Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells

Journal of Controlled Release

Volumn 118, Issue 1, 2007, Pages 7-17

  Hu, Yong ^a,c   Xie, Jingwei ^b   Tong, Yen Wah ^b   Wang, Chi Hwa ^b,c  

^a NANJING UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c SINGAPORE MIT ALLIANCE   (Singapore)

Author keywords

Block copolymer; HepG2 cell; Nanoparticles; Paclitaxel; PEG conformation

Indexed keywords

FEEDING RATIO; HEPG2 CELL; PACLITAXEL; PEG CONFORMATION;

BLOCK COPOLYMERS; CONFORMATIONS; HYDROPHOBICITY; LIGHT SCATTERING; NANOSTRUCTURED MATERIALS; PARTICLE SIZE ANALYSIS; SCANNING ELECTRON MICROSCOPY;

POLYETHYLENE GLYCOLS;

COPOLYMER; MACROGOL; METHOXYPOLY(ETHYLENE GLYCOL) POLYCAPROLACTONE COPOLYMER; NANOPARTICLE; NANOSHELL; PACLITAXEL; POLYCAPROLACTONE POLY(ETHYLENE GLYCOL) POLYCAPROLACTONE COPOLYMER; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CELL STRAIN HEPG2; CONFORMATION; CYTOTOXICITY; DRUG FORMULATION; DRUG SYNTHESIS; DRUG UPTAKE; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; LIGHT SCATTERING; NANOENCAPSULATION; NANOPHARMACEUTICS; PARTICLE SIZE; PRIORITY JOURNAL; SURFACE PROPERTY; SUSTAINED RELEASE FORMULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DRUG CARRIERS; EPITHELIAL CELLS; HUMANS; LASERS; LIGHT; LIVER NEOPLASMS; MOLECULAR CONFORMATION; NANOPARTICLES; NANOTUBES; PACLITAXEL; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; SCATTERING, RADIATION; WATER;

EID: 33847095924     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.11.028     Document Type: Article

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