Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine

Molecular Pharmaceutics

Volumn 8, Issue 5, 2011, Pages 1641-1651

  Su, Zhigui ^a   Niu, Jiangxiu ^a   Xiao, Yanyu ^a   Ping, Qineng ^a   Sun, Minjie ^a   Huang, Aiwen ^a   You, Weiliang ^a   Sang, Xiaoye ^a   Yuan, Dongfen ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

nanostructured lipid carrier; octreotide; polyethylene glycol(100) monostearate; somatostatin receptor

Indexed keywords

CAMPTOTHECIN; HYDROXYCAMPTOTHECINE; LIPID; MACROGOL; NANOCARRIER; NANOMATERIAL; OCTREOTIDE; POLYETHYLENE; SOMATOSTATIN RECEPTOR; STEARIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; ATOMIC FORCE MICROSCOPY; CONCENTRATION (PARAMETERS); FIXED AQUEOUS LAYER THICKNESS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SYNTHESIS; THICKNESS; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CAMPTOTHECIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; HALF-LIFE; HUMANS; LIGANDS; LIPIDS; LIVER NEOPLASMS; MALE; NANOSTRUCTURES; NEOPLASM PROTEINS; OCTREOTIDE; PHYSICOCHEMICAL PHENOMENA; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SOMATOSTATIN;

EID: 80053550394     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp100463n     Document Type: Article

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