-
1
-
-
80053634225
-
Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase
-
Takeuchi H, Fernández-Valdivia RC, Caswell DS, Nita-Lazar A, Rana NA, Garner TP, et al: Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase. Proc Natl Acad Sci USA 108: 16600-16605, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 16600-16605
-
-
Takeuchi, H.1
Fernández-Valdivia, R.C.2
Caswell, D.S.3
Nita-Lazar, A.4
Rana, N.A.5
Garner, T.P.6
-
2
-
-
79955561765
-
Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi
-
Fernandez-Valdivia R, Takeuchi H, Samarghandi A, Lopez M, Leonardi J, Haltiwanger RS and Jafar-Nejad H: Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi. Development 138: 1925-1934, 2011.
-
(2011)
Development
, vol.138
, pp. 1925-1934
-
-
Fernandez-Valdivia, R.1
Takeuchi, H.2
Samarghandi, A.3
Lopez, M.4
Leonardi, J.5
Haltiwanger, R.S.6
Jafar-Nejad, H.7
-
3
-
-
84856070820
-
Molecular cloning of a xylosyltransferase that transfers the second xylose to O-glucosylated epidermal growth factor repeats of notch
-
Sethi MK, Buettner FF, Ashikov A, Krylov VB, Takeuchi H, Nifantiev NE, et al: Molecular cloning of a xylosyltransferase that transfers the second xylose to O-glucosylated epidermal growth factor repeats of notch. J Biol Chem 287: 2739-2748, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 2739-2748
-
-
Sethi, M.K.1
Buettner, F.F.2
Ashikov, A.3
Krylov, V.B.4
Takeuchi, H.5
Nifantiev, N.E.6
-
4
-
-
79955445744
-
hCLP46 regulates U937 cell proliferation via Notch signaling pathway
-
Ma W, Du J, Chu Q, Wang Y, Liu L, Song M and Wang W: hCLP46 regulates U937 cell proliferation via Notch signaling pathway. Biochem Biophys Res Commun 408: 84-88, 2011.
-
(2011)
Biochem Biophys Res Commun
, vol.408
, pp. 84-88
-
-
Ma, W.1
Du, J.2
Chu, Q.3
Wang, Y.4
Liu, L.5
Song, M.6
Wang, W.7
-
5
-
-
33645231142
-
Cloning, expression and characterization of a novel human CAP10-like gene hCLP46 from CD34(+) stem/progenitor cells
-
Teng Y, Liu Q, Ma J, Liu F, Han Z, Wang Y and Wang W: Cloning, expression and characterization of a novel human CAP10-like gene hCLP46 from CD34(+) stem/progenitor cells. Gene 371: 7-15, 2006.
-
(2006)
Gene
, vol.371
, pp. 7-15
-
-
Teng, Y.1
Liu, Q.2
Ma, J.3
Liu, F.4
Han, Z.5
Wang, Y.6
Wang, W.7
-
6
-
-
76949088829
-
Overexpression of human CAP10-like protein 46 KD in T-acute lymphoblastic leukemia and acute myelogenous leukemia
-
Wang Y, Chang N, Zhang T, Liu H, Ma W, Chu Q, et al: Overexpression of human CAP10-like protein 46 KD in T-acute lymphoblastic leukemia and acute myelogenous leukemia. Genet Test Mol Biomarkers 14: 127-133, 2010.
-
(2010)
Genet Test Mol Biomarkers
, vol.14
, pp. 127-133
-
-
Wang, Y.1
Chang, N.2
Zhang, T.3
Liu, H.4
Ma, W.5
Chu, Q.6
-
7
-
-
0034657830
-
Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-beta1 is a cell cycle-independent effect and influences their hematopoietic potential
-
Pierelli L, Marone M, Bonanno G, Mozzetti S, Rutella S, Morosetti R, et al: Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-beta1 is a cell cycle-independent effect and influences their hematopoietic potential. Blood 95: 3001-3009, 2000.
-
(2000)
Blood
, vol.95
, pp. 3001-3009
-
-
Pierelli, L.1
Marone, M.2
Bonanno, G.3
Mozzetti, S.4
Rutella, S.5
Morosetti, R.6
-
8
-
-
79957772521
-
TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells
-
Cipriano R, Kan CE, Graham J, Danielpour D, Stampfer M and Jackson MW: TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells. Proc Natl Acad Sci USA 108: 8668-8673, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.108
, pp. 8668-8673
-
-
Cipriano, R.1
Kan, C.E.2
Graham, J.3
Danielpour, D.4
Stampfer, M.5
Jackson, M.W.6
-
9
-
-
0036134968
-
Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia
-
Bardeesy N, Morgan J, Sinha M, Signoretti S, Srivastava S, Loda M, et al: Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia. Mol Cell Biol 22: 635-643, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 635-643
-
-
Bardeesy, N.1
Morgan, J.2
Sinha, M.3
Signoretti, S.4
Srivastava, S.5
Loda, M.6
-
10
-
-
42249114037
-
Cross talk among Smad, MAPK, and integrin signaling pathways enhances adventitial fibroblast functions activated by transforming growth factor-beta1 and inhibited by Gax
-
Liu P, Zhang C, Feng JB, Zhao YX, Wang XP, Yang JM, et al: Cross talk among Smad, MAPK, and integrin signaling pathways enhances adventitial fibroblast functions activated by transforming growth factor-beta1 and inhibited by Gax. Arterioscler Thromb Vasc Biol 28: 725-731, 2008.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 725-731
-
-
Liu, P.1
Zhang, C.2
Feng, J.B.3
Zhao, Y.X.4
Wang, X.P.5
Yang, J.M.6
-
11
-
-
77958598499
-
TGF-β1 antisense impacts the SMAD signalling system in fibroblasts from keloid scars
-
Bran GM, Sommer UJ, Goessler UR, Hörmann K, Riedel F and Sadick H: TGF-β1 antisense impacts the SMAD signalling system in fibroblasts from keloid scars. Anticancer Res 30: 3459-3463, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 3459-3463
-
-
Bran, G.M.1
Sommer, U.J.2
Goessler, U.R.3
Hörmann, K.4
Riedel, F.5
Sadick, H.6
-
12
-
-
0032527756
-
TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300
-
Janknecht R, Wells NJ and Hunter T: TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300. Genes Dev 12: 2114-2119, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 2114-2119
-
-
Janknecht, R.1
Wells, N.J.2
Hunter, T.3
-
13
-
-
0034234964
-
A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction
-
Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, et al: A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction. Genes Dev 14: 1605-1616, 2000.
-
(2000)
Genes Dev
, vol.14
, pp. 1605-1616
-
-
Kim, R.H.1
Wang, D.2
Tsang, M.3
Martin, J.4
Huff, C.5
de Caestecker, M.P.6
-
14
-
-
0029073142
-
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
-
Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y and Wang XF: Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci USA 92: 5545-5549, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5545-5549
-
-
Datto, M.B.1
Li, Y.2
Panus, J.F.3
Howe, D.J.4
Xiong, Y.5
Wang, X.F.6
-
15
-
-
0032981481
-
Induced-expression of p16(INK4a) inhibits both CDK4-and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes
-
McConnell BB, Gregory FJ, Stott FJ, Hara E and Peters G: Induced-expression of p16(INK4a) inhibits both CDK4-and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes. Mol Cell Biol 19: 1981-1989, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1981-1989
-
-
McConnell, B.B.1
Gregory, F.J.2
Stott, F.J.3
Hara, E.4
Peters, G.5
-
16
-
-
0029147732
-
Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase
-
Aprelikova O, Xiong Y and Liu ET: Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J Biol Chem 270: 18195-18197, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 18195-18197
-
-
Aprelikova, O.1
Xiong, Y.2
Liu, E.T.3
-
17
-
-
33745470981
-
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): Its relationship with cyclins and CDK 'inhibitors'
-
Bockstaele L, Kooken H, Libert F, Paternot S, Dumont JE, de Launoit Y, et al: Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK 'inhibitors'. Mol Cell Biol 26: 5070-5085, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5070-5085
-
-
Bockstaele, L.1
Kooken, H.2
Libert, F.3
Paternot, S.4
Dumont, J.E.5
de Launoit, Y.6
-
18
-
-
0033082448
-
Identification of functional elements of p18INK4C essential for binding and inhibition of cyclin-dependent kinase (CDK) 4 and CDK6
-
Noh SJ, Li Y, Xiong Y and Guan KL: Identification of functional elements of p18INK4C essential for binding and inhibition of cyclin-dependent kinase (CDK) 4 and CDK6. Cancer Res 59: 558-564, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 558-564
-
-
Noh, S.J.1
Li, Y.2
Xiong, Y.3
Guan, K.L.4
-
19
-
-
0035187023
-
p16/p14(ARF) cell cycle regulatory pathways in primary neuroblastoma: P16 expression is associated with advanced stage disease
-
Omura-Minamisawa M, Diccianni MB, Chang RC, Batova A, Bridgeman LJ, Schiff J, et al: p16/p14(ARF) cell cycle regulatory pathways in primary neuroblastoma: p16 expression is associated with advanced stage disease. Clin Cancer Res 7: 3481-3490, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3481-3490
-
-
Omura-Minamisawa, M.1
Diccianni, M.B.2
Chang, R.C.3
Batova, A.4
Bridgeman, L.J.5
Schiff, J.6
-
20
-
-
0031897448
-
Infrequent mutation of the p16/MTS1 gene and overexpression of cyclin-dependent kinase 4 in human primary soft-tissue sarcoma
-
Yao J, Pollock RE, Lang A, Tan M, Pisters PW, Goodrich D, et al: Infrequent mutation of the p16/MTS1 gene and overexpression of cyclin-dependent kinase 4 in human primary soft-tissue sarcoma Clin Cancer Res 4: 1065-1070, 1998.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1065-1070
-
-
Yao, J.1
Pollock, R.E.2
Lang, A.3
Tan, M.4
Pisters, P.W.5
Goodrich, D.6
-
21
-
-
0033386504
-
The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4
-
Kubo A, Nakagawa K, Varma RK, Conrad NK, Cheng JQ, Lee WC, et al: The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4. Clin Cancer Res 5: 4279-4286, 1999.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4279-4286
-
-
Kubo, A.1
Nakagawa, K.2
Varma, R.K.3
Conrad, N.K.4
Cheng, J.Q.5
Lee, W.C.6
-
22
-
-
0033013980
-
Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts
-
Stein GH, Drullinger LF, Soulard A and Dulić V: Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts. Mol Cell Biol 19: 2109-2117, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2109-2117
-
-
Stein, G.H.1
Drullinger, L.F.2
Soulard, A.3
Dulić, V.4
-
23
-
-
0038666344
-
The gene ratios c-MYC:Cyclin-dependent kinase (CDK)N2A and CCND1:CDKN2A correlate with poor prognosis in squamous cell carcinoma of the head and neck
-
Akervall J, Bockmühl U, Petersen I, Yang K, Carey TE and Kurnit DM: The gene ratios c-MYC:cyclin-dependent kinase (CDK)N2A and CCND1:CDKN2A correlate with poor prognosis in squamous cell carcinoma of the head and neck. Clin Cancer Res 9: 1750-1755, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1750-1755
-
-
Akervall, J.1
Bockmühl, U.2
Petersen, I.3
Yang, K.4
Carey, T.E.5
Kurnit, D.M.6
-
24
-
-
84863407686
-
TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A
-
Mihira H, Suzuki HI, Akatsu Y, Yoshimatsu Y, Igarashi T, Miyazono K and Watabe T: TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A. J Biochem 151: 145-156, 2012.
-
(2012)
J Biochem
, vol.151
, pp. 145-156
-
-
Mihira, H.1
Suzuki, H.I.2
Akatsu, Y.3
Yoshimatsu, Y.4
Igarashi, T.5
Miyazono, K.6
Watabe, T.7
-
25
-
-
0032521170
-
Frequent deletion and 5' CpG island methylation of the p16 gene in primary malignant lymphoma of the brain
-
Zhang SJ, Endo S, Ichikawa T, Washiyama K and Kumanishi T: Frequent deletion and 5' CpG island methylation of the p16 gene in primary malignant lymphoma of the brain. Cancer Res 58: 1231-1237, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 1231-1237
-
-
Zhang, S.J.1
Endo, S.2
Ichikawa, T.3
Washiyama, K.4
Kumanishi, T.5
-
26
-
-
0030477686
-
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
-
Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D and Barrett JC: Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc Natl Acad Sci USA 93: 13742-13747, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13742-13747
-
-
Alcorta, D.A.1
Xiong, Y.2
Phelps, D.3
Hannon, G.4
Beach, D.5
Barrett, J.C.6
-
27
-
-
0030882326
-
Alterations of the Cyclin D1/p16-pRB Pathway in mantle cell lymphoma
-
Dreyling MH, Bullinger L, Ott G, Stilgenbauer S, Müller-Hermelink HK, Bentz M, et al: Alterations of the Cyclin D1/p16-pRB Pathway in mantle cell lymphoma. Cancer Res 57: 4608-4614, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 4608-4614
-
-
Dreyling, M.H.1
Bullinger, L.2
Ott, G.3
Stilgenbauer, S.4
Müller-Hermelink, H.K.5
Bentz, M.6
-
28
-
-
9444276546
-
Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: Analysis of a clinic-based population
-
FitzGerald MG, Harkin DP, Silva-Arrieta S, MacDonald DJ, Lucchina LC, Unsal H, et al: Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population. Proc Natl Acad Sci USA 93: 8541-8545, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8541-8545
-
-
FitzGerald, M.G.1
Harkin, D.P.2
Silva-Arrieta, S.3
McDonald, D.J.4
Lucchina, L.C.5
Unsal, H.6
-
29
-
-
31544459273
-
AZ703, an imidazo[1,2-a]pyridine inhibitor of cyclin-dependent kinases 1 and 2, induces E2F-1-dependent apoptosis enhanced by depletion of cyclin-dependent kinase 9
-
Cai D, Byth KF and Shapiro GI: AZ703, an imidazo[1,2-a]pyridine inhibitor of cyclin-dependent kinases 1 and 2, induces E2F-1-dependent apoptosis enhanced by depletion of cyclin-dependent kinase 9. Cancer Res 66: 435-444, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 435-444
-
-
Cai, D.1
Byth, K.F.2
Shapiro, G.I.3
-
30
-
-
0034192510
-
Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage
-
Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, et al: Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. J Neurosci 20: 3104-3114, 2000.
-
(2000)
J Neurosci
, vol.20
, pp. 3104-3114
-
-
Park, D.S.1
Morris, E.J.2
Bremner, R.3
Keramaris, E.4
Padmanabhan, J.5
Rosenbaum, M.6
-
31
-
-
0030467624
-
The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis
-
Bartkova J, Lukas J, Guldberg P, Alsner J, Kirkin AF, Zeuthen J and Bartek J: The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis. Cancer Res 56: 5475-5483, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 5475-5483
-
-
Bartkova, J.1
Lukas, J.2
Guldberg, P.3
Alsner, J.4
Kirkin, A.F.5
Zeuthen, J.6
Bartek, J.7
-
32
-
-
2442514139
-
Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells
-
Tsukiyama-Kohara K, Toné S, Maruyama I, Inoue K, Katsume A, Nuriya H, et al: Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells. J Biol Chem 279: 14531-14541, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 14531-14541
-
-
Tsukiyama-Kohara, K.1
Toné, S.2
Maruyama, I.3
Inoue, K.4
Katsume, A.5
Nuriya, H.6
-
33
-
-
0031012831
-
Inhibition of myogenesis by multiple cyclin-Cdk complexes. Coordinate regulation of myogenesis and cell cycle activity at the level of E2F
-
Guo K and Walsh K: Inhibition of myogenesis by multiple cyclin-Cdk complexes. Coordinate regulation of myogenesis and cell cycle activity at the level of E2F. J Biol Chem 272: 791-797, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 791-797
-
-
Guo, K.1
Walsh, K.2
-
34
-
-
33645829860
-
P16 protein abnormality in Epstein-Barr virus-associated gastric carcinomas
-
Ojima H, Saito K, Yamauchi H, Yamaki E, Idetu A, Hosouchi Y, Nishida Y, et al: P16 protein abnormality in Epstein-Barr virus-associated gastric carcinomas. Anticancer Res 26: 933-937, 2006.
-
(2006)
Anticancer Res
, vol.26
, pp. 933-937
-
-
Ojima, H.1
Saito, K.2
Yamauchi, H.3
Yamaki, E.4
Idetu, A.5
Hosouchi, Y.6
Nishida, Y.7
-
35
-
-
0034933793
-
Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a
-
Alani RM, Young AZ and Shifflett CB: Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a. Proc Natl Acad Sci USA 98: 7812-7816, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7812-7816
-
-
Alani, R.M.1
Young, A.Z.2
Shifflett, C.B.3
-
36
-
-
0036141797
-
Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcinomas
-
Yuen PW, Man M, Lam KY and Kwong YL: Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcinomas. J Clin Pathol 55: 58-60, 2002.
-
(2002)
J Clin Pathol
, vol.55
, pp. 58-60
-
-
Yuen, P.W.1
Man, M.2
Lam, K.Y.3
Kwong, Y.L.4
-
37
-
-
0037360095
-
Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: Modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes
-
Singh RP, Agarwal C and Agarwal R: Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis 24: 555-563, 2003.
-
(2003)
Carcinogenesis
, vol.24
, pp. 555-563
-
-
Singh, R.P.1
Agarwal, C.2
Agarwal, R.3
|