Inactivation of the α C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 24, 1997, Pages 13251-13256

  Jing, L I ^a,b   Kasper, Dennis L ^a,b   Ausubel, Frederick M ^b,c   Rosner, Bernard ^a,b   Michel, James L ^a,b,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Charming Laboratory   (United States)

Author keywords

Bacterial pathogenesis; Bacterial vaccines; Streptococcus agalactiae; Surface antigens

Indexed keywords

BACTERIAL VACCINE; EPITOPE; MEMBRANE ANTIGEN; OPSONIN; PROTEIN C;

ANTIGEN EXPRESSION; ARTICLE; BACTERIAL VIRULENCE; IMMUNITY; IMMUNOBLOTTING; MORTALITY; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SOUTHERN BLOTTING; STREPTOCOCCUS AGALACTIAE; STRUCTURAL GENE;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, SURFACE; BACTERIAL PROTEINS; GENES, LETHAL; GENETIC VECTORS; MICE; MICE, KNOCKOUT; MUTAGENESIS; PHAGOCYTOSIS; PHENOTYPE; RECOMBINATION, GENETIC; STREPTOCOCCUS AGALACTIAE; VIRULENCE;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS SP. 'GROUP B';

EID: 12644274666     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.24.13251     Document Type: Article

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