators. Trends Biochem Sci 2013, 38:47-55.
-
(2013)
Trends Biochem Sci
, vol.38
, pp. 47-55
-
-
Iacoangeli, A.1
Tiedge, H.2
-
25
-
-
84858625887
-
Neuronal mRNAs travel singly into dendrites
-
Batish M, van den Bogaard P, Kramer FR, Tyagi S. Neuronal mRNAs travel singly into dendrites. Proc Natl Acad Sci U S A 2012, 109:4645-4650.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 4645-4650
-
-
Batish, M.1
van den Bogaard, P.2
Kramer, F.R.3
Tyagi, S.4
-
26
-
-
0029808910
-
Translocation of RNA granules in living neurons
-
Knowles RB, Sabry JH, Martone ME, Deerinck TJ, Ellisman MH, Bassell GJ, Kosik KS. Translocation of RNA granules in living neurons. J Neurosci 1996, 16:7812-7820.
-
(1996)
J Neurosci
, vol.16
, pp. 7812-7820
-
-
Knowles, R.B.1
Sabry, J.H.2
Martone, M.E.3
Deerinck, T.J.4
Ellisman, M.H.5
Bassell, G.J.6
Kosik, K.S.7
-
27
-
-
0037421207
-
Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment
-
Farina KL, Huttelmaier S, Musunuru K, Darnell R, Singer RH. Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. J Cell Biol 2003, 160:77-87.
-
(2003)
J Cell Biol
, vol.160
, pp. 77-87
-
-
Farina, K.L.1
Huttelmaier, S.2
Musunuru, K.3
Darnell, R.4
Singer, R.H.5
-
28
-
-
79955734697
-
Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons
-
Perycz M, Urbanska AS, Krawczyk PS, Parobczak K, Jaworski J. Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons. J Neurosci 2011, 31:5271-5285.
-
(2011)
J Neurosci
, vol.31
, pp. 5271-5285
-
-
Perycz, M.1
Urbanska, A.S.2
Krawczyk, P.S.3
Parobczak, K.4
Jaworski, J.5
-
30
-
-
0034109216
-
Molecular insights into mRNA transport and local translation in the mammalian nervous system
-
Kiebler MA, DesGroseillers L. Molecular insights into mRNA transport and local translation in the mammalian nervous system. Neuron 2000, 25:19-28.
-
(2000)
Neuron
, vol.25
, pp. 19-28
-
-
Kiebler, M.A.1
DesGroseillers, L.2
-
31
-
-
33845445765
-
Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies
-
Barbee SA, Estes PS, Cziko AM, Hillebrand J, Luedeman RA, Coller JM, Johnson N, Howlett IC, Geng C, Ueda R, et al. Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron 2006, 52:997-1009.
-
(2006)
Neuron
, vol.52
, pp. 997-1009
-
-
Barbee, S.A.1
Estes, P.S.2
Cziko, A.M.3
Hillebrand, J.4
Luedeman, R.A.5
Coller, J.M.6
Johnson, N.7
Howlett, I.C.8
Geng, C.9
Ueda, R.10
-
32
-
-
79960779323
-
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
-
Darnell JC, Van Driesche SJ, Zhang C, Hung KY, Mele A, Fraser CE, Stone EF, Chen C, Fak JJ, Chi SW, et al. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell 2011, 146:247-261.
-
(2011)
Cell
, vol.146
, pp. 247-261
-
-
Darnell, J.C.1
Van Driesche, S.J.2
Zhang, C.3
Hung, K.Y.4
Mele, A.5
Fraser, C.E.6
Stone, E.F.7
Chen, C.8
Fak, J.J.9
Chi, S.W.10
-
33
-
-
79151471434
-
PUF proteins: repression, activation and mRNA localization
-
Quenault T, Lithgow T, Traven A. PUF proteins: repression, activation and mRNA localization. Trends Cell Biol 2011, 21:104-112.
-
(2011)
Trends Cell Biol
, vol.21
, pp. 104-112
-
-
Quenault, T.1
Lithgow, T.2
Traven, A.3
-
34
-
-
59649126241
-
The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits
-
Christie SB, Akins MR, Schwob JE, Fallon JR. The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits. J Neurosci 2009, 29:1514-1524.
-
(2009)
J Neurosci
, vol.29
, pp. 1514-1524
-
-
Christie, S.B.1
Akins, M.R.2
Schwob, J.E.3
Fallon, J.R.4
-
35
-
-
84888788450
-
The FMRP regulon: from targets to disease convergence
-
Fernandez E, Rajan N, Bagni C. The FMRP regulon: from targets to disease convergence. Front Neurosci 2013, 7:191.
-
(2013)
Front Neurosci
, vol.7
, pp. 191
-
-
Fernandez, E.1
Rajan, N.2
Bagni, C.3
-
36
-
-
84886953546
-
The translation of translational control by FMRP: therapeutic targets for FXS
-
Darnell JC, Klann E. The translation of translational control by FMRP: therapeutic targets for FXS. Nat Neurosci 2013, 16:1530-1536.
-
(2013)
Nat Neurosci
, vol.16
, pp. 1530-1536
-
-
Darnell, J.C.1
Klann, E.2
-
37
-
-
0035923735
-
Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation
-
Krichevsky AM, Kosik KS. Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron 2001, 32:683-696.
-
(2001)
Neuron
, vol.32
, pp. 683-696
-
-
Krichevsky, A.M.1
Kosik, K.S.2
-
38
-
-
0035829728
-
A role for a rat homolog of staufen in the transport of RNA to neuronal dendrites
-
Tang SJ, Meulemans D, Vazquez L, Colaco N, Schuman E. A role for a rat homolog of staufen in the transport of RNA to neuronal dendrites. Neuron 2001, 32:463-475.
-
(2001)
Neuron
, vol.32
, pp. 463-475
-
-
Tang, S.J.1
Meulemans, D.2
Vazquez, L.3
Colaco, N.4
Schuman, E.5
-
39
-
-
55849118831
-
A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis
-
Vessey JP, Macchi P, Stein JM, Mikl M, Hawker KN, Vogelsang P, Wieczorek K, Vendra G, Riefler J, Tubing F, et al. A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis. Proc Natl Acad Sci U S A 2008, 105:16374-16379.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16374-16379
-
-
Vessey, J.P.1
Macchi, P.2
Stein, J.M.3
Mikl, M.4
Hawker, K.N.5
Vogelsang, P.6
Wieczorek, K.7
Vendra, G.8
Riefler, J.9
Tubing, F.10
-
40
-
-
84863307704
-
Neurodegeneration-associated TDP-43 interacts with fragile X mental retardation protein (FMRP)/Staufen (STAU1) and regulates SIRT1 expression in neuronal cells
-
Yu Z, Fan D, Gui B, Shi L, Xuan C, Shan L, Wang Q, Shang Y, Wang Y. Neurodegeneration-associated TDP-43 interacts with fragile X mental retardation protein (FMRP)/Staufen (STAU1) and regulates SIRT1 expression in neuronal cells. J Biol Chem 2012, 287:22560-22572.
-
(2012)
J Biol Chem
, vol.287
, pp. 22560-22572
-
-
Yu, Z.1
Fan, D.2
Gui, B.3
Shi, L.4
Xuan, C.5
Shan, L.6
Wang, Q.7
Shang, Y.8
Wang, Y.9
-
41
-
-
12944327374
-
Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay
-
Kim YK, Furic L, Desgroseillers L, Maquat LE. Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. Cell 2005, 120:195-208.
-
(2005)
Cell
, vol.120
, pp. 195-208
-
-
Kim, Y.K.1
Furic, L.2
Desgroseillers, L.3
Maquat, L.E.4
-
42
-
-
84867850145
-
NMD: a multifaceted response to premature translational termination
-
Kervestin S, Jacobson A. NMD: a multifaceted response to premature translational termination. Nat Rev Mol Cell Biol 2012, 13:700-712.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 700-712
-
-
Kervestin, S.1
Jacobson, A.2
-
43
-
-
84878888946
-
Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay
-
Colak D, Ji SJ, Porse BT, Jaffrey SR. Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay. Cell 2013, 153:1252-1265.
-
(2013)
Cell
, vol.153
, pp. 1252-1265
-
-
Colak, D.1
Ji, S.J.2
Porse, B.T.3
Jaffrey, S.R.4
-
44
-
-
84875441083
-
The changing scene of amyotrophic lateral sclerosis
-
Robberecht W, Philips T. The changing scene of amyotrophic lateral sclerosis. Nat Rev Neurosci 2013, 14:248-264.
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 248-264
-
-
Robberecht, W.1
Philips, T.2
-
46
-
-
84887891531
-
The intriguing case of motor neuron disease: ALS and SMA come closer
-
Achsel T, Barabino S, Cozzolino M, Carri MT. The intriguing case of motor neuron disease: ALS and SMA come closer. Biochem Soc Trans 2013, 41:1593-1597.
-
(2013)
Biochem Soc Trans
, vol.41
, pp. 1593-1597
-
-
Achsel, T.1
Barabino, S.2
Cozzolino, M.3
Carri, M.T.4
-
47
-
-
27844514227
-
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
-
Buratti E, Brindisi A, Giombi M, Tisminetzky S, Ayala YM, Baralle FE. TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J Biol Chem 2005, 280:37572-37584.
-
(2005)
J Biol Chem
, vol.280
, pp. 37572-37584
-
-
Buratti, E.1
Brindisi, A.2
Giombi, M.3
Tisminetzky, S.4
Ayala, Y.M.5
Baralle, F.E.6
-
48
-
-
34547697173
-
RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS
-
Sofola OA, Jin P, Qin Y, Duan R, Liu H, de Haro M, Nelson DL, Botas J. RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. Neuron 2007, 55:565-571.
-
(2007)
Neuron
, vol.55
, pp. 565-571
-
-
Sofola, O.A.1
Jin, P.2
Qin, Y.3
Duan, R.4
Liu, H.5
de Haro, M.6
Nelson, D.L.7
Botas, J.8
-
49
-
-
77953890823
-
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
-
Lagier-Tourenne C, Polymenidou M, Cleveland DW. TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum Mol Genet 2010, 19:R46-64.
-
(2010)
Hum Mol Genet
, vol.19
-
-
Lagier-Tourenne, C.1
Polymenidou, M.2
Cleveland, D.W.3
-
50
-
-
75949105684
-
TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis
-
Giordana MT, Piccinini M, Grifoni S, De Marco G, Vercellino M, Magistrello M, Pellerino A, Buccinna B, Lupino E, Rinaudo MT. TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis. Brain Pathol 2010, 20:351-360.
-
(2010)
Brain Pathol
, vol.20
, pp. 351-360
-
-
Giordana, M.T.1
Piccinini, M.2
Grifoni, S.3
De Marco, G.4
Vercellino, M.5
Magistrello, M.6
Pellerino, A.7
Buccinna, B.8
Lupino, E.9
Rinaudo, M.T.10
-
51
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, Link CD, Lin WL, Tong J, Castanedes-Casey M, Ash P, et al. Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc Natl Acad Sci U S A 2009, 106:7607-7612.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
Gendron, T.F.4
Roettges, P.5
Link, C.D.6
Lin, W.L.7
Tong, J.8
Castanedes-Casey, M.9
Ash, P.10
-
52
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski TJ Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009, 323:1205-1208.
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski Jr, T.J.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
Davis, A.7
Gilchrist, J.8
Kasarskis, E.J.9
Munsat, T.10
-
53
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Vance C, Rogelj B, Hortobagyi T, De Vos KJ, Nishimura AL, Sreedharan J, Hu X, Smith B, Ruddy D, Wright P, et al. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 2009, 323:1208-1211.
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
De Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
Hu, X.7
Smith, B.8
Ruddy, D.9
Wright, P.10
-
54
-
-
77449136874
-
The TET family of proteins: functions and roles in disease
-
Tan AY, Manley JL. The TET family of proteins: functions and roles in disease. J Mol Cell Biol 2009, 1:82-92.
-
(2009)
J Mol Cell Biol
, vol.1
, pp. 82-92
-
-
Tan, A.Y.1
Manley, J.L.2
-
55
-
-
84884821327
-
Fused in sarcoma (FUS): An oncogene goes awry in neurodegeneration
-
Dormann D, Haass C. Fused in sarcoma (FUS): An oncogene goes awry in neurodegeneration. Mol Cell Neurosci 2013, 56:475-486.
-
(2013)
Mol Cell Neurosci
, vol.56
, pp. 475-486
-
-
Dormann, D.1
Haass, C.2
-
56
-
-
84868152371
-
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
-
Lagier-Tourenne C, Polymenidou M, Hutt KR, Vu AQ, Baughn M, Huelga SC, Clutario KM, Ling SC, Liang TY, Mazur C, et al. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nat Neurosci 2012, 15:1488-1497.
-
(2012)
Nat Neurosci
, vol.15
, pp. 1488-1497
-
-
Lagier-Tourenne, C.1
Polymenidou, M.2
Hutt, K.R.3
Vu, A.Q.4
Baughn, M.5
Huelga, S.C.6
Clutario, K.M.7
Ling, S.C.8
Liang, T.Y.9
Mazur, C.10
-
57
-
-
84868153116
-
FUS-SMN protein interactions link the motor neuron diseases ALS and SMA
-
Yamazaki T, Chen S, Yu Y, Yan B, Haertlein TC, Carrasco MA, Tapia JC, Zhai B, Das R, Lalancette-Hebert M, et al. FUS-SMN protein interactions link the motor neuron diseases ALS and SMA. Cell Rep 2012, 2:799-806.
-
(2012)
Cell Rep
, vol.2
, pp. 799-806
-
-
Yamazaki, T.1
Chen, S.2
Yu, Y.3
Yan, B.4
Haertlein, T.C.5
Carrasco, M.A.6
Tapia, J.C.7
Zhai, B.8
Das, R.9
Lalancette-Hebert, M.10
-
58
-
-
84877590417
-
Mislocalised FUS mutants stall spliceosomal snRNPs in the cytoplasm
-
Gerbino V, Carri MT, Cozzolino M, Achsel T. Mislocalised FUS mutants stall spliceosomal snRNPs in the cytoplasm. Neurobiol Dis 2013, 55:120-128.
-
(2013)
Neurobiol Dis
, vol.55
, pp. 120-128
-
-
Gerbino, V.1
Carri, M.T.2
Cozzolino, M.3
Achsel, T.4
-
59
-
-
84873314088
-
Spliceosome integrity is defective in the motor neuron diseases ALS and SMA
-
Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H, Murayama S, et al. Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med 2013, 5:221-234.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 221-234
-
-
Tsuiji, H.1
Iguchi, Y.2
Furuya, A.3
Kataoka, A.4
Hatsuta, H.5
Atsuta, N.6
Tanaka, F.7
Hashizume, Y.8
Akatsu, H.9
Murayama, S.10
-
60
-
-
84881518613
-
Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis
-
Ishihara T, Ariizumi Y, Shiga A, Kato T, Tan CF, Sato T, Miki Y, Yokoo M, Fujino T, Koyama A, et al. Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis. Hum Mol Genet 2013, 22:4136-4147.
-
(2013)
Hum Mol Genet
, vol.22
, pp. 4136-4147
-
-
Ishihara, T.1
Ariizumi, Y.2
Shiga, A.3
Kato, T.4
Tan, C.F.5
Sato, T.6
Miki, Y.7
Yokoo, M.8
Fujino, T.9
Koyama, A.10
-
61
-
-
8544283791
-
The survival motor neuron protein in spinal muscular atrophy
-
Coovert DD, Le TT, McAndrew PE, Strasswimmer J, Crawford TO, Mendell JR, Coulson SE, Androphy EJ, Prior TW, Burghes AH. The survival motor neuron protein in spinal muscular atrophy. Hum Mol Genet 1997, 6:1205-1214.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1205-1214
-
-
Coovert, D.D.1
Le, T.T.2
McAndrew, P.E.3
Strasswimmer, J.4
Crawford, T.O.5
Mendell, J.R.6
Coulson, S.E.7
Androphy, E.J.8
Prior, T.W.9
Burghes, A.H.10
-
62
-
-
84875605133
-
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
-
Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, et al. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature 2013, 495:467-473.
-
(2013)
Nature
, vol.495
, pp. 467-473
-
-
Kim, H.J.1
Kim, N.C.2
Wang, Y.D.3
Scarborough, E.A.4
Moore, J.5
Diaz, Z.6
MacLea, K.S.7
Freibaum, B.8
Li, S.9
Molliex, A.10
-
63
-
-
84887043259
-
Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review
-
Vanderweyde T, Youmans K, Liu-Yesucevitz L, Wolozin B. Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review. Gerontology 2013, 59:524-533.
-
(2013)
Gerontology
, vol.59
, pp. 524-533
-
-
Vanderweyde, T.1
Youmans, K.2
Liu-Yesucevitz, L.3
Wolozin, B.4
-
64
-
-
84871718500
-
Spinal muscular atrophy: going beyond the motor neuron
-
Hamilton G, Gillingwater TH. Spinal muscular atrophy: going beyond the motor neuron. Trends Mol Med 2013, 19:40-50.
-
(2013)
Trends Mol Med
, vol.19
, pp. 40-50
-
-
Hamilton, G.1
Gillingwater, T.H.2
-
65
-
-
84862145991
-
Spinal muscular atrophy: the role of SMN in axonal mRNA regulation
-
Fallini C, Bassell GJ, Rossoll W. Spinal muscular atrophy: the role of SMN in axonal mRNA regulation. Brain Res 2012, 1462:81-92.
-
(2012)
Brain Res
, vol.1462
, pp. 81-92
-
-
Fallini, C.1
Bassell, G.J.2
Rossoll, W.3
-
66
-
-
84155167265
-
Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
-
Lee EB, Lee VM, Trojanowski JQ. Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration. Nat Rev Neurosci 2012, 13:38-50.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 38-50
-
-
Lee, E.B.1
Lee, V.M.2
Trojanowski, J.Q.3
-
67
-
-
60849103086
-
hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions
-
Fukuda T, Naiki T, Saito M, Irie K. hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions. Genes Cells 2009, 14:113-128.
-
(2009)
Genes Cells
, vol.14
, pp. 113-128
-
-
Fukuda, T.1
Naiki, T.2
Saito, M.3
Irie, K.4
-
68
-
-
84878964968
-
Stem cells: regulation by alternative splicing
-
Aaronson Y, Meshorer E. Stem cells: regulation by alternative splicing. Nature 2013, 498:176-177.
-
(2013)
Nature
, vol.498
, pp. 176-177
-
-
Aaronson, Y.1
Meshorer, E.2
-
69
-
-
77949775195
-
Repeat expansion disease: progress and puzzles in disease pathogenesis
-
La Spada AR, Taylor JP. Repeat expansion disease: progress and puzzles in disease pathogenesis. Nat Rev Genet 2010, 11:247-258.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 247-258
-
-
La Spada, A.R.1
Taylor, J.P.2
-
70
-
-
77954171034
-
Inactivation of hnRNP K by expanded intronic AUUCU repeat induces apoptosis via translocation of PKCdelta to mitochondria in spinocerebellar ataxia 10
-
White MC, Gao R, Xu W, Mandal SM, Lim JG, Hazra TK, Wakamiya M, Edwards SF, Raskin S, Teive HA, et al. Inactivation of hnRNP K by expanded intronic AUUCU repeat induces apoptosis via translocation of PKCdelta to mitochondria in spinocerebellar ataxia 10. PLoS Genet 2010, 6:e1000984.
-
(2010)
PLoS Genet
, vol.6
-
-
White, M.C.1
Gao, R.2
Xu, W.3
Mandal, S.M.4
Lim, J.G.5
Hazra, T.K.6
Wakamiya, M.7
Edwards, S.F.8
Raskin, S.9
Teive, H.A.10
-
71
-
-
71849083831
-
Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n
-
Sato N, Amino T, Kobayashi K, Asakawa S, Ishiguro T, Tsunemi T, Takahashi M, Matsuura T, Flanigan KM, Iwasaki S, et al. Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n. Am J Hum Genet 2009, 85:544-557.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 544-557
-
-
Sato, N.1
Amino, T.2
Kobayashi, K.3
Asakawa, S.4
Ishiguro, T.5
Tsunemi, T.6
Takahashi, M.7
Matsuura, T.8
Flanigan, K.M.9
Iwasaki, S.10
-
72
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
Renton AE, Majounie E, Waite A, Simon-Sanchez J, Rollinson S, Gibbs JR, Schymick JC, Laaksovirta H, van Swieten JC, Myllykangas L, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011, 72:257-268.
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
Simon-Sanchez, J.4
Rollinson, S.5
Gibbs, J.R.6
Schymick, J.C.7
Laaksovirta, H.8
van Swieten, J.C.9
Myllykangas, L.10
-
73
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, Baker M, Rutherford NJ, Nicholson AM, Finch NA, Flynn H, Adamson J, et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011, 72:245-256.
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
DeJesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
Boxer, A.L.4
Baker, M.5
Rutherford, N.J.6
Nicholson, A.M.7
Finch, N.A.8
Flynn, H.9
Adamson, J.10
-
74
-
-
84858622829
-
Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
-
Majounie E, Renton AE, Mok K, Dopper EG, Waite A, Rollinson S, Chio A, Restagno G, Nicolaou N, Simon-Sanchez J, et al. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. Lancet Neurol 2012, 11:323-330.
-
(2012)
Lancet Neurol
, vol.11
, pp. 323-330
-
-
Majounie, E.1
Renton, A.E.2
Mok, K.3
Dopper, E.G.4
Waite, A.5
Rollinson, S.6
Chio, A.7
Restagno, G.8
Nicolaou, N.9
Simon-Sanchez, J.10
-
75
-
-
77956850818
-
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
-
Mackenzie IR, Rademakers R, Neumann M. TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol 2010, 9:995-1007.
-
(2010)
Lancet Neurol
, vol.9
, pp. 995-1007
-
-
Mackenzie, I.R.1
Rademakers, R.2
Neumann, M.3
-
76
-
-
80052716635
-
Cellular toxicity of expanded RNA repeats: focus on RNA foci
-
Wojciechowska M, Krzyzosiak WJ. Cellular toxicity of expanded RNA repeats: focus on RNA foci. Hum Mol Genet 2011, 20:3811-3821.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3811-3821
-
-
Wojciechowska, M.1
Krzyzosiak, W.J.2
-
77
-
-
84881024167
-
Current insights into the C9orf72 repeat expansion diseases of the FTLD/ALS spectrum
-
Cruts M, Gijselinck I, Van Langenhove T, van der Zee J, Van Broeckhoven C. Current insights into the C9orf72 repeat expansion diseases of the FTLD/ALS spectrum. Trends Neurosci 2013, 36:450-459.
-
(2013)
Trends Neurosci
, vol.36
, pp. 450-459
-
-
Cruts, M.1
Gijselinck, I.2
Van Langenhove, T.3
van der Zee, J.4
Van Broeckhoven, C.5
-
78
-
-
70149112363
-
RNA gain-of-function in spinocerebellar ataxia type 8
-
Daughters RS, Tuttle DL, Gao W, Ikeda Y, Moseley ML, Ebner TJ, Swanson MS, Ranum LP. RNA gain-of-function in spinocerebellar ataxia type 8. PLoS Genet 2009, 5:e1000600.
-
(2009)
PLoS Genet
, vol.5
-
-
Daughters, R.S.1
Tuttle, D.L.2
Gao, W.3
Ikeda, Y.4
Moseley, M.L.5
Ebner, T.J.6
Swanson, M.S.7
Ranum, L.P.8
-
79
-
-
0142091175
-
SCA8 repeat expansion coexists with SCA1--not only with SCA6
-
Sulek A, Hoffman-Zacharska D, Zdzienicka E, Zaremba J. SCA8 repeat expansion coexists with SCA1--not only with SCA6. Am J Hum Genet 2003, 73:972-974.
-
(2003)
Am J Hum Genet
, vol.73
, pp. 972-974
-
-
Sulek, A.1
Hoffman-Zacharska, D.2
Zdzienicka, E.3
Zaremba, J.4
-
80
-
-
10744231577
-
Genetic testing in spinocerebellar ataxia in Taiwan: expansions of trinucleotide repeats in SCA8 and SCA17 are associated with typical Parkinson's disease
-
Wu YR, Lin HY, Chen CM, Gwinn-Hardy K, Ro LS, Wang YC, Li SH, Hwang JC, Fang K, Hsieh-Li HM, et al. Genetic testing in spinocerebellar ataxia in Taiwan: expansions of trinucleotide repeats in SCA8 and SCA17 are associated with typical Parkinson's disease. Clin Genet 2004, 65:209-214.
-
(2004)
Clin Genet
, vol.65
, pp. 209-214
-
-
Wu, Y.R.1
Lin, H.Y.2
Chen, C.M.3
Gwinn-Hardy, K.4
Ro, L.S.5
Wang, Y.C.6
Li, S.H.7
Hwang, J.C.8
Fang, K.9
Hsieh-Li, H.M.10
-
81
-
-
84886235508
-
Fragile X syndrome: from protein function to therapy
-
Bagni C, Oostra BA. Fragile X syndrome: from protein function to therapy. Am J Med Genet A 2013, 161:2809-2821.
-
(2013)
Am J Med Genet A
, vol.161
, pp. 2809-2821
-
-
Bagni, C.1
Oostra, B.A.2
-
82
-
-
30344441794
-
Protein composition of the intranuclear inclusions of FXTAS
-
Iwahashi CK, Yasui DH, An HJ, Greco CM, Tassone F, Nannen K, Babineau B, Lebrilla CB, Hagerman RJ, Hagerman PJ. Protein composition of the intranuclear inclusions of FXTAS. Brain 2006, 129:256-271.
-
(2006)
Brain
, vol.129
, pp. 256-271
-
-
Iwahashi, C.K.1
Yasui, D.H.2
An, H.J.3
Greco, C.M.4
Tassone, F.5
Nannen, K.6
Babineau, B.7
Lebrilla, C.B.8
Hagerman, R.J.9
Hagerman, P.J.10
-
83
-
-
34547681603
-
Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome
-
Jin P, Duan R, Qurashi A, Qin Y, Tian D, Rosser TC, Liu H, Feng Y, Warren ST. Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome. Neuron 2007, 55:556-564.
-
(2007)
Neuron
, vol.55
, pp. 556-564
-
-
Jin, P.1
Duan, R.2
Qurashi, A.3
Qin, Y.4
Tian, D.5
Rosser, T.C.6
Liu, H.7
Feng, Y.8
Warren, S.T.9
-
84
-
-
77950529507
-
Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients
-
Sellier C, Rau F, Liu Y, Tassone F, Hukema RK, Gattoni R, Schneider A, Richard S, Willemsen R, Elliott DJ, et al. Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients. EMBO J 2010, 29:1248-1261.
-
(2010)
EMBO J
, vol.29
, pp. 1248-1261
-
-
Sellier, C.1
Rau, F.2
Liu, Y.3
Tassone, F.4
Hukema, R.K.5
Gattoni, R.6
Schneider, A.7
Richard, S.8
Willemsen, R.9
Elliott, D.J.10
-
85
-
-
84884814617
-
CUG-BP, Elav-like family (CELF)-mediated alternative splicing regulation in the brain during health and disease
-
Ladd AN. CUG-BP, Elav-like family (CELF)-mediated alternative splicing regulation in the brain during health and disease. Mol Cell Neurosci 2013, 56:456-464.
-
(2013)
Mol Cell Neurosci
, vol.56
, pp. 456-464
-
-
Ladd, A.N.1
-
86
-
-
0033757702
-
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability
-
Jensen KB, Dredge BK, Stefani G, Zhong R, Buckanovich RJ, Okano HJ, Yang YY, Darnell RB. Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron 2000, 25:359-371.
-
(2000)
Neuron
, vol.25
, pp. 359-371
-
-
Jensen, K.B.1
Dredge, B.K.2
Stefani, G.3
Zhong, R.4
Buckanovich, R.J.5
Okano, H.J.6
Yang, Y.Y.7
Darnell, R.B.8
-
87
-
-
23044431574
-
Nova regulates brain-specific splicing to shape the synapse
-
Ule J, Ule A, Spencer J, Williams A, Hu JS, Cline M, Wang H, Clark T, Fraser C, Ruggiu M, et al. Nova regulates brain-specific splicing to shape the synapse. Nat Genet 2005, 37:844-852.
-
(2005)
Nat Genet
, vol.37
, pp. 844-852
-
-
Ule, J.1
Ule, A.2
Spencer, J.3
Williams, A.4
Hu, J.S.5
Cline, M.6
Wang, H.7
Clark, T.8
Fraser, C.9
Ruggiu, M.10
-
88
-
-
84880312659
-
RNA protein interaction in neurons
-
Darnell RB. RNA protein interaction in neurons. Annu Rev Neurosci 2013, 36:243-270.
-
(2013)
Annu Rev Neurosci
, vol.36
, pp. 243-270
-
-
Darnell, R.B.1
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