-
1
-
-
77954578417
-
Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging
-
Ahmed Z., Sheng H., Xu Y.F., Lin W.L., Innes A.E., Gass J., Yu X., Wuertzer C.A., Hou H., Chiba S., Yamanouchi K., Leissring M., Petrucelli L., Nishihara M., Hutton M.L., McGowan E., Dickson D.W., Lewis J. Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging. Am J Pathol 2010, 177:311-324.
-
(2010)
Am J Pathol
, vol.177
, pp. 311-324
-
-
Ahmed, Z.1
Sheng, H.2
Xu, Y.F.3
Lin, W.L.4
Innes, A.E.5
Gass, J.6
Yu, X.7
Wuertzer, C.A.8
Hou, H.9
Chiba, S.10
Yamanouchi, K.11
Leissring, M.12
Petrucelli, L.13
Nishihara, M.14
Hutton, M.L.15
McGowan, E.16
Dickson, D.W.17
Lewis, J.18
-
2
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai T., Hasegawa M., Akiyama H., Ikeda K., Nonaka T., Mori H., Mann D., Tsuchiya K., Yoshida M., Hashizume Y., Oda T. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 2006, 351:602-611.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
3
-
-
80855132684
-
Involvement of progranulin in the enhancement of hippocampal neurogenesis by voluntary exercise
-
Asakura R., Matsuwaki T., Shim J.H., Yamanouchi K., Nishihara M. Involvement of progranulin in the enhancement of hippocampal neurogenesis by voluntary exercise. Neuroreport 2011, 22:881-886.
-
(2011)
Neuroreport
, vol.22
, pp. 881-886
-
-
Asakura, R.1
Matsuwaki, T.2
Shim, J.H.3
Yamanouchi, K.4
Nishihara, M.5
-
4
-
-
0027159828
-
Exon/intron organization of the gene encoding the mouse epithelin/granulin precursor (acrogranin)
-
Baba T., Nemoto H., Watanabe K., Arai Y., Gerton G.L. Exon/intron organization of the gene encoding the mouse epithelin/granulin precursor (acrogranin). FEBS Lett 1993, 322:89-94.
-
(1993)
FEBS Lett
, vol.322
, pp. 89-94
-
-
Baba, T.1
Nemoto, H.2
Watanabe, K.3
Arai, Y.4
Gerton, G.L.5
-
5
-
-
33746919083
-
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
-
Baker M., Mackenzie I.R., Pickering-Brown S.M., Gass J., Rademakers R., Lindholm C., Snowden J., Adamson J., Sadovnick A.D., Rollinson S., Cannon A., Dwosh E., Neary D., Melquist S., Richardson A., Dickson D., Berger Z., Eriksen J., Robinson T., Zehr C., Dickey C.A., Crook R., McGowan E., Mann D., Boeve B., Feldman H., Hutton M. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 2006, 442:916-919.
-
(2006)
Nature
, vol.442
, pp. 916-919
-
-
Baker, M.1
Mackenzie, I.R.2
Pickering-Brown, S.M.3
Gass, J.4
Rademakers, R.5
Lindholm, C.6
Snowden, J.7
Adamson, J.8
Sadovnick, A.D.9
Rollinson, S.10
Cannon, A.11
Dwosh, E.12
Neary, D.13
Melquist, S.14
Richardson, A.15
Dickson, D.16
Berger, Z.17
Eriksen, J.18
Robinson, T.19
Zehr, C.20
Dickey, C.A.21
Crook, R.22
McGowan, E.23
Mann, D.24
Boeve, B.25
Feldman, H.26
Hutton, M.27
more..
-
6
-
-
70350322693
-
Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones
-
Barreto G., Santos-Galindo M., Diz-Chaves Y., Pernía O., Carrero P., Azcoitia I., Garcia-Segura L.M. Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones. Endocrinology 2009, 150:5010-5015.
-
(2009)
Endocrinology
, vol.150
, pp. 5010-5015
-
-
Barreto, G.1
Santos-Galindo, M.2
Diz-Chaves, Y.3
Pernía, O.4
Carrero, P.5
Azcoitia, I.6
Garcia-Segura, L.M.7
-
7
-
-
70549109118
-
The granulin gene family: from cancer to dementia
-
Bateman A., Bennett H.P. The granulin gene family: from cancer to dementia. Bioessays 2009, 31:1245-1254.
-
(2009)
Bioessays
, vol.31
, pp. 1245-1254
-
-
Bateman, A.1
Bennett, H.P.2
-
8
-
-
30144440059
-
Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders
-
Bertolino P., Deckers M., Lebrin F., ten Dijke P. Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders. Chest 2005, 128:585S-590S.
-
(2005)
Chest
, vol.128
-
-
Bertolino, P.1
Deckers, M.2
Lebrin, F.3
ten Dijke, P.4
-
9
-
-
33845768784
-
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
-
Block M.L., Zecca L., Hong J.S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 2007, 8:57-69.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 57-69
-
-
Block, M.L.1
Zecca, L.2
Hong, J.S.3
-
10
-
-
52449110477
-
Genetic variability in progranulin contributes to risk for clinically diagnosed Alzheimer disease
-
Brouwers N., Sleegers K., Engelborghs S., Maurer-Stroh S., Gijselinck I., van der Zee J., Pickut B.A., Van den Broeck M., Mattheijssens M., Peeters K., Schymkowitz J., Rousseau F., Martin J.J., Cruts M., De Deyn P.P., Van Broeckhoven C. Genetic variability in progranulin contributes to risk for clinically diagnosed Alzheimer disease. Neurology 2008, 71:656-664.
-
(2008)
Neurology
, vol.71
, pp. 656-664
-
-
Brouwers, N.1
Sleegers, K.2
Engelborghs, S.3
Maurer-Stroh, S.4
Gijselinck, I.5
van der Zee, J.6
Pickut, B.A.7
Van den Broeck, M.8
Mattheijssens, M.9
Peeters, K.10
Schymkowitz, J.11
Rousseau, F.12
Martin, J.J.13
Cruts, M.14
De Deyn, P.P.15
Van Broeckhoven, C.16
-
11
-
-
80053540582
-
Delayed inflammatory mRNA and protein expression after spinal cord injury
-
Byrnes K.R., Washington P.M., Knoblach S.M., Hoffman E., Faden A.I. Delayed inflammatory mRNA and protein expression after spinal cord injury. J Neuroinflamm 2011, 8:130.
-
(2011)
J Neuroinflamm
, vol.8
, pp. 130
-
-
Byrnes, K.R.1
Washington, P.M.2
Knoblach, S.M.3
Hoffman, E.4
Faden, A.I.5
-
12
-
-
70350618915
-
Progranulin plasma levels as potential biomarker for the identification of GRN deletion carriers. A case with atypical onset as clinical amnestic Mild Cognitive Impairment converted to Alzheimer's disease
-
Carecchio M., Fenoglio C., De Riz M., Guidi I., Comi C., Cortini F., Venturelli E., Restelli I., Cantoni C., Bresolin N., Monaco F., Scarpini E., Galimberti D. Progranulin plasma levels as potential biomarker for the identification of GRN deletion carriers. A case with atypical onset as clinical amnestic Mild Cognitive Impairment converted to Alzheimer's disease. J Neurol Sci 2009, 287:291-293.
-
(2009)
J Neurol Sci
, vol.287
, pp. 291-293
-
-
Carecchio, M.1
Fenoglio, C.2
De Riz, M.3
Guidi, I.4
Comi, C.5
Cortini, F.6
Venturelli, E.7
Restelli, I.8
Cantoni, C.9
Bresolin, N.10
Monaco, F.11
Scarpini, E.12
Galimberti, D.13
-
13
-
-
34248393103
-
Involvement of granulin in estrogen-induced neurogenesis in the adult rat hippocampus
-
Chiba S., Suzuki M., Yamanouchi K., Nishihara M. Involvement of granulin in estrogen-induced neurogenesis in the adult rat hippocampus. J Reprod Dev 2007, 53:297-307.
-
(2007)
J Reprod Dev
, vol.53
, pp. 297-307
-
-
Chiba, S.1
Suzuki, M.2
Yamanouchi, K.3
Nishihara, M.4
-
14
-
-
51349151222
-
Novel exon 1 progranulin gene variant in Alzheimer's disease
-
Cortini F., Fenoglio C., Guidi I., Venturelli E., Pomati S., Marcone A., Scalabrini D., Villa C., Clerici F., Dalla Valle E., Mariani C., Cappa S., Bresolin N., Scarpini E., Galimberti D. Novel exon 1 progranulin gene variant in Alzheimer's disease. Eur J Neurol 2008, 15:1111-1117.
-
(2008)
Eur J Neurol
, vol.15
, pp. 1111-1117
-
-
Cortini, F.1
Fenoglio, C.2
Guidi, I.3
Venturelli, E.4
Pomati, S.5
Marcone, A.6
Scalabrini, D.7
Villa, C.8
Clerici, F.9
Dalla Valle, E.10
Mariani, C.11
Cappa, S.12
Bresolin, N.13
Scarpini, E.14
Galimberti, D.15
-
15
-
-
33746910649
-
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
-
Cruts M., Gijselinck I., van der Zee J., Engelborghs S., Wils H., Pirici D., Rademakers R., Vandenberghe R., Dermaut B., Martin J.J., van Duijn C., Peeters K., Sciot R., Santens P., De Pooter T., Mattheijssens M., Van den Broeck M., Cuijt I., Vennekens K., De Deyn P.P., Kumar-Singh S., Van Broeckhoven C. Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature 2006, 442:920-924.
-
(2006)
Nature
, vol.442
, pp. 920-924
-
-
Cruts, M.1
Gijselinck, I.2
van der Zee, J.3
Engelborghs, S.4
Wils, H.5
Pirici, D.6
Rademakers, R.7
Vandenberghe, R.8
Dermaut, B.9
Martin, J.J.10
van Duijn, C.11
Peeters, K.12
Sciot, R.13
Santens, P.14
De Pooter, T.15
Mattheijssens, M.16
Van den Broeck, M.17
Cuijt, I.18
Vennekens, K.19
De Deyn, P.P.20
Kumar-Singh, S.21
Van Broeckhoven, C.22
more..
-
16
-
-
0033917655
-
Cellular localization of gene expression for progranulin
-
Daniel R., He Z., Carmichael K.P., Halper J., Bateman A. Cellular localization of gene expression for progranulin. J Histochem Cytochem 2000, 48:999-1009.
-
(2000)
J Histochem Cytochem
, vol.48
, pp. 999-1009
-
-
Daniel, R.1
He, Z.2
Carmichael, K.P.3
Halper, J.4
Bateman, A.5
-
17
-
-
0142010521
-
Lack of a direct role for macrosialin in oxidized LDL metabolism
-
de Beer M.C., Zhao Z., Webb N.R., van der Westhuyzen D.R., de Villiers W.J. Lack of a direct role for macrosialin in oxidized LDL metabolism. J Lipid Res 2003, 44:674-685.
-
(2003)
J Lipid Res
, vol.44
, pp. 674-685
-
-
de Beer, M.C.1
Zhao, Z.2
Webb, N.R.3
van der Westhuyzen, D.R.4
de Villiers, W.J.5
-
18
-
-
0242366443
-
Transforming growth factor-beta: a neuroprotective factor in cerebral ischemia
-
Dhandapani K.M., Brann D.W. Transforming growth factor-beta: a neuroprotective factor in cerebral ischemia. Cell Biochem Biophys 2003, 39:13-22.
-
(2003)
Cell Biochem Biophys
, vol.39
, pp. 13-22
-
-
Dhandapani, K.M.1
Brann, D.W.2
-
19
-
-
77957689347
-
TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke
-
Doyle K.P., Cekanaviciute E., Mamer L.E., Buckwalter M.S. TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke. J Neuroinflamm 2010, 7:62.
-
(2010)
J Neuroinflamm
, vol.7
, pp. 62
-
-
Doyle, K.P.1
Cekanaviciute, E.2
Mamer, L.E.3
Buckwalter, M.S.4
-
20
-
-
77953530644
-
Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis
-
Feng J.Q., Guo F.J., Jiang B.C., Zhang Y., Frenkel S., Wang D.W., Tang W., Xie Y., Liu C.J. Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis. FASEB J 2010, 24:1879-1892.
-
(2010)
FASEB J
, vol.24
, pp. 1879-1892
-
-
Feng, J.Q.1
Guo, F.J.2
Jiang, B.C.3
Zhang, Y.4
Frenkel, S.5
Wang, D.W.6
Tang, W.7
Xie, Y.8
Liu, C.J.9
-
21
-
-
33749011447
-
Tumor necrosis factor and its p55 and p75 receptors are not required for axonal lesion-induced microgliosis in mouse fascia dentata
-
Fenger C., Drojdahl N., Wirenfeldt M., Sylvest L., Jorgensen O.S., Meldgaard M., Lambertsen K.L., Finsen B. Tumor necrosis factor and its p55 and p75 receptors are not required for axonal lesion-induced microgliosis in mouse fascia dentata. Glia 2006, 54:591-605.
-
(2006)
Glia
, vol.54
, pp. 591-605
-
-
Fenger, C.1
Drojdahl, N.2
Wirenfeldt, M.3
Sylvest, L.4
Jorgensen, O.S.5
Meldgaard, M.6
Lambertsen, K.L.7
Finsen, B.8
-
22
-
-
81955160693
-
Core features of frontotemporal dementia recapitulated in progranulin knockout mice
-
Ghoshal N., Dearborn J.T., Wozniak D.F., Cairns N.J. Core features of frontotemporal dementia recapitulated in progranulin knockout mice. Neurobiol Dis 2012, 45:395-408.
-
(2012)
Neurobiol Dis
, vol.45
, pp. 395-408
-
-
Ghoshal, N.1
Dearborn, J.T.2
Wozniak, D.F.3
Cairns, N.J.4
-
23
-
-
84858397272
-
Immediate, but not delayed, microsurgical skull reconstruction exacerbates brain damage in experimental traumatic brain injury model
-
Glover L.E., Tajiri N., Lau T., Kaneko Y., van Loveren H., Borlongan C.V. Immediate, but not delayed, microsurgical skull reconstruction exacerbates brain damage in experimental traumatic brain injury model. PLoS One 2012, 7:e33646.
-
(2012)
PLoS One
, vol.7
-
-
Glover, L.E.1
Tajiri, N.2
Lau, T.3
Kaneko, Y.4
van Loveren, H.5
Borlongan, C.V.6
-
24
-
-
77954222578
-
Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix protein
-
Guo F., Lai Y., Tian Q., Lin E.A., Kong L., Liu C. Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix protein. Arthritis Rheum 2010, 62:2023-2036.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2023-2036
-
-
Guo, F.1
Lai, Y.2
Tian, Q.3
Lin, E.A.4
Kong, L.5
Liu, C.6
-
25
-
-
39149117362
-
Immunosuppression after traumatic or ischemic CNS damage: it is neuroprotective and illuminates the role of microglial cells
-
Hailer N.P. Immunosuppression after traumatic or ischemic CNS damage: it is neuroprotective and illuminates the role of microglial cells. Prog Neurobiol 2008, 84:211-233.
-
(2008)
Prog Neurobiol
, vol.84
, pp. 211-233
-
-
Hailer, N.P.1
-
26
-
-
0242320195
-
Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis
-
He Z., Bateman A. Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis. J Mol Med (Berl) 2003, 81:600-612.
-
(2003)
J Mol Med (Berl)
, vol.81
, pp. 600-612
-
-
He, Z.1
Bateman, A.2
-
27
-
-
0037329891
-
Progranulin is a mediator of the wound response
-
He Z., Ong C.H., Halper J., Bateman A. Progranulin is a mediator of the wound response. Nat Med 2003, 9:225-229.
-
(2003)
Nat Med
, vol.9
, pp. 225-229
-
-
He, Z.1
Ong, C.H.2
Halper, J.3
Bateman, A.4
-
28
-
-
79957817169
-
Converging perturbed microvasculature and microglial clusters characterize Alzheimer disease brain
-
Jantaratnotai N., Schwab C., Ryu J.K., McGeer P.L., McLarnon J.G. Converging perturbed microvasculature and microglial clusters characterize Alzheimer disease brain. Curr Alzheimer Res 2010, 7:625-636.
-
(2010)
Curr Alzheimer Res
, vol.7
, pp. 625-636
-
-
Jantaratnotai, N.1
Schwab, C.2
Ryu, J.K.3
McGeer, P.L.4
McLarnon, J.G.5
-
29
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
Kabashi E., Valdmanis P.N., Dion P., Spiegelman D., McConkey B.J., Vande Velde C., Bouchard J.P., Lacomblez L., Pochigaeva K., Salachas F., Pradat P.F., Camu W., Meininger V., Dupre N., Rouleau G.A. TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat Genet 2008, 40:572-574.
-
(2008)
Nat Genet
, vol.40
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Spiegelman, D.4
McConkey, B.J.5
Vande Velde, C.6
Bouchard, J.P.7
Lacomblez, L.8
Pochigaeva, K.9
Salachas, F.10
Pradat, P.F.11
Camu, W.12
Meininger, V.13
Dupre, N.14
Rouleau, G.A.15
-
30
-
-
79952712455
-
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
-
Kao A.W., Eisenhut R.J., Martens L.H., Nakamura A., Huang A., Bagley J.A., Zhou P., de Luis A., Neukomm L.J., Cabello J., Farese R.V., Kenyon C. A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proc Natl Acad Sci U S A 2011, 108:4441-4446.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 4441-4446
-
-
Kao, A.W.1
Eisenhut, R.J.2
Martens, L.H.3
Nakamura, A.4
Huang, A.5
Bagley, J.A.6
Zhou, P.7
de Luis, A.8
Neukomm, L.J.9
Cabello, J.10
Farese, R.V.11
Kenyon, C.12
-
31
-
-
35448929818
-
Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene
-
Kayasuga Y., Chiba S., Suzuki M., Kikusui T., Matsuwaki T., Yamanouchi K., Kotaki H., Horai R., Iwakura Y., Nishihara M. Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene. Behav Brain Res 2007, 185:110-118.
-
(2007)
Behav Brain Res
, vol.185
, pp. 110-118
-
-
Kayasuga, Y.1
Chiba, S.2
Suzuki, M.3
Kikusui, T.4
Matsuwaki, T.5
Yamanouchi, K.6
Kotaki, H.7
Horai, R.8
Iwakura, Y.9
Nishihara, M.10
-
32
-
-
46749083014
-
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin
-
Kessenbrock K., Fröhlich L., Sixt M., Lämmermann T., Pfister H., Bateman A., Belaaouaj A., Ring J., Ollert M., Fässler R., Jenne D.E. Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. J Clin Invest 2008, 118:2438-2447.
-
(2008)
J Clin Invest
, vol.118
, pp. 2438-2447
-
-
Kessenbrock, K.1
Fröhlich, L.2
Sixt, M.3
Lämmermann, T.4
Pfister, H.5
Bateman, A.6
Belaaouaj, A.7
Ring, J.8
Ollert, M.9
Fässler, R.10
Jenne, D.E.11
-
33
-
-
70349832717
-
Heterogeneity of microglia and TNF signaling as determinants for neuronal death or survival
-
Kraft A.D., McPherson C.A., Harry G.J. Heterogeneity of microglia and TNF signaling as determinants for neuronal death or survival. Neurotoxicology 2009, 30:785-793.
-
(2009)
Neurotoxicology
, vol.30
, pp. 785-793
-
-
Kraft, A.D.1
McPherson, C.A.2
Harry, G.J.3
-
34
-
-
0033955547
-
Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages
-
Kurushima H., Ramprasad M., Kondratenko N., Foster D.M., Quehenberger O., Steinberg D. Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages. J Leukoc Biol 2000, 67:104-108.
-
(2000)
J Leukoc Biol
, vol.67
, pp. 104-108
-
-
Kurushima, H.1
Ramprasad, M.2
Kondratenko, N.3
Foster, D.M.4
Quehenberger, O.5
Steinberg, D.6
-
35
-
-
33646164362
-
Transforming growth factor-beta regulation of immune responses
-
Li M.O., Wan Y.Y., Sanjabi S., Robertson A.K., Flavell R.A. Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol 2006, 24:99-146.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 99-146
-
-
Li, M.O.1
Wan, Y.Y.2
Sanjabi, S.3
Robertson, A.K.4
Flavell, R.A.5
-
36
-
-
69549135254
-
Neurogenesis and angiogenesis within the ipsilateral thalamus with secondary damage after focal cortical infarction in hypertensive rats
-
Ling L., Zeng J., Pei Z., Cheung R.T., Hou Q., Xing S., Zhang S. Neurogenesis and angiogenesis within the ipsilateral thalamus with secondary damage after focal cortical infarction in hypertensive rats. J Cereb Blood Flow Metab 2009, 29:1538-1546.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 1538-1546
-
-
Ling, L.1
Zeng, J.2
Pei, Z.3
Cheung, R.T.4
Hou, Q.5
Xing, S.6
Zhang, S.7
-
37
-
-
58049208298
-
The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis
-
Liu C.J. The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis. Nat Clin Pract Rheumatol 2009, 5:38-45.
-
(2009)
Nat Clin Pract Rheumatol
, vol.5
, pp. 38-45
-
-
Liu, C.J.1
-
38
-
-
1942521017
-
Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages
-
Llaverias G., Noé V., Peñuelas S., Vázquez-Carrera M., Sánchez R.M., Laguna J.C., Ciudad C.J., Alegret M. Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages. Biochem Biophys Res Commun 2004, 318:265-274.
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 265-274
-
-
Llaverias, G.1
Noé, V.2
Peñuelas, S.3
Vázquez-Carrera, M.4
Sánchez, R.M.5
Laguna, J.C.6
Ciudad, C.J.7
Alegret, M.8
-
39
-
-
77957086962
-
Role of microglia in neurotrauma
-
Loane D.J., Byrnes K.R. Role of microglia in neurotrauma. Neurotherapeutics 2010, 7:366-377.
-
(2010)
Neurotherapeutics
, vol.7
, pp. 366-377
-
-
Loane, D.J.1
Byrnes, K.R.2
-
40
-
-
72749116131
-
HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes
-
Louboutin J.P., Reyes B.A., Agrawal L., Van Bockstaele E.J., Strayer D.S. HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes. Exp Neurol 2010, 221:231-245.
-
(2010)
Exp Neurol
, vol.221
, pp. 231-245
-
-
Louboutin, J.P.1
Reyes, B.A.2
Agrawal, L.3
Van Bockstaele, E.J.4
Strayer, D.S.5
-
41
-
-
84868623124
-
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury
-
Martens L.H., Zhang J., Barmada S.J., Zhou P., Kamiya S., Sun B., Min S.W., Gan L., Finkbeiner S., Huang E.J., Farese R.V. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. J Clin Invest 2012, 122:3955-3959.
-
(2012)
J Clin Invest
, vol.122
, pp. 3955-3959
-
-
Martens, L.H.1
Zhang, J.2
Barmada, S.J.3
Zhou, P.4
Kamiya, S.5
Sun, B.6
Min, S.W.7
Gan, L.8
Finkbeiner, S.9
Huang, E.J.10
Farese, R.V.11
-
42
-
-
0034110049
-
Localization of transforming growth factor-beta1 and receptor mRNA after experimental spinal cord injury
-
McTigue D.M., Popovich P.G., Morgan T.E., Stokes B.T. Localization of transforming growth factor-beta1 and receptor mRNA after experimental spinal cord injury. Exp Neurol 2000, 163:220-230.
-
(2000)
Exp Neurol
, vol.163
, pp. 220-230
-
-
McTigue, D.M.1
Popovich, P.G.2
Morgan, T.E.3
Stokes, B.T.4
-
43
-
-
33746839790
-
Scavenger receptors in atherosclerosis: beyond lipid uptake
-
Moore K.J., Freeman M.W. Scavenger receptors in atherosclerosis: beyond lipid uptake. Arterioscler Thromb Vasc Biol 2006, 26:1702-1711.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1702-1711
-
-
Moore, K.J.1
Freeman, M.W.2
-
44
-
-
77649192710
-
Progranulin expression is upregulated after spinal contusion in mice
-
Naphade S.B., Kigerl K.A., Jakeman L.B., Kostyk S.K., Popovich P.G., Kuret J. Progranulin expression is upregulated after spinal contusion in mice. Acta Neuropathol 2010, 119:123-133.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 123-133
-
-
Naphade, S.B.1
Kigerl, K.A.2
Jakeman, L.B.3
Kostyk, S.K.4
Popovich, P.G.5
Kuret, J.6
-
45
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D.M., Kwong L.K., Truax A.C., Micsenyi M.C., Chou T.T., Bruce J., Schuck T., Grossman M., Clark C.M., McCluskey L.F., Miller B.L., Masliah E., Mackenzie I.R., Feldman H., Feiden W., Kretzschmar H.A., Trojanowski J.Q., Lee V.M. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006, 314:130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
46
-
-
0031106404
-
Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity
-
Pepper M.S. Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity. Cytokine Growth Factor Rev 1997, 8:21-43.
-
(1997)
Cytokine Growth Factor Rev
, vol.8
, pp. 21-43
-
-
Pepper, M.S.1
-
47
-
-
70349091081
-
Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models
-
Pereson S., Wils H., Kleinberger G., McGowan E., Vandewoestyne M., Van Broeck B., Joris G., Cuijt I., Deforce D., Hutton M., Van Broeckhoven C., Kumar-Singh S. Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models. J Pathol 2009, 219:173-181.
-
(2009)
J Pathol
, vol.219
, pp. 173-181
-
-
Pereson, S.1
Wils, H.2
Kleinberger, G.3
McGowan, E.4
Vandewoestyne, M.5
Van Broeck, B.6
Joris, G.7
Cuijt, I.8
Deforce, D.9
Hutton, M.10
Van Broeckhoven, C.11
Kumar-Singh, S.12
-
48
-
-
0029966853
-
Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein
-
Ramprasad M.P., Terpstra V., Kondratenko N., Quehenberger O., Steinberg D. Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc Natl Acad Sci U S A 1996, 93:14833-14838.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14833-14838
-
-
Ramprasad, M.P.1
Terpstra, V.2
Kondratenko, N.3
Quehenberger, O.4
Steinberg, D.5
-
49
-
-
0032935816
-
Determination of protein carbonyl groups by immunoblotting
-
Robinson C.E., Keshavarzian A., Pasco D.S., Frommel T.O., Winship D.H., Holmes E.W. Determination of protein carbonyl groups by immunoblotting. Anal Biochem 1999, 266:48-57.
-
(1999)
Anal Biochem
, vol.266
, pp. 48-57
-
-
Robinson, C.E.1
Keshavarzian, A.2
Pasco, D.S.3
Frommel, T.O.4
Winship, D.H.5
Holmes, E.W.6
-
50
-
-
77951664911
-
Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGFβ after vascular damage
-
Schachtrup C., Ryu J.K., Helmrick M.J., Vagena E., Galanakis D.K., Degen J.L., Margolis R.U., Akassoglou K. Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGFβ after vascular damage. J Neurosci 2010, 30:5843-5854.
-
(2010)
J Neurosci
, vol.30
, pp. 5843-5854
-
-
Schachtrup, C.1
Ryu, J.K.2
Helmrick, M.J.3
Vagena, E.4
Galanakis, D.K.5
Degen, J.L.6
Margolis, R.U.7
Akassoglou, K.8
-
51
-
-
42049120518
-
Progranulin genetic variability contributes to amyotrophic lateral sclerosis
-
Sleegers K., Brouwers N., Maurer-Stroh S., van Es M.A., Van Damme P., van Vught P.W., van der Zee J., Serneels S., De Pooter T., Van den Broeck M., Cruts M., Schymkowitz J., De Jonghe P., Rousseau F., van den Berg L.H., Robberecht W., Van Broeckhoven C. Progranulin genetic variability contributes to amyotrophic lateral sclerosis. Neurology 2008, 71:253-259.
-
(2008)
Neurology
, vol.71
, pp. 253-259
-
-
Sleegers, K.1
Brouwers, N.2
Maurer-Stroh, S.3
van Es, M.A.4
Van Damme, P.5
van Vught, P.W.6
van der Zee, J.7
Serneels, S.8
De Pooter, T.9
Van den Broeck, M.10
Cruts, M.11
Schymkowitz, J.12
De Jonghe, P.13
Rousseau, F.14
van den Berg, L.H.15
Robberecht, W.16
Van Broeckhoven, C.17
-
52
-
-
84862134180
-
Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage
-
Smith K.R., Damiano J., Franceschetti S., Carpenter S., Canafoglia L., Morbin M., Rossi G., Pareyson D., Mole S.E., Staropoli J.F., Sims K.B., Lewis J., Lin W.L., Dickson D.W., Dahl H.H., Bahlo M., Berkovic S.F. Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage. Am J Hum Genet 2012, 90:1102-1107.
-
(2012)
Am J Hum Genet
, vol.90
, pp. 1102-1107
-
-
Smith, K.R.1
Damiano, J.2
Franceschetti, S.3
Carpenter, S.4
Canafoglia, L.5
Morbin, M.6
Rossi, G.7
Pareyson, D.8
Mole, S.E.9
Staropoli, J.F.10
Sims, K.B.11
Lewis, J.12
Lin, W.L.13
Dickson, D.W.14
Dahl, H.H.15
Bahlo, M.16
Berkovic, S.F.17
-
53
-
-
0033992388
-
Astrocytes modulate macrophage phagocytosis of myelin in vitro
-
Smith M.E., Hoerner M.T. Astrocytes modulate macrophage phagocytosis of myelin in vitro. J Neuroimmunol 2000, 102:154-162.
-
(2000)
J Neuroimmunol
, vol.102
, pp. 154-162
-
-
Smith, M.E.1
Hoerner, M.T.2
-
55
-
-
79960667861
-
Deletion of the murine scavenger receptor CD68
-
Song L., Lee C., Schindler C. Deletion of the murine scavenger receptor CD68. J Lipid Res 2011, 52:1542-1550.
-
(2011)
J Lipid Res
, vol.52
, pp. 1542-1550
-
-
Song, L.1
Lee, C.2
Schindler, C.3
-
56
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Sreedharan J., Blair I.P., Tripathi V.B., Hu X., Vance C., Rogelj B., Ackerley S., Durnall J.C., Williams K.L., Buratti E., Baralle F., de Belleroche J., Mitchell J.D., Leigh P.N., Al-Chalabi A., Miller C.C., Nicholson G., Shaw C.E. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science 2008, 319:1668-1672.
-
(2008)
Science
, vol.319
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
Ackerley, S.7
Durnall, J.C.8
Williams, K.L.9
Buratti, E.10
Baralle, F.11
de Belleroche, J.12
Mitchell, J.D.13
Leigh, P.N.14
Al-Chalabi, A.15
Miller, C.C.16
Nicholson, G.17
Shaw, C.E.18
-
57
-
-
0032548759
-
Identification of sex steroid-inducible genes in the hypothalamus of neonatal rats by cDNA subtraction
-
Suzuki M., Yoshida S., Nishihara M., Takahashi M. Identification of sex steroid-inducible genes in the hypothalamus of neonatal rats by cDNA subtraction. Neurosci Lett 1998, 242:127-130.
-
(1998)
Neurosci Lett
, vol.242
, pp. 127-130
-
-
Suzuki, M.1
Yoshida, S.2
Nishihara, M.3
Takahashi, M.4
-
58
-
-
79955477738
-
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice
-
Tang W., Lu Y., Tian Q.Y., Zhang Y., Guo F.J., Liu G.Y., Syed N.M., Lai Y., Lin E.A., Kong L., Su J., Yin F., Ding A.H., Zanin-Zhorov A., Dustin M.L., Tao J., Craft J., Yin Z., Feng J.Q., Abramson S.B., Yu X.P., Liu C.J. The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science 2011, 332:478-484.
-
(2011)
Science
, vol.332
, pp. 478-484
-
-
Tang, W.1
Lu, Y.2
Tian, Q.Y.3
Zhang, Y.4
Guo, F.J.5
Liu, G.Y.6
Syed, N.M.7
Lai, Y.8
Lin, E.A.9
Kong, L.10
Su, J.11
Yin, F.12
Ding, A.H.13
Zanin-Zhorov, A.14
Dustin, M.L.15
Tao, J.16
Craft, J.17
Yin, Z.18
Feng, J.Q.19
Abramson, S.B.20
Yu, X.P.21
Liu, C.J.22
more..
-
59
-
-
44949173099
-
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
-
Town T., Laouar Y., Pittenger C., Mori T., Szekely C.A., Tan J., Duman R.S., Flavell R.A. Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nat Med 2008, 14:681-687.
-
(2008)
Nat Med
, vol.14
, pp. 681-687
-
-
Town, T.1
Laouar, Y.2
Pittenger, C.3
Mori, T.4
Szekely, C.A.5
Tan, J.6
Duman, R.S.7
Flavell, R.A.8
-
60
-
-
77954619214
-
MiR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease
-
Wang W.X., Wilfred B.R., Madathil S.K., Tang G., Hu Y., Dimayuga J., Stromberg A.J., Huang Q., Saatman K.E., Nelson P.T. MiR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease. Am J Pathol 2010, 177:334-345.
-
(2010)
Am J Pathol
, vol.177
, pp. 334-345
-
-
Wang, W.X.1
Wilfred, B.R.2
Madathil, S.K.3
Tang, G.4
Hu, Y.5
Dimayuga, J.6
Stromberg, A.J.7
Huang, Q.8
Saatman, K.E.9
Nelson, P.T.10
-
61
-
-
33751398742
-
Smad3 null mice display more rapid wound closure and reduced scar formation after a stab wound to the cerebral cortex
-
Wang Y., Moges H., Bharucha Y., Symes A. Smad3 null mice display more rapid wound closure and reduced scar formation after a stab wound to the cerebral cortex. Exp Neurol 2007, 203:168-184.
-
(2007)
Exp Neurol
, vol.203
, pp. 168-184
-
-
Wang, Y.1
Moges, H.2
Bharucha, Y.3
Symes, A.4
-
62
-
-
79651470845
-
Dynamics of dystroglycan complex proteins and laminin changes due to angiogenesis in rat cerebral hypoperfusion
-
Wappler E.A., Adorján I., Gál A., Galgóczy P., Bindics K., Nagy Z. Dynamics of dystroglycan complex proteins and laminin changes due to angiogenesis in rat cerebral hypoperfusion. Microvasc Res 2011, 81:153-159.
-
(2011)
Microvasc Res
, vol.81
, pp. 153-159
-
-
Wappler, E.A.1
Adorján, I.2
Gál, A.3
Galgóczy, P.4
Bindics, K.5
Nagy, Z.6
-
63
-
-
78649717593
-
Microglial activation state exerts a biphasic influence on brain endothelial cell proliferation by regulating the balance of TNF and TGF-β1
-
Welser J.V., Li L., Milner R. Microglial activation state exerts a biphasic influence on brain endothelial cell proliferation by regulating the balance of TNF and TGF-β1. J Neuroinflamm 2010, 7:89.
-
(2010)
J Neuroinflamm
, vol.7
, pp. 89
-
-
Welser, J.V.1
Li, L.2
Milner, R.3
-
64
-
-
0030764732
-
Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease
-
Wyss-Coray T., Masliah E., Mallory M., McConlogue L., Johnson-Wood K., Lin C., Mucke L. Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease. Nature 1997, 389:603-606.
-
(1997)
Nature
, vol.389
, pp. 603-606
-
-
Wyss-Coray, T.1
Masliah, E.2
Mallory, M.3
McConlogue, L.4
Johnson-Wood, K.5
Lin, C.6
Mucke, L.7
-
65
-
-
34249683186
-
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation
-
Xu K., Zhang Y., Ilalov K., Carlson C.S., Feng J.Q., Di Cesare P.E., Liu C.J. Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. J Biol Chem 2007, 282:11347-11355.
-
(2007)
J Biol Chem
, vol.282
, pp. 11347-11355
-
-
Xu, K.1
Zhang, Y.2
Ilalov, K.3
Carlson, C.S.4
Feng, J.Q.5
Di Cesare, P.E.6
Liu, C.J.7
-
66
-
-
76149118401
-
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
-
Yin F., Banerjee R., Thomas B., Zhou P., Qian L., Jia T., Ma X., Ma Y., Iadecola C., Beal M.F., Nathan C., Ding A. Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice. J Exp Med 2010, 207:117-128.
-
(2010)
J Exp Med
, vol.207
, pp. 117-128
-
-
Yin, F.1
Banerjee, R.2
Thomas, B.3
Zhou, P.4
Qian, L.5
Jia, T.6
Ma, X.7
Ma, Y.8
Iadecola, C.9
Beal, M.F.10
Nathan, C.11
Ding, A.12
-
67
-
-
0037074016
-
Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair
-
Zhu J., Nathan C., Jin W., Sim D., Ashcroft G.S., Wahl S.M., Lacomis L., Erdjument-Bromage H., Tempst P., Wright C.D., Ding A. Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell 2002, 111:867-878.
-
(2002)
Cell
, vol.111
, pp. 867-878
-
-
Zhu, J.1
Nathan, C.2
Jin, W.3
Sim, D.4
Ashcroft, G.S.5
Wahl, S.M.6
Lacomis, L.7
Erdjument-Bromage, H.8
Tempst, P.9
Wright, C.D.10
Ding, A.11
-
68
-
-
77955091036
-
Astrogliosis in CNS pathologies: is there a role for microglia?
-
Zhang D., Hu X., Qian L., O'Callaghan J.P., Hong J.S. Astrogliosis in CNS pathologies: is there a role for microglia?. Mol Neurobiol 2010, 41:232-241.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 232-241
-
-
Zhang, D.1
Hu, X.2
Qian, L.3
O'Callaghan, J.P.4
Hong, J.S.5
|