Quaternized starch-based carrier for siRNA delivery: From cellular uptake to gene silencing

Journal of Controlled Release

Volumn 185, Issue 1, 2014, Pages 109-120

  Amar Lewis, Eliz ^a   Azagury, Aharon ^a   Chintakunta, Ramesh ^a   Goldbart, Riki ^a   Traitel, Tamar ^a   Prestwood, Jackson ^b   Landesman Milo, Dalit ^c   Peer, Dan ^c   Kost, Joseph ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Drug delivery; Polysaccharide; Quaternized starch; Self assembly complexes; Small interfering RNA

Indexed keywords

CELL CULTURE; DRUG DELIVERY; GENES; GENETIC ENGINEERING; MOLECULAR BIOLOGY; POLYSACCHARIDES; RNA; SELF ASSEMBLY;

ADENOCARCINOMA CELLS; ENZYMATIC DEGRADATION; MODIFIED POTATO STARCH; NATURAL POLYSACCHARIDE; PHYSICAL CHARACTERISTICS; POSITIVE SURFACE CHARGE; SMALL INTERFERING RNA; STARCH DERIVATIVES;

STARCH;

MULTIDRUG RESISTANCE PROTEIN; NANOPARTICLE; POTATO STARCH; SMALL INTERFERING RNA; DRUG CARRIER; STARCH;

AGAR GEL ELECTROPHORESIS; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOCOMPATIBILITY; BIODEGRADABILITY; CANCER CELL LINE; CELL KINETICS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYMATIC DEGRADATION; GENE DELIVERY SYSTEM; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; LIGHT SCATTERING; OVARY ADENOCARCINOMA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RNA INTERFERENCE; STATIC ELECTRICITY; SURFACE CHARGE; CHEMICAL STRUCTURE; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; TUMOR CELL LINE;

CELL LINE, TUMOR; DRUG CARRIERS; HUMANS; MODELS, MOLECULAR; NANOPARTICLES; P-GLYCOPROTEIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; STARCH; TRANSFECTION;

EID: 84901817333     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.04.031     Document Type: Article

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