Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains

Journal of Clinical Investigation

Volumn 99, Issue 11, 1997, Pages 2574-2580

  Lukomski, Slawomir ^a   Sreevatsan, Srinand ^a   Amberg, Cornelia ^b   Reichardt, Werner ^b   Woischnik, Markus ^c   Podbielski, Andreas ^c   Musser, James M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c UNIVERSITY OF ULM   (Germany)

Author keywords

Genetics; Group A Streptococcus; Streptococcal pyrogenie exotoxin B; Toxin; Virulence

Indexed keywords

CYSTEINE PROTEINASE; EXOTOXIN; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME DEFICIENCY; ENZYME INACTIVATION; GENE EXPRESSION; HOST PARASITE INTERACTION; IMMUNOBLOTTING; LETHALITY; MALE; MORTALITY; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SEROTYPE; STREPTOCOCCUS PYOGENES;

EID: 0030960001     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119445     Document Type: Article

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