-
1
-
-
84869745002
-
Redundant phenazine operons in Pseudomonas aeruginosa exhibit environment-dependent expression and differential roles in pathogenicity
-
Recinos DA, Sekedat MD, Hernandez A, Cohen TS, Sakhtah H, et al. (2012) Redundant phenazine operons in Pseudomonas aeruginosa exhibit environment-dependent expression and differential roles in pathogenicity. Proc Natl Acad Sci U S A 109: 19420-19425.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 19420-19425
-
-
Recinos, D.A.1
Sekedat, M.D.2
Hernandez, A.3
Cohen, T.S.4
Sakhtah, H.5
-
2
-
-
84871714811
-
Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence
-
Bohme K, Steinmann R, Kortmann J, Seekircher S, Heroven AK, et al. (2012) Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence. PLoS Pathog 8: e1002518.
-
(2012)
PLoS Pathog
, vol.8
-
-
Bohme, K.1
Steinmann, R.2
Kortmann, J.3
Seekircher, S.4
Heroven, A.K.5
-
3
-
-
80051915419
-
RNA-Seq-based monitoring of infection-linked changes in Vibrio cholerae gene expression
-
Mandlik A, Livny J, Robins WP, Ritchie JM, Mekalanos JJ, et al. (2011) RNA-Seq-based monitoring of infection-linked changes in Vibrio cholerae gene expression. Cell Host Microbe 10: 165-174.
-
(2011)
Cell Host Microbe
, vol.10
, pp. 165-174
-
-
Mandlik, A.1
Livny, J.2
Robins, W.P.3
Ritchie, J.M.4
Mekalanos, J.J.5
-
4
-
-
84871787592
-
A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence
-
Balasubramanian D, Schneper L, Kumari H, Mathee K, (2013) A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence. Nucleic Acids Res 41: 1-20.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 1-20
-
-
Balasubramanian, D.1
Schneper, L.2
Kumari, H.3
Mathee, K.4
-
5
-
-
84879517912
-
A novel two-component signaling system facilitates uropathogenic Escherichia coli's ability to exploit abundant host metabolites
-
Cai W, Wannemuehler Y, Dell'anna G, Nicholson B, Barbieri NL, et al. (2013) A novel two-component signaling system facilitates uropathogenic Escherichia coli's ability to exploit abundant host metabolites. PLoS Pathog 9: e1003428.
-
(2013)
PLoS Pathog
, vol.9
-
-
Cai, W.1
Wannemuehler, Y.2
Dell'anna, G.3
Nicholson, B.4
Barbieri, N.L.5
-
6
-
-
0034700175
-
Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC
-
Lyon GJ, Mayville P, Muir TW, Novick RP, (2000) Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC. Proc Natl Acad Sci U S A 97: 13330-13335.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13330-13335
-
-
Lyon, G.J.1
Mayville, P.2
Muir, T.W.3
Novick, R.P.4
-
7
-
-
0035940419
-
Mycobacterium tuberculosis signal transduction system required for persistent infections
-
Zahrt TC, Deretic V, (2001) Mycobacterium tuberculosis signal transduction system required for persistent infections. Proc Natl Acad Sci U S A 98: 12706-12711.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12706-12711
-
-
Zahrt, T.C.1
Deretic, V.2
-
8
-
-
70349541000
-
Biological insights from structures of two-component proteins
-
Gao R, Stock AM, (2009) Biological insights from structures of two-component proteins. Annu Rev Microbiol 63: 133-154.
-
(2009)
Annu Rev Microbiol
, vol.63
, pp. 133-154
-
-
Gao, R.1
Stock, A.M.2
-
10
-
-
80052050406
-
Protein phosphorylation in bacterial signal transduction
-
Kobir A, Shi L, Boskovic A, Grangeasse C, Franjevic D, et al. (2011) Protein phosphorylation in bacterial signal transduction. Biochim Biophys Acta 1810: 989-994.
-
(2011)
Biochim Biophys Acta
, vol.1810
, pp. 989-994
-
-
Kobir, A.1
Shi, L.2
Boskovic, A.3
Grangeasse, C.4
Franjevic, D.5
-
11
-
-
50149111428
-
Targeting QseC signaling and virulence for antibiotic development
-
Rasko DA, Moreira CG, Li de R, Reading NC, Ritchie JM, et al. (2008) Targeting QseC signaling and virulence for antibiotic development. Science 321: 1078-1080.
-
(2008)
Science
, vol.321
, pp. 1078-1080
-
-
Rasko, D.A.1
Moreira, C.G.2
de Li, R.3
Reading, N.C.4
Ritchie, J.M.5
-
12
-
-
77950289096
-
Novel antibacterial compounds specifically targeting the essential WalR response regulator
-
Gotoh Y, Doi A, Furuta E, Dubrac S, Ishizaki Y, et al. (2010) Novel antibacterial compounds specifically targeting the essential WalR response regulator. J Antibiot (Tokyo) 63: 127-134.
-
(2010)
J Antibiot (Tokyo)
, vol.63
, pp. 127-134
-
-
Gotoh, Y.1
Doi, A.2
Furuta, E.3
Dubrac, S.4
Ishizaki, Y.5
-
13
-
-
77949916499
-
Two-component signal transduction as potential drug targets in pathogenic bacteria
-
Gotoh Y, Eguchi Y, Watanabe T, Okamoto S, Doi A, et al. (2010) Two-component signal transduction as potential drug targets in pathogenic bacteria. Curr Opin Microbiol 13: 232-239.
-
(2010)
Curr Opin Microbiol
, vol.13
, pp. 232-239
-
-
Gotoh, Y.1
Eguchi, Y.2
Watanabe, T.3
Okamoto, S.4
Doi, A.5
-
14
-
-
84860474739
-
Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator
-
Tang YT, Gao R, Havranek JJ, Groisman EA, Stock AM, et al. (2012) Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator. Chem Biol Drug Des 79: 1007-1017.
-
(2012)
Chem Biol Drug Des
, vol.79
, pp. 1007-1017
-
-
Tang, Y.T.1
Gao, R.2
Havranek, J.J.3
Groisman, E.A.4
Stock, A.M.5
-
15
-
-
0031669931
-
Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus
-
Levin JC, Wessels MR, (1998) Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus. Mol Microbiol 30: 209-219.
-
(1998)
Mol Microbiol
, vol.30
, pp. 209-219
-
-
Levin, J.C.1
Wessels, M.R.2
-
16
-
-
33947287983
-
The two faces of Janus: virulence gene regulation by CovR/S in group A streptococci
-
Churchward G, (2007) The two faces of Janus: virulence gene regulation by CovR/S in group A streptococci. Mol Microbiol 64: 34-41.
-
(2007)
Mol Microbiol
, vol.64
, pp. 34-41
-
-
Churchward, G.1
-
17
-
-
0033053646
-
A response regulator that represses transcription of several virulence operons in the group A Streptococcus
-
Federle MJ, McIver KS, Scott JR, (1999) A response regulator that represses transcription of several virulence operons in the group A Streptococcus. J Bacteriol 181: 3649-3657.
-
(1999)
J Bacteriol
, vol.181
, pp. 3649-3657
-
-
Federle, M.J.1
McIver, K.S.2
Scott, J.R.3
-
18
-
-
27144468026
-
The global burden of group A streptococcal diseases
-
Carapetis JR, Steer AC, Mulholland EK, Weber M, (2005) The global burden of group A streptococcal diseases. Lancet Infect Dis 5: 685-694.
-
(2005)
Lancet Infect Dis
, vol.5
, pp. 685-694
-
-
Carapetis, J.R.1
Steer, A.C.2
Mulholland, E.K.3
Weber, M.4
-
19
-
-
0035313287
-
Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection
-
Engleberg NC, Heath A, Miller A, Rivera C, DiRita VJ, (2001) Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection. J Infect Dis 183: 1043-1054.
-
(2001)
J Infect Dis
, vol.183
, pp. 1043-1054
-
-
Engleberg, N.C.1
Heath, A.2
Miller, A.3
Rivera, C.4
DiRita, V.J.5
-
20
-
-
0037108912
-
Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling
-
Graham MR, Smoot LM, Migliaccio CA, Virtaneva K, Sturdevant DE, et al. (2002) Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc Natl Acad Sci USA 99: 13855-13860.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13855-13860
-
-
Graham, M.R.1
Smoot, L.M.2
Migliaccio, C.A.3
Virtaneva, K.4
Sturdevant, D.E.5
-
21
-
-
2942511333
-
CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes
-
Dalton TL, Scott JR, (2004) CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes. J Bacteriol 186: 3928-3937.
-
(2004)
J Bacteriol
, vol.186
, pp. 3928-3937
-
-
Dalton, T.L.1
Scott, J.R.2
-
22
-
-
33745471491
-
Phosphorylation of the group A streptococcal CovR response regulator causes dimerization and promoter-specific recruitment by RNA polymerase
-
Gusa AA, Gao J, Stringer V, Churchward G, Scott JR, (2006) Phosphorylation of the group A streptococcal CovR response regulator causes dimerization and promoter-specific recruitment by RNA polymerase. J Bacteriol 188: 4620-4626.
-
(2006)
J Bacteriol
, vol.188
, pp. 4620-4626
-
-
Gusa, A.A.1
Gao, J.2
Stringer, V.3
Churchward, G.4
Scott, J.R.5
-
23
-
-
84877574926
-
Comprehensive analysis of OmpR phosphorylation, dimerization, and DNA binding supports a canonical model for activation
-
Barbieri CM, Wu T, Stock AM, (2013) Comprehensive analysis of OmpR phosphorylation, dimerization, and DNA binding supports a canonical model for activation. J Mol Biol 425: 1612-1626.
-
(2013)
J Mol Biol
, vol.425
, pp. 1612-1626
-
-
Barbieri, C.M.1
Wu, T.2
Stock, A.M.3
-
24
-
-
33646233984
-
Analysis of the role of CovR and CovS in the dissemination of Streptococcus pyogenes in invasive skin disease
-
Dalton TL, Hobb RI, Scott JR, (2006) Analysis of the role of CovR and CovS in the dissemination of Streptococcus pyogenes in invasive skin disease. Microb Pathog 40: 221-227.
-
(2006)
Microb Pathog
, vol.40
, pp. 221-227
-
-
Dalton, T.L.1
Hobb, R.I.2
Scott, J.R.3
-
25
-
-
67651230633
-
CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes
-
Trevino J, Perez N, Ramirez-Pena E, Liu Z, Shelburne SA 3rd, et al. (2009) CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes. Infect Immun 77: 3141-3149.
-
(2009)
Infect Immun
, vol.77
, pp. 3141-3149
-
-
Trevino, J.1
Perez, N.2
Ramirez-Pena, E.3
Liu, Z.4
Shelburne 3rd, S.A.5
-
26
-
-
82355164180
-
Role of serine/threonine phosphatase (SP-STP) in Streptococcus pyogenes physiology and virulence
-
Agarwal S, Pancholi P, Pancholi V, (2011) Role of serine/threonine phosphatase (SP-STP) in Streptococcus pyogenes physiology and virulence. J Biol Chem 286: 41368-41380.
-
(2011)
J Biol Chem
, vol.286
, pp. 41368-41380
-
-
Agarwal, S.1
Pancholi, P.2
Pancholi, V.3
-
27
-
-
0037853258
-
A eukaryotic type serine/threonine kinase and phosphatase in Streptococcus agalactiae reversibly phosphorylate an inorganic pyrophosphatase and affect growth, cell segregation, and virulence
-
Rajagopal L, Clancy A, Rubens CE, (2003) A eukaryotic type serine/threonine kinase and phosphatase in Streptococcus agalactiae reversibly phosphorylate an inorganic pyrophosphatase and affect growth, cell segregation, and virulence. J Biol Chem 278: 14429-14441.
-
(2003)
J Biol Chem
, vol.278
, pp. 14429-14441
-
-
Rajagopal, L.1
Clancy, A.2
Rubens, C.E.3
-
28
-
-
33750492300
-
Regulation of cytotoxin expression by converging eukaryotic-type and two-component signalling mechanisms in Streptococcus agalactiae
-
Rajagopal L, Vo A, Silvestroni A, Rubens CE, (2006) Regulation of cytotoxin expression by converging eukaryotic-type and two-component signalling mechanisms in Streptococcus agalactiae. Mol Microbiol 62: 941-957.
-
(2006)
Mol Microbiol
, vol.62
, pp. 941-957
-
-
Rajagopal, L.1
Vo, A.2
Silvestroni, A.3
Rubens, C.E.4
-
29
-
-
62449179440
-
Threonine phosphorylation prevents promoter DNA binding of the Group B Streptococcus response regulator CovR
-
Lin WJ, Walthers D, Connelly JE, Burnside K, Jewell KA, et al. (2009) Threonine phosphorylation prevents promoter DNA binding of the Group B Streptococcus response regulator CovR. Mol Microbiol 71: 1477-1495.
-
(2009)
Mol Microbiol
, vol.71
, pp. 1477-1495
-
-
Lin, W.J.1
Walthers, D.2
Connelly, J.E.3
Burnside, K.4
Jewell, K.A.5
-
30
-
-
77954372403
-
Regulation of CovR expression in Group B Streptococcus impacts blood-brain barrier penetration
-
Lembo A, Gurney MA, Burnside K, Banerjee A, de los Reyes M, et al. (2010) Regulation of CovR expression in Group B Streptococcus impacts blood-brain barrier penetration. Mol Microbiol 77: 431-443.
-
(2010)
Mol Microbiol
, vol.77
, pp. 431-443
-
-
Lembo, A.1
Gurney, M.A.2
Burnside, K.3
Banerjee, A.4
de los Reyes, M.5
-
31
-
-
84880689891
-
A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta
-
Whidbey C, Harrell MI, Burnside K, Ngo L, Becraft AK, et al. (2013) A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta. J Exp Med 210: 1265-1281.
-
(2013)
J Exp Med
, vol.210
, pp. 1265-1281
-
-
Whidbey, C.1
Harrell, M.I.2
Burnside, K.3
Ngo, L.4
Becraft, A.K.5
-
32
-
-
0034995382
-
Repression of virulence genes by phosphorylation-dependent oligomerization of CsrR at target promoters in Streptococcus pyogenes
-
Miller AA, Engleberg NC, DiRita VJ, (2001) Repression of virulence genes by phosphorylation-dependent oligomerization of CsrR at target promoters in Streptococcus pyogenes. Mol Microbiol 40: 976-990.
-
(2001)
Mol Microbiol
, vol.40
, pp. 976-990
-
-
Miller, A.A.1
Engleberg, N.C.2
DiRita, V.J.3
-
33
-
-
0036229494
-
Identification of binding sites for the group A streptococcal global regulator CovR
-
Federle MJ, Scott JR, (2002) Identification of binding sites for the group A streptococcal global regulator CovR. Mol Microbiol 43: 1161-1172.
-
(2002)
Mol Microbiol
, vol.43
, pp. 1161-1172
-
-
Federle, M.J.1
Scott, J.R.2
-
34
-
-
40449108599
-
Variation in the group B Streptococcus CsrRS regulon and effects on pathogenicity
-
Jiang SM, Ishmael N, Hotopp JD, Puliti M, Tissi L, et al. (2008) Variation in the group B Streptococcus CsrRS regulon and effects on pathogenicity. J Bacteriol 190: 1956-1965.
-
(2008)
J Bacteriol
, vol.190
, pp. 1956-1965
-
-
Jiang, S.M.1
Ishmael, N.2
Hotopp, J.D.3
Puliti, M.4
Tissi, L.5
-
35
-
-
41549148228
-
Universally applicable methods for monitoring response regulator aspartate phosphorylation both in vitro and in vivo using Phos-tag-based reagents
-
Barbieri CM, Stock AM, (2008) Universally applicable methods for monitoring response regulator aspartate phosphorylation both in vitro and in vivo using Phos-tag-based reagents. Anal Biochem 376: 73-82.
-
(2008)
Anal Biochem
, vol.376
, pp. 73-82
-
-
Barbieri, C.M.1
Stock, A.M.2
-
36
-
-
84868112483
-
Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross-talk in Streptococcus pneumoniae D39 cells
-
Wayne KJ, Li S, Kazmierczak KM, Tsui HC, Winkler ME, (2012) Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross-talk in Streptococcus pneumoniae D39 cells. Mol Microbiol 86: 645-660.
-
(2012)
Mol Microbiol
, vol.86
, pp. 645-660
-
-
Wayne, K.J.1
Li, S.2
Kazmierczak, K.M.3
Tsui, H.C.4
Winkler, M.E.5
-
37
-
-
84875589690
-
In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgA
-
Boulanger A, Chen Q, Hinton DM, Stibitz S, (2013) In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgA. Mol Microbiol 88: 156-172.
-
(2013)
Mol Microbiol
, vol.88
, pp. 156-172
-
-
Boulanger, A.1
Chen, Q.2
Hinton, D.M.3
Stibitz, S.4
-
38
-
-
78650790948
-
Improved Phos-tag SDS-PAGE under neutral pH conditions for advanced protein phosphorylation profiling
-
Kinoshita E, Kinoshita-Kikuta E, (2011) Improved Phos-tag SDS-PAGE under neutral pH conditions for advanced protein phosphorylation profiling. Proteomics 11: 319-323.
-
(2011)
Proteomics
, vol.11
, pp. 319-323
-
-
Kinoshita, E.1
Kinoshita-Kikuta, E.2
-
39
-
-
77950429504
-
A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection
-
Shelburne SA, Olsen RJ, Suber B, Sahasrabhojane P, Sumby P, et al. (2010) A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection. PLoS Pathog 6: e1000817.
-
(2010)
PLoS Pathog
, vol.6
-
-
Shelburne, S.A.1
Olsen, R.J.2
Suber, B.3
Sahasrabhojane, P.4
Sumby, P.5
-
40
-
-
77749254854
-
Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics
-
Beres SB, Carroll RK, Shea PR, Sitkiewicz I, Martinez-Gutierrez JC, et al. (2010) Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics. Proc Natl Acad Sci U S A 107: 4371-4376.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4371-4376
-
-
Beres, S.B.1
Carroll, R.K.2
Shea, P.R.3
Sitkiewicz, I.4
Martinez-Gutierrez, J.C.5
-
41
-
-
34447573810
-
Mg(2+) signalling defines the group A streptococcal CsrRS (CovRS) regulon
-
Gryllos I, Grifantini R, Colaprico A, Jiang S, Deforce E, et al. (2007) Mg(2+) signalling defines the group A streptococcal CsrRS (CovRS) regulon. Mol Microbiol 65: 671-683.
-
(2007)
Mol Microbiol
, vol.65
, pp. 671-683
-
-
Gryllos, I.1
Grifantini, R.2
Colaprico, A.3
Jiang, S.4
Deforce, E.5
-
42
-
-
33645054791
-
Identification and biochemical characterization of a eukaryotic-type serine/threonine kinase and its cognate phosphatase in Streptococcus pyogenes: their biological functions and substrate identification
-
Jin H, Pancholi V, (2006) Identification and biochemical characterization of a eukaryotic-type serine/threonine kinase and its cognate phosphatase in Streptococcus pyogenes: their biological functions and substrate identification. J Mol Biol 357: 1351-1372.
-
(2006)
J Mol Biol
, vol.357
, pp. 1351-1372
-
-
Jin, H.1
Pancholi, V.2
-
43
-
-
80055064690
-
Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis
-
Horstmann N, Sahasrabhojane P, Suber B, Kumaraswami M, Olsen RJ, et al. (2011) Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis. PLoS Pathog 7: e1002311.
-
(2011)
PLoS Pathog
, vol.7
-
-
Horstmann, N.1
Sahasrabhojane, P.2
Suber, B.3
Kumaraswami, M.4
Olsen, R.J.5
-
44
-
-
77749271269
-
Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria
-
Kansal RG, Datta V, Aziz RK, Abdeltawab NF, Rowe S, et al. (2010) Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria. J Infect Dis 201: 855-865.
-
(2010)
J Infect Dis
, vol.201
, pp. 855-865
-
-
Kansal, R.G.1
Datta, V.2
Aziz, R.K.3
Abdeltawab, N.F.4
Rowe, S.5
-
45
-
-
0031656714
-
Molecular analysis of the capsule gene region of group A Streptococcus: the hasAB genes are sufficient for capsule expression
-
Ashbaugh CD, Alberti S, Wessels MR, (1998) Molecular analysis of the capsule gene region of group A Streptococcus: the hasAB genes are sufficient for capsule expression. J Bacteriol 180: 4955-4959.
-
(1998)
J Bacteriol
, vol.180
, pp. 4955-4959
-
-
Ashbaugh, C.D.1
Alberti, S.2
Wessels, M.R.3
-
46
-
-
40749113609
-
A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response
-
Sumby P, Zhang S, Whitney AR, Falugi F, Grandi G, et al. (2008) A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response. Infect Immun 76: 978-985.
-
(2008)
Infect Immun
, vol.76
, pp. 978-985
-
-
Sumby, P.1
Zhang, S.2
Whitney, A.R.3
Falugi, F.4
Grandi, G.5
-
47
-
-
0040370656
-
Protein GRAB of Streptococcus pyogenes regulates proteolysis at the bacterial surface by binding alpha2-macroglobulin
-
Rasmussen M, Muller HP, Bjorck L, (1999) Protein GRAB of Streptococcus pyogenes regulates proteolysis at the bacterial surface by binding alpha2-macroglobulin. J Biol Chem 274: 15336-15344.
-
(1999)
J Biol Chem
, vol.274
, pp. 15336-15344
-
-
Rasmussen, M.1
Muller, H.P.2
Bjorck, L.3
-
48
-
-
33846936743
-
CovR activation of the dipeptide permease promoter (PdppA) in Group A Streptococcus
-
Gusa AA, Froehlich BJ, Desai D, Stringer V, Scott JR, (2007) CovR activation of the dipeptide permease promoter (PdppA) in Group A Streptococcus. J Bacteriol 189: 1407-1416.
-
(2007)
J Bacteriol
, vol.189
, pp. 1407-1416
-
-
Gusa, A.A.1
Froehlich, B.J.2
Desai, D.3
Stringer, V.4
Scott, J.R.5
-
49
-
-
34447280868
-
Active and passive immunizations with the streptococcal esterase Sse protect mice against subcutaneous infection with group A streptococci
-
Liu M, Zhu H, Zhang J, Lei B, (2007) Active and passive immunizations with the streptococcal esterase Sse protect mice against subcutaneous infection with group A streptococci. Infect Immun 75: 3651-3657.
-
(2007)
Infect Immun
, vol.75
, pp. 3651-3657
-
-
Liu, M.1
Zhu, H.2
Zhang, J.3
Lei, B.4
-
50
-
-
0029054028
-
Molecular population genetic analysis of the streptokinase gene of Streptococcus pyogenes: mosaic alleles generated by recombination
-
Kapur V, Kanjilal S, Hamrick MR, Li LL, Whittam TS, et al. (1995) Molecular population genetic analysis of the streptokinase gene of Streptococcus pyogenes: mosaic alleles generated by recombination. Mol Microbiol 16: 509-519.
-
(1995)
Mol Microbiol
, vol.16
, pp. 509-519
-
-
Kapur, V.1
Kanjilal, S.2
Hamrick, M.R.3
Li, L.L.4
Whittam, T.S.5
-
51
-
-
0037007214
-
IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G
-
von Pawel-Rammingen U, Johansson BP, Bjorck L, (2002) IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G. EMBO J 21: 1607-1615.
-
(2002)
EMBO J
, vol.21
, pp. 1607-1615
-
-
von Pawel-Rammingen, U.1
Johansson, B.P.2
Bjorck, L.3
-
52
-
-
0033919434
-
Genetic locus for streptolysin S production by group A Streptococcus
-
Nizet V, Beall B, Bast DJ, Datta V, Kilburn L, et al. (2000) Genetic locus for streptolysin S production by group A Streptococcus. Infect Immun 68: 4245-4254.
-
(2000)
Infect Immun
, vol.68
, pp. 4245-4254
-
-
Nizet, V.1
Beall, B.2
Bast, D.J.3
Datta, V.4
Kilburn, L.5
-
53
-
-
0033722461
-
Mitogenic factor (MF) is the major DNase of serotype M89 Streptococcus pyogenes
-
Sriskandan S, Unnikrishnan M, Krausz T, Cohen J, (2000) Mitogenic factor (MF) is the major DNase of serotype M89 Streptococcus pyogenes. Microbiology 146 (Pt 11):: 2785-2792.
-
(2000)
Microbiology
, vol.146
, Issue.Pt 11
, pp. 2785-2792
-
-
Sriskandan, S.1
Unnikrishnan, M.2
Krausz, T.3
Cohen, J.4
-
54
-
-
0032476656
-
A role for trigger factor and an Rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes
-
Lyon WR, Gibson CM, Caparon MG, (1998) A role for trigger factor and an Rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes. EMBO J 17: 6263-6275.
-
(1998)
EMBO J
, vol.17
, pp. 6263-6275
-
-
Lyon, W.R.1
Gibson, C.M.2
Caparon, M.G.3
-
55
-
-
80055079778
-
Signal transduction through CsrRS confers an invasive phenotype in group A Streptococcus
-
Tran-Winkler HJ, Love JF, Gryllos I, Wessels MR, (2011) Signal transduction through CsrRS confers an invasive phenotype in group A Streptococcus. PLoS Pathog 7: e1002361.
-
(2011)
PLoS Pathog
, vol.7
-
-
Tran-Winkler, H.J.1
Love, J.F.2
Gryllos, I.3
Wessels, M.R.4
-
56
-
-
28244452053
-
Binding of the global response regulator protein CovR to the sag promoter of Streptococcus pyogenes reveals a new mode of CovR-DNA interaction
-
Gao J, Gusa AA, Scott JR, Churchward G, (2005) Binding of the global response regulator protein CovR to the sag promoter of Streptococcus pyogenes reveals a new mode of CovR-DNA interaction. J Biol Chem 280: 38948-38956.
-
(2005)
J Biol Chem
, vol.280
, pp. 38948-38956
-
-
Gao, J.1
Gusa, A.A.2
Scott, J.R.3
Churchward, G.4
-
57
-
-
19944420855
-
The CovR response regulator of group A Streptococcus (GAS) acts directly to repress its own promoter
-
Gusa AA, Scott JR, (2005) The CovR response regulator of group A Streptococcus (GAS) acts directly to repress its own promoter. Mol Microbiol 56: 1195-1207.
-
(2005)
Mol Microbiol
, vol.56
, pp. 1195-1207
-
-
Gusa, A.A.1
Scott, J.R.2
-
58
-
-
77956519362
-
Convergence of Ser/Thr and two-component signaling to coordinate expression of the dormancy regulon in Mycobacterium tuberculosis
-
Chao JD, Papavinasasundaram KG, Zheng X, Chavez-Steenbock A, Wang X, et al. (2010) Convergence of Ser/Thr and two-component signaling to coordinate expression of the dormancy regulon in Mycobacterium tuberculosis. J Biol Chem 285: 29239-29246.
-
(2010)
J Biol Chem
, vol.285
, pp. 29239-29246
-
-
Chao, J.D.1
Papavinasasundaram, K.G.2
Zheng, X.3
Chavez-Steenbock, A.4
Wang, X.5
-
59
-
-
78149342510
-
Role of acetyl-phosphate in activation of the Rrp2-RpoN-RpoS pathway in Borrelia burgdorferi
-
Xu H, Caimano MJ, Lin T, He M, Radolf JD, et al. (2010) Role of acetyl-phosphate in activation of the Rrp2-RpoN-RpoS pathway in Borrelia burgdorferi. PLoS Pathog 6: e1001104.
-
(2010)
PLoS Pathog
, vol.6
-
-
Xu, H.1
Caimano, M.J.2
Lin, T.3
He, M.4
Radolf, J.D.5
-
60
-
-
55149094071
-
The transcriptional terminator sequences downstream of the covR gene terminate covR/S operon transcription to generate covR monocistronic transcripts in Streptococcus pyogenes
-
Chiang-Ni C, Tsou CC, Lin YS, Chuang WJ, Lin MT, et al. (2008) The transcriptional terminator sequences downstream of the covR gene terminate covR/S operon transcription to generate covR monocistronic transcripts in Streptococcus pyogenes. Gene 427: 99-103.
-
(2008)
Gene
, vol.427
, pp. 99-103
-
-
Chiang-Ni, C.1
Tsou, C.C.2
Lin, Y.S.3
Chuang, W.J.4
Lin, M.T.5
-
61
-
-
84881372065
-
Protein-serine/threonine/tyrosine kinases in bacterial signaling and regulation
-
Cousin C, Derouiche A, Shi L, Pagot Y, Poncet S, et al. (2013) Protein-serine/threonine/tyrosine kinases in bacterial signaling and regulation. FEMS Microbiol Lett 346: 11-19.
-
(2013)
FEMS Microbiol Lett
, vol.346
, pp. 11-19
-
-
Cousin, C.1
Derouiche, A.2
Shi, L.3
Pagot, Y.4
Poncet, S.5
-
62
-
-
77957262988
-
Streptococcus pyogenes Ser/Thr kinase-regulated cell wall hydrolase is a cell division plane-recognizing and chain-forming virulence factor
-
Pancholi V, Boel G, Jin H, (2010) Streptococcus pyogenes Ser/Thr kinase-regulated cell wall hydrolase is a cell division plane-recognizing and chain-forming virulence factor. J Biol Chem 285: 30861-30874.
-
(2010)
J Biol Chem
, vol.285
, pp. 30861-30874
-
-
Pancholi, V.1
Boel, G.2
Jin, H.3
-
63
-
-
84859576482
-
Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP
-
Beilharz K, Novakova L, Fadda D, Branny P, Massidda O, et al. (2012) Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP. Proc Natl Acad Sci U S A 109: E905-913.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
-
-
Beilharz, K.1
Novakova, L.2
Fadda, D.3
Branny, P.4
Massidda, O.5
-
64
-
-
80855141106
-
Serine/threonine protein kinase Stk is required for virulence, stress response, and penicillin tolerance in Streptococcus pyogenes
-
Bugrysheva J, Froehlich BJ, Freiberg JA, Scott JR, (2011) Serine/threonine protein kinase Stk is required for virulence, stress response, and penicillin tolerance in Streptococcus pyogenes. Infect Immun 79: 4201-4209.
-
(2011)
Infect Immun
, vol.79
, pp. 4201-4209
-
-
Bugrysheva, J.1
Froehlich, B.J.2
Freiberg, J.A.3
Scott, J.R.4
-
65
-
-
84861214601
-
Group A Streptococcus secreted esterase hydrolyzes platelet-activating factor to impede neutrophil recruitment and facilitate innate immune evasion
-
Liu M, Zhu H, Li J, Garcia CC, Feng W, et al. (2012) Group A Streptococcus secreted esterase hydrolyzes platelet-activating factor to impede neutrophil recruitment and facilitate innate immune evasion. PLoS Pathog 8: e1002624.
-
(2012)
PLoS Pathog
, vol.8
-
-
Liu, M.1
Zhu, H.2
Li, J.3
Garcia, C.C.4
Feng, W.5
-
66
-
-
77954082501
-
Highly frequent mutations in negative regulators of multiple virulence genes in group A streptococcal toxic shock syndrome isolates
-
Ikebe T, Ato M, Matsumura T, Hasegawa H, Sata T, et al. (2010) Highly frequent mutations in negative regulators of multiple virulence genes in group A streptococcal toxic shock syndrome isolates. PLoS Pathog 6: e1000832.
-
(2010)
PLoS Pathog
, vol.6
-
-
Ikebe, T.1
Ato, M.2
Matsumura, T.3
Hasegawa, H.4
Sata, T.5
-
67
-
-
33845626641
-
How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria
-
Deutscher J, Francke C, Postma PW, (2006) How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria. Microbiol Mol Biol Rev 70: 939-1031.
-
(2006)
Microbiol Mol Biol Rev
, vol.70
, pp. 939-1031
-
-
Deutscher, J.1
Francke, C.2
Postma, P.W.3
-
68
-
-
4544356004
-
Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P
-
Schumacher MA, Allen GS, Diel M, Seidel G, Hillen W, et al. (2004) Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P. Cell 118: 731-741.
-
(2004)
Cell
, vol.118
, pp. 731-741
-
-
Schumacher, M.A.1
Allen, G.S.2
Diel, M.3
Seidel, G.4
Hillen, W.5
-
69
-
-
34248205790
-
Bacterial response regulators: versatile regulatory strategies from common domains
-
Gao R, Mack TR, Stock AM, (2007) Bacterial response regulators: versatile regulatory strategies from common domains. Trends Biochem Sci 32: 225-234.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 225-234
-
-
Gao, R.1
Mack, T.R.2
Stock, A.M.3
-
70
-
-
0032739281
-
C-terminal DNA binding stimulates N-terminal phosphorylation of the outer membrane protein regulator OmpR from Escherichia coli
-
Ames SK, Frankema N, Kenney LJ, (1999) C-terminal DNA binding stimulates N-terminal phosphorylation of the outer membrane protein regulator OmpR from Escherichia coli. Proc Natl Acad Sci U S A 96: 11792-11797.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11792-11797
-
-
Ames, S.K.1
Frankema, N.2
Kenney, L.J.3
-
71
-
-
34547743126
-
Crystal structures of the receiver domain of the response regulator PhoP from Escherichia coli in the absence and presence of the phosphoryl analog beryllofluoride
-
Bachhawat P, Stock AM, (2007) Crystal structures of the receiver domain of the response regulator PhoP from Escherichia coli in the absence and presence of the phosphoryl analog beryllofluoride. J Bacteriol 189: 5987-5995.
-
(2007)
J Bacteriol
, vol.189
, pp. 5987-5995
-
-
Bachhawat, P.1
Stock, A.M.2
-
72
-
-
0037386721
-
The CsrR/CsrS two-component system of group A Streptococcus responds to environmental Mg2+
-
Gryllos I, Levin JC, Wessels MR, (2003) The CsrR/CsrS two-component system of group A Streptococcus responds to environmental Mg2+. Proc Natl Acad Sci USA 100: 4227-4232.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4227-4232
-
-
Gryllos, I.1
Levin, J.C.2
Wessels, M.R.3
-
73
-
-
84861033764
-
Polymorphisms in regulator of protease B (RopB) alter disease phenotype and strain virulence of serotype M3 group A Streptococcus
-
Olsen RJ, Laucirica DR, Watkins ME, Feske ML, Garcia-Bustillos JR, et al. (2012) Polymorphisms in regulator of protease B (RopB) alter disease phenotype and strain virulence of serotype M3 group A Streptococcus. J Infect Dis 205: 1719-1729.
-
(2012)
J Infect Dis
, vol.205
, pp. 1719-1729
-
-
Olsen, R.J.1
Laucirica, D.R.2
Watkins, M.E.3
Feske, M.L.4
Garcia-Bustillos, J.R.5
-
74
-
-
79955485771
-
Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice
-
Carroll RK, Iii SA, Olsen RJ, Suber B, Sahasrabhojane P, et al. (2011) Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice. J Clin Invest 121: 1956-68.
-
(2011)
J Clin Invest
, vol.121
, pp. 1956-1968
-
-
Carroll, R.K.1
Iii, S.A.2
Olsen, R.J.3
Suber, B.4
Sahasrabhojane, P.5
-
75
-
-
27544511899
-
InsPecT: identification of posttranslationally modified peptides from tandem mass spectra
-
Tanner S, Shu H, Frank A, Wang LC, Zandi E, et al. (2005) InsPecT: identification of posttranslationally modified peptides from tandem mass spectra. Anal Chem 77: 4626-4639.
-
(2005)
Anal Chem
, vol.77
, pp. 4626-4639
-
-
Tanner, S.1
Shu, H.2
Frank, A.3
Wang, L.C.4
Zandi, E.5
-
76
-
-
0030960001
-
Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains
-
Lukomski S, Sreevatsan S, Amberg C, Reichardt W, Woischnik M, et al. (1997) Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains. J Clin Invest 99: 2574-2580.
-
(1997)
J Clin Invest
, vol.99
, pp. 2574-2580
-
-
Lukomski, S.1
Sreevatsan, S.2
Amberg, C.3
Reichardt, W.4
Woischnik, M.5
-
77
-
-
21144443961
-
Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques
-
Virtaneva K, Porcella SF, Graham MR, Ireland RM, Johnson CA, et al. (2005) Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques. Proc Natl Acad Sci USA 102: 9014-9019.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9014-9019
-
-
Virtaneva, K.1
Porcella, S.F.2
Graham, M.R.3
Ireland, R.M.4
Johnson, C.A.5
-
78
-
-
77958471357
-
Differential expression analysis for sequence count data
-
Anders S, Huber W, (2010) Differential expression analysis for sequence count data. Genome Biol 11: R106.
-
(2010)
Genome Biol
, vol.11
-
-
Anders, S.1
Huber, W.2
-
79
-
-
0037433040
-
Identifying differentially expressed genes using false discovery rate controlling procedures
-
Reiner A, Yekutieli D, Benjamini Y, (2003) Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics 19: 368-375.
-
(2003)
Bioinformatics
, vol.19
, pp. 368-375
-
-
Reiner, A.1
Yekutieli, D.2
Benjamini, Y.3
-
80
-
-
12644274666
-
Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus
-
Li J, Kasper DL, Ausubel FM, Rosner B, Michel JL, (1997) Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus. Proc Natl Acad Sci U S A 94: 13251-13256.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13251-13256
-
-
Li, J.1
Kasper, D.L.2
Ausubel, F.M.3
Rosner, B.4
Michel, J.L.5
|