Arsenic trioxide (As2O3) induces apoptosis and necrosis mediated cell death through mitochondrial membrane potential damage and elevated production of reactive oxygen species in PLHC-1 fish cell line

Chemosphere

Volumn 90, Issue 3, 2013, Pages 1201-1209

  Selvaraj, Vellaisamy ^a   Armistead, Mindy Yeager ^a   Cohenford, Menashi ^a   Murray, Elizabeth ^a  

^a MARSHALL UNIVERSITY   (United States)

Author keywords

Apoptosis; Arsenic trioxide; Necrosis; P53; PLHC 1; ROS

Indexed keywords

ARSENIC COMPOUNDS; CELL CULTURE; FISH; MAGNESIUM PRINTING PLATES; MAMMALS; MITOCHONDRIA; OXYGEN; TOXICITY;

ARSENIC TRIOXIDE; ENVIRONMENTAL CONTAMINANT; ENVIRONMENTAL POLLUTANTS; EXPERIMENTAL CONDITIONS; MITOCHONDRIAL MEMBRANE POTENTIAL; NECROSIS; PLHC-1; REACTIVE OXYGEN SPECIES;

CELL DEATH;

ARSENIC TRIOXIDE; CASPASE 3; CHEMICAL COMPOUND; CYTOCHROME C; DNA; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARSENIC; BIOCHEMISTRY; CONCENTRATION (COMPOSITION); ECOTOXICOLOGY; FISH; GENE EXPRESSION; MEMBRANE; MITOCHONDRION; MOLECULAR ANALYSIS; POLLUTION EXPOSURE; TOXICITY TEST;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PHASE; CELL CYCLE S PHASE; CELL DAMAGE; CELL DEATH; CELL LINE; CELL PROLIFERATION; CHEMICAL COMPOSITION; COMET ASSAY; CONCENTRATION (PARAMETERS); CYTOTOXICITY; DNA FRAGMENTATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FISH; FLOW CYTOMETRY; IC 50; IN VITRO STUDY; IN VIVO STUDY; MAMMAL CELL; MEDIATOR; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; POLLUTANT; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALIA; MAMMALIA;

EID: 84869885139     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.09.039     Document Type: Article

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