-
1
-
-
0028070631
-
Three peptides from the atrial natriuretic factor prohormone amino terminus lower blood pressure and produce diuresis, natriuresis, and/or kaliuresis in humans
-
Vesely DL, Douglass MA, Dietz JR, Gower WR Jr., McCormick MT, Rodriguez-Paz G and Shocken DD: Three peptides from the atrial natriuretic factor prohormone amino terminus lower blood pressure and produce diuresis, natriuresis, and/or kaliuresis in humans. Circulation 90: 1129-1140, 1994.
-
(1994)
Circulation
, vol.90
, pp. 1129-1140
-
-
Vesely, D.L.1
Douglass, M.A.2
Dietz, J.R.3
Gower, W.R.4
McCormick, M.T.5
Rodriguez-Paz, G.6
Shocken, D.D.7
-
2
-
-
0028324621
-
Negative feedback of atrial natriuretic peptides
-
Vesely DL, Douglass MA, Dietz JR, Gower WR Jr., McCormick MT, Rodriguez-Paz G and Schocken DD: Negative feedback of atrial natriuretic peptides. J Clin Endocrinol Metab 78: 1128-1134, 1994.
-
(1994)
J Clin Endocrinol Metab
, vol.78
, pp. 1128-1134
-
-
Vesely, D.L.1
Douglass, M.A.2
Dietz, J.R.3
Gower, W.R.4
McCormick, M.T.5
Rodriguez-Paz, G.6
Schocken, D.D.7
-
3
-
-
84879676087
-
Natriuretic hormones
-
Fifth Edition. Alpern RJ, Caplan M, and Moe OW (eds.)., San Diego, CA: Elsevier, Academic Press
-
Vesely DL: Natriuretic Hormones. In: Seldin and Giebisch's The Kidney: Physiology and Pathophysiology, Fifth Edition. Alpern RJ, Caplan M, and Moe OW (eds.). San Diego, CA: Elsevier, Academic Press, pp. 1241-1281, 2013.
-
(2013)
Seldin and Giebisch's the Kidney: Physiology and Pathophysiology
, pp. 1241-1281
-
-
Vesely, D.L.1
-
4
-
-
0032575292
-
Vessel dilator enhances sodium and water excretion and has beneficial hemodynamic effects in persons with congestive heart failure
-
Vesely DL, Dietz JR, Parks JR, Baig M, McCormick MT, Cintron G and Schocken DD: Vessel dilator enhances sodium and water excretion and has beneficial hemodynamic effects in persons with congestive heart failure. Circulation 98: 323-329, 1998.
-
(1998)
Circulation
, vol.98
, pp. 323-329
-
-
Vesely, D.L.1
Dietz, J.R.2
Parks, J.R.3
Baig, M.4
McCormick, M.T.5
Cintron, G.6
Schocken, D.D.7
-
5
-
-
0032888296
-
Comparison of vessel dilator and long acting natriuretic peptide in the treatment of congestive heart failure
-
Vesely DL, Dietz JR, Parks JR, Antwi EK, Overton RM, McCormick, MT, Cintron G and Schocken DD: Comparison of vessel dilator and long acting natriuretic peptide in the treatment of congestive heart failure. Am Heart J 138: 625-632, 1999.
-
(1999)
Am Heart J
, vol.138
, pp. 625-632
-
-
Vesely, D.L.1
Dietz, J.R.2
Parks, J.R.3
Antwi, E.K.4
Overton, R.M.5
McCormick, M.T.6
Cintron, G.7
Schocken, D.D.8
-
6
-
-
0034082202
-
Amelioration with vessel dilator of acute tubular necrosis and renal failure established for two days
-
Clark LC, Farghaly H, Saba SR and Vesely DL: Amelioration with vessel dilator of acute tubular necrosis and renal failure established for two days. Am J Physiol 278: H1555-H1564, 2000.
-
(2000)
Am J Physiol
, vol.278
, pp. H1555-H1564
-
-
Clark, L.C.1
Farghaly, H.2
Saba, S.R.3
Vesely, D.L.4
-
7
-
-
0038824872
-
Natriuretic peptides and acute renal failure
-
Vesely DL: Natriuretic peptides and acute renal failure. Am J Physiol 285: F167-F177, 2003.
-
(2003)
Am J Physiol
, vol.285
, pp. F167-F177
-
-
Vesely, D.L.1
-
9
-
-
0004148866
-
Molecular biology of the natriuretic peptides
-
Vesely DL (ed.), Trivandum, India: Research Signpost
-
Gardner DG, Kovacic-Milivojevic BK and Garmai M: Molecular biology of the natriuretic peptides. In: Atrial Natriuretic Peptides. Vesely DL (ed.) Trivandum, India: Research Signpost pp. 15-38, 1997.
-
(1997)
Atrial Natriuretic Peptides
, pp. 15-38
-
-
Gardner, D.G.1
Kovacic-Milivojevic, B.K.2
Garmai, M.3
-
10
-
-
0004159103
-
-
Englewood Cliffs, NJ: Prentice Hall
-
Vesely DL: Atrial Natriuretic Hormones. Englewood Cliffs, NJ: Prentice Hall, pp. 1-256, 1992.
-
(1992)
Atrial Natriuretic Hormones
, pp. 1-256
-
-
Vesely, D.L.1
-
11
-
-
0023730740
-
Isolation and structural analysis of "urodilatin," a new peptide of the cardiodilatin-(ANP)-family, extracted from human urine
-
Schulz-Knappe P, Forssmann K, Herbst E, Hock D, Pipkorn R and Forssman WG: Isolation and structural analysis of "urodilatin," a new peptide of the cardiodilatin-(ANP)-family, extracted from human urine. Klin Wochenschr 66: 752-759, 1988.
-
(1988)
Klin Wochenschr
, vol.66
, pp. 752-759
-
-
Schulz-Knappe, P.1
Forssmann, K.2
Herbst, E.3
Hock, D.4
Pipkorn, R.5
Forssman, W.G.6
-
12
-
-
0034876188
-
Urodilatin, a natriuretic stimulating guanylate cyclase, and the phosphodiase five inhibitor dipyridamole attenuate experimental pulmonary hypertension
-
Schermuly RT, Weissman N, Enke B, Ghofrani HA, Forssmann WG, Grimminger F, Seeger W and Walmarth D: Urodilatin, a natriuretic stimulating guanylate cyclase, and the phosphodiase five inhibitor dipyridamole attenuate experimental pulmonary hypertension. Am J Respir Cell Mol Biol 25: 219-225, 2001.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 219-225
-
-
Schermuly, R.T.1
Weissman, N.2
Enke, B.3
Ghofrani, H.A.4
Forssmann, W.G.5
Grimminger, F.6
Seeger, W.7
Walmarth, D.8
-
13
-
-
0026656866
-
Molecular biology and biochemistry of the natriuretic peptide system. I. Natriuretic peptides
-
Nakao K, Ogawa Y, Suga S and Imura H: Molecular biology and biochemistry of the natriuretic peptide system. I. Natriuretic peptides. J Hypertens 10: 907-912, 1992.
-
(1992)
J Hypertens
, vol.10
, pp. 907-912
-
-
Nakao, K.1
Ogawa, Y.2
Suga, S.3
Imura, H.4
-
14
-
-
0026776795
-
A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis augusticeps)
-
Schweitz H, Vigne P, Moinier D, Frelin C and Lazdunski M: A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis augusticeps). J Biol Chem 267: 13928-13932, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 13928-13932
-
-
Schweitz, H.1
Vigne, P.2
Moinier, D.3
Frelin, C.4
Lazdunski, M.5
-
15
-
-
0242469264
-
Four peptides decrease the number of human pancreatic adenocarcinoma cells
-
Vesely BA, McAfee Q, Gower WR Jr. and Vesely DL: Four peptides decrease the number of human pancreatic adenocarcinoma cells. Eur J Clin Invest 33: 998-1005, 2003.
-
(2003)
Eur J Clin Invest
, vol.33
, pp. 998-1005
-
-
Vesely, B.A.1
McAfee, Q.2
Gower, W.R.3
Vesely, D.L.4
-
16
-
-
13244253639
-
Four peptide hormones decrease the number of human breast adenocarcinoma cells
-
Vesely BA, Song S, Sanchez-Ramos J, Fitz SR, Solivan SR, Gower WR Jr. and Vesely DL: Four peptide hormones decrease the number of human breast adenocarcinoma cells. Eur J Clin Invest 35: 60-69, 2005.
-
(2005)
Eur J Clin Invest
, vol.35
, pp. 60-69
-
-
Vesely, B.A.1
Song, S.2
Sanchez-Ramos, J.3
Fitz, S.R.4
Solivan, S.R.5
Gower, W.R.6
Vesely, D.L.7
-
17
-
-
27844453822
-
Four peptide hormones specific decrease (up to 97%) of human prostate carcinoma cells
-
Vesely BA, Alli AA, Song S, Gower WR Jr., Sanchez-Ramos J and Vesely DL: Four peptide hormones specific decrease (up to 97%) of human prostate carcinoma cells. Eur J Clin Invest 35: 700-710, 2005.
-
(2005)
Eur J Clin Invest
, vol.35
, pp. 700-710
-
-
Vesely, B.A.1
Alli, A.A.2
Song, S.3
Gower, W.R.4
Sanchez-Ramos, J.5
Vesely, D.L.6
-
18
-
-
33745697992
-
Four peptides decrease human colon adenocarcinoma cell number and DNA synthesis via guanosine 3',5'-cyclic monophosphate
-
Gower WR Jr., Vesely BA, Alli AA and Vesely DL: Four peptides decrease human colon adenocarcinoma cell number and DNA synthesis via guanosine 3',5'-cyclic monophosphate. Int J Gastrointestinal Cancer 36: 77-87, 2006.
-
(2006)
Int J Gastrointestinal Cancer
, vol.36
, pp. 77-87
-
-
Gower, W.R.1
Vesely, B.A.2
Alli, A.A.3
Vesely, D.L.4
-
19
-
-
33749989517
-
Urodilatin and four cardiac hormones decrease human renal carcinoma cell number
-
Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR Jr. and Vesely DL: Urodilatin and four cardiac hormones decrease human renal carcinoma cell number. Eur J Clin Invest 36: 810-819, 2006.
-
(2006)
Eur J Clin Invest
, vol.36
, pp. 810-819
-
-
Vesely, B.A.1
Eichelbaum, E.J.2
Alli, A.A.3
Sun, Y.4
Gower, W.R.5
Vesely, D.L.6
-
20
-
-
37549072766
-
Four cardiac hormones cause cell death in 81% of human ovarian adenocarcinoma cells
-
Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR Jr. and Vesely DL: Four cardiac hormones cause cell death in 81% of human ovarian adenocarcinoma cells. Cancer Therapy 5: 97-104, 2007.
-
(2007)
Cancer Therapy
, vol.5
, pp. 97-104
-
-
Vesely, B.A.1
Eichelbaum, E.J.2
Alli, A.A.3
Sun, Y.4
Gower, W.R.5
Vesely, D.L.6
-
21
-
-
34347351303
-
Four cardiac hormones decrease up to 82% of human medullary thyroid carcinoma cells within 24 hours
-
Eichelbaum EJ, Vesely BA, Alli AA, Sun Y, Gower WR Jr. and Vesely DL: Four cardiac hormones decrease up to 82% of human medullary thyroid carcinoma cells within 24 hours. Endocrine 30: 325-332, 2006.
-
(2006)
Endocrine
, vol.30
, pp. 325-332
-
-
Eichelbaum, E.J.1
Vesely, B.A.2
Alli, A.A.3
Sun, Y.4
Gower, W.R.5
Vesely, D.L.6
-
22
-
-
33646543683
-
Primary malignant tumors of the heart: Four cardiovascular hormones decrease the number and DNA synthesis of human angiosarcoma cells
-
Vesely BA, Alli A, Song S, Sanchez-Ramos, J, Fitz SR, Gower WR Jr. and Vesely DL: Primary malignant tumors of the heart: Four cardiovascular hormones decrease the number and DNA synthesis of human angiosarcoma cells. Cardiology 105: 226-233, 2006.
-
(2006)
Cardiology
, vol.105
, pp. 226-233
-
-
Vesely, B.A.1
Alli, A.2
Song, S.3
Sanchez-Ramos, J.4
Fitz, S.R.5
Gower, W.R.6
Vesely, D.L.7
-
23
-
-
38449123520
-
Four cardiac hormones cause cell death of melanoma cells and inhibit their DNA synthesis
-
Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR Jr. and Vesely DL: Four cardiac hormones cause cell death of melanoma cells and inhibit their DNA synthesis. Am J Med Sci 334: 342-349, 2007.
-
(2007)
Am J Med Sci
, vol.334
, pp. 342-349
-
-
Vesely, B.A.1
Eichelbaum, E.J.2
Alli, A.A.3
Sun, Y.4
Gower, W.R.5
Vesely, D.L.6
-
24
-
-
34447295110
-
Four cardiac hormones eliminate four-fold more human glioblastoma cells than green mamba snake peptide
-
Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR Jr. and Vesely DL: Four cardiac hormones eliminate four-fold more human glioblastoma cells than green mamba snake peptide. Cancer Lett 254: 94-101, 2007.
-
(2007)
Cancer Lett
, vol.254
, pp. 94-101
-
-
Vesely, B.A.1
Eichelbaum, E.J.2
Alli, A.A.3
Sun, Y.4
Gower, W.R.5
Vesely, D.L.6
-
25
-
-
20444439224
-
Five cardiac hormones decrease the number of human small-cell lung cancer cells
-
Vesely BA, Song S, Sanchez-Ramos J, Fitz SR, Gower WR Jr. and Vesely DL: Five cardiac hormones decrease the number of human small-cell lung cancer cells. Eur J Clin Invest 35: 388-398, 2005.
-
(2005)
Eur J Clin Invest
, vol.35
, pp. 388-398
-
-
Vesely, B.A.1
Song, S.2
Sanchez-Ramos, J.3
Fitz, S.R.4
Gower, W.R.5
Vesely, D.L.6
-
26
-
-
33644637108
-
Vessel dilator: Most potent of the atrial natriuretic peptides in decreasing the number and DNA synthesis of human squamous lung cancer cells
-
Vesely BA, Fitz SR, Gower WR Jr. and Vesely DL: Vessel dilator: Most potent of the atrial natriuretic peptides in decreasing the number and DNA synthesis of human squamous lung cancer cells. Cancer Lett 233: 226-231, 2006.
-
(2006)
Cancer Lett
, vol.233
, pp. 226-231
-
-
Vesely, B.A.1
Fitz, S.R.2
Gower, W.R.3
Vesely, D.L.4
-
27
-
-
84865691151
-
New anticancer agents: Hormones made within the heart
-
Vesely DL: New anticancer agents: Hormones made within the heart. Anticancer Res 32: 2515-2522, 2012.
-
(2012)
Anticancer Res
, vol.32
, pp. 2515-2522
-
-
Vesely, D.L.1
-
28
-
-
34250172696
-
Elimination of up to 80% of human pancreatic adenocarcinomas in athymic mice by cardiac hormones
-
Vesely DL, Eichelbaum EJ, Sun Y, Alli AA, Vesely BA, Luther SL and Gower WR Jr.: Elimination of up to 80% of human pancreatic adenocarcinomas in athymic mice by cardiac hormones. In Vivo 21: 445-452, 2007.
-
(2007)
In Vivo
, vol.21
, pp. 445-452
-
-
Vesely, D.L.1
Eichelbaum, E.J.2
Sun, Y.3
Alli, A.A.4
Vesely, B.A.5
Luther, S.L.6
Gower, W.R.7
-
29
-
-
47649105292
-
Cardiac hormones and urodilatin eliminate up to 86% of human small-cell lung carcinomas in mice
-
Eichelbaum EJ, Sun Y, Alli AA, Gower WR Jr. and Vesely DL: Cardiac hormones and urodilatin eliminate up to 86% of human small-cell lung carcinomas in mice. Eur J Clin Invest 38: 562-570, 2008.
-
(2008)
Eur J Clin Invest
, vol.38
, pp. 562-570
-
-
Eichelbaum, E.J.1
Sun, Y.2
Alli, A.A.3
Gower, W.R.4
Vesely, D.L.5
-
30
-
-
37349091248
-
Four cardiac hormones eliminate up to twothirds of human breast cancers in athymic mice
-
Vesely DL, Vesely BA, Eichelbaum EJ, Sun Y, Alli AA and Gower WR Jr.: Four cardiac hormones eliminate up to twothirds of human breast cancers in athymic mice. In Vivo 21: 973-978, 2007.
-
(2007)
In Vivo
, vol.21
, pp. 973-978
-
-
Vesely, D.L.1
Vesely, B.A.2
Eichelbaum, E.J.3
Sun, Y.4
Alli, A.A.5
Gower, W.R.6
-
31
-
-
64949135331
-
Vessel dilator and kaliuretic peptide inhibit Ras in human prostate cancer cells
-
Sun Y, Eichelbaum EJ, Skelton WP IV, Lenz A, Regales N, Wang H and Vesely DL: Vessel dilator and kaliuretic peptide inhibit Ras in human prostate cancer cells. Anticancer Res 29: 971-975, 2009.
-
(2009)
Anticancer Res
, vol.29
, pp. 971-975
-
-
Sun, Y.1
Eichelbaum, E.J.2
Skelton, W.P.3
Lenz, A.4
Regales, N.5
Wang, H.6
Vesely, D.L.7
-
32
-
-
67650925065
-
Atrial natriuretic peptide and long-acting natriuretic peptide inhibit Ras in human prostate cancer cells
-
Sun Y, Eichelbaum EJ, Lenz A, Skelton WP IV, Wang H and Vesely DL: Atrial natriuretic peptide and long-acting natriuretic peptide inhibit Ras in human prostate cancer cells. Anticancer Res 29: 1889-1893, 2009.
-
(2009)
Anticancer Res
, vol.29
, pp. 1889-1893
-
-
Sun, Y.1
Eichelbaum, E.J.2
Lenz, A.3
Skelton, W.P.4
Wang, H.5
Vesely, D.L.6
-
33
-
-
34249288341
-
Vessel dilator and kaliuretic peptide inhibit MEK-1/2 activation in human prostate cancer cells
-
Sun Y, Eichelbaum EJ, Wang H and Vesely DL: Vessel dilator and kaliuretic peptide inhibit MEK-1/2 activation in human prostate cancer cells. Anticancer Res 27: 1387-1392, 2007.
-
(2007)
Anticancer Res
, vol.27
, pp. 1387-1392
-
-
Sun, Y.1
Eichelbaum, E.J.2
Wang, H.3
Vesely, D.L.4
-
34
-
-
37349025338
-
Atrial natriuretic peptide and long acting natriuretic peptide inhibit MEK-1/2 activation in human prostate cancer cells
-
Sun Y, Eichelbaum EJ, Wang H and Vesely DL: Atrial natriuretic peptide and long acting natriuretic peptide inhibit MEK-1/2 activation in human prostate cancer cells. Anticancer Res 27: 3813-3818, 2007.
-
(2007)
Anticancer Res
, vol.27
, pp. 3813-3818
-
-
Sun, Y.1
Eichelbaum, E.J.2
Wang, H.3
Vesely, D.L.4
-
35
-
-
33750741904
-
Vessel dilator and kaliuretic peptide inhibit activation of ERK-1/2 in human prostate cancer cells
-
Sun Y, Eichelbaum EJ, Wang H and Vesely DL: Vessel dilator and kaliuretic peptide inhibit activation of ERK-1/2 in human prostate cancer cells. Anticancer Res 26: 3217-3222, 2006.
-
(2006)
Anticancer Res
, vol.26
, pp. 3217-3222
-
-
Sun, Y.1
Eichelbaum, E.J.2
Wang, H.3
Vesely, D.L.4
-
36
-
-
33845930794
-
Atrial natriuretic peptide and long acting natriuretic peptide inhibit ERK-1/2 in prostate cancer cells
-
Sun Y, Eichelbaum EJ, Wang H and Vesely DL: Atrial natriuretic peptide and long acting natriuretic peptide inhibit ERK-1/2 in prostate cancer cells. Anticancer Res 26: 4143-4148, 2006.
-
(2006)
Anticancer Res
, vol.26
, pp. 4143-4148
-
-
Sun, Y.1
Eichelbaum, E.J.2
Wang, H.3
Vesely, D.L.4
-
37
-
-
84858791307
-
Cardiac hormones are c-JUN- N -terminal kinase 2-inhibiting peptides
-
Lane ML, Santana O, Frost CD, Nguyen J, Guerrero J, Skelton WP IV, Skelton M and Vesely DL: Cardiac hormones are c-JUN- N -Terminal Kinase 2-Inhibiting peptides. Anticancer Res 32: 721-726, 2012.
-
(2012)
Anticancer Res
, vol.32
, pp. 721-726
-
-
Lane, M.L.1
Santana, O.2
Frost, C.D.3
Nguyen, J.4
Guerrero, J.5
Skelton, W.P.6
Skelton, M.7
Vesely, D.L.8
-
38
-
-
0028329953
-
Unk1 - A protein-kinase stimulated by UV-light and Ha-Ras that binds and phosphorylates the c-JUN activation domain
-
Derijard R, Hibi M, Wu IH, Barrett T, Su B, Teng TL, Karin M and Davis RJ: Unk1 - a protein-kinase stimulated by UV-light and Ha-Ras that binds and phosphorylates the c-JUN activation domain. Cell 76: 1025-1037, 1994.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, R.1
Hibi, M.2
Wu, I.H.3
Barrett, T.4
Su, B.5
Teng, T.L.6
Karin, M.7
Davis, R.J.8
-
39
-
-
0028568217
-
Differential activation of ERK and JNK mitogen-activated protein kinases for RAF-1 and MEKK
-
Minden A, Lin A, McMahon M, Lange-Carter C, Derijard B, Davis RJ, Johnson GL and Karin M: Differential activation of ERK and JNK mitogen-activated protein kinases for RAF-1 and MEKK. Science 266: 1719-1723, 1994.
-
(1994)
Science
, vol.266
, pp. 1719-1723
-
-
Minden, A.1
Lin, A.2
McMahon, M.3
Lange-Carter, C.4
Derijard, B.5
Davis, R.J.6
Johnson, G.L.7
Karin, M.8
-
40
-
-
0034644526
-
Linking colorectal cancer to WNT signaling
-
Bienz M and Clevers H: Linking colorectal cancer to WNT signaling. Cell 103: 311-320, 2000.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
41
-
-
84862170024
-
Drugging WNT signaling in cancer
-
Polakis P: Drugging WNT signaling in cancer. EMBO Journal 31: 2737-2746, 2012.
-
(2012)
EMBO Journal
, vol.31
, pp. 2737-2746
-
-
Polakis, P.1
-
42
-
-
20444449617
-
Oncogenic KRAS stimulates WNT signaling in colon cancer through inhibition of GS-3β
-
Li J, Mizukami Y, Zhang X, Jo W-S and Chung DC: Oncogenic KRAS stimulates WNT signaling in colon cancer through inhibition of GS-3β. Gastroenterology 128: 1907-1918, 2005.
-
(2005)
Gastroenterology
, vol.128
, pp. 1907-1918
-
-
Li, J.1
Mizukami, Y.2
Zhang, X.3
Jo, W.-S.4
Chung, D.C.5
-
43
-
-
0032584108
-
Impact of oncogenes in tumor angiogenesis mutant KRAS up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells
-
Okada R, Rak JW, Croix BS, Lieubeau B, Kaya M, Roncari L, Shirasawa S, Sasazuki T and Kerbel RS: Impact of oncogenes in tumor angiogenesis mutant KRAS up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells. Proc Natl Acad Sci USA 95: 3609-3614, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3609-3614
-
-
Okada, R.1
Rak, J.W.2
Croix, B.S.3
Lieubeau, B.4
Kaya, M.5
Roncari, L.6
Shirasawa, S.7
Sasazuki, T.8
Kerbel, R.S.9
-
44
-
-
84875885225
-
Cardiac hormones are novel inhibitors of WNT-3a in human cancer cells
-
Skelton WP IV, Skelton M and Vesely DL: Cardiac hormones are novel inhibitors of WNT-3a in human cancer cells. Cancer Therapy 9: 24-29, 2013.
-
(2013)
Cancer Therapy
, vol.9
, pp. 24-29
-
-
Skelton, W.P.1
Skelton, M.2
Vesely, D.L.3
-
45
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J: Tumor angiogenesis: therapeutic implications. New Engl J Med 295: 1182-1186, 1971.
-
(1971)
New Engl J Med
, vol.295
, pp. 1182-1186
-
-
Folkman, J.1
-
46
-
-
4143136640
-
Vascular endothelial growth factor: Basic science and clinical progress
-
Ferrara N: Vascular endothelial growth factor: Basic science and clinical progress. Endocrine Reviews 25: 581-611, 2004.
-
(2004)
Endocrine Reviews
, vol.25
, pp. 581-611
-
-
Ferrara, N.1
-
47
-
-
0016218630
-
Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation
-
Liotta LA, Kleinerman J and Saidel GM: Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res 34: 997-1004.
-
Cancer Res
, vol.34
, pp. 997-1004
-
-
Liotta, L.A.1
Kleinerman, J.2
Saidel, G.M.3
-
48
-
-
10644279947
-
Vascular endothelium growth factor
-
Hoeben A, Landuyt B, Highley MS, Wilders H, Van Oosterom AT and DeBruijn EA: Vascular endothelium growth factor. Pharmacological Rev 56: 549-580, 2004.
-
(2004)
Pharmacological Rev
, vol.56
, pp. 549-580
-
-
Hoeben, A.1
Landuyt, B.2
Highley, M.S.3
Wilders, H.4
Van Oosterom, A.T.5
DeBruijn, E.A.6
-
49
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery. Nature reviews
-
Folkman J: Angiogenesis: an organizing principle for drug discovery. Nature Reviews. Drug Discovery 6: 273-286, 2007.
-
(2007)
Drug Discovery
, vol.6
, pp. 273-286
-
-
Folkman, J.1
-
50
-
-
0033573895
-
VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases
-
Doanes AM, Hegland DD, Sethi R, Kovesdi I, Bruder JT and Finkel T: VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases. Biochem Bioph Res Commun 255: 545-548, 1999.
-
(1999)
Biochem Bioph Res Commun
, vol.255
, pp. 545-548
-
-
Doanes, A.M.1
Hegland, D.D.2
Sethi, R.3
Kovesdi, I.4
Bruder, J.T.5
Finkel, T.6
-
51
-
-
0035966004
-
Vascular endothelial growth factor induction of the angiogenic phenotype requires RAS activation
-
Meadows KN, Bryant P and Pumiglia K: Vascular endothelial growth factor induction of the angiogenic phenotype requires RAS activation. J Biol Chem 276: 49289-49298, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 49289-49298
-
-
Meadows, K.N.1
Bryant, P.2
Pumiglia, K.3
-
52
-
-
30944440262
-
Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF)
-
Byrne AM, Bouchier-Hayes DJ and Harmey JH: Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). J Cell Mol Med 9: 777-794.
-
J Cell Mol Med
, vol.9
, pp. 777-794
-
-
Byrne, A.M.1
Bouchier-Hayes, D.J.2
Harmey, J.H.3
-
53
-
-
70449646016
-
Hypoxia enhances FGF-2 and VEGF stimulated human placental artery endothelial cell proliferation: Roles of MEK-1/2/ERK1-2 and PI3K/AKT1 pathways
-
Wang K, Jiang YZ, Chen DB and Zheng J: Hypoxia enhances FGF-2 and VEGF stimulated human placental artery endothelial cell proliferation: roles of MEK-1/2/ERK1-2 and PI3K/AKT1 pathways. Placenta 30: 1045-1051.
-
Placenta
, vol.30
, pp. 1045-1051
-
-
Wang, K.1
Jiang, Y.Z.2
Chen, D.B.3
Zheng, J.4
-
54
-
-
0033558798
-
VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MNAPK/ERK and SAPK/JNK signaling
-
Gupta I, Kshirsagar S, Li W, Gui L, Ramakrishnan S, Gupta P, Law PW and Hebbel SP: VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MNAPK/ERK and SAPK/JNK signaling. Exp Cell Res 247: 495-504, 1999.
-
(1999)
Exp Cell Res
, vol.247
, pp. 495-504
-
-
Gupta, I.1
Kshirsagar, S.2
Li, W.3
Gui, L.4
Ramakrishnan, S.5
Gupta, P.6
Law, P.W.7
Hebbel, S.P.8
-
55
-
-
0037235049
-
VEGF increases endothelial permeability by separate signaling pathways involving ERK-1/2 and nitric oxide
-
Breslin JW, Pappas PJ, Cerveira JJ, Hobson RW II and Duran WN: VEGF increases endothelial permeability by separate signaling pathways involving ERK-1/2 and nitric oxide. Am J Physiol 284: H92-H100, 2003.
-
(2003)
Am J Physiol
, vol.284
, pp. H92-H100
-
-
Breslin, J.W.1
Pappas, P.J.2
Cerveira, J.J.3
Hobson, R.W.4
Duran, W.N.5
-
56
-
-
0034000699
-
VEGF receptor signaling in tumor angiogenesis
-
McMahon G: VEGF receptor signaling in tumor angiogenesis. Oncologist 5: S3-S10, 2000.
-
(2000)
Oncologist
, vol.5
, pp. S3-S10
-
-
McMahon, G.1
-
57
-
-
84866275052
-
Novel dual inhibitors of vascular endothelial growth factor and the VEGFR2 Receptor
-
Nguyen JP, Frost CD, Lane ML, Skelton WR IV, Skelton M and Vesely DL: Novel dual inhibitors of vascular endothelial growth factor and the VEGFR2 Receptor. Eur J Clin Invest 42: 1061-1067, 2012.
-
(2012)
Eur J Clin Invest
, vol.42
, pp. 1061-1067
-
-
Nguyen, J.P.1
Frost, C.D.2
Lane, M.L.3
Skelton, W.R.4
Skelton, M.5
Vesely, D.L.6
-
58
-
-
0035882030
-
Regulation of vascular endothelial growth factor by the WNT and KRAS pathways in colonic neoplasia
-
Zhang X, Gaspard JP and Chung DC: Regulation of vascular endothelial growth factor by the WNT and KRAS pathways in colonic neoplasia. Cancer Res 61: 6050-6054, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 6050-6054
-
-
Zhang, X.1
Gaspard, J.P.2
Chung, D.C.3
-
59
-
-
0038133109
-
Gene expression patterns in pancreatic tumor, cells and tissues
-
Lowe AW, Olsen M, Hao Y, Lee SP, Lee KT, Chen X, Vanderijn M and Brown PO: Gene expression patterns in pancreatic tumor, cells and tissues. Ann Surg Oncol 10: 284-290, 2003.
-
(2003)
Ann Surg Oncol
, vol.10
, pp. 284-290
-
-
Lowe, A.W.1
Olsen, M.2
Hao, Y.3
Lee, S.P.4
Lee, K.T.5
Chen, X.6
Vanderijn, M.7
Brown, P.O.8
-
60
-
-
53049110158
-
Stabilization of β-catenin induces pancreas tumor formation
-
Heiser PW, Cano DA, Landsman L, Kim GE, Kench JG, Klimstra DS, Taketo MM, Biankin AV and Hebrok M: Stabilization of β-Catenin induces pancreas tumor formation. Gastroenterology 135: 1288-1300, 2008.
-
(2008)
Gastroenterology
, vol.135
, pp. 1288-1300
-
-
Heiser, P.W.1
Cano, D.A.2
Landsman, L.3
Kim, G.E.4
Kench, J.G.5
Klimstra, D.S.6
Taketo, M.M.7
Biankin, A.V.8
Hebrok, M.9
-
61
-
-
0033565255
-
β-Catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway
-
Mirabelli-Primidahl L, Gryfe R, Kim H, Millar A, Luceri C, Dale D, Holowaty E, Bayat D, Gallinger S and Redston M: β-Catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway. Cancer Res 59: 3346-3351, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 3346-3351
-
-
Mirabelli-Primidahl, L.1
Gryfe, R.2
Kim, H.3
Millar, A.4
Luceri, C.5
Dale, D.6
Holowaty, E.7
Bayat, D.8
Gallinger, S.9
Redston, M.10
-
62
-
-
0033974988
-
Altered expression of β-catenin in renal cell cancer and transitional cell cancer with the absence of β-catenin gene mutations
-
Bilim V, Kawasaki T, Katagiri A, Wakatsuki S, Takahashi JK and Tomita Y: Altered expression of β-Catenin in renal cell cancer and transitional cell cancer with the absence of β-Catenin gene mutations. Clin Cancer Res 6: 460-466, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 460-466
-
-
Bilim, V.1
Kawasaki, T.2
Katagiri, A.3
Wakatsuki, S.4
Takahashi, J.K.5
Tomita, Y.6
-
63
-
-
0033677022
-
Frequent association of β-catenin and WTI mutations in Wilms tumors
-
Maiti S, Alam R, Amos CI and Huff V: Frequent association of β-catenin and WTI mutations in Wilms tumors. Cancer Res 60: 6288-6292, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 6288-6292
-
-
Maiti, S.1
Alam, R.2
Amos, C.I.3
Huff, V.4
-
64
-
-
0038135028
-
Loss of β-catenin expression in metastatic gastric cancer
-
Ebert MPA, Yu J, Hoffman J, Rocco A, Rocken C, Kahmann S, Muller O, Korc M, Sung JJ and Malftheiner P: Loss of β-Catenin expression in metastatic gastric cancer. J Clin Oncol 2003: 1708-1714, 2003.
-
(2003)
J Clin Oncol
, vol.2003
, pp. 1708-1714
-
-
Ebert, M.P.A.1
Yu, J.2
Hoffman, J.3
Rocco, A.4
Rocken, C.5
Kahmann, S.6
Muller, O.7
Korc, M.8
Sung, J.J.9
Malftheiner, P.10
-
65
-
-
0034636153
-
β-catenin is a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
-
Lin SY, Xia W, Wang JC, Kwong KY, Spohn B, Wen Y, Pestell RG and Hung MC: β-catenin is a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA 97: 4262-4266, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4262-4266
-
-
Lin, S.Y.1
Xia, W.2
Wang, J.C.3
Kwong, K.Y.4
Spohn, B.5
Wen, Y.6
Pestell, R.G.7
Hung, M.C.8
-
66
-
-
79551624262
-
β-Catenin pathway activation in breast cancer is associated with triplenegative phenotype but not with CTNNB1 mutation
-
Geyer FC, Lacrois-Triki M, Savage K, Arnedos M, Lambros MB, MacKay A, Natrajan R and Reis-Filho JS: β-Catenin pathway activation in breast cancer is associated with triplenegative phenotype but not with CTNNB1 mutation. Modern Pathol 24: 209-231, 2010.
-
(2010)
Modern Pathol
, vol.24
, pp. 209-231
-
-
Geyer, F.C.1
Lacrois-Triki, M.2
Savage, K.3
Arnedos, M.4
Lambros, M.B.5
MacKay, A.6
Natrajan, R.7
Reis-Filho, J.S.8
-
67
-
-
34248674146
-
WNT/β-catenin signaling in liver health and disease
-
Thompson MD and Monga SPS: WNT/β-Catenin signaling in liver health and disease. Hepatology 45: 1298-1305, 2007.
-
(2007)
Hepatology
, vol.45
, pp. 1298-1305
-
-
Thompson, M.D.1
Monga, S.P.S.2
-
68
-
-
0033486152
-
β-Catenin signaling and cancer
-
Morin PJ: β-Catenin signaling and cancer. BioEssays 21: 1021-1030, 1999.
-
(1999)
Bioessays
, vol.21
, pp. 1021-1030
-
-
Morin, P.J.1
-
69
-
-
0033561515
-
Frequent mutation and nuclear localization of β-catenin in anaplastic thyroid carcinoma
-
Garcia-Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangui ML and Rimm DL: Frequent mutation and nuclear localization of β-Catenin in anaplastic thyroid carcinoma. Cancer Res 59: 1811-1815, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 1811-1815
-
-
Garcia-Rostan, G.1
Tallini, G.2
Herrero, A.3
D'Aquila, T.G.4
Carcangui, M.L.5
Rimm, D.L.6
-
70
-
-
22244457075
-
Multiple signaling pathways converge on β-catenin in thyroid cancer
-
Abbosh PH and Nephew KP: Multiple signaling pathways converge on β-Catenin in thyroid cancer. Thyroid 15: 551-560, 2005.
-
(2005)
Thyroid
, vol.15
, pp. 551-560
-
-
Abbosh, P.H.1
Nephew, K.P.2
-
71
-
-
2642673582
-
β-Catenin mutations in human prostate cancer
-
Voeller JH, Trucia CI and Gelmann EP: β-Catenin mutations in human prostate cancer. Cancer Res 58: 2520-2523, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 2520-2523
-
-
Voeller, J.H.1
Trucia, C.I.2
Gelmann, E.P.3
-
72
-
-
0347087570
-
β-Catenin signaling prostate cancer: An early perspective
-
Cheshire DR and Isaacs WB: β-Catenin signaling prostate cancer: an early perspective. Endocr-Relat Cancer 10: 537-560, 2003.
-
(2003)
Endocr-Relat Cancer
, vol.10
, pp. 537-560
-
-
Cheshire, D.R.1
Isaacs, W.B.2
-
73
-
-
84881361685
-
Role of β-Catenin in the anticancer effects of cardiac hormones
-
Skelton WP, Skelton M and Vesely DL: Role of β-Catenin in the anticancer effects of cardiac hormones. Anticancer Res 33: 2409-2414, 2013.
-
(2013)
Anticancer Res
, vol.33
, pp. 2409-2414
-
-
Skelton, W.P.1
Skelton, M.2
Vesely, D.L.3
-
74
-
-
84859027559
-
Antiproliferative effect of atrial natriuretic peptide on colorectal cancer cells: Evidence for an Akt-mediated cross-talk between NHE-1 activity and WNT/β-catenin signaling
-
Serafino A, Moroni N, Psaila R, Zonfrillo M, Andreola F, Wannenes F, Mercuri L, Rasi G and Pierimarchi P: Antiproliferative effect of atrial natriuretic peptide on colorectal cancer cells: Evidence for an Akt-mediated cross-talk between NHE-1 activity and WNT/β-Catenin signaling. Biochim Biophys Acta 1822: 1004-1018, 2012.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 1004-1018
-
-
Serafino, A.1
Moroni, N.2
Psaila, R.3
Zonfrillo, M.4
Andreola, F.5
Wannenes, F.6
Mercuri, L.7
Rasi, G.8
Pierimarchi, P.9
-
75
-
-
13044281685
-
Target genes of β-catenin-T cell factor/lymphoid-enhancer factor signaling in human colorectal carcinomas
-
Mann B, Gelos M, Siedow A, Hanski ML, Gratchev A, Ilyas M, Bodmer WF, Moyer MP, Riecken EO, Burh HJ and Hanski C: Target genes of β-Catenin-T cell factor/lymphoid-enhancer factor signaling in human colorectal carcinomas. Proc Natl Acad Sci USA 96: 1603-1608, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1603-1608
-
-
Mann, B.1
Gelos, M.2
Siedow, A.3
Hanski, M.L.4
Gratchev, A.5
Ilyas, M.6
Bodmer, W.F.7
Moyer, M.P.8
Riecken, E.O.9
Burh, H.J.10
Hanski, C.11
-
76
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer. Nature reviews
-
Vivanco I and Sawyers CL: The phosphatidylinositol 3-kinase-AKT pathway in human cancer. Nature Reviews. Cancer 2: 489-501, 2002.
-
(2002)
Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
77
-
-
27844445642
-
Perturbations of the AKT signaling pathway in human cancer. Nature reviews
-
Altomare DA and Testa JR: Perturbations of the AKT signaling pathway in human cancer. Nature Reviews. Cancer 24: 7455-7464, 2005.
-
(2005)
Cancer
, vol.24
, pp. 7455-7464
-
-
Altomare, D.A.1
Testa, J.R.2
-
78
-
-
24944480788
-
The AKT-mTOR tango and its relevance to cancer
-
Hay N: The AKT-mTOR tango and its relevance to cancer. Cancer Cell 8: 179-183, 2005.
-
(2005)
Cancer Cell
, vol.8
, pp. 179-183
-
-
Hay, N.1
-
79
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy GT, Smith DL, Ram PT, Lu Y and Mills GB: Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat Rev. Drug Discovery 4: 988-1004, 2005.
-
(2005)
Nat Rev. Drug Discovery
, vol.4
, pp. 988-1004
-
-
Hennessy, G.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
80
-
-
33745307617
-
Ras, PI(3)K and mTOR signaling controls tumor cell growth
-
Shaw RJ and Cantley LC: Ras, PI(3)K and mTOR signaling controls tumor cell growth. Nature 441: 424-430, 2006.
-
(2006)
Nature
, vol.441
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
81
-
-
0017647580
-
Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma
-
Staal SP, Hartley JW and Rowe SP: Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma. Proc Natl Acad Sci USA 74: 3065-3067.
-
Proc Natl Acad Sci USA
, vol.74
, pp. 3065-3067
-
-
Staal, S.P.1
Hartley, J.W.2
Rowe, S.P.3
-
82
-
-
0036195196
-
AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis
-
Roy HK, Olusola BF, Clemens DL, Karolski WJ, Ratashak A, Lynch HT and Smyrk TC: AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis. Carcinogenesis 23: 201-205, 2002.
-
(2002)
Carcinogenesis
, vol.23
, pp. 201-205
-
-
Roy, H.K.1
Olusola, B.F.2
Clemens, D.L.3
Karolski, W.J.4
Ratashak, A.5
Lynch, H.T.6
Smyrk, T.C.7
-
83
-
-
84875904511
-
Inhibition of Akt in human pancreatic, renal and colorectal cancer cells by four cardiac hormones
-
Skelton WP IV, Skelton M and Vesely DL: Inhibition of Akt in human pancreatic, renal and colorectal cancer cells by four cardiac hormones. Anticancer Res 33: 785-790, 2013.
-
(2013)
Anticancer Res
, vol.33
, pp. 785-790
-
-
Skelton, W.P.1
Skelton, M.2
Vesely, D.L.3
-
84
-
-
34548079500
-
Targeting the AKT protein kinase for cancer chemoprevention
-
Crowell JA, Steele VE and Fay JR: Targeting the AKT protein kinase for cancer chemoprevention. Mol Cancer Therap 6: 2139-2148, 2007.
-
(2007)
Mol Cancer Therap
, vol.6
, pp. 2139-2148
-
-
Crowell, J.A.1
Steele, V.E.2
Fay, J.R.3
-
85
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/AKT signal transduction pathway: Requirement for FLK-1/KDR activation
-
Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V and Ferrara N: Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/AKT signal transduction pathway: requirement for FLK-1/KDR activation. J Biol Chem 273: 30336-30343, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
Yan, M.4
Keyt, B.A.5
Dixit, V.6
Ferrara, N.7
-
86
-
-
26444448463
-
The surval kinases AKT and Pim as potential pharmacological target
-
Amaravadi R and Thomopson CB: The surval kinases AKT and Pim as potential pharmacological target. J Clin Invest 115: 2618-2624, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 2618-2624
-
-
Amaravadi, R.1
Thomopson, C.B.2
-
87
-
-
0030799081
-
The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of WNT signaling
-
Lin K, Wang S, Julius MA, Kitajewski J, Moos M Jr. and Luyten SP: The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of WNT signaling. Proc Natl Acad Sci USA 94: 11196-11200, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11196-11200
-
-
Lin, K.1
Wang, S.2
Julius, M.A.3
Kitajewski, J.4
Moos, M.5
Luyten, S.P.6
-
88
-
-
0030905162
-
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors
-
Rattner A, Hsieh JC, Smallwood PM, Gilbert DJ, Copeland NG, Jenkins NA and Nathans J: A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci USA 94: 2859-2863, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2859-2863
-
-
Rattner, A.1
Hsieh, J.C.2
Smallwood, P.M.3
Gilbert, D.J.4
Copeland, N.G.5
Jenkins, N.A.6
Nathans, J.7
-
89
-
-
0035811492
-
Insights into WNT binding and signaling from the structures of two frizzled cysteine-rich domains
-
Dann CE, Hsieh JC, Rattner A, Sharma D, Nathans J and Leahy DJ: Insights into WNT binding and signaling from the structures of two frizzled cysteine-rich domains. Nature 412: 86-90, 2001.
-
(2001)
Nature
, vol.412
, pp. 86-90
-
-
Dann, C.E.1
Hsieh, J.C.2
Rattner, A.3
Sharma, D.4
Nathans, J.5
Leahy, D.J.6
-
90
-
-
2442708165
-
Frizzleds: New members of the superfamily of G-protein-coupled receptors
-
Malbon CC: Frizzleds: New members of the superfamily of G-protein-coupled receptors. Frontiers in Bioscience 9: 1048-1058, 2004.
-
(2004)
Frontiers in Bioscience
, vol.9
, pp. 1048-1058
-
-
Malbon, C.C.1
-
91
-
-
77950190313
-
Role of secreted frizzled-related protein 3 in human renal cell carcinoma
-
Hirata H, Hinoda Y, Ueno K, Majid S, Saini S and Dahiya R: Role of secreted frizzled-related protein 3 in human renal cell carcinoma. Cancer Res 70: 1896-1905, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 1896-1905
-
-
Hirata, H.1
Hinoda, Y.2
Ueno, K.3
Majid, S.4
Saini, S.5
Dahiya, R.6
-
93
-
-
0032482447
-
The frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases
-
Xu YK and Nusse R: The frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases. Current Biol 8: R405-R406, 1998.
-
(1998)
Current Biol
, vol.8
, pp. R405-R406
-
-
Xu, Y.K.1
Nusse, R.2
-
94
-
-
0038783316
-
Secreted antagonists of the WNT signalling pathway
-
Kawano Y and Kypta R: Secreted antagonists of the WNT signalling pathway. J Cell Sci 116: 2627-2634, 2003.
-
(2003)
J Cell Sci
, vol.116
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
95
-
-
84871355882
-
Cardiac hormones are potent inhibitors of secreted Frizzled related protein-3 in human cancer cells
-
Skelton WP IV, Skelton M and Vesely DL: Cardiac hormones are potent inhibitors of secreted Frizzled related protein-3 in human cancer cells. Exp Ther Med 5: 475-478, 2013.
-
(2013)
Exp Ther Med
, vol.5
, pp. 475-478
-
-
Skelton, W.P.1
Skelton, M.2
Vesely, D.L.3
-
96
-
-
0026770248
-
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
-
Schindler C, Shuai K, Prezioso VR and Darnell JE Jr.: Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257: 809-813, 1992.
-
(1992)
Science
, vol.257
, pp. 809-813
-
-
Schindler, C.1
Shuai, K.2
Prezioso, V.R.3
Darnell, J.E.4
-
97
-
-
1042302005
-
The STATs of cancer: New molecular targets come of age. Nature reviews
-
Yu H and Jove R: The STATs of cancer: New molecular targets come of age. Nature Reviews. Cancer 4: 450-456, 2004.
-
(2004)
Cancer
, vol.4
, pp. 450-456
-
-
Yu, H.1
Jove, R.2
-
98
-
-
0036782706
-
Transcription factors as targets for cancer therapy. Nature reviews
-
Darnell JR Jr.,: Transcription factors as targets for cancer therapy. Nature Reviews. Cancer 2: 740-749, 2002.
-
(2002)
Cancer
, vol.2
, pp. 740-749
-
-
Darnell, J.R.1
-
99
-
-
0034657336
-
The role of STATs in transcriptional control and their impact on cellular function
-
Bromberg J and Darnell JE Jr.: The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19: 2468-2473, 2002.
-
(2002)
Oncogene
, vol.19
, pp. 2468-2473
-
-
Bromberg, J.1
Darnell, J.E.2
-
100
-
-
0013689209
-
Requirement of STAT3 but not STAT1 activation for epidermal growth factor receptor-mediated cell growth in vitro
-
Grandis J, Drenning SD, Chakraborty A, Zhou MY, Zeng Q, Pitt AS and Tweardy DJ: Requirement of STAT3 but not STAT1 activation for epidermal growth factor receptor-mediated cell growth in vitro. J Clin Invest 102: 1385-1392, 1998.
-
(1998)
J Clin Invest
, vol.102
, pp. 1385-1392
-
-
Grandis, J.1
Drenning, S.D.2
Chakraborty, A.3
Zhou, M.Y.4
Zeng, Q.5
Pitt, A.S.6
Tweardy, D.J.7
-
101
-
-
0037699512
-
Activation of STAT3 by receptor tyrosine kinases and cytokinases regulates survival in human non-small-cell carcinoma cells
-
Song L, Turkson J, Karras JG, Jove R and Haura EG: Activation of STAT3 by receptor tyrosine kinases and cytokinases regulates survival in human non-small-cell carcinoma cells. Oncogene 22: 4150-4165, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 4150-4165
-
-
Song, L.1
Turkson, J.2
Karras, J.G.3
Jove, R.4
Haura, E.G.5
-
102
-
-
0030772458
-
STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
-
Chung J, Uchida E, Grammer TC and Blenis J: STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. Mol Cell Biol 17: 6508-6516, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6508-6516
-
-
Chung, J.1
Uchida, E.2
Grammer, T.C.3
Blenis, J.4
-
103
-
-
84868519982
-
Potent selective inhibition of STAT3 versus STAT1 by cardiac hormones
-
Lane ML, Frost CD, Nguyen JP, Skelton WP IV, Skelton M and Vesely DL: Potent selective inhibition of STAT3 versus STAT1 by cardiac hormones. Mol Cell Biochem 371: 209-215, 2012.
-
(2012)
Mol Cell Biochem
, vol.371
, pp. 209-215
-
-
Lane, M.L.1
Frost, C.D.2
Nguyen, J.P.3
Skelton, W.P.4
Skelton, M.5
Vesely, D.L.6
-
104
-
-
0021752840
-
Induction of c-FOS gene and protein by growth factors precedes activation of c-Myc
-
Muller R, Bravo R, Burckhardt J and Curran T: Induction of c-FOS gene and protein by growth factors precedes activation of c-Myc. Nature 312: 716-720, 1984.
-
(1984)
Nature
, vol.312
, pp. 716-720
-
-
Muller, R.1
Bravo, R.2
Burckhardt, J.3
Curran, T.4
-
105
-
-
0035971493
-
AP-1 in cell proliferation and survival
-
Shaulian E and Karin M: AP-1 in cell proliferation and survival. Oncogene 20: 2390-2400, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 2390-2400
-
-
Shaulian, E.1
Karin, M.2
-
106
-
-
0026095599
-
Epidermal growth factor and transforming growth factor α induce c-FOS gene expression in retinal Muller cells in vivo
-
Sagar S, Edwards R and Sharp F: Epidermal growth factor and transforming growth factor α induce c-FOS gene expression in retinal Muller cells in vivo. J Neurosci Res 29: 549-559, 1991.
-
(1991)
J Neurosci Res
, vol.29
, pp. 549-559
-
-
Sagar, S.1
Edwards, R.2
Sharp, F.3
-
107
-
-
61849085224
-
c-FOS overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin-D1
-
Guller M, Toualbi-Abed K, Legand A, Michel L, Mauviel A, Bernuau D and Daniel F: c-FOS overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin-D1. World J Gastroenterol 14: 6339-6346, 2008.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 6339-6346
-
-
Guller, M.1
Toualbi-Abed, K.2
Legand, A.3
Michel, L.4
Mauviel, A.5
Bernuau, D.6
Daniel, F.7
-
108
-
-
0025773533
-
c-FOS and c-Myc oncoprotein expression in human hepatocellular carcinomas
-
Arbuthnot P, Kew M and Fitschen W: c-FOS and c-Myc oncoprotein expression in human hepatocellular carcinomas. Anticancer Res 11: 921-924, 1991.
-
(1991)
Anticancer Res
, vol.11
, pp. 921-924
-
-
Arbuthnot, P.1
Kew, M.2
Fitschen, W.3
-
109
-
-
16244407731
-
Epidermal growth factor-induced hepatocellular carcinoma: Gene expression profiles in precursor lesions, early stage and solitary tumours
-
Bolak J, Meier T, Halter R, Spanel R and Spanel-Borowski K: Epidermal growth factor-induced hepatocellular carcinoma: Gene expression profiles in precursor lesions, early stage and solitary tumours. Oncogene 24: 1809-1819, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 1809-1819
-
-
Bolak, J.1
Meier, T.2
Halter, R.3
Spanel, R.4
Spanel-Borowski, K.5
-
110
-
-
0035173815
-
Expression of c-Myc, c-FOS and c-JUN in hepatocellular carcinoma
-
Yuen MF, Wu PC, Lau JYN and Lai CL: Expression of c-Myc, c-FOS and c-JUN in hepatocellular carcinoma. Cancer 91: 106-112, 2001.
-
(2001)
Cancer
, vol.91
, pp. 106-112
-
-
Yuen, M.F.1
Wu, P.C.2
Lau, J.Y.N.3
Lai, C.L.4
-
111
-
-
0023771685
-
c-JUN dimerizes with itself and c-FOS, forming complexes of different DNA-binding proteins
-
Halazonetis TD, Georgopoulos K, Greenberg ME and Leder P: c-JUN dimerizes with itself and c-FOS, forming complexes of different DNA-binding proteins. Cell 55: 917-924, 1988.
-
(1988)
Cell
, vol.55
, pp. 917-924
-
-
Halazonetis, T.D.1
Georgopoulos, K.2
Greenberg, M.E.3
Leder, P.4
-
112
-
-
0023909745
-
Fos-associated protein p39 is the product of the jun proto-oncogene
-
Rauscher F, Cohen D, Curran T, Bos T, Vogt P, Bohmann D, Tijan R and Franza BR Jr.: Fos-associated protein p39 is the product of the jun proto-oncogene. Science 240: 1010-1016, 1988.
-
(1988)
Science
, vol.240
, pp. 1010-1016
-
-
Rauscher, F.1
Cohen, D.2
Curran, T.3
Bos, T.4
Vogt, P.5
Bohmann, D.6
Tijan, R.7
Franza, B.R.8
-
113
-
-
27444440554
-
Regulation of the transcriptional activity of c-FOS by ERK. A novel role for the prolyl isomerase PIN1
-
Monje P, Hernandez-Losa J, Lyons RJ, Castellone MD and Gutkind JS: Regulation of the transcriptional activity of c-FOS by ERK. A novel role for the prolyl isomerase PIN1. J Biol Chem 280: 35081-35084, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 35081-35084
-
-
Monje, P.1
Hernandez-Losa, J.2
Lyons, R.J.3
Castellone, M.D.4
Gutkind, J.S.5
-
114
-
-
0035113393
-
Effect of phosphorylation of MAPK and STAT-3 and expression of c-FOS and c-JUN proteins on hepatocarcinogenesis and their clinical significance
-
Feng DY, Zheng H, Tan Y and Cheng RX: Effect of phosphorylation of MAPK and STAT-3 and expression of c-FOS and c-JUN proteins on hepatocarcinogenesis and their clinical significance. World J Gastroenterol 7: 33-36, 2001.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 33-36
-
-
Feng, D.Y.1
Zheng, H.2
Tan, Y.3
Cheng, R.X.4
-
115
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-JUN activation domain
-
Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M and Davis RJ: JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-JUN activation domain. Cell 76: 1025-1037, 1994.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
116
-
-
0032845125
-
Interacting regions in STAT-3 and c-JUN that participate in cooperative transcriptional activation
-
Zhang X, Wrzeszczynska MH, Horvath CM and Darnell JE: Interacting regions in STAT-3 and c-JUN that participate in cooperative transcriptional activation. Mol Cell Biol 19: 7138-7146, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7138-7146
-
-
Zhang, X.1
Wrzeszczynska, M.H.2
Horvath, C.M.3
Darnell, J.E.4
-
117
-
-
22944438049
-
Immunocytochemical localization of atrial natriuretic peptide, vessel dilator, long-acting natriuretic peptide, and kaliuretic peptide in human pancreatic adenocarcinomas
-
Saba SR, Garces AH, Clark LC, Soto J, Gower WR Jr., and Vesely DL: Immunocytochemical localization of atrial natriuretic peptide, vessel dilator, long-acting natriuretic peptide, and kaliuretic peptide in human pancreatic adenocarcinomas. J Histochem Cytochem 53: 989-995, 2005.
-
(2005)
J Histochem Cytochem
, vol.53
, pp. 989-995
-
-
Saba, S.R.1
Garces, A.H.2
Clark, L.C.3
Soto, J.4
Gower, W.R.5
Vesely, D.L.6
-
118
-
-
33645774369
-
Cardiac natriuretic peptides: Hormones with anticancer effects that localize to nucleus, cytoplasm, endothelium and fibroblasts of human cancers
-
Saba SR and Vesely DL: Cardiac natriuretic peptides: Hormones with anticancer effects that localize to nucleus, cytoplasm, endothelium and fibroblasts of human cancers. Histol Histopath 21: 775-783, 2006.
-
(2006)
Histol Histopath
, vol.21
, pp. 775-783
-
-
Saba, S.R.1
Vesely, D.L.2
-
119
-
-
84885428655
-
Anticancer peptides from the heart target c-JUN and c-FOS in hepatocellular, small-cell lung and renal carcinomas
-
Manimala NJ, Frost CD, Lane ML, Higuera M, Beg R and Vesely DL: Anticancer peptides from the heart target c-JUN and c-FOS in hepatocellular, small-cell lung and renal carcinomas. Eur J Clin Invest 43: 1156-1162, 2013.
-
(2013)
Eur J Clin Invest
, vol.43
, pp. 1156-1162
-
-
Manimala, N.J.1
Frost, C.D.2
Lane, M.L.3
Higuera, M.4
Beg, R.5
Vesely, D.L.6
-
120
-
-
77951218958
-
Epidermal growth factor's activation of Ras is inhibited by four cardiac hormones
-
Sun Y, Eichelbaum EJ, Lenz A, Wang H and Vesely DL: Epidermal growth factor's activation of Ras is inhibited by four cardiac hormones. Eur J Clin Invest 40: 408-413, 2010.
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 408-413
-
-
Sun, Y.1
Eichelbaum, E.J.2
Lenz, A.3
Wang, H.4
Vesely, D.L.5
|