Activation of the CKI-CDK-Rb-E2F Pathway in Full Genome Hepatitis C Virus-expressing Cells

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 14531-14541

  Tsukiyama Kohara, Kyoko ^a,f   Toné, Shigenobu ^a,b   Maruyama, Isao ^a   Inoue, Kazuaki ^a,c   Katsume, Asao ^a,d   Nuriya, Hideko ^a   Ohmori, Hiroshi ^d   Ohkawa, Jun ^e   Taira, Kazunari ^f   Hoshikawa, Yutaka ^a   Shibasaki, Futoshi ^a   Reth, Michael ^g   Minatogawa, Yohsuke ^b   Kohara, Michinori ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

^c SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

^d CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

^g MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; PROTEINS; RNA; TUMORS; VIRUSES;

CONDITIONAL EXPRESSION SYSTEMS; HYPERPHOSPHORYLATION; INFECTIONS;

BIOCHEMISTRY;

CYCLIN DEPENDENT KINASE; VIRUS PROTEIN;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; ENZYME ACTIVITY; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MALIGNANT TRANSFORMATION; NUCLEOTIDE SEQUENCE; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UPREGULATION; VIRUS EXPRESSION; VIRUS GENOME; VIRUS MORPHOLOGY; VIRUS REPLICATION;

BLOTTING, WESTERN; CASEIN KINASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; CELL SEPARATION; CLONING, MOLECULAR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, VIRAL; GENES, REPORTER; GENOME, VIRAL; HEPACIVIRUS; HEPATOCYTES; HUMANS; IMMUNOBLOTTING; LIVER; MODELS, GENETIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN KINASES; RETINOBLASTOMA PROTEIN; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

HEPATITIS C VIRUS; RNA VIRUSES;

EID: 2442514139     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312822200     Document Type: Article

References (51)

1. Saito, I., Miyamura, T., Ohbayashi, A., Harada, H., Katayama, T., Kikuchi, S., Watanabe, Y., Koi, S., Onji, M., Ohta, Y., Choo, Q., Houghton, M., and Kuo, G. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 6547-6549
2. Kanegae, Y., Lee, G., Sato, Y., Tanaka, M., Nakai, M., Sakaki, T., Sugano, S., and Saito, I. (1995) Nucleic Acids Res. 23, 3816-3821
3. Matsumoto, M., Hsieh, T. Y., Zhu, N., VanArsdale, T., Hwang, S. B., Jeng, K. S., Gorbalenya, A. E., Lo, S. Y., Ou, J. H., Ware, C. F., and Lai, M. M. (1997) J. Virol. 71, 1301-1309
4. Zhu, N., Khoshnan, A., Schneider, R., Matsumoto, M., Dennert, G., Ware, C., and Lai, M. M. (1998) J. Virol. 72, 3691-3697
5. Marusawa, H., Hijikata, M., Chiba, T., and Shimotohno, K. (1999) J. Virol. 73, 4713-4720
6. Machida, K., Tsukiyama-Kohara, K., Seike, E., Tone, S., Shibasaki, F., Shimizu, M., Takahashi, H., Hayashi, Y., Funata, N., Taya, C., Yonekawa, H., and Kohara, M. (2001) J. Biol. Chem. 276, 12140-12146
7. Ray, R. B., Lagging, L. M., Meyer, K., and Ray, R. (1996) J. Virol. 70, 4438-4443
8. Chang, J., Yang, S. H., Cho, Y. G., Hwang, S. B., Hahn, Y. S., and Sung, Y. C. (1998) J. Virol. 72, 3060-3065
9. Jin, D.-Y., Wang, H.-L., Zhou, Y., Chun, A. C. S., Kibler, K. V., Hou, Y.-D., Kung, H.-F., and Jeang, K.-T. (2000) EMBO J. 19, 729-740
10. Yoshida, T., Hanada, T., Tokuhisa, T., Kosai, K., Sata, M., Kohara, M., and Yoshimura, A. (2002) J. Exp. Med. 196, 641-653
11. Sakamuro, D., Furukawa, T., and Takegami, T. (1995) J. Virol. 69, 3893-3896
12. Park, J. S., Yang, J. M., and Min, M. K. (2000) Biochem. Biophys. Res. Commun. 267, 581-587
13. Moriya, K., Fujie, H., Shintani, Y., Yotsuyanagi, H., Tsutsumi, T., Ishibashi, K., Matsuura, Y., Kimura, S., Miyamura, T., and Koike, K. (1998) Nat. Med. 4, 1065-1067
14. Honda, A., Arai, Y., Hirota, N., Sato, T., Ikegaki, J., Koizumi, T., Hatano, M., Kohara, M., Moriyama, T., Imawari, M., Shimotohno, K., and Tokuhisa, T. (1999) J. Med. Virol. 59, 281-289
15. Wakita, T., Taya, C., Katsume, A., Kato, J., Yonekawa, H., Kanegae, Y., Saito, I., Hayashi, Y., Koike, M., and Kohara, M. (1998) J. Biol. Chem. 273, 9001-9006
16. Lerat, H., Honda, M., Beard, M. R., Loesch, K., Sun, J., Yang, Y., Okuda, M., Gosert, R., Xiao, S. Y., Weinman, S. A., and Lemon, S. M. (2002) Gastroenterology 122, 352-365
17. Shibata, M., Morizane, T., Uchida, T., Yamagami, T., Onozuka, Y., Nakano, M., Mitamura, K., and Ueno, Y. (1998) Lancet 351, 1773-1777
18. Lohmann, V., Korner, F., Koch, J., Herian, U., Theilmann, L., and Bartenschlager, R. (1999) Science 285, 110-113
19. Blight, K. J., McKeating, J. A., Marcotrigiano, J., and Rice, C. M. (2003) J. Virol. 77, 3181-3190
20. Hsu, I. C., Tokiwa, T., Bennett, W., Metcalf, R. A., Welsh, J. A., Sun, T., and Harris, C. C. (1993) Carcinogenesis 14, 987-992
21. Lee, T. K., Lau, T. C., and Ng, I. O. (2002) Cancer Chemother. Pharmacol. 49, 78-86
22. Knowles, B. B., Howe, C. C., and Aden, D. P. (1980) Science 209, 497-499
23. Zauberman, A., Oren, M., and Zipori, D. (1997) Oncogene 15, 1705-1711
24. Niwa, H., Yamamura, K., and Miyazaki, J. (1991) Gene (Amst.) 108, 193-199
25. Shimayama, T., Nishikawa, S., and Taira, K. (1995) Biochemistry 34, 3649-3654
26. Suh, Y. A., Kumar, P. K., Nishikawa, F., Kayano, E., Nakai, S., Odai, O., Uesugi, S., Taira, K., and Nishikawa, S. (1992) Nucleic Acids Res. 20, 747-753
27. Zhang, Y., Riesterer, C., Ayrall, A. M., Sablitzky, F., Littlewood, T. D., and Reth, M. (1996) Nucleic Acids Res. 24, 543-548
28. Tsukiyama-Kohara, K., Poulin, F., Kohara, M., DeMaria, C. T., Cheng, A., Wu, Z., Gingras, A.-C., Katsume, A., Elchebly, M., Spiegelman, B. M., Harper, M.-E., Tremblay, M. L., and Sonenberg, N. (2001) Nat. Med. 7, 1128-1132
29. Yasui, K., Wakita, T., Tsukiyama-Kohara, K., Funahashi, S. I., Ichikawa, M., Kajita, T., Moradpour, D., Wands, J. R., and Kohara, M. (1998) J. Virol. 72, 6048-6055
30. Tanaka, T., Lau, J. Y., Mizokami, M., Orito, E., Tanaka, E., Kiyosawa, K., Yasui, K., Ohta, Y., Hasegawa, A., Tanaka, S., and Kohara, M. (1995) J. Hepatol. 23, 742-745
31. Ikeda, M. A., Jakoi, L., and Nevins, J. R. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3215-3220
32. Patrick, G. N., Zhou, P., Kwon, Y. T., Howley, P. M., and Tsai, L. H. (1998) J. Biol. Chem. 273, 24057-24064
33. Takeuchi, T., Katsume, A., Tanaka, T., Abe, A., Inoue, K., Tsukiyama-Kohara, K., Kawaguchi, R., Tanaka, S., and Kohara, M. (1999) Gastroenterology 116, 636-642
34. Grana, X., and Reddy, E. P. (1995) Oncogene 11, 211-219
35. Lundberg, A. S., and Weinberg, R. A. (1998) Mol. Cell. Biol. 18, 753-761
36. Hui, A. M., Makuuchi, M., and Li, X. (1998) Hepatogastroenterology 45, 1635-1642
37. Yin, M. B., Voigt, W., Panadero, A., Vanhoefer, U., Frank, C., Pajovic, S., Azizkhan, J., and Rustum, Y. M. (1997) Mol. Pharmacol. 51, 630-636
38. Ma, Y., Prigent, S. A., Born, T. L., Monell, C. R., Feramisco, J. R., and Bertolaet, B. L. (1999) Cancer Res. 59, 5341-5348
39. Higashitsuji, H., Itoh, K., Nagao, T., Dawson, S., Nonoguchi, K., Kido, T., Mayer, R. J., Arii, S., and Fujita, J. (2000) Nat. Med. 6, 96-99
40. Harbour, J. W., Luo, R. X., Dei Santi, A., Postigo, A. A., and Dean, D. C. (1999) Cell 98, 859-869
41. Ruesch, M. N., and Laimins, L. A. (1997) J. Virol. 71, 5570-5578
42. O'Brien, V., and Campo, M. S. (1998) Oncogene 17, 293-301
43. Nevins, J. R., Leone, G., DeGregori, J., and Jakoi, L. (1997) J. Cell. Physiol. 173, 233-236
44. Weinberg, R. A. (1996) Cell 85, 457-459
45. Woitach, J. T., Zhang, M., Niu, C. H., and Thorgoirsson, S. S. (1998) Nat. Genet. 19, 371-374
46. Sangfelt, O., Erickson, S., Einhorn, S., and Grander, D. (1997) Oncogene 14, 415-423
47. Sangfelt, O., Erickson, S., Castro, J., Heiden, T., Gustafsson, A., Einhorn, S., and Grander, D. (1999) Oncogene 18, 2798-2810
48. Kirch, H. C., Putzer, B., Brockmann, D., Esche, H., and Kloke, O. (1997) Eur. J. Biochem. 246, 736-744
49. Servant, M. J., Grandvaux, N., and Hiscott, J. (2002) Biochem. Pharmacol. 64, 985-992
50. Friebe, P., Lohmann, V., Krieger, N., and Bartenschlager, R. (2001) J. Virol. 75, 12647-12057
51. Matsushime, H., Quelle, D. E., Shultleff, S. A., Shibuya, M., Sherr, C. J., and Kato, J. Y. (1994) Mol. Cell Biol. 14, 2066-2076