Airborne fine particulate matter induces multiple cell death pathways in human lung epithelial cells

Apoptosis

Volumn 19, Issue 7, 2014, Pages 1099-1112

  Deng, Xiaobei ^a   Zhang, Fang ^a   Wang, Lijuan ^b   Rui, Wei ^a   Long, Fang ^a   Zhao, Yong ^b   Chen, Deliang ^a   Ding, Wenjun ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

Apoptosis; Autophagy; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; BECLIN 1; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEINS LIGHT CHAIN 3; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE; APOPTOSIS REGULATORY PROTEIN; PARTICULATE MATTER; RAPAMYCIN;

AIRBORNE PARTICLE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL VACUOLE; CELL VIABILITY; CYTOKINE RELEASE; CYTOPLASM; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LAMELLAR BODY; LUNG ALVEOLUS EPITHELIUM; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; LUNG; METABOLISM; TUMOR CELL LINE;

ADENINE; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; EPITHELIAL CELLS; HUMANS; LUNG; OXIDATIVE STRESS; PARTICULATE MATTER; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SIROLIMUS;

EID: 84902548153     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-0980-5     Document Type: Article

References (37)

1. Donaldson K, Seaton A (2012) A short history of the toxicology of inhaled particles. Part Fibre Toxicol 9:13-25
2. Pope CA, Burnett RT, Thun MJ, Calle EE, Krewski D et al (2002) Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA 287:1132-1141 (Pubitemid 34252082)
3. Ulrich MM, Alink GM, Kumarathasan P, Vincent R, Boere AJF et al (2002) Health effects and time course of particulate matter on the cardiopulmonary system in rats with lung inflammation. J Toxicol Environ Health A 65:1571-1595 (Pubitemid 35217501)
4. Müller B, Seifart C, Barth P (1998) Effect of air pollutants on the pulmonary surfactant system. Eur J Clin Invest 28:762-777 (Pubitemid 28432130)
5. Duarte FV, Teodoro JS, Rolo AP, Palmeira CM (2011) Exposure to dibenzofuran triggers autophagy in lung cells. Toxicol Lett 209:35-42
6. Thompson CB (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462
7. Chen M, Wang J (2002) Initiator caspases in apoptosis signaling pathways. Apoptosis 7:313-319 (Pubitemid 34832255)
8. Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35:495-516
9. Park SH, Kim JH, Chi GY, Kim GY, Chang YC et al (2012) Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species. Toxicol Lett 212:252-261
10. Soldani C, Scovassi AI (2002) Poly (ADP-ribose) polymerase-1 cleavage during apoptosis: an update. Apoptosis 7:321-328 (Pubitemid 34832256)
11. 2.5) in human epithelial lung cells (L132) in culture. Toxicology 225:12-24
12. 2.5 extracts exposure on human lung epithelial cells (A549): a proteomic study. J Appl Toxicol. doi: 10.1002/jat.2910
13. Abounit K, Scarabelli TM, McCauley RB (2012) Autophagy in mammalian cells. World J Biol Chem 3:1-6
14. Baregamian N, Song J, Bailey CE, Papaconstantinou J, Evers BM et al (2009) Tumor necrosis factor-α and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis. Oxid Med Cell Longev 2:297-306
15. Klionsky D (2013) An overview of autophagy: morphology, mechanism and regulation. Antioxid Redox Signal. doi:10.1089/ars.2013.5371
16. Jin M, Klionsky DJ (2013) The core molecular machinery of autophagosome formation. Autophagy Cancer 8:25-45
17. Rubinsztein DC, Gestwicki JE, Murphy LO, Klionsky DJ (2007) Potential therapeutic applications of autophagy. Nat Rev Drug Discov 6:304-312 (Pubitemid 46505881)
18. Levine B, Kroemer G (2008) Autophagy in the pathogenesis of disease. Cell 132:27-42
19. 2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells. Toxicol In Vitro 27(6):1762-1770
20. 2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells. Cell Biol Toxicol 29:143-157
21. 3) induces apoptosis and necrosis mediated cell death through mitochondrial membrane potential damage and elevated production of reactive oxygen species in PLHC-1 fish cell line. Chemosphere 90:1201-1209
22. Gonda MA, Aaronson SA, Ellmore N, Zeve VH, Nagashima K (1976) Ultrastructural studies of surface features of human normal and tumor cells in tissue culture by scanning and transmission electron microscopy. J Natl Cancer Inst 56:245-263
23. Upadhyay D, Panduri V, Ghio A, Kamp DW (2003) Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria. Am J Respir Cell Mol Biol 29:180-187 (Pubitemid 36936645)
24. Ding WX (2012) Autophagy in toxicology: defense against xenobiotics. J Drug Metab Toxicol. doi:10.4172/2157-7609.1000e108
25. Azad MB, Chen Y, Gibson SB (2009) Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment. Antioxid Redox Signal 11:777-790
26. Moore MN (2008) Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stress. Autophagy 4:254-256
27. Zhang J, Ghio A, Chang W, Kamdar O, Rosen G et al (2007) Bim mediates mitochondria-regulated particulate matter-induced apoptosis in alveolar epithelial cells. FEBS Lett 581:4148-4152 (Pubitemid 47301849)
28. Li N, Kim S, Wang M, Froines J, Sioutas C et al (2002) Use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter. Inhal Toxicol 14:459-486 (Pubitemid 34578748)
29. Senft AP, Dalton TP, Nebert DW, Genter MB, Puga A et al (2002) Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor. Free Radic Bio Med 33:1268-1278 (Pubitemid 35246595)
30. Jung D (2009) Mitochondria as a target of benzo[a]pyrene toxicity in a PAH-adapted and Naïve. Duke University
31. Le Bras M, Clement M, Pervaiz S, Brenner C (2005) Reactive oxygen species and the mitochondrial signaling pathway of cell death. Histol Histopathol 20:205-219
32. Van Limbergen J, Stevens C, Nimmo E, Wilson D, Satsangi J (2009) Autophagy: from basic science to clinical application. Mucosal Immunol 2:315-330
33. Xu Y, Ruan S, Wu X, Chen H, Zheng K et al (2013) Autophagy and apoptosis in tubular cells following unilateral ureteral obstruction are associated with mitochondrial oxidative stress. Int J Mol Med 31:628-636
34. Eisenberg-Lerner A, Bialik S, Simon H, Kimchi A (2009) Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ 16:966-975
35. Yang Y, Xing D, Zhou F, Chen Q (2010) Mitochondrial autophagy protects against heat shock-induced apoptosis through reducing cytosolic cytochrome c release and downstream caspase-3 activation. Biochem Biophys Res Commun 395:190-195
36. Maiuri MC, Zalckvar E, Kimchi A, Kroemer G (2007) Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8:741-752 (Pubitemid 47312826)
37. Xu Y, Yu H, Qin H, Kang J, Yu C et al (2012) Inhibition of autophagy enhances cisplatin cytotoxicity through endoplasmic reticulum stress in human cervical cancer cells. Cancer Lett 314:232-243