Lysosomal proteolysis of prosaposin, the precursor of saposins (sphingolipid activator proteins): Its mechanism and inhibition by ganglioside

Archives of Biochemistry and Biophysics

Volumn 341, Issue 1, 1997, Pages 17-24

  Hiraiwa, Masao ^a   Martin, Brian M ^b   Kishimoto, Yasuo ^a   Conner, Gregory E ^c   Tsuji, Shoji ^d   O'Brien, John S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d NIIGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D; GANGLIOSIDE; PROSAPOSIN; SPHINGOLIPID ACTIVATOR PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME SPECIFICITY; FIBROBLAST; GLYCOSYLATION; HUMAN; HUMAN CELL; HYDROLYSIS; LYSOSOME MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; STEM CELL; VIRUS EXPRESSION;

EID: 19244385377     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1997.9958     Document Type: Article

References (31)

1. Hiraiwa M., O'Brien J. S., Kishimoto Y., Galdzicka M., Fluharty A. L., Ginns E. I., Martin B. M. Arch. Biochem. Biophys. 304:1993;110-116.
2. O'Brien J. S., Kishimoto Y. FASEB J. 5:1991;301-308.
3. Kishimoto Y., Hiraiwa M., O'Brien J. S. J. Lipid Res. 33:1992;1255-1268.
4. Fijibayashi S., Wenger D. A. Biochim. Biophys. Acta. 875:1986;554-562.
5. Fijibayashi S., Wenger D. A. J. Biol. Chem. 261:1986;15339-15343.
6. Rijnboutt S., Aert H. M. F. G., Geuze H. J., Tager J. M., Strous G. J. J. Biol. Chem. 266:1991;4862-4868.
7. Ranieli E., Paton B., Poulos A. Biochem. J. 233:1986;763-772.
8. Purpura D. P., Suzuki K. Nature (London). 266:1977;553-554.
9. Roisen F. J., Bartfield H., Nagele R., Yorke G. Science. 214:1988;577-578.
10. Ando S. Neurochem. Int. 5:1983;507-537.
11. Schwartzmann G., Sandhoff K. Biochemistry. 29:1990;10865-10871.
12. Rodden F. A., Wiegandt H., Bauer B. L. J. Neurosurg. 74:1991;606-619.
13. Morimoto S., Martin B. M., Kishimoto Y., O'Brien J. S. Biochem. Biophys. Res. Commun. 156:1988;403-410.
14. Morimoto S., Martin B. M., Yamamoto Y., Kretz K. A., O'Brien J. S., Kishimoto Y. Proc. Natl. Acad. Sci. USA. 86:1989;3389-3393.
15. Soeda S., Hiraiwa M., O'Brien J. S., Kishimoto Y. J. Biol. Chem. 268:1993;18519-18523.
16. Richo G. R., Conner G. E. J. Biol. Chem. 269:1994;14806-14812.
17. Miyazaki K., Okamura N., Kishimoto Y., Lee Y. C. Biochem. J. 235:1986;755-761.
18. Stastny J. J., Kishimoto Y., O'Brien J. S., Beattie C. W. Hybridoma. 11:1992;351-359.
19. Schägger H., von Jagou G. Anal. Biochem. 166:1987;368-379.
20. Matsudaira P. J. Biol. Chem. 262:1987;10035-10038.
21. Yamamoto K., Ikehara Y., Kawamoto S., Kato K. J. Biochem. 87:1980;237-248.
22. Takahashi T., Tang J. Methods Enzymol. 80:1981;565-581.
23. Lowry O. H., Rosenbrough N. J., Farr A. L., Randall R. J. J. Biol. Chem. 193:1951;265-275.
24. Hiraiwa M., Soeda S., Kishimoto Y., O'Brien J. S. Proc. Natl. Acad. Sci. USA. 89:1992;11254-11258.
25. Kirschke H., Barrett A. J. Chemistry of Lysosomal Proteases. 1987;Academic Press, London. p. 193-238.
26. Taniike N., Inui K., Shinoda K., Okada S., Shiotani Y., Yabuuchi H. Acta Histochem. Cytochem. 21:1988;565-573.
27. Hineno T., Sano A., Kondoh K., Ueno S., Kakimoto Y., Yoshida K. Biochem. Biophys. Res. Commun. 176:1991;668-674.
28. Fu Q., Carson G. S., Hiraiwa M., Grafe M., Kishimoto Y., O'Brien J. S. J. Mol. Neurosci. 5:1994;59-67.
29. Kreda S., Fujita N., Suzuki K. Dev. Neurosci. 16:1994;90-99.
30. O'Brien J. S., Carson G. S., Seo H. C., Hiraiwa M., Kishimoto Y. Proc. Natl. Acad. Sci. USA. 91:1994;9593-9596.
31. Leonova T., Qi X.-Y., Bencosme A., Ponce E., Sun Y., Grabowski G. A. J. Biol. Chem. 271:1996;17312-17320.