메뉴 건너뛰기




Volumn 33, Issue 22, 2014, Pages 2857-2865

Ras signaling is essential for skin development

Author keywords

epidermis; hair follicles; keratinocytes; Ras signaling; senescence

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A;

EID: 84901849404     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.254     Document Type: Article
Times cited : (36)

References (52)
  • 1
    • 80051983081 scopus 로고    scopus 로고
    • Deconstructing the skin: Cytoarchitectural determinants of epidermal morphogenesis
    • Simpson CL, Patel DM, Green KJ. Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis. Nat Rev Mol Cell Biol 2011; 12: 565-580.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 565-580
    • Simpson, C.L.1    Patel, D.M.2    Green, K.J.3
  • 2
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal homeostasis: A balancing act of stem cells in the skin
    • Blanpain C, Fuchs E. Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 2009; 10: 207-217.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 3
    • 38449101897 scopus 로고    scopus 로고
    • Mechanisms regulating epithelial stratification
    • Koster MI, Roop DR. Mechanisms regulating epithelial stratification. Annu Rev Cell Dev Biol 2007; 23: 93-113.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 93-113
    • Koster, M.I.1    Roop, D.R.2
  • 4
    • 68649118611 scopus 로고    scopus 로고
    • Making an epidermis
    • Koster MI. Making an epidermis. Ann N Y Acad Sci 2009; 1170: 7-10.
    • (2009) Ann N y Acad Sci , vol.1170 , pp. 7-10
    • Koster, M.I.1
  • 5
    • 0028025616 scopus 로고
    • Programming gene expression in developing epidermis
    • Byrne C, Tainsky M, Fuchs E. Programming gene expression in developing epidermis. Development 1994; 120: 2369-2383. (Pubitemid 24268813)
    • (1994) Development , vol.120 , Issue.9 , pp. 2369-2383
    • Byrne, C.1    Tainsky, M.2    Fuchs, E.3
  • 6
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • DOI 10.1038/nature03922
    • Lechler T, Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 2005; 437: 275-280. (Pubitemid 41294492)
    • (2005) Nature , vol.437 , Issue.7056 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 7
    • 0025679060 scopus 로고
    • Epidermal differentiation: The bare essentials
    • Fuchs E. Epidermal differentiation: the bare essentials. J Cell Biol 1990; 111: 2807-2814. (Pubitemid 120034022)
    • (1990) Journal of Cell Biology , vol.111 , Issue.6 PART 2 , pp. 2807-2814
    • Fuchs, E.1
  • 8
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: A model of cell death in the skin
    • DOI 10.1038/nrm1619
    • Candi E, Schmidt R, Melino G. The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 2005; 6: 328-340. (Pubitemid 40516899)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.4 , pp. 328-340
    • Candi, E.1    Schmidt, R.2    Melino, G.3
  • 9
    • 0036178229 scopus 로고    scopus 로고
    • Molecular mechanisms regulating hair follicle development
    • DOI 10.1046/j.0022-202x.2001.01670.x
    • Millar SE. Molecular mechanisms regulating hair follicle development. J Invest Dermatol 2002; 118: 216-225. (Pubitemid 34158473)
    • (2002) Journal of Investigative Dermatology , vol.118 , Issue.2 , pp. 216-225
    • Millar, S.E.1
  • 10
    • 84868455051 scopus 로고    scopus 로고
    • Hairy tale of signaling in hair follicle development and cycling
    • Lee J, Tumbar T. Hairy tale of signaling in hair follicle development and cycling. Semin Cell Dev Biol 2012; 23: 906-916.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 906-916
    • Lee, J.1    Tumbar, T.2
  • 11
    • 33847235717 scopus 로고    scopus 로고
    • Scratching the surface of skin development
    • Fuchs E. Scratching the surface of skin development. Nature 2007; 445: 834-842.
    • (2007) Nature , vol.445 , pp. 834-842
    • Fuchs, E.1
  • 12
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • DOI 10.1038/nrc1097
    • Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer 2003; 3: 459-465. (Pubitemid 37328850)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 14
    • 84859967413 scopus 로고    scopus 로고
    • The Ras protein superfamily: Evolutionary tree and role of conserved amino acids
    • Rojas AM, Fuentes G, Raussell A, Valencia A. The Ras protein superfamily: evolutionary tree and role of conserved amino acids. J Cell Biol 2012; 196: 189-201.
    • (2012) J Cell Biol , vol.196 , pp. 189-201
    • Rojas, A.M.1    Fuentes, G.2    Raussell, A.3    Valencia, A.4
  • 16
    • 77949568748 scopus 로고    scopus 로고
    • Genetic analysis of Ras signaling pathways in cell proliferation, migration and survival
    • Drosten M, Dhawahir A, Sum EYM, Urosevic J, Lechuga CG, Esteban LM et al. Genetic analysis of Ras signaling pathways in cell proliferation, migration and survival. EMBO J 2010; 29: 1091-1104.
    • (2010) EMBO J , vol.29 , pp. 1091-1104
    • Drosten, M.1    Dhawahir, A.2    Eym, S.3    Urosevic, J.4    Lechuga, C.G.5    Esteban, L.M.6
  • 17
    • 85047698904 scopus 로고    scopus 로고
    • Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation
    • DOI 10.1038/sj/onc/1205287
    • Dajee M, Tarutani M, Deng H, Cai T, Khavari PA. Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation. Oncogene 2002; 21: 1527-1538. (Pubitemid 34226140)
    • (2002) Oncogene , vol.21 , Issue.10 , pp. 1527-1538
    • Dajee, M.1    Tarutani, M.2    Deng, H.3    Cai, T.4    Khavari, P.A.5
  • 19
    • 0029045856 scopus 로고
    • Strain-dependent epithelial defects in mice lacking the EGF receptor
    • Sibilia M, Wagner EF. Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 1995; 269: 234-238.
    • (1995) Science , vol.269 , pp. 234-238
    • Sibilia, M.1    Wagner, E.F.2
  • 20
    • 0029064203 scopus 로고
    • Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
    • Threadgill DW, Dlugosz AA, Hansen LA, Tennenbaum T, Lichti U, Yee D et al. Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 1995; 269: 230-234.
    • (1995) Science , vol.269 , pp. 230-234
    • Threadgill, D.W.1    Dlugosz, A.A.2    Hansen, L.A.3    Tennenbaum, T.4    Lichti, U.5    Yee, D.6
  • 21
    • 0344445675 scopus 로고    scopus 로고
    • A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning
    • DOI 10.1242/dev.00788
    • Petiot A, Conti FJA, Grose R, Revest JM, Hodivala-Dilke KM, Dickson C. A crucial role for Fgfr2-IIIb signaling in epidermal development and hair follicle patterning. Development 2003; 130: 5493-5501. (Pubitemid 37484016)
    • (2003) Development , vol.130 , Issue.22 , pp. 5493-5501
    • Petiot, A.1    Conti, F.J.A.2    Grose, R.3    Revest, J.-M.4    Hodivala-Dilke, K.M.5    Dickson, C.6
  • 22
    • 77955942384 scopus 로고    scopus 로고
    • Functional proteomics to dissect tyrosine kinase signaling pathways in cancer
    • Kolch W, Pitt A. Functional proteomics to dissect tyrosine kinase signaling pathways in cancer. Nat Rev Cancer 2010; 10: 618-629.
    • (2010) Nat Rev Cancer , vol.10 , pp. 618-629
    • Kolch, W.1    Pitt, A.2
  • 23
    • 34047129136 scopus 로고    scopus 로고
    • Mek1/2 MAPK Kinases Are Essential for Mammalian Development, Homeostasis, and Raf-Induced Hyperplasia
    • DOI 10.1016/j.devcel.2007.03.009, PII S1534580707001098
    • Scholl FA, Dumesic PA, Barragan DI, Harada K, Bissonauth V, Charron J et al. Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia. Dev Cell 2007; 12: 615-629. (Pubitemid 46523646)
    • (2007) Developmental Cell , vol.12 , Issue.4 , pp. 615-629
    • Scholl, F.A.1    Dumesic, P.A.2    Barragan, D.I.3    Harada, K.4    Bissonauth, V.5    Charron, J.6    Khavari, P.A.7
  • 24
  • 25
    • 37549065911 scopus 로고    scopus 로고
    • Ras/Erk MAPK signaling in epidermal homeostasis and neoplasia
    • Khavari TA, Rinn J. Ras/Erk MAPK signaling in epidermal homeostasis and neoplasia. Cell Cycle 2007; 6: 2928-2931.
    • (2007) Cell Cycle , vol.6 , pp. 2928-2931
    • Khavari, T.A.1    Rinn, J.2
  • 26
    • 78751582082 scopus 로고    scopus 로고
    • Ras and Raf pathways in epidermis development
    • Kern F, Niault T, Baccarini M. Ras and Raf pathways in epidermis development. Br J Cancer 2011; 104: 229-234.
    • (2011) Br J Cancer , vol.104 , pp. 229-234
    • Kern, F.1    Niault, T.2    Baccarini, M.3
  • 28
    • 33751230475 scopus 로고    scopus 로고
    • P63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • Truong AB, Kretz M, Ridky TW, Kimmel R, Khavari PA. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev 2006; 20: 8723-8762.
    • (2006) Genes Dev , vol.20 , pp. 8723-8762
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3    Kimmel, R.4    Khavari, P.A.5
  • 30
    • 43149084824 scopus 로고    scopus 로고
    • Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice
    • DOI 10.1038/nprot.2008.50, PII NPROT.2008.50
    • Lichti U, Anders J, Yuspa SH. Isolation and short-term culture of primary kerati-nocytes, hair follicle populations and dermal cells from newborn mice and ker-atinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice. Nat Protocols 2008; 3: 799-810. (Pubitemid 351639024)
    • (2008) Nature Protocols , vol.3 , Issue.5 , pp. 799-810
    • Lichti, U.1    Anders, J.2    Yuspa, S.H.3
  • 31
    • 0033548592 scopus 로고    scopus 로고
    • Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum-and gluco-corticoid-inducible protein kinase, Sgk, in mammary tumor cells
    • Buse P, Tran SH, Luther E, Phu PT, Aponte GW, Firestone GL. Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum-and gluco-corticoid-inducible protein kinase, Sgk, in mammary tumor cells. J Biol Chem 1999; 274: 7253-7363.
    • (1999) J Biol Chem , vol.274 , pp. 7253-7363
    • Buse, P.1    Tran, S.H.2    Luther, E.3    Phu, P.T.4    Aponte, G.W.5    Firestone, G.L.6
  • 32
    • 33750030758 scopus 로고    scopus 로고
    • The Regulation of INK4/ARF in Cancer and Aging
    • DOI 10.1016/j.cell.2006.10.003, PII S0092867406012840
    • Kim WY, Sharpless NE. The regulation of INK4/ARF in cancer and aging. Cell 2006; 127: 265-275. (Pubitemid 44572384)
    • (2006) Cell , vol.127 , Issue.2 , pp. 265-275
    • Kim, W.Y.1    Sharpless, N.E.2
  • 33
    • 67649424560 scopus 로고    scopus 로고
    • P21 in cancer: Intricate networks and multiple activities
    • Abbas T, Dutta A. p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 2009; 9: 400-414.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 36
    • 0032523239 scopus 로고    scopus 로고
    • Inhibitory function of p21(Cip1/WAF1) in differentiation of primary mouse keratinocytes independent of cell cycle control
    • DOI 10.1126/science.280.5366.1069
    • Di Cunto F, Topley G, Calautti E, Hsiao J, Ong L, Seth PK et al. Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control. Science 1998; 280: 1069-1072. (Pubitemid 28234947)
    • (1998) Science , vol.280 , Issue.5366 , pp. 1069-1072
    • Di Cunto, F.1    Topley, G.2    Calautti, E.3    Hsiao, J.4    Ong, L.5    Seth, P.K.6    Dotto, G.P.7
  • 38
    • 42149123306 scopus 로고    scopus 로고
    • More than one way to skin..
    • DOI 10.1101/gad.1645908
    • Fuchs E, Horsley V. More than one way to the skin. Genes Dev 2008; 22: 976-985. (Pubitemid 351544236)
    • (2008) Genes and Development , vol.22 , Issue.8 , pp. 976-985
    • Fuchs, E.1    Horsley, V.2
  • 39
    • 10844223748 scopus 로고    scopus 로고
    • Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis
    • DOI 10.1158/0008-5472.CAN-04-2623
    • Vitale-Cross L, Amornphimoltham P, Fisher G, Molinolo AA, Gutkind JS. Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis. Cancer Res 2004; 64: 8804-8807. (Pubitemid 39665480)
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 8804-8807
    • Vitale-Cross, L.1    Amornphimoltham, P.2    Fisher, G.3    Molinolo, A.A.4    Gutkind, J.S.5
  • 40
    • 0034708781 scopus 로고    scopus 로고
    • The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking ras activation
    • DOI 10.1074/jbc.275.12.8854
    • Stewart S, Guan KL. The dominant-negative Ras mutant, N17Ras, can inhibit signaling independently of blocking Ras activation. J Biol Chem 2000; 275: 8854-8862. (Pubitemid 30180241)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.12 , pp. 8854-8862
    • Stewart, S.1    Guan, K.-L.2
  • 42
    • 0037439686 scopus 로고    scopus 로고
    • Inducible activation of Ras and Raf in adult epidermis
    • Tarutani M, Cai T, Dajee M, Khavari PA. Inducible activation of Ras and Raf in adult epidermis. Cancer Res 2003; 63: 319-323. (Pubitemid 36152487)
    • (2003) Cancer Research , vol.63 , Issue.2 , pp. 319-323
    • Tarutani, M.1    Cai, T.2    Dajee, M.3    Khavari, P.A.4
  • 43
    • 4344620189 scopus 로고    scopus 로고
    • Mek1 alters epidermal growth and differentiation
    • DOI 10.1158/0008-5472.CAN-04-0017
    • Scholl FA, Dumesic PA, Khavari PA. Mek1 alters epidermal growth and differentiation. Cancer Res 2004; 64: 6035-6040. (Pubitemid 39129401)
    • (2004) Cancer Research , vol.64 , Issue.17 , pp. 6035-6040
    • Scholl, F.A.1    Dumesic, P.A.2    Khavari, P.A.3
  • 44
    • 55549147132 scopus 로고    scopus 로고
    • The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b)
    • He J, Kallin EM, Tsukada Y, Zhang Y. The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b). Nat Struct Mol Biol 2008; 15: 1169-1175.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 1169-1175
    • He, J.1    Kallin, E.M.2    Tsukada, Y.3    Zhang, Y.4
  • 45
    • 0036371158 scopus 로고    scopus 로고
    • P21Waf1 control of epithelial cell cycle and cell fate
    • Weinberg WC, Denning MF. P21Waf1 control of epithelial cell cycle and cell fate. Crit Rev Oral Biol Med 2002; 13: 453-463.
    • (2002) Crit Rev Oral Biol Med , vol.13 , pp. 453-463
    • Weinberg, W.C.1    Denning, M.F.2
  • 46
    • 24344447780 scopus 로고    scopus 로고
    • P63 deficiency activates a program of cellular senescence and leads to accelerated aging
    • DOI 10.1101/gad.342305
    • Keyes WM, Wu Y, Vogel H, Guo X, Lows SW, Mills AA. p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev 2005; 19: 1986-1999. (Pubitemid 41247957)
    • (2005) Genes and Development , vol.19 , Issue.17 , pp. 1986-1999
    • Keyes, W.M.1    Wu, Y.2    Vogel, H.3    Guo, X.4    Lowe, S.W.5    Mills, A.A.6
  • 47
    • 84985376574 scopus 로고
    • Hair growth in mouse mutants affecting coat texture
    • Trigg MJ. Hair growth in mouse mutants affecting coat texture. J Zool 1972; 168: 165-198.
    • (1972) J Zool , vol.168 , pp. 165-198
    • Trigg, M.J.1
  • 51
    • 34548799705 scopus 로고    scopus 로고
    • Methods to detect biomarkers of cellular senescence: The senescence-associated β-galactosidase assay
    • DOI 10.1385/1-59745-361-7:21, Biological Aging: Methods and Protocols
    • Itahana K, Campisi J, Dimri GP. Methods to detect biomarkers of cellular senescence: the senescence-associated b-galactosidase assay. Methods Mol Biol 2007; 371: 21-31. (Pubitemid 350183415)
    • (2007) Methods in Molecular Biology , vol.371 , pp. 21-31
    • Itahana, K.1    Campisi, J.2    Dimri, G.P.3
  • 52
    • 79958710624 scopus 로고    scopus 로고
    • Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence
    • Guerra C, Collado M, Navas C, Schuhmacher AJ, Hernández-Porras I, Cañamero M et al. Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. Cancer Cell 2011; 19: 728-739.
    • (2011) Cancer Cell , vol.19 , pp. 728-739
    • Guerra, C.1    Collado, M.2    Navas, C.3    Schuhmacher, A.J.4    Hernández-Porras, I.5    Cañamero, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.