메뉴 건너뛰기




Volumn 6, Issue 9, 2010, Pages

Role of acetyl-phosphate in activation of the Rrp2-RpoN-RpoS pathway in borrelia burgdorferi

Author keywords

[No Author keywords available]

Indexed keywords

ACETATE KINASE; ACETYL COENZYME A; ACETYL PHOSPHATE; CARBAMOYL PHOSPHATE; PHOSPHATE ACETYLTRANSFERASE; PROTEIN; PROTEIN HISTIDINE KINASE; RRP2 PROTEIN; SIGMA FACTOR RPON; SIGMA FACTOR RPOS; UNCLASSIFIED DRUG;

EID: 78149342510     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001104     Document Type: Article
Times cited : (80)

References (68)
  • 1
    • 0026314432 scopus 로고
    • Lyme borreliosis: Relation of its causative agent to its vectors and hosts in North America and Europe
    • Lane RS, Piesman J, Burgdorfer W (1991) Lyme borreliosis: relation of its causative agent to its vectors and hosts in North America and Europe. Annu Rev Entomol 36: 587-609.
    • (1991) Annu Rev Entomol , vol.36 , pp. 587-609
    • Lane, R.S.1    Piesman, J.2    Burgdorfer, W.3
  • 2
    • 34547879640 scopus 로고    scopus 로고
    • Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle
    • Caimano MJ, Iyer R, Eggers CH, Gonzalez C, Morton EA, et al. (2007) Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle. Mol Microbiol 65: 1193-1217.
    • (2007) Mol Microbiol , vol.65 , pp. 1193-1217
    • Caimano, M.J.1    Iyer, R.2    Eggers, C.H.3    Gonzalez, C.4    Morton, E.A.5
  • 4
    • 53449090658 scopus 로고    scopus 로고
    • Transcriptional interplay among the regulators Rrp2, RpoN, and RpoS in Borrelia burgdorferi
    • Ouyang Z, Blevins JS, Norgard MV (2008) Transcriptional interplay among the regulators Rrp2, RpoN, and RpoS in Borrelia burgdorferi. Microbiology 154: 2641-2658.
    • (2008) Microbiology , vol.154 , pp. 2641-2658
    • Ouyang, Z.1    Blevins, J.S.2    Norgard, M.V.3
  • 5
    • 7044233312 scopus 로고    scopus 로고
    • RpoS is not central to the general stress response in Borrelia burgdorferi but does control expression of one or more essential virulence determinants
    • Caimano MJ, Eggers CH, Hazlett KRO, Radolf JD (2004) RpoS is not central to the general stress response in Borrelia burgdorferi but does control expression of one or more essential virulence determinants. Infect Immun 72: 6433-6445.
    • (2004) Infect Immun , vol.72 , pp. 6433-6445
    • Caimano, M.J.1    Eggers, C.H.2    Hazlett, K.R.O.3    Radolf, J.D.4
  • 7
    • 34248398787 scopus 로고    scopus 로고
    • Temperature-induced regulation of RpoS by a small RNA in Borrelia burgdorferi
    • Lybecker MC, Samuels DS (2007) Temperature-induced regulation of RpoS by a small RNA in Borrelia burgdorferi. Mol Microbiol 64: 1075-1089.
    • (2007) Mol Microbiol , vol.64 , pp. 1075-1089
    • Lybecker, M.C.1    Samuels, D.S.2
  • 8
    • 0035940482 scopus 로고    scopus 로고
    • Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway
    • Hubner A, Yang X, Nolen DM, Popova TG, Cabello FC, et al. (2001) Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway. Proc Natl Acad Sci U S A 98: 12724-12729.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12724-12729
    • Hubner, A.1    Yang, X.2    Nolen, D.M.3    Popova, T.G.4    Cabello, F.C.5
  • 9
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang XF, Pal U, Alani SM, Fikrig E, Norgard MV (2004) Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J Exp Med 199: 641-648.
    • (2004) J Exp Med , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5
  • 10
    • 12144289145 scopus 로고    scopus 로고
    • Outer-surface protein C of the Lyme disease spirochete: A protein induced in ticks for infection of mammals
    • Grimm D, Tilly K, Byram R, Stewart PE, Krum JG (2004) Outer-surface protein C of the Lyme disease spirochete: A protein induced in ticks for infection of mammals. Proc Natl Acad Sci U S A 101: 3142-3147.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3142-3147
    • Grimm, D.1    Tilly, K.2    Byram, R.3    Stewart, P.E.4    Krum, J.G.5
  • 11
    • 1342332130 scopus 로고    scopus 로고
    • OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands
    • Pal U, Yang X, Chen M, Bockenstedt LK, Anderson JF, et al. (2004) OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands. J Clin Invest 113: 220-230.
    • (2004) J Clin Invest , vol.113 , pp. 220-230
    • Pal, U.1    Yang, X.2    Chen, M.3    Bockenstedt, L.K.4    Anderson, J.F.5
  • 12
    • 33646930883 scopus 로고    scopus 로고
    • Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection
    • Tilly K, Krum JG, Bestor A, Jewett MW, Grimm D, et al. (2006) Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection. Infect Immun 74: 3554-3564.
    • (2006) Infect Immun , vol.74 , pp. 3554-3564
    • Tilly, K.1    Krum, J.G.2    Bestor, A.3    Jewett, M.W.4    Grimm, D.5
  • 13
    • 55849126646 scopus 로고    scopus 로고
    • Outer Surface Protein A Protects Lyme Disease Spirochetes from Acquired Host Immunity in the Tick Vector
    • Battisti JM, Bono JL, Rosa PA, Schrumpf ME, Schwan TG, et al. (2008) Outer Surface Protein A Protects Lyme Disease Spirochetes from Acquired Host Immunity in the Tick Vector. Infect Immun 76: 5228-5237.
    • (2008) Infect Immun , vol.76 , pp. 5228-5237
    • Battisti, J.M.1    Bono, J.L.2    Rosa, P.A.3    Schrumpf, M.E.4    Schwan, T.G.5
  • 15
    • 65249171323 scopus 로고    scopus 로고
    • 54- dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner
    • 54- dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner. J Bacteriol 191: 2902-2905.
    • (2009) J Bacteriol , vol.191 , pp. 2902-2905
    • Blevins, J.S.1    Xu, H.2    He, M.3    Norgard, M.V.4    Reitzer, L.5
  • 16
    • 0034192966 scopus 로고    scopus 로고
    • The biology of enhancer-dependent transcrip-tional regulation in bacteria: Insights from genome sequences
    • Studholme DJ, Buck M (2000) The biology of enhancer-dependent transcrip-tional regulation in bacteria: insights from genome sequences. FEMS Microbiol Letts 186: 1-9.
    • (2000) FEMS Microbiol Letts , vol.186 , pp. 1-9
    • Studholme, D.J.1    Buck, M.2
  • 17
    • 0031470826 scopus 로고    scopus 로고
    • Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi
    • Fraser CM, Casjens S, Huang WM, Sutton GG, Clayton R, et al. (1997) Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390: 580-586.
    • (1997) Nature , vol.390 , pp. 580-586
    • Fraser, C.M.1    Casjens, S.2    Huang, W.M.3    Sutton, G.G.4    Clayton, R.5
  • 18
    • 0141814623 scopus 로고    scopus 로고
    • The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi
    • Yang XF, Alani SM, Norgard MV (2003) The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi. Proc Natl Acad Sci U S A 100: 11001-11006.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11001-11006
    • Yang, X.F.1    Alani, S.M.2    Norgard, M.V.3
  • 19
    • 0027248437 scopus 로고
    • Prokaryotic enhancer- binding proteins reflect eukaryote-like modularity: The puzzle of nitrogen regulatory protein C
    • North AK, Klose KE, Stedman KM, Kustu S (1993) Prokaryotic enhancer- binding proteins reflect eukaryote-like modularity: the puzzle of nitrogen regulatory protein C. J Bacteriol 175: 4267-4273.
    • (1993) J Bacteriol , vol.175 , pp. 4267-4273
    • North, A.K.1    Klose, K.E.2    Stedman, K.M.3    Kustu, S.4
  • 20
    • 51949106515 scopus 로고    scopus 로고
    • Essential role of the response regulator Rrp2 in the infectious cycle of Borrelia burgdorferi
    • He M, Ouyang Z, Xu H, Pang X, et al. (2008) Essential role of the response regulator Rrp2 in the infectious cycle of Borrelia burgdorferi. Infect Immun 76: 3844-3853.
    • (2008) Infect Immun , vol.76 , pp. 3844-3853
    • He, M.1    Ouyang, Z.2    Xu, H.3    Pang, X.4
  • 21
    • 0034035586 scopus 로고    scopus 로고
    • Two-component and phosphorelay signal transduction
    • Hoch JA (2000) Two-component and phosphorelay signal transduction. Curr Opin Microbiol 3: 165-170.
    • (2000) Curr Opin Microbiol , vol.3 , pp. 165-170
    • Hoch, J.A.1
  • 22
    • 33845640610 scopus 로고    scopus 로고
    • Stimulus Perception in Bacterial Signal-Transducing Histidine Kinases
    • Mascher T, Helmann JD, Unden G (2006) Stimulus Perception in Bacterial Signal-Transducing Histidine Kinases. Microbiol Mol Biol Rev 70: 910-938.
    • (2006) Microbiol Mol Biol Rev , vol.70 , pp. 910-938
    • Mascher, T.1    Helmann, J.D.2    Unden, G.3
  • 24
    • 12544258487 scopus 로고    scopus 로고
    • Functional characterization in vitro of all twocomponent signal transduction systems from Escherichia coli
    • Yamamoto K, Hirao K, Oshima T, Aiba H, Utsumi R, et al. (2005) Functional characterization in vitro of all twocomponent signal transduction systems from Escherichia coli. J Biol Chem 280: 1448.
    • (2005) J Biol Chem , vol.280 , pp. 1448
    • Yamamoto, K.1    Hirao, K.2    Oshima, T.3    Aiba, H.4    Utsumi, R.5
  • 25
    • 0024061466 scopus 로고
    • Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: Evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism
    • Ninfa AJ, Ninfa EG, Lupas AN, Stock A, Magasanik B (1988) Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism. Proc Natl Acad Sci U S A 85: 5492-5496.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 5492-5496
    • Ninfa, A.J.1    Ninfa, E.G.2    Lupas, A.N.3    Stock, A.4    Magasanik, B.5
  • 26
    • 0141941680 scopus 로고    scopus 로고
    • Making informed decisions: Regulatory interactions between two-component systems
    • Bijlsma JE, Groisman EA (2003) Making informed decisions: regulatory interactions between two-component systems. Trends Micro 11: 359-366.
    • (2003) Trends Micro , vol.11 , pp. 359-366
    • Bijlsma, J.E.1    Groisman, E.A.2
  • 27
    • 44449112421 scopus 로고    scopus 로고
    • Specificity in two-component signal transduction pathways
    • Laub MT, Goulian M (2007) Specificity in two-component signal transduction pathways. Annu Rev Genet 41: 121-145.
    • (2007) Annu Rev Genet , vol.41 , pp. 121-145
    • Laub, M.T.1    Goulian, M.2
  • 28
    • 0026576546 scopus 로고
    • Is cross regulation by phosphorylation of two-component response regulator proteins important in bacteria?
    • Wanner BL (1992) Is cross regulation by phosphorylation of two-component response regulator proteins important in bacteria? J Bacteriol 174: 2053-2058.
    • (1992) J Bacteriol , vol.174 , pp. 2053-2058
    • Wanner, B.L.1
  • 29
    • 0027207516 scopus 로고
    • Is acetyl phosphate a global signal in Escherichia coli?
    • McCleary WR, Stock JB, Ninfa AJ (1993) Is acetyl phosphate a global signal in Escherichia coli? J Bacteriol 175: 2793-2798.
    • (1993) J Bacteriol , vol.175 , pp. 2793-2798
    • McCleary, W.R.1    Stock, J.B.2    Ninfa, A.J.3
  • 30
    • 0026512864 scopus 로고
    • Phosphorylation of bacterial response regulator proteins by low molecular weight phospho-donors
    • Lukat GS, McCleary WR, Stock AM, Stock JB (1992) Phosphorylation of bacterial response regulator proteins by low molecular weight phospho-donors. Proc Natl Acad Sci U S A 89: 718-722.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 718-722
    • Lukat, G.S.1    McCleary, W.R.2    Stock, A.M.3    Stock, J.B.4
  • 31
    • 0027411096 scopus 로고
    • Gene regulation by phosphate in enteric bacteria
    • Wanner BL (1993) Gene regulation by phosphate in enteric bacteria. J Cell Biochem 51: 47-51.
    • (1993) J Cell Biochem , vol.51 , pp. 47-51
    • Wanner, B.L.1
  • 33
    • 77949914858 scopus 로고    scopus 로고
    • Physiologically relevant small phosphodonors link metabolism to signal transduction
    • Wolfe AJ (2010) Physiologically relevant small phosphodonors link metabolism to signal transduction. Current Opinion in Microbiology 13: 204-209.
    • (2010) Current Opinion In Microbiology , vol.13 , pp. 204-209
    • Wolfe, A.J.1
  • 34
    • 62449269945 scopus 로고    scopus 로고
    • Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions
    • Rogers EA, Terekhova D, Zhang H, Hovis KM, Schwartz I, et al. (2009) Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions. Mol Microbiol.
    • (2009) Mol Microbiol
    • Rogers, E.A.1    Terekhova, D.2    Zhang, H.3    Hovis, K.M.4    Schwartz, I.5
  • 35
    • 0036126988 scopus 로고    scopus 로고
    • Clonal Polymorphism of Borrelia burgdorferi Strain B31 MI: Implications for Mutagenesis in an Infectious Strain Background
    • Elias AF, Stewart PE, Grimm D, Caimano MJ, Eggers CH, et al. (2002) Clonal Polymorphism of Borrelia burgdorferi Strain B31 MI: Implications for Mutagenesis in an Infectious Strain Background. Infect Immun 70: 2139-2150.
    • (2002) Infect Immun , vol.70 , pp. 2139-2150
    • Elias, A.F.1    Stewart, P.E.2    Grimm, D.3    Caimano, M.J.4    Eggers, C.H.5
  • 36
    • 33846706457 scopus 로고    scopus 로고
    • Artificial regulation of ospC expression in Borrelia burgdorferi
    • Gilbert MA, Morton EA, Bundle SF, Samuels DS (2007) Artificial regulation of ospC expression in Borrelia burgdorferi Mol Microbiol 63: 1259-1273.
    • (2007) Mol Microbiol , vol.63 , pp. 1259-1273
    • Gilbert, M.A.1    Morton, E.A.2    Bundle, S.F.3    Samuels, D.S.4
  • 37
    • 0030951048 scopus 로고    scopus 로고
    • Cell-density-dependent expression of Borrelia burgdorferi lipoproteins in vitro
    • Indest KJ, Ramamoorthy R, Sole M, Gilmore RD, Johnson BJB, et al. (1997) Cell-density-dependent expression of Borrelia burgdorferi lipoproteins in vitro. Infect Immun 65: 1165-1171.
    • (1997) Infect Immun , vol.65 , pp. 1165-1171
    • Indest, K.J.1    Ramamoorthy, R.2    Sole, M.3    Gilmore, R.D.4    Johnson, B.J.B.5
  • 38
    • 0033778628 scopus 로고    scopus 로고
    • Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi
    • Yang X, Goldberg MS, Popova TG, Schoeler GB, Wikel SK, et al. (2000) Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi. Mol Microbiol 37: 1470-1479.
    • (2000) Mol Microbiol , vol.37 , pp. 1470-1479
    • Yang, X.1    Goldberg, M.S.2    Popova, T.G.3    Schoeler, G.B.4    Wikel, S.K.5
  • 40
    • 0032523936 scopus 로고    scopus 로고
    • A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state
    • Akins DR, Bourell KW, Caimano MJ, Norgard MV, Radolf JD (1998) A new animal model for studying Lyme disease spirochetes in a mammalian host-adapted state. J Clin Invest 101: 2240-2250.
    • (1998) J Clin Invest , vol.101 , pp. 2240-2250
    • Akins, D.R.1    Bourell, K.W.2    Caimano, M.J.3    Norgard, M.V.4    Radolf, J.D.5
  • 41
    • 27744482663 scopus 로고    scopus 로고
    • Alternate sigma factor RpoS is required for the in vivo-specific repression of Borrelia burgdorferi plasmid lp54-borne ospA and lp6.6 genes
    • Caimano MJ, Eggers CH, Gonzalez CA, Radolf JD (2005) Alternate sigma factor RpoS is required for the in vivo-specific repression of Borrelia burgdorferi plasmid lp54-borne ospA and lp6.6 genes. J Bacteriol 187: 7845-7852.
    • (2005) J Bacteriol , vol.187 , pp. 7845-7852
    • Caimano, M.J.1    Eggers, C.H.2    Gonzalez, C.A.3    Radolf, J.D.4
  • 42
    • 52749092408 scopus 로고    scopus 로고
    • Cultivation of Borrelia burgdorferi in dialysis membrane chambers in rat peritonea
    • Unit 12C.3
    • Caimano M (2005) Cultivation of Borrelia burgdorferi in dialysis membrane chambers in rat peritonea. Curr Protoc Microbiol 12. Unit 12C.3.
    • (2005) Curr Protoc Microbiol , vol.12
    • Caimano, M.1
  • 43
    • 0036948288 scopus 로고    scopus 로고
    • Genetics of motility and chemotaxis of a fascinating gruop of bacteria: The spirochetes
    • Charon NW, Goldstein SF (2002) Genetics of motility and chemotaxis of a fascinating gruop of bacteria: the spirochetes. Annu Rev Genet 36: 47-73.
    • (2002) Annu Rev Genet , vol.36 , pp. 47-73
    • Charon, N.W.1    Goldstein, S.F.2
  • 45
    • 0032967572 scopus 로고    scopus 로고
    • Effects of environmental pH on membrane proteins in Borrelia burgdorferi
    • Carroll JA, Garon CF, Schwan TG (1999) Effects of environmental pH on membrane proteins in Borrelia burgdorferi. Infect Immun 67: 3181-3187.
    • (1999) Infect Immun , vol.67 , pp. 3181-3187
    • Carroll, J.A.1    Garon, C.F.2    Schwan, T.G.3
  • 46
    • 17644397003 scopus 로고    scopus 로고
    • Phosphorylation-Independent Activity of Atypical Response Regulators of Helicobacter pylori
    • Schar J, Sickmann A, Beier D (2005) Phosphorylation-Independent Activity of Atypical Response Regulators of Helicobacter pylori. J Bacteriol 187: 3100-3109.
    • (2005) J Bacteriol , vol.187 , pp. 3100-3109
    • Schar, J.1    Sickmann, A.2    Beier, D.3
  • 49
    • 34547614468 scopus 로고    scopus 로고
    • The intracellular concentration of acetyl phosphate in Escherichia coli is sufficient for direct phosphorylation of two-component response regulators
    • Klein AH, Shulla A, Reimann A, Keating DH, Wolfe AJ (2007) The intracellular concentration of acetyl phosphate in Escherichia coli is sufficient for direct phosphorylation of two-component response regulators. J Bacteriol 189: 5574-5581.
    • (2007) J Bacteriol , vol.189 , pp. 5574-5581
    • Klein, A.H.1    Shulla, A.2    Reimann, A.3    Keating, D.H.4    Wolfe, A.J.5
  • 50
    • 0028828202 scopus 로고
    • Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi
    • Stevenson B, Schwan TG, Rosa PA (1995) Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi. Infect Immun 63: 4535-4539.
    • (1995) Infect Immun , vol.63 , pp. 4535-4539
    • Stevenson, B.1    Schwan, T.G.2    Rosa, P.A.3
  • 51
    • 33846247458 scopus 로고    scopus 로고
    • Borrelia burgdorferi alters its gene expression and antigenic profile in response to CO2 levels
    • Hyde JA, Trzeciakowski JP, Skare JT (2007) Borrelia burgdorferi alters its gene expression and antigenic profile in response to CO2 levels. J Bacteriol 189: 437-445.
    • (2007) J Bacteriol , vol.189 , pp. 437-445
    • Hyde, J.A.1    Trzeciakowski, J.P.2    Skare, J.T.3
  • 52
    • 0028340662 scopus 로고
    • Regulation of acetyl phosphate synthesis and degradation, and the control of flagellar expression in Escherichia coli
    • Pruss BM, Wolfe AJ (1994) Regulation of acetyl phosphate synthesis and degradation, and the control of flagellar expression in Escherichia coli. Mol Microbiol 12: 973-984.
    • (1994) Mol Microbiol , vol.12 , pp. 973-984
    • Pruss, B.M.1    Wolfe, A.J.2
  • 54
    • 72049128621 scopus 로고    scopus 로고
    • BosR (BB0647) governs virulence expression in Borrelia burgdorferi
    • Ouyang Z, Kumar M, Kariu T, Haq S, Goldberg M, et al. (2009) BosR (BB0647) governs virulence expression in Borrelia burgdorferi. Mol Microbiol 74: 1331-1343.
    • (2009) Mol Microbiol , vol.74 , pp. 1331-1343
    • Ouyang, Z.1    Kumar, M.2    Kariu, T.3    Haq, S.4    Goldberg, M.5
  • 55
    • 72049101202 scopus 로고    scopus 로고
    • The BosR regulatory protein of Borrelia burgdorferi interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Lyme disease spirochete
    • Hyde JA, Shaw DK, Smith LR, Trzeciakowski JP, Skare JT (2009) The BosR regulatory protein of Borrelia burgdorferi interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Lyme disease spirochete. Mol Microbiol 74: 1344-1355.
    • (2009) Mol Microbiol , vol.74 , pp. 1344-1355
    • Hyde, J.A.1    Shaw, D.K.2    Smith, L.R.3    Trzeciakowski, J.P.4    Skare, J.T.5
  • 56
    • 72049132926 scopus 로고    scopus 로고
    • Who is the BosR around here anyway?
    • Samuels DS, Radolf JD (2009) Who is the BosR around here anyway? Mol Microbiol 74: 1295-1299.
    • (2009) Mol Microbiol , vol.74 , pp. 1295-1299
    • Samuels, D.S.1    Radolf, J.D.2
  • 57
    • 0028842880 scopus 로고
    • Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding
    • de Silva AM, Fikrig E (1995) Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding. Am J Trop Med Hyg 53: 397-404.
    • (1995) Am J Trop Med Hyg , vol.53 , pp. 397-404
    • de Silva, A.M.1    Fikrig, E.2
  • 58
    • 0034764243 scopus 로고    scopus 로고
    • Use of quantitative PCR to measure density of Borrelia burgdorferi in the midgut and salivary glands of feeding tick vectors
    • Piesman J, Schneider BS, Zeidner NS (2001) Use of quantitative PCR to measure density of Borrelia burgdorferi in the midgut and salivary glands of feeding tick vectors. J Clin Microbiol 39: 4145-4148.
    • (2001) J Clin Microbiol , vol.39 , pp. 4145-4148
    • Piesman, J.1    Schneider, B.S.2    Zeidner, N.S.3
  • 59
    • 33947200334 scopus 로고    scopus 로고
    • Identification of an ospC operator critical for immune evasion of Borrelia burgdorferi
    • Xu Q, McShan K, Liang FT (2007) Identification of an ospC operator critical for immune evasion of Borrelia burgdorferi. Mol Microbiol 64: 220-231.
    • (2007) Mol Microbiol , vol.64 , pp. 220-231
    • Xu, Q.1    McShan, K.2    Liang, F.T.3
  • 60
    • 0029200874 scopus 로고
    • Electrotransformation of the spirochete Borrelia burgdorferi
    • Nickoloff JA, ed, 45 ed. Totowa, NJ: Humana Press
    • Samuels DS (1995) Electrotransformation of the spirochete Borrelia burgdorferi. In: Nickoloff JA, ed. Methods in molecular biology. 45 ed. Totowa, NJ: Humana Press 253-259.
    • (1995) Methods In Molecular Biology , pp. 253-259
    • Samuels, D.S.1
  • 61
    • 0035168567 scopus 로고    scopus 로고
    • Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1
    • Labandeira-Rey M, Skare JT (2001) Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1. Infect Immun 69: 446-455.
    • (2001) Infect Immun , vol.69 , pp. 446-455
    • Labandeira-Rey, M.1    Skare, J.T.2
  • 62
    • 0035010058 scopus 로고    scopus 로고
    • Analysis of mechanisms associated with loss of infectivity of clonal populations of Borrelia burgdorferi B31MI
    • McDowell JV, Sung SY, Labandeira-Rey M, Skare JT, Marconi RT (2001) Analysis of mechanisms associated with loss of infectivity of clonal populations of Borrelia burgdorferi B31MI. Infect Immun 69: 3670-3677.
    • (2001) Infect Immun , vol.69 , pp. 3670-3677
    • McDowell, J.V.1    Sung, S.Y.2    Labandeira-Rey, M.3    Skare, J.T.4    Marconi, R.T.5
  • 63
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser JE, Norris SJ (2000) Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc Natl Acad Sci U S A 97: 13865-13870.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 64
    • 8144223362 scopus 로고    scopus 로고
    • Genome-Wide Transposon Mutagenesis of Borrelia burgdorferi for Identification of Phenotypic Mutants
    • Stewart PE, Hoff J, Fischer E, Krum JG, Rosa PA (2004) Genome-Wide Transposon Mutagenesis of Borrelia burgdorferi for Identification of Phenotypic Mutants. Appl Environ Microbiol 70: 5973-5979.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 5973-5979
    • Stewart, P.E.1    Hoff, J.2    Fischer, E.3    Krum, J.G.4    Rosa, P.A.5
  • 65
    • 0029057891 scopus 로고
    • High- and low-infectivity phenotypes of clonal populations of in vitro- cultured Borrelia burgdorferi
    • Norris SJ, Howell JK, Garza SA, Ferdows MS, Barbour AG (1995) High- and low-infectivity phenotypes of clonal populations of in vitro- cultured Borrelia burgdorferi. Infect Immun 63: 2206-2212.
    • (1995) Infect Immun , vol.63 , pp. 2206-2212
    • Norris, S.J.1    Howell, J.K.2    Garza, S.A.3    Ferdows, M.S.4    Barbour, A.G.5
  • 66
    • 0032755494 scopus 로고    scopus 로고
    • Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family
    • Yang X, Popova TG, Hagman KE, Wikel SK, Schoeler GB, et al. (1999) Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family. Infect Immun 67: 6008-6018.
    • (1999) Infect Immun , vol.67 , pp. 6008-6018
    • Yang, X.1    Popova, T.G.2    Hagman, K.E.3    Wikel, S.K.4    Schoeler, G.B.5
  • 67
    • 77953944083 scopus 로고    scopus 로고
    • Characterization of the highly regulated antigen BBA05 in the enzootic cycle of Borrelia burgdorferi
    • Xu H, He M, Pang X, Xu ZC, Piesman J, Yang XF (2009) Characterization of the highly regulated antigen BBA05 in the enzootic cycle of Borrelia burgdorferi. Infect Immun 15: 1872-1887.
    • (2009) Infect Immun , vol.15 , pp. 1872-1887
    • Xu, H.1    He, M.2    Pang, X.3    Xu, Z.C.4    Piesman, J.5    Yang, X.F.6
  • 68
    • 0030034983 scopus 로고    scopus 로고
    • Cell Cycle Control by an Essential Bacterial Two-Component Signal Transduction Protein
    • Quon KC, Marczynski GT, Shapiro L (1996) Cell Cycle Control by an Essential Bacterial Two-Component Signal Transduction Protein. Cell 84: 83-93.
    • (1996) Cell , vol.84 , pp. 83-93
    • Quon, K.C.1    Marczynski, G.T.2    Shapiro, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.