Co-delivery of small interfering RNA and plasmid DNA using a polymeric vector incorporating endosomolytic oligomeric sulfonamide

Biomaterials

Volumn 32, Issue 21, 2011, Pages 4914-4924

  Chang Kang, Han ^a   Bae, You Han ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b Utah Inha DDS and Advanced Theapeutics Research Center   (South Korea)

Author keywords

Co delivery; Oligomeric sulfonamide; PDNA delivery; Polymer gene delivery; SiRNA delivery

Indexed keywords

CATIONIC POLYMERS; CO-DELIVERY; GENE SILENCING; NANO-SIZED; OLIGOMERIC SULFONAMIDE; PDNA DELIVERY; PLASMID DNA; PLASMID DNA (PDNA); POLY-L-LYSINE; POLYANIONS; POLYCATIONS; POLYPLEXES; SIRNA DELIVERY; SMALL INTERFERING RNA; SMALL INTERFERING RNA (SIRNA); THERAPEUTIC EFFECTS;

AMIDES; AMINO ACIDS; BIOMOLECULES; DNA; GENE THERAPY; GENE TRANSFER; OLIGOMERS; RNA; SULFUR COMPOUNDS;

POLYMERS;

GREEN FLUORESCENT PROTEIN; NANOPARTICLE; OLIGOMER; PLASMID DNA; POLYLYSINE; POLYMER; SMALL INTERFERING RNA; SULFADIAZINE; SULFONAMIDE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENDOSOME; FEASIBILITY STUDY; GENE SILENCING; HUMAN; HUMAN CELL; PARTICLE SIZE; PKA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE;

BIOCOMPATIBLE MATERIALS; DNA; DRUG CARRIERS; GENE SILENCING; GENETIC VECTORS; HEK293 CELLS; HUMANS; LUMINESCENT PROTEINS; MATERIALS TESTING; PLASMIDS; POLYAMINES; POLYMERS; RNA, SMALL INTERFERING; SULFONAMIDES;

EID: 79955772881     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.03.042     Document Type: Article

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