Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 299, Issue 5, 2010, Pages

  Shen, Bo ^a   Gao, Lin ^a   Hsu, Yi Te ^a   Bledsoe, Grant ^b   Hagiwara, Makato ^a   Chao, Lee ^a   Chao, Julie ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b CHARLESTON SOUTHERN UNIVERSITY   (United States)

Author keywords

Bim; Endothelial nitric oxide synthase superoxide; Endothelium; Forkhead box O 1; Tumor necrosis factor

Indexed keywords

ANGIOTENSIN II; BIM PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; KALLISTATIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEINASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSCRIPTION FACTOR FKHR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; DRUG INHIBITION; ENDOTHELIUM CELL; GENE DELIVERY SYSTEM; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ENDOTHELIUM, VASCULAR; FORKHEAD TRANSCRIPTION FACTORS; MALE; MEMBRANE PROTEINS; MODELS, ANIMAL; NADP; NERVE TISSUE PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SERPINS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78249287560     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00591.2010     Document Type: Article

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