Lactoferrin is synthesized by activated microglia in the human substantia nigra and its synthesis by the human microglial CHME cell line is upregulated by tumor necrosis factor α or 1-methyl-4-phenylpyridinium treatment

Molecular Brain Research

Volumn 96, Issue 1-2, 2001, Pages 103-113

  Fillebeen, Carine ^a   Ruchoux, Marie Magdeleine ^b   Mitchell, Valérie ^c   Vincent, Sylvie ^b   Benassa, Monique ^a   Pierce, Annick ^a  

^a UNIV LILLE   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c INSERM   (France)

Author keywords

Alzheimer's disease; Inflammation; Lactoferrin; Microglia; Oxidative stress; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CD68 ANTIGEN; LACTOFERRIN; MESSENGER RNA; PROTEIN; PROTEIN CR1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CELL LINE; CELL POPULATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYOLOGY; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; IN SITU HYBRIDIZATION; INFLAMMATION; MACROPHAGE; MALE; MICROGLIA; NEUROPATHOLOGY; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYLPYRIDINIUM; AGED; ANTINEOPLASTIC AGENTS; CELL LINE, TRANSFORMED; ENCEPHALITIS; FEMALE; GENE EXPRESSION; HUMANS; LACTOFERRIN; MALE; MICROGLIA; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBSTANTIA NIGRA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035976727     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(01)00216-9     Document Type: Article

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