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Volumn 185, Issue 3, 2009, Pages 409-422

Erk1/2 MAP kinases are required for epidermal G2/M progression

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; S6 KINASE; CYCLIN B; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; SMALL INTERFERING RNA;

EID: 65649099808     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200804038     Document Type: Article
Times cited : (80)

References (50)
  • 1
    • 0034885470 scopus 로고    scopus 로고
    • Expression pattern of the AP-1 family in endometrial cancer: Correlations with cell cycle regulators
    • Bamberger, A.M., K. Milde-Langosch, E. Rossing, C. Goemann, and T. Loning. 2001. Expression pattern of the AP-1 family in endometrial cancer: correlations with cell cycle regulators. J. Cancer Res. Clin. Oncol. 127:545-550.
    • (2001) J. Cancer Res. Clin. Oncol , vol.127 , pp. 545-550
    • Bamberger, A.M.1    Milde-Langosch, K.2    Rossing, E.3    Goemann, C.4    Loning, T.5
  • 2
    • 33645072441 scopus 로고    scopus 로고
    • p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis
    • Bourcier, C., A. Jacquel, J. Hess, I. Peyrottes, P. Angel, P. Hofman, P. Auberger, J. Pouyssegur, and G. Pages. 2006. p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis. Cancer Res. 66:2700-2707.
    • (2006) Cancer Res , vol.66 , pp. 2700-2707
    • Bourcier, C.1    Jacquel, A.2    Hess, J.3    Peyrottes, I.4    Angel, P.5    Hofman, P.6    Auberger, P.7    Pouyssegur, J.8    Pages, G.9
  • 3
    • 33947589440 scopus 로고    scopus 로고
    • Regulation of protein phosphorylation within the MKK1-ERK2 complex by MP1 and the MP1*P14 heterodimer
    • Brahma, A., and K.N. Dalby. 2007. Regulation of protein phosphorylation within the MKK1-ERK2 complex by MP1 and the MP1*P14 heterodimer. Arch. Biochem. Biophys. 460:85-91.
    • (2007) Arch. Biochem. Biophys , vol.460 , pp. 85-91
    • Brahma, A.1    Dalby, K.N.2
  • 5
    • 0032477854 scopus 로고    scopus 로고
    • Assembly of cyclin D- dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
    • Cheng, M., V. Sexl, C.J. Sherr, and M.F. Roussel. 1998. Assembly of cyclin D- dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc. Natl. Acad. Sci. USA. 95:1091-1096.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1091-1096
    • Cheng, M.1    Sexl, V.2    Sherr, C.J.3    Roussel, M.F.4
  • 6
    • 0033559264 scopus 로고    scopus 로고
    • The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
    • Cheng, M., P. Olivier, J.A. Diehl, M. Fero, M.F. Roussel, J.M. Roberts, and C.J. Sherr. 1999. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18:1571-1583.
    • (1999) EMBO J , vol.18 , pp. 1571-1583
    • Cheng, M.1    Olivier, P.2    Diehl, J.A.3    Fero, M.4    Roussel, M.F.5    Roberts, J.M.6    Sherr, C.J.7
  • 7
    • 0029906097 scopus 로고    scopus 로고
    • Corrective gene transfer in the human skin disorder lamellar ichthyosis
    • Choate, K.A., D.A. Medalie, J.R. Morgan, and P.A. Khavari. 1996. Corrective gene transfer in the human skin disorder lamellar ichthyosis. Nat. Med. 2:1263-1267.
    • (1996) Nat. Med , vol.2 , pp. 1263-1267
    • Choate, K.A.1    Medalie, D.A.2    Morgan, J.R.3    Khavari, P.A.4
  • 8
    • 85047698904 scopus 로고    scopus 로고
    • Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation
    • Dajee, M., M. Tarutani, H. Deng, T. Cai, and P.A. Khavari. 2002. Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation. Oncogene. 21:1527-1538.
    • (2002) Oncogene , vol.21 , pp. 1527-1538
    • Dajee, M.1    Tarutani, M.2    Deng, H.3    Cai, T.4    Khavari, P.A.5
  • 10
    • 0035824561 scopus 로고    scopus 로고
    • Constitutive activation of extracellular signal-regulated kinase 2 by syn- ergistic point mutations
    • Emrick, M.A., A.N. Hoofnagle, A.S. Miller, L.F. Ten Eyck, and N.G. Ahn. 2001. Constitutive activation of extracellular signal-regulated kinase 2 by syn- ergistic point mutations. J. Biol. Chem. 276:46469-46479.
    • (2001) J. Biol. Chem , vol.276 , pp. 46469-46479
    • Emrick, M.A.1    Hoofnagle, A.N.2    Miller, A.S.3    Ten Eyck, L.F.4    Ahn, N.G.5
  • 11
  • 12
    • 34247358156 scopus 로고    scopus 로고
    • ERK2 but not ERK1 plays a key role in hepatocyte replication: An RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes
    • Fremin, C., F. Ezan, P. Boisselier, A. Bessard, G. Pages, J. Pouyssegur, and G. Baffet. 2007. ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes. Hepatology. 45:1035-1045.
    • (2007) Hepatology , vol.45 , pp. 1035-1045
    • Fremin, C.1    Ezan, F.2    Boisselier, P.3    Bessard, A.4    Pages, G.5    Pouyssegur, J.6    Baffet, G.7
  • 13
    • 0040175067 scopus 로고    scopus 로고
    • Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction
    • Frodin, M., and S. Gammeltoft. 1999. Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction. Mol. Cell. Endocrinol. 151:65-77.
    • (1999) Mol. Cell. Endocrinol , vol.151 , pp. 65-77
    • Frodin, M.1    Gammeltoft, S.2
  • 14
    • 40949121441 scopus 로고    scopus 로고
    • Transcriptional profiling defines the roles of ERK and p38 kinases in epidermal keratino- cytes
    • Gazel, A., R.I. Nijhawan, R. Walsh, and M. Blumenberg. 2008. Transcriptional profiling defines the roles of ERK and p38 kinases in epidermal keratino- cytes. J. Cell. Physiol. 215:292-308.
    • (2008) J. Cell. Physiol , vol.215 , pp. 292-308
    • Gazel, A.1    Nijhawan, R.I.2    Walsh, R.3    Blumenberg, M.4
  • 19
    • 66649089291 scopus 로고    scopus 로고
    • 17:312-317
    • 17:312-317.
  • 20
    • 0029833422 scopus 로고    scopus 로고
    • Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
    • Kinsella, T.M., and G.P. Nolan. 1996. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum. Gene Ther. 7:1405-1413.
    • (1996) Hum. Gene Ther , vol.7 , pp. 1405-1413
    • Kinsella, T.M.1    Nolan, G.P.2
  • 21
    • 33646399160 scopus 로고    scopus 로고
    • Targeting the ERK signaling pathway in cancer therapy
    • Kohno, M., and J. Pouyssegur. 2006. Targeting the ERK signaling pathway in cancer therapy. Ann. Med. 38:200-211.
    • (2006) Ann. Med , vol.38 , pp. 200-211
    • Kohno, M.1    Pouyssegur, J.2
  • 22
    • 0029786329 scopus 로고    scopus 로고
    • Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
    • Lavoie, J.N., G. L'Allemain, A. Brunet, R. Mliller, and J. Pouyssegur. 1996. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J. Biol. Chem. 271:20608-20616.
    • (1996) J. Biol. Chem , vol.271 , pp. 20608-20616
    • Lavoie, J.N.1    L'Allemain, G.2    Brunet, A.3    Mliller, R.4    Pouyssegur, J.5
  • 24
    • 2142805256 scopus 로고    scopus 로고
    • Escaping G1 restraints on neoplasia: Cdk4 regulation by Ras and NF- KappaB
    • Lazarov, M., C.L. Green, J.Y. Zhang, Y. Kubo, M. Dajee, and P.A. Khavari. 2003. Escaping G1 restraints on neoplasia: Cdk4 regulation by Ras and NF- KappaB. Cell Cycle. 2:79-80.
    • (2003) Cell Cycle , vol.2 , pp. 79-80
    • Lazarov, M.1    Green, C.L.2    Zhang, J.Y.3    Kubo, Y.4    Dajee, M.5    Khavari, P.A.6
  • 26
    • 0033067558 scopus 로고    scopus 로고
    • interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes. Mol. Cell. Biol. 19:5113-5123.
    • interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes. Mol. Cell. Biol. 19:5113-5123.
  • 27
    • 1242272924 scopus 로고    scopus 로고
    • The MAP kinase pathway is required for entry into mitosis and cell survival
    • Liu, X., S.Yan, T. Zhou, Y. Terada, and R.L. Erikson. 2004. The MAP kinase pathway is required for entry into mitosis and cell survival. Oncogene. 23:763-776.
    • (2004) Oncogene , vol.23 , pp. 763-776
    • Liu, X.1    Yan, S.2    Zhou, T.3    Terada, Y.4    Erikson, R.L.5
  • 28
    • 34248563290 scopus 로고    scopus 로고
    • The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
    • Meloche, S., and J. Pouyssegur. 2007. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene. 26:3227-3239.
    • (2007) Oncogene , vol.26 , pp. 3227-3239
    • Meloche, S.1    Pouyssegur, J.2
  • 29
    • 0036051342 scopus 로고    scopus 로고
    • Molecular interpretation of ERK signal duration by immediate early gene products
    • Murphy, L.O., S. Smith, R.H. Chen, D.C. Fingar, and J. Blenis. 2002. Molecular interpretation of ERK signal duration by immediate early gene products. Nat. Cell Biol. 4:556-564.
    • (2002) Nat. Cell Biol , vol.4 , pp. 556-564
    • Murphy, L.O.1    Smith, S.2    Chen, R.H.3    Fingar, D.C.4    Blenis, J.5
  • 30
    • 28244497051 scopus 로고    scopus 로고
    • Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe
    • Niida, H., S. Tsuge, Y. Katsuno, A. Konishi, N. Takeda, and M. Nakanishi. 2005. Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe. J. Biol. Chem. 280:39246-39252.
    • (2005) J. Biol. Chem , vol.280 , pp. 39246-39252
    • Niida, H.1    Tsuge, S.2    Katsuno, Y.3    Konishi, A.4    Takeda, N.5    Nakanishi, M.6
  • 32
    • 34247888862 scopus 로고    scopus 로고
    • Dimerization in protein kinase signaling
    • Pelech, S. 2006. Dimerization in protein kinase signaling. J. Biol. 5:12.
    • (2006) J. Biol , vol.5 , pp. 12
    • Pelech, S.1
  • 33
    • 0041926731 scopus 로고    scopus 로고
    • Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
    • Pouyssegur, J., and P. Lenormand. 2003. Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Eur. J. Biochem. 270:3291-3299.
    • (2003) Eur. J. Biochem , vol.270 , pp. 3291-3299
    • Pouyssegur, J.1    Lenormand, P.2
  • 34
    • 0036787934 scopus 로고    scopus 로고
    • Distinct cell cycle timing requirements for extracellular signal- regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis
    • Roberts, E.C., P.S. Shapiro, T.S. Nahreini, G. Pages, J. Pouyssegur, and N.G. Ahn. 2002. Distinct cell cycle timing requirements for extracellular signal- regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis. Mol. Cell. Biol. 22:7226-7241.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 7226-7241
    • Roberts, E.C.1    Shapiro, P.S.2    Nahreini, T.S.3    Pages, G.4    Pouyssegur, J.5    Ahn, N.G.6
  • 36
    • 4344620189 scopus 로고    scopus 로고
    • Mek1 alters epidermal growth and differentiation
    • Scholl, F.A., P.A. Dumesic, and P.A. Khavari. 2004. Mek1 alters epidermal growth and differentiation. Cancer Res. 64:6035-6040.
    • (2004) Cancer Res , vol.64 , pp. 6035-6040
    • Scholl, F.A.1    Dumesic, P.A.2    Khavari, P.A.3
  • 37
  • 38
    • 34547204160 scopus 로고    scopus 로고
    • The MEK/ERK cascade: From signaling specificity to diverse functions
    • Shaul, Y.D., and R. Seger. 2007. The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim. Biophys. Acta. 1773:1213-1226.
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 1213-1226
    • Shaul, Y.D.1    Seger, R.2
  • 39
    • 33845436389 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosis
    • Shinohara, M., A.V. Mikhailov, J.A. Aguirre-Ghiso, and C.L. Rieder. 2006. Extracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosis. Mol. Biol. Cell. 17:5227-5240.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 5227-5240
    • Shinohara, M.1    Mikhailov, A.V.2    Aguirre-Ghiso, J.A.3    Rieder, C.L.4
  • 40
    • 10044281770 scopus 로고    scopus 로고
    • Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells
    • Silverman, E., M. Frodin, S. Gammeltoft, and J.L. Maller. 2004. Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells. Mol. Cell. Biol. 24:10573-10583.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 10573-10583
    • Silverman, E.1    Frodin, M.2    Gammeltoft, S.3    Maller, J.L.4
  • 41
    • 0037439686 scopus 로고    scopus 로고
    • Inducible activation of Ras and Raf in adult epidermis
    • Tarutani, M., T. Cai, M. Dajee, and P.A. Khavari. 2003. Inducible activation of Ras and Raf in adult epidermis. Cancer Res. 63:319-323.
    • (2003) Cancer Res , vol.63 , pp. 319-323
    • Tarutani, M.1    Cai, T.2    Dajee, M.3    Khavari, P.A.4
  • 42
    • 33751230475 scopus 로고    scopus 로고
    • p63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • Truong, A.B., M. Kretz, T.W. Ridky, R. Kimmel, and P.A. Khavari. 2006. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev. 20:3185-3197.
    • (2006) Genes Dev , vol.20 , pp. 3185-3197
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3    Kimmel, R.4    Khavari, P.A.5
  • 43
    • 33845904217 scopus 로고    scopus 로고
    • ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially
    • Vantaggiato, C., I. Formentini, A. Bondanza, C. Bonini, L. Naldini, and R. Brambilla. 2006. ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. J. Biol. 5:14.
    • (2006) J. Biol , vol.5 , pp. 14
    • Vantaggiato, C.1    Formentini, I.2    Bondanza, A.3    Bonini, C.4    Naldini, L.5    Brambilla, R.6
  • 44
    • 34247253325 scopus 로고    scopus 로고
    • ERK activity and G1 phase progression: Identifying dispensable versus essential activities and primary versus secondary targets
    • Villanueva, J., Y. Yung, J.L. Walker, and R.K. Assoian. 2007. ERK activity and G1 phase progression: identifying dispensable versus essential activities and primary versus secondary targets. Mol. Biol. Cell. 18:1457-1463.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1457-1463
    • Villanueva, J.1    Yung, Y.2    Walker, J.L.3    Assoian, R.K.4
  • 46
    • 0033613250 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibro- blasts
    • Wright, J.H., E. Munar, D.R. Jameson, P.R. Andreassen, R.L. Margolis, R. Seger, and E.G. Krebs. 1999. Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibro- blasts. Proc. Natl. Acad. Sci. USA. 96:11335-11340.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11335-11340
    • Wright, J.H.1    Munar, E.2    Jameson, D.R.3    Andreassen, P.R.4    Margolis, R.L.5    Seger, R.6    Krebs, E.G.7
  • 47
    • 33744974769 scopus 로고    scopus 로고
    • Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression
    • Yamamoto, T., M. Ebisuya, F. Ashida, K. Okamoto, S.Yonehara, and E. Nishida. 2006. Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression. Curr. Biol. 16:1171-1182.
    • (2006) Curr. Biol , vol.16 , pp. 1171-1182
    • Yamamoto, T.1    Ebisuya, M.2    Ashida, F.3    Okamoto, K.4    Yonehara, S.5    Nishida, E.6
  • 49
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
    • Yoon, S., and R. Seger. 2006. The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors. 24:21-44.
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1    Seger, R.2
  • 50
    • 27744564224 scopus 로고    scopus 로고
    • RNA interference (RNAi) for extracellular signal-regulated kinase 1 (ERK1) alone is sufficient to suppress cell viability in ovarian cancer cells
    • Zeng, P., H.A. Wagoner, O.H. Pescovitz, and R. Steinmetz. 2005. RNA interference (RNAi) for extracellular signal-regulated kinase 1 (ERK1) alone is sufficient to suppress cell viability in ovarian cancer cells. Cancer Biol. Ther. 4:961-967.
    • (2005) Cancer Biol. Ther , vol.4 , pp. 961-967
    • Zeng, P.1    Wagoner, H.A.2    Pescovitz, O.H.3    Steinmetz, R.4


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