Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss

Journal of Neuroscience

Volumn 34, Issue 23, 2014, Pages 7836-7844

  Lee, Youngsoo ^a,b   Brown, Eric J ^c   Chang, Sandy ^d   McKinnon, Peter J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b Ajou University School of Medicine   (South Korea)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ATM; Cerebellum; DNA damage; Neural development; Telomeres

Indexed keywords

ATM PROTEIN; BRCA2 PROTEIN; POT1A PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM FUNCTION; CEREBELLUM; CHROMOSOME DAMAGE; CONTROLLED STUDY; CYTOGENETICS; DEGENERATIVE DISEASE; DNA DAMAGE; ENZYME ACTIVITY; GENOMIC INSTABILITY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TELOMERE DYSFUNCTION; WESTERN BLOTTING;

ATM; CEREBELLUM; DNA DAMAGE; NEURAL DEVELOPMENT; TELOMERES;

ANIMALS; ANIMALS, NEWBORN; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BETA-GALACTOSIDASE; BRAIN; CELL CYCLE; CELL CYCLE PROTEINS; CELLS, CULTURED; DNA DAMAGE; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION; MALE; MICE; MICE, TRANSGENIC; NESTIN; NEURONS; TELOMERE;

EID: 84901792729     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4245-13.2014     Document Type: Article

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