메뉴 건너뛰기




Volumn 64, Issue 17, 2004, Pages 6035-6040

Mek1 alters epidermal growth and differentiation

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE 1; RAF PROTEIN; RAS PROTEIN;

EID: 4344620189     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-0017     Document Type: Article
Times cited : (67)

References (33)
  • 3
    • 0034667593 scopus 로고    scopus 로고
    • Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
    • Kolch W. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 2000;351 (Pt 2):289-305.
    • (2000) Biochem J , vol.351 , Issue.PART 2 , pp. 289-305
    • Kolch, W.1
  • 4
    • 17744378364 scopus 로고    scopus 로고
    • MEK kinase activity is not necessary for Raf-1 function
    • Huser M, Luckett J, Chiloeches A, et al. MEK kinase activity is not necessary for Raf-1 function. EMBO J 2001;20:1940-51.
    • (2001) EMBO J , vol.20 , pp. 1940-1951
    • Huser, M.1    Luckett, J.2    Chiloeches, A.3
  • 5
    • 0034762203 scopus 로고    scopus 로고
    • The Raf/MEK/ERK pathway: New concepts of activation
    • Peyssonnaux C, Eychene A. The Raf/MEK/ERK pathway: new concepts of activation. Biol Cell 2001;93:53-62.
    • (2001) Biol Cell , vol.93 , pp. 53-62
    • Peyssonnaux, C.1    Eychene, A.2
  • 6
    • 0242361581 scopus 로고    scopus 로고
    • Transcriptional regulation by the MAP kinase signaling cascades
    • Yang SH, Sharrocks AD, Whitmarsh AJ. Transcriptional regulation by the MAP kinase signaling cascades. Gene (Amst.) 2003;320:3-21.
    • (2003) Gene (Amst.) , vol.320 , pp. 3-21
    • Yang, S.H.1    Sharrocks, A.D.2    Whitmarsh, A.J.3
  • 7
    • 0033535584 scopus 로고    scopus 로고
    • Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta
    • Giroux S, Tremblay M, Bernard D, et al. Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta. Curr Biol 1999;9:369-72.
    • (1999) Curr Biol , vol.9 , pp. 369-372
    • Giroux, S.1    Tremblay, M.2    Bernard, D.3
  • 8
    • 1242290740 scopus 로고    scopus 로고
    • Mek2 is dispensable for mouse growth and development
    • Belanger LF, Roy S, Tremblay M, et al. Mek2 is dispensable for mouse growth and development. Mol Cell Biol 2003;23:4778-87.
    • (2003) Mol Cell Biol , vol.23 , pp. 4778-4787
    • Belanger, L.F.1    Roy, S.2    Tremblay, M.3
  • 9
    • 0021042222 scopus 로고
    • Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: Contrasting effects of viruses and chemicals
    • Yuspa SH, Vass W, Scolnick E. Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: contrasting effects of viruses and chemicals. Cancer Res 1983;43:6021-30.
    • (1983) Cancer Res , vol.43 , pp. 6021-6030
    • Yuspa, S.H.1    Vass, W.2    Scolnick, E.3
  • 11
    • 0028609621 scopus 로고
    • Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha
    • Dlugosz AA, Cheng C, Williams EK, Dharia AG, Denning MF, Yuspa SH. Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha. Cancer Res 1994;54:6413-20.
    • (1994) Cancer Res , vol.54 , pp. 6413-6420
    • Dlugosz, A.A.1    Cheng, C.2    Williams, E.K.3    Dharia, A.G.4    Denning, M.F.5    Yuspa, S.H.6
  • 12
    • 0035942177 scopus 로고    scopus 로고
    • Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation
    • Lin AW, Lowe SW. Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. Proc Natl Acad Sci USA 2001;98:5025-30.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5025-5030
    • Lin, A.W.1    Lowe, S.W.2
  • 13
    • 0034731423 scopus 로고    scopus 로고
    • Ras-independent activation of the Raf/MEK/Erk pathway upon calcium-induced differentiation of keratinocytes
    • Schmidt M, Goebeler M, Posern G, et al. Ras-independent activation of the Raf/MEK/Erk pathway upon calcium-induced differentiation of keratinocytes. J Biol Chem 2000;275:41011-7.
    • (2000) J Biol Chem , vol.275 , pp. 41011-41017
    • Schmidt, M.1    Goebeler, M.2    Posern, G.3
  • 14
    • 0034745388 scopus 로고    scopus 로고
    • p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes
    • Roper E, Weinberg W, Watt FM, Land H. p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes. EMBO Rep 2001;2:145-50.
    • (2001) EMBO Rep , vol.2 , pp. 145-150
    • Roper, E.1    Weinberg, W.2    Watt, F.M.3    Land, H.4
  • 15
    • 85047698904 scopus 로고    scopus 로고
    • Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation
    • Dajee M, Tarutani M, Deng H, Cai T, Khavari PA. Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation. Oncogene 2002;21:1527-38.
    • (2002) Oncogene , vol.21 , pp. 1527-1538
    • Dajee, M.1    Tarutani, M.2    Deng, H.3    Cai, T.4    Khavari, P.A.5
  • 16
    • 0037439686 scopus 로고    scopus 로고
    • Inducible activation of ras and raf in adult epidermis
    • Tarutani M, Cai T, Dajee M, Khavari PA. Inducible activation of ras and raf in adult epidermis. Cancer Res 2003;63:319-23.
    • (2003) Cancer Res , vol.63 , pp. 319-323
    • Tarutani, M.1    Cai, T.2    Dajee, M.3    Khavari, P.A.4
  • 17
    • 0037102561 scopus 로고    scopus 로고
    • Distinct requirements for Ras oncogenesis in human versus mouse cells
    • Hamad NM, Elconin JH, Karnoub AE, et al. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev 2002;16:2045-57.
    • (2002) Genes Dev , vol.16 , pp. 2045-2057
    • Hamad, N.M.1    Elconin, J.H.2    Karnoub, A.E.3
  • 18
    • 0034883588 scopus 로고    scopus 로고
    • A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis
    • Haase I, Hobbs RM, Romero MR, Broad S, Watt FM. A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis. J Clin Investig 2001;108:527-36.
    • (2001) J Clin Investig , vol.108 , pp. 527-536
    • Haase, I.1    Hobbs, R.M.2    Romero, M.R.3    Broad, S.4    Watt, F.M.5
  • 19
    • 0029833422 scopus 로고    scopus 로고
    • Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
    • Kinsella TM, Nolan GP. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum Gene Ther 1996;7:1405-13.
    • (1996) Hum Gene Ther , vol.7 , pp. 1405-1413
    • Kinsella, T.M.1    Nolan, G.P.2
  • 20
    • 0028141496 scopus 로고
    • Transformation of mammalian cells by constitutively active MAP kinase kinase
    • Mansour SJ, Matten WT, Hermann AS, et al. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science (Wash. DC) 1994;265:966-70.
    • (1994) Science (Wash. DC) , vol.265 , pp. 966-970
    • Mansour, S.J.1    Matten, W.T.2    Hermann, A.S.3
  • 21
    • 0030033473 scopus 로고    scopus 로고
    • Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses
    • Mansour SJ, Candia JM, Gloor KK, Ahn NG. Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses. Cell Growth Differ 1996;7:243-50.
    • (1996) Cell Growth Differ , vol.7 , pp. 243-250
    • Mansour, S.J.1    Candia, J.M.2    Gloor, K.K.3    Ahn, N.G.4
  • 22
    • 0033613944 scopus 로고    scopus 로고
    • 2-M checkpoint arrest in cells exposed to ionizing radiation
    • 2-M checkpoint arrest in cells exposed to ionizing radiation. J Biol Chem 1999;274:2732-42.
    • (1999) J Biol Chem , vol.274 , pp. 2732-2742
    • Abbott, D.W.1    Holt, J.T.2
  • 23
    • 0030835430 scopus 로고    scopus 로고
    • Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1
    • Woods D, Parry D, Cherwinski H, Bosch E, Lees E, McMahon M. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol Cell Biol 1997;17:5598-611.
    • (1997) Mol Cell Biol , vol.17 , pp. 5598-5611
    • Woods, D.1    Parry, D.2    Cherwinski, H.3    Bosch, E.4    Lees, E.5    McMahon, M.6
  • 24
    • 0034719381 scopus 로고    scopus 로고
    • A conditionally active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells
    • Blalock WL, Pearce M, Steelman LS, et al. A conditionally active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells. Oncogene 2000;19:526-36.
    • (2000) Oncogene , vol.19 , pp. 526-536
    • Blalock, W.L.1    Pearce, M.2    Steelman, L.S.3
  • 25
    • 0000425845 scopus 로고
    • Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
    • Vassar R, Rosenberg M, Ross S, Tyner A, Fuchs E. Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc Natl Acad Sci USA 1989;86:1563-7.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1563-1567
    • Vassar, R.1    Rosenberg, M.2    Ross, S.3    Tyner, A.4    Fuchs, E.5
  • 26
    • 0029906097 scopus 로고    scopus 로고
    • Corrective gene transfer in the human skin disorder lamellar ichthyosis
    • Choate KA, Medalie DA, Morgan JR, Khavari PA. Corrective gene transfer in the human skin disorder lamellar ichthyosis. Nat Med 1996;2:1263-7.
    • (1996) Nat Med , vol.2 , pp. 1263-1267
    • Choate, K.A.1    Medalie, D.A.2    Morgan, J.R.3    Khavari, P.A.4
  • 27
    • 0037421484 scopus 로고    scopus 로고
    • NFkappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
    • Dajee M, Lazarov M, Zhang JY, et al. NFkappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature (Lond.) 2003;421:639-43.
    • (2003) Nature (Lond.) , vol.421 , pp. 639-643
    • Dajee, M.1    Lazarov, M.2    Zhang, J.Y.3
  • 28
    • 0030112254 scopus 로고    scopus 로고
    • Multistage epidermal carcinogenesis in transgenic mice: Cooperativity and paradox
    • Greenhalgh DA, Wang XJ, Roop DR. Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox. J Investig Dermatol Symp Proc 1996;1: 162-76.
    • (1996) J Investig Dermatol Symp Proc , vol.1 , pp. 162-176
    • Greenhalgh, D.A.1    Wang, X.J.2    Roop, D.R.3
  • 29
    • 0036239642 scopus 로고    scopus 로고
    • Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo
    • Nguyen A, Burack WR, Stock JL, et al. Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol 2002;22:3035-45.
    • (2002) Mol Cell Biol , vol.22 , pp. 3035-3045
    • Nguyen, A.1    Burack, W.R.2    Stock, J.L.3
  • 30
  • 32
    • 0035911147 scopus 로고    scopus 로고
    • A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment
    • Wunderlich W, Fialka I, Teis D, et al. A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment. J Cell Biol 2001;152:765-76.
    • (2001) J Cell Biol , vol.152 , pp. 765-776
    • Wunderlich, W.1    Fialka, I.2    Teis, D.3
  • 33
    • 0033539167 scopus 로고    scopus 로고
    • Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP
    • Yeung K, Seitz T, Li S, et al. Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP. Nature (Lond.) 1999;401:173-7.
    • (1999) Nature (Lond.) , vol.401 , pp. 173-177
    • Yeung, K.1    Seitz, T.2    Li, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.