Multifunctional activity of a small tellurium redox immunomodulator compound, AS101, on dextran sodium sulfate-induced murine colitis

Journal of Biological Chemistry

Volumn 289, Issue 24, 2014, Pages 17215-17227

  Halpert, Gilad ^a   Eitan, Tom ^a   Voronov, Elena ^b   Apte, Ron N ^b   Rath Wolfson, Lea ^c,d   Albeck, Michael ^a   Kalechman, Yona ^a   Sredni, Benjamin ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c RABIN MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN; TELLURIUM COMPOUNDS;

ANTI-INFLAMMATORIES; ANTIAPOPTOTIC PROPERTIES; CELL ADHESION MOLECULES; CLINICAL MANIFESTATION; INFLAMMATORY BOWEL DISEASE; INTRAPERITONEAL ADMINISTRATION; MULTIFUNCTIONAL ACTIVITY; NEUROTROPHIC FACTORS;

DISEASES;

ADHESIN; ALPHA4 INTEGRIN; AMMONIUM TRICHLORO(DIOXYETHYLENE O,O')TELLURATE; BETA7 INTEGRIN; CELL ADHESION MOLECULE; CYTOKINE; DEXTRAN SULFATE; EVANS BLUE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 17; INTERLEUKIN 1BETA; PROTEIN BAX; PROTEIN BCL 2; TELLURIUM;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEXTRAN SODIUM SULFATE INDUCED MURINE COLITIS; DOWN REGULATION; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY BOWEL DISEASE; LEUKOCYTE MIGRATION; MACROPHAGE MIGRATION; MALE; MESENTERY LYMPH NODE; MOUSE; NICK END LABELING; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; UPREGULATION;

AS101; CYTOKINE; DSS; IMMUNOMODULATOR; INFLAMMATION; INFLAMMATORY BOWEL DISEASE (IBD); INNATE IMMUNITY; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTESTINE;

ADMINISTRATION, ORAL; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL ADHESION MOLECULES; COLITIS; COLON; DEXTRAN SULFATE; ETHYLENES; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOLOGIC FACTORS; INJECTIONS, INTRAPERITONEAL; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84902449058     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.536664     Document Type: Article

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