Bim mediates mitochondria-regulated particulate matter-induced apoptosis in alveolar epithelial cells

FEBS Letters

Volumn 581, Issue 22, 2007, Pages 4148-4152

  Zhang, J ^a   Ghio, A J ^b   Chang, W ^a   Kamdar, O ^a   Rosen, G D ^a   Upadhyay, D ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Ambient air pollution particle; Apoptosis; Bim; Particulate matter

Indexed keywords

BIM PROTEIN; CASPASE 3; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN; PROTEIN BCL 2; SHORT HAIRPIN RNA;

AIRBORNE MICROORGANISM; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PARTICULATE MATTER; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CATTLE; CELL LINE, TUMOR; DNA FRAGMENTATION; EPITHELIAL CELLS; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; MODELS, BIOLOGICAL; PARTICULATE MATTER; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS; PULMONARY ALVEOLI; RATS; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 34548120786     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.07.080     Document Type: Article

References (21)

1. U.N. Environment Program and WHO Report. (1994). Air pollution in the world's megacities: a report from the U.N. Environment Programme and WHO. Environment 36, 5-37.
2. Pope C.A., Burnett R.T., Thun M.J., Calle E.E., Krewski D., Kazuhiko I., and Thurston G.D. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA 287 (2002) 1132-1141
3. Prahalad A.K., Inmon J., Dailey L.A., Madden M.C., Ghio A.J., and Gallagher J.E. Air pollution particles mediated oxidative DNA base damage in a cell free system and in human airway epithelial cells in relation to particulate metal content and bioreactivity. Chem. Res. Toxicol. 14 (2001) 879-887
4. Upadhyay D., Panduri V., Ghio A., and Kamp D.W. Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria. Am. J. Respir. Cell Mol. Biol. 29 (2003) 180-187
5. Anseth J.W., Goffin A.J., Fuller G.G., Ghio A.J., Kao P.N., and Upadhyay D. Lung surfactant gelation induced by epithelial cells exposed to air pollution or oxidative stress. Am. J. Respir. Cell Mol. Biol. 33 (2005) 161-168
6. Ferri K.F., and Kroemer G. Organelle-specific initiation of cell death pathways. Nat. Cell Biol. 3 (2001) E255-E263
7. Bortner C.D., and Cidlowski J.A. Cellular mechanisms for repressing apoptosis. Annu. Rev. Pharmacol. Toxicol. 42 (2002) 259-281
8. Green D.R., and Reed J.C. Mitochondria and apoptosis. Science 281 (1998) 1309-1312
9. Martin L.D., Krunkosky T.M., Dye J.A., Fischer B.M., Jiang N.F., Rochelle L.G., Akley N.J., Dreher K.L., and Adler K.B. The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates. Environ. Health Perspect. 105 (1997) 1301-1307
10. Cory S., Huang D.C., and Adams J.M. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22 (2003) 8590-8607
11. Huang D.C., and Strasser A. BH3-only proteins - essential initiators of apoptotic cell death. Cell 103 (2000) 839-842
12. Hiura T.S., Li N., Kaplan R., Horwitz M., Seagrave J.C., and Nel A.E. The role of a mitochondrial pathway in the induction of apoptosis by chemicals extracted from diesel exhaust particles. J. Immunol. 165 (2000) 2703-2711
13. Gross A., McDonnell J.M., and Korsmeyer S.J. Bcl-2 family members and the mitochondria in apoptosis. Genes Dev. 13 (1999) 1899-1911
14. Kurinna S.M., Tsao C.C., Nica A.F., Jiffar T., and Ruvolo P.P. Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase. Cancer Res. 64 (2004) 7852-7856
15. Chang K.C., Unsinger J., Davis C.G., Schwulst S.J., Muenzer J.T., Strasser A., and Hotchkiss R.S. Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis. FASEB J. 21 (2007) 708-719
16. Puthalakath H., Huang D.C., O'Reilly L.A., King S.M., and Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol. Cell 3 (1999) 287-296
17. Day C.L., Puthalakath H., Skea G., Strasser A., Barsukov I., Lian L.Y., Huang D.C., and Hinds M.G. Localization of dynein light chains 1 and 2 and their proapoptotic ligands. Biochem. J. 377 (2004) 597-605
18. Lei K., and Davis R.J. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl. Acad. Sci. USA 100 (2003) 2432-2437
19. Lei K., Nimnual A., Zong W.X., Kennedy N.J., Flavell R.A., Thompson C.B., Bar-Sagi D., and Davis R.J. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol. Cell Biol. 22 (2002) 4929-4942
20. Cipriani G., Rapizzi E., Vannacci A., Rizzuto R., Moroni F., and Chiarugi A. Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction. J. Biol. Chem. 280 (2005) 17227-17234
21. Dagher Z., Garcon G., Billet S., Gosset P., Ledoux F., Courcot D., Aboukais A., and Shirali P. Activation of different pathways of apoptosis by air pollution particulate matter (PM2.5) in human epithelial lung cells (L132) in culture. Toxicology 225 (2006) 12-24