Lactoferrin-modified poly(ethylene glycol)-grafted BSA nanoparticles as a dual-targeting carrier for treating brain gliomas

Molecular Pharmaceutics

Volumn 11, Issue 6, 2014, Pages 1823-1834

  Su, Zhigui ^a   Xing, Lei ^a   Chen, Yinan ^a   Xu, Yurui ^a   Yang, Feifei ^a   Zhang, Can ^a   Ping, Qineng ^a   Xiao, Yanyu ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

bovine serum albumin nanoparticles; dual targeting; electrostatic interaction; gliomas; lactoferrin; mPEG2000

Indexed keywords

BOVINE SERUM ALBUMIN; DOXORUBICIN; LACTOFERRIN; MACROGOL 2000; NANOCARRIER; NANOPARTICLE; ANTINEOPLASTIC ANTIBIOTIC; DRUG CARRIER; MACROGOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BODY DISTRIBUTION; BRAIN CAPILLARY ENDOTHELIAL CELL; CIRCULATION TIME; CLINICAL EFFECTIVENESS; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; DESOLVATION TECHNIQUE; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG RETENTION; DRUG TARGETING; DRUG UPTAKE; ENDOCYTOSIS; GLIOMA; GLIOMA CELL; HYDROPHILICITY; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; LIPOPHILICITY; NONHUMAN; PARTICLE SIZE; PH; PHAGOCYTOSIS; PHARMACOKINETICS; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SOLUTION AND SOLUBILITY; TISSUE DISTRIBUTION; ZETA POTENTIAL; ANIMAL; BRAIN NEOPLASMS; ENDOTHELIUM CELL; MEDICINAL CHEMISTRY; METABOLISM; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CHEMISTRY, PHARMACEUTICAL; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; GLIOMA; LACTOFERRIN; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN, BOVINE; TISSUE DISTRIBUTION;

EID: 84901779269     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500238m     Document Type: Article

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