TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A

Journal of Biochemistry

Volumn 151, Issue 2, 2012, Pages 145-156

  Mihira, Hajime ^a   Suzuki, Hiroshi I ^a   Akatsu, Yuichi ^a   Yoshimatsu, Yasuhiro ^a   Igarashi, Takashi ^a   Miyazono, Kohei ^a   Watabe, Tetsuro ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

SMA; EndMT; MRTF A; Rho; TGF 2

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBRONECTIN; FIBRONECTIN 1; GELATINASE A; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR ARHGEF5; MESSENGER RNA; MYOCARDIN RELATED TRANSCRIPTION FACTOR A; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMAD PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; TRANSGELIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL STRUCTURE; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIAL MESENCHYMAL TRANSITION; INTRACELLULAR SIGNALING; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PANCREAS CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STRESS FIBER; TRANSCRIPTION REGULATION;

ANIMALS; ENDOTHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; MICE; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84863407686     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvr121     Document Type: Article

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