Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis

Acta Neuropathologica

Volumn 127, Issue 6, 2014, Pages 845-860

  Götzl, Julia K ^a,b   Mori, Kohji ^a   Damme, Markus ^c   Fellerer, Katrin ^a   Tahirovic, Sabina ^d   Kleinberger, Gernot ^a,e,f,g   Janssens, Jonathan ^f,g   Van Der Zee, Julie ^f,g   Lang, Christina M ^a   Kremmer, Elisabeth ^d,h   Martin, Jean Jacques ^g   Engelborghs, Sebastiaan ^g   Kretzschmar, Hans A ^a   Arzberger, Thomas ^a,d,i   Van Broeckhoven, Christine ^f,g   Haass, Christian ^a,d,e   Capell, Anja ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

^d GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^e Germany 3 Munich Cluster for Systems Neurology   (Germany)

^f DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^g UNIVERSITY OF ANTWERP   (Belgium)

^h INSTITUTE OF EPIDEMIOLOGY   (Germany)

ⁱ LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cathepsin D; Frontotemporal lobar degeneration (FTLD); Lysosome; Neurodegeneration; Neuronal ceroid lipofuscinosis (NCL); Progranulin (GRN); TDP 43

Indexed keywords

CATHEPSIN D; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; PROGRANULIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SPHINGOLIPID ACTIVATOR PROTEIN; TAR DNA BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FRONTOTEMPORAL DEMENTIA; HUMAN; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; LYSOSOME STORAGE DISEASE; MOUSE; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; PRIORITY JOURNAL;

EID: 84901653647     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-014-1262-6     Document Type: Article

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