Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats

Chemico-Biological Interactions

Volumn 190, Issue 1, 2011, Pages 45-53

  Chen, Kuan Hsing ^a,b   Hung, Cheng Chieh ^b   Hsu, Hsiang Hao ^b   Jing, Yu Hong ^c   Yang, Chih Wei ^b   Chen, Jan Kan ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c LANZHOU UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; ERK1 2; Fibronectin; Nephrin; Resveratrol; TGF smad

Indexed keywords

ALBUMIN; COLLAGEN TYPE 4; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; NEPHRIN; RESVERATROL; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DRUG MECHANISM; ENZYME INHIBITION; GLOMERULUS BASEMENT MEMBRANE; HISTOPATHOLOGY; KIDNEY HYPERTROPHY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; URINARY EXCRETION;

ANIMALS; COLLAGEN TYPE IV; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; FIBRONECTINS; HYPOGLYCEMIC AGENTS; KIDNEY; MALE; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD PROTEINS; STILBENES; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; RATTUS; RICE STRIPE VIRUS;

EID: 79952700753     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.01.033     Document Type: Article

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