Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner

Cell Cycle

Volumn 13, Issue 11, 2014, Pages 1708-1716

  Lin, Yiwei ^a   Kang, Tiebang ^b   Zhou, Binhua P ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

LSD1; PARP1; Poly(ADP ribosyl)ation; PTEN; Snail

Indexed keywords

DOXORUBICIN; HISTONE H3; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OLAPARIB; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN; PROTEIN KINASE B; PROTEIN LSD1; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; HISTONE DEMETHYLASE; KDM1A PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, HUMAN; PHTHALAZINE DERIVATIVE; PIPERAZINE DERIVATIVE; PTEN PROTEIN, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE REPRESSION; HUMAN; HUMAN CELL; METHYLATION; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; TUMOR CELL; UPREGULATION; ANTAGONISTS AND INHIBITORS; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; DOXORUBICIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION; HEK293 CELLS; HISTONE DEMETHYLASES; HUMANS; PHTHALAZINES; PIPERAZINES; POLY(ADP-RIBOSE) POLYMERASES; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; TETRAZOLIUM SALTS; THIAZOLES; TRANSCRIPTION FACTORS;

EID: 84901776328     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.28619     Document Type: Article

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