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Volumn 121, Issue , 2014, Pages 383-414

Life is three dimensional-as in vitro cancer cultures should be

Author keywords

Cancer; Cancer three dimensional (3D) culture; Scaffold; Tumor microenvironment

Indexed keywords

AGAROSE; ALBUMIN; CHITOSAN; COLLAGEN; FIBRONECTIN; MACROGOL; MATRIGEL; POLYCARBONATE; POLYMACON; POLYMER; PROTEOGLYCAN;

EID: 84901508067     PISSN: 0065230X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800249-0.00009-3     Document Type: Chapter
Times cited : (40)

References (117)
  • 1
    • 33646540700 scopus 로고    scopus 로고
    • Biofabricated marine hydrozoan: A bioactive crystalline material promoting ossification of mesenchymal stem cells
    • Abramovitch-Gottlib L., Geresh S., Vago R. Biofabricated marine hydrozoan: A bioactive crystalline material promoting ossification of mesenchymal stem cells. Tissue Engineering 2006, 12(4):729-739.
    • (2006) Tissue Engineering , vol.12 , Issue.4 , pp. 729-739
    • Abramovitch-Gottlib, L.1    Geresh, S.2    Vago, R.3
  • 3
    • 84877738157 scopus 로고    scopus 로고
    • A comparison of fibrin, agarose and gellan gum hydrogels as carriers of stem cells and growth factor delivery microspheres for cartilage regeneration
    • 035004-6041/8/3/035004
    • Ahearne M., Kelly D.J. A comparison of fibrin, agarose and gellan gum hydrogels as carriers of stem cells and growth factor delivery microspheres for cartilage regeneration. Biomedical Materials (Bristol, England) 2013, 8(3):035004. 035004-6041/8/3/035004.
    • (2013) Biomedical Materials (Bristol, England) , vol.8 , Issue.3 , pp. 035004
    • Ahearne, M.1    Kelly, D.J.2
  • 4
    • 33846531356 scopus 로고    scopus 로고
    • The tumour microenvironment as a target for chemoprevention
    • Albini A., Sporn M.B. The tumour microenvironment as a target for chemoprevention. Nature Reviews. Cancer 2007, 7(2):139-147.
    • (2007) Nature Reviews. Cancer , vol.7 , Issue.2 , pp. 139-147
    • Albini, A.1    Sporn, M.B.2
  • 6
    • 79960927827 scopus 로고    scopus 로고
    • The structural, compositional and mechanical features of the calcite shell of the barnacle Tetraclita rufotincta
    • Astachov L., Nevo Z., Brosh T., Vago R. The structural, compositional and mechanical features of the calcite shell of the barnacle Tetraclita rufotincta. Journal of Structural Biology 2011, 175(3):311-318.
    • (2011) Journal of Structural Biology , vol.175 , Issue.3 , pp. 311-318
    • Astachov, L.1    Nevo, Z.2    Brosh, T.3    Vago, R.4
  • 7
    • 6544295904 scopus 로고    scopus 로고
    • Development of intracytoplasmic lumens in a colon cancer cell line cultured on a non-adhesive surface
    • Bae S.I., Kang G.H., Kim Y.I., Lee B.L., Kleinman H.K., Kim W.H. Development of intracytoplasmic lumens in a colon cancer cell line cultured on a non-adhesive surface. Cancer Biochemistry Biophysics 1999, 17(1-2):35-47.
    • (1999) Cancer Biochemistry Biophysics , vol.17 , Issue.1-2 , pp. 35-47
    • Bae, S.I.1    Kang, G.H.2    Kim, Y.I.3    Lee, B.L.4    Kleinman, H.K.5    Kim, W.H.6
  • 8
    • 26944481910 scopus 로고    scopus 로고
    • A more aggressive breast cancer spheroid model coupled to an electronic capillary sensor system for a high-content screening of cytotoxic agents in cancer therapy: 3-Dimensional in vitro tumor spheroids as a screening model
    • Bartholoma P., Impidjati, Reininger-Mack A., Zhang Z., Thielecke H., Robitzki A. A more aggressive breast cancer spheroid model coupled to an electronic capillary sensor system for a high-content screening of cytotoxic agents in cancer therapy: 3-Dimensional in vitro tumor spheroids as a screening model. Journal of Biomolecular Screening 2005, 10(7):705-714.
    • (2005) Journal of Biomolecular Screening , vol.10 , Issue.7 , pp. 705-714
    • Bartholoma, P.1    Impidjati2    Reininger-Mack, A.3    Zhang, Z.4    Thielecke, H.5    Robitzki, A.6
  • 10
    • 34648837293 scopus 로고    scopus 로고
    • Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge
    • Bokhari M., Carnachan R.J., Cameron N.R., Przyborski S.A. Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge. Journal of Anatomy 2007, 211(4):567-576.
    • (2007) Journal of Anatomy , vol.211 , Issue.4 , pp. 567-576
    • Bokhari, M.1    Carnachan, R.J.2    Cameron, N.R.3    Przyborski, S.A.4
  • 13
    • 0027301125 scopus 로고
    • Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors
    • Bringuier P.P., Umbas R., Schaafsma H.E., Karthaus H.F., Debruyne F.M., Schalken J.A. Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors. Cancer Research 1993, 53(14):3241-3245.
    • (1993) Cancer Research , vol.53 , Issue.14 , pp. 3241-3245
    • Bringuier, P.P.1    Umbas, R.2    Schaafsma, H.E.3    Karthaus, H.F.4    Debruyne, F.M.5    Schalken, J.A.6
  • 14
    • 80053603001 scopus 로고    scopus 로고
    • A multifunctional 3D co-culture system for studies of mammary tissue morphogenesis and stem cell biology
    • Campbell J.J., Davidenko N., Caffarel M.M., Cameron R.E., Watson C.J. A multifunctional 3D co-culture system for studies of mammary tissue morphogenesis and stem cell biology. PloS One 2011, 6(9):e25661.
    • (2011) PloS One , vol.6 , Issue.9
    • Campbell, J.J.1    Davidenko, N.2    Caffarel, M.M.3    Cameron, R.E.4    Watson, C.J.5
  • 15
    • 84875856207 scopus 로고    scopus 로고
    • Combination of fibrin-agarose hydrogels and adipose-derived mesenchymal stem cells for peripheral nerve regeneration
    • 026022-2560/10/2/026022
    • Carriel V., Garrido-Gomez J., Hernandez-Cortes P., Garzon I., Garcia-Garcia S., Saez-Moreno J.A., et al. Combination of fibrin-agarose hydrogels and adipose-derived mesenchymal stem cells for peripheral nerve regeneration. Journal of Neural Engineering 2013, 10(2):026022. 026022-2560/10/2/026022.
    • (2013) Journal of Neural Engineering , vol.10 , Issue.2 , pp. 026022
    • Carriel, V.1    Garrido-Gomez, J.2    Hernandez-Cortes, P.3    Garzon, I.4    Garcia-Garcia, S.5    Saez-Moreno, J.A.6
  • 16
    • 84884132367 scopus 로고    scopus 로고
    • Transplantation of autologous endothelial progenitor cells in porous PLGA scaffolds create a microenvironment for the regeneration of hyaline cartilage in rabbits
    • Chang N.J., Lam C.F., Lin C.C., Chen W.L., Li C.F., Lin Y.T., et al. Transplantation of autologous endothelial progenitor cells in porous PLGA scaffolds create a microenvironment for the regeneration of hyaline cartilage in rabbits. Osteoarthritis and Cartilage/OARS, Osteoarthritis Research Society 2013, 21:1613-1622.
    • (2013) Osteoarthritis and Cartilage/OARS, Osteoarthritis Research Society , vol.21 , pp. 1613-1622
    • Chang, N.J.1    Lam, C.F.2    Lin, C.C.3    Chen, W.L.4    Li, C.F.5    Lin, Y.T.6
  • 17
    • 0141977175 scopus 로고    scopus 로고
    • Effects of three-dimensional culturing on osteosarcoma cells grown in a fibrous matrix: Analyses of cell morphology, cell cycle, and apoptosis
    • Chen C., Chen K., Yang S.T. Effects of three-dimensional culturing on osteosarcoma cells grown in a fibrous matrix: Analyses of cell morphology, cell cycle, and apoptosis. Biotechnology Progress 2003, 19(5):1574-1582.
    • (2003) Biotechnology Progress , vol.19 , Issue.5 , pp. 1574-1582
    • Chen, C.1    Chen, K.2    Yang, S.T.3
  • 18
    • 77449111847 scopus 로고    scopus 로고
    • Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells
    • Chen C.J., Nguyen T., Shively J.E. Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells. Experimental Cell Research 2010, 316(4):638-648.
    • (2010) Experimental Cell Research , vol.316 , Issue.4 , pp. 638-648
    • Chen, C.J.1    Nguyen, T.2    Shively, J.E.3
  • 19
    • 83355163224 scopus 로고    scopus 로고
    • The enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugs
    • Chen L., Xiao Z., Meng Y., Zhao Y., Han J., Su G., et al. The enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugs. Biomaterials 2012, 33(5):1437-1444.
    • (2012) Biomaterials , vol.33 , Issue.5 , pp. 1437-1444
    • Chen, L.1    Xiao, Z.2    Meng, Y.3    Zhao, Y.4    Han, J.5    Su, G.6
  • 20
    • 0031005382 scopus 로고    scopus 로고
    • Three-dimensional endothelial-tumor epithelial cell interactions in human cervical cancers
    • Chopra V., Dinh T.V., Hannigan E.V. Three-dimensional endothelial-tumor epithelial cell interactions in human cervical cancers. In Vitro Cellular & Developmental Biology. Animal 1997, 33(6):432-442.
    • (1997) In Vitro Cellular & Developmental Biology. Animal , vol.33 , Issue.6 , pp. 432-442
    • Chopra, V.1    Dinh, T.V.2    Hannigan, E.V.3
  • 21
    • 77949580004 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma inhibits transformed growth of non-small cell lung cancer cells through selective suppression of Snail
    • Choudhary R., Li H., Winn R.A., Sorenson A.L., Weiser-Evans M.C., Nemenoff R.A. Peroxisome proliferator-activated receptor-gamma inhibits transformed growth of non-small cell lung cancer cells through selective suppression of Snail. Neoplasia (New York, N.Y.) 2010, 12(3):224-234.
    • (2010) Neoplasia (New York, N.Y.) , vol.12 , Issue.3 , pp. 224-234
    • Choudhary, R.1    Li, H.2    Winn, R.A.3    Sorenson, A.L.4    Weiser-Evans, M.C.5    Nemenoff, R.A.6
  • 22
    • 38949188565 scopus 로고    scopus 로고
    • Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity
    • David L., Dulong V., Le Cerf D., Cazin L., Lamacz M., Vannier J.P. Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity. Acta Biomaterialia 2008, 4(2):256-263.
    • (2008) Acta Biomaterialia , vol.4 , Issue.2 , pp. 256-263
    • David, L.1    Dulong, V.2    Le Cerf, D.3    Cazin, L.4    Lamacz, M.5    Vannier, J.P.6
  • 24
    • 77955506627 scopus 로고    scopus 로고
    • Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells
    • Debeb B.G., Zhang X., Krishnamurthy S., Gao H., Cohen E., Li L., et al. Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells. Molecular Cancer 2010, 9:180.
    • (2010) Molecular Cancer , vol.9 , pp. 180
    • Debeb, B.G.1    Zhang, X.2    Krishnamurthy, S.3    Gao, H.4    Cohen, E.5    Li, L.6
  • 25
    • 78149282625 scopus 로고    scopus 로고
    • Gene expression profiles in 3D tumor analogs indicate compressive strain differentially enhances metastatic potential
    • Demou Z.N. Gene expression profiles in 3D tumor analogs indicate compressive strain differentially enhances metastatic potential. Annals of Biomedical Engineering 2010, 38(11):3509-3520.
    • (2010) Annals of Biomedical Engineering , vol.38 , Issue.11 , pp. 3509-3520
    • Demou, Z.N.1
  • 26
    • 31044445103 scopus 로고    scopus 로고
    • Human neuroblastoma (SH-SY5Y) cell culture and differentiation in 3-D collagen hydrogels for cell-based biosensing
    • Desai A., Kisaalita W.S., Keith C., Wu Z.Z. Human neuroblastoma (SH-SY5Y) cell culture and differentiation in 3-D collagen hydrogels for cell-based biosensing. Biosensors & Bioelectronics 2006, 21(8):1483-1492.
    • (2006) Biosensors & Bioelectronics , vol.21 , Issue.8 , pp. 1483-1492
    • Desai, A.1    Kisaalita, W.S.2    Keith, C.3    Wu, Z.Z.4
  • 27
    • 1942518844 scopus 로고    scopus 로고
    • Characterization and evaluation of chitosan matrix for in vitro growth of MCF-7 breast cancer cell lines
    • Dhiman H.K., Ray A.R., Panda A.K. Characterization and evaluation of chitosan matrix for in vitro growth of MCF-7 breast cancer cell lines. Biomaterials 2004, 25(21):5147-5154.
    • (2004) Biomaterials , vol.25 , Issue.21 , pp. 5147-5154
    • Dhiman, H.K.1    Ray, A.R.2    Panda, A.K.3
  • 28
    • 4544382532 scopus 로고    scopus 로고
    • Three-dimensional chitosan scaffold-based MCF-7 cell culture for the determination of the cytotoxicity of tamoxifen
    • Dhiman H.K., Ray A.R., Panda A.K. Three-dimensional chitosan scaffold-based MCF-7 cell culture for the determination of the cytotoxicity of tamoxifen. Biomaterials 2005, 26(9):979-986.
    • (2005) Biomaterials , vol.26 , Issue.9 , pp. 979-986
    • Dhiman, H.K.1    Ray, A.R.2    Panda, A.K.3
  • 30
    • 85056062964 scopus 로고    scopus 로고
    • Attachment, proliferation, and chondroinduction of mesenchymal stem cells on porous chitosan-calcium phosphate scaffolds
    • Elder S., Gottipati A., Zelenka H., Bumgardner J. Attachment, proliferation, and chondroinduction of mesenchymal stem cells on porous chitosan-calcium phosphate scaffolds. The Open Orthopaedics Journal 2013, 7:275-281.
    • (2013) The Open Orthopaedics Journal , vol.7 , pp. 275-281
    • Elder, S.1    Gottipati, A.2    Zelenka, H.3    Bumgardner, J.4
  • 34
    • 84885092167 scopus 로고    scopus 로고
    • Improvement in the quality of heterotopic allotransplanted mouse ovarian tissues with basic fibroblast growth factor and fibrin hydrogel
    • Gao J.M., Yan J., Li R., Li M., Yan L.Y., Wang T.R., et al. Improvement in the quality of heterotopic allotransplanted mouse ovarian tissues with basic fibroblast growth factor and fibrin hydrogel. Human Reproduction (Oxford, England) 2013, 28:2784-2793.
    • (2013) Human Reproduction (Oxford, England) , vol.28 , pp. 2784-2793
    • Gao, J.M.1    Yan, J.2    Li, R.3    Li, M.4    Yan, L.Y.5    Wang, T.R.6
  • 36
    • 21644487903 scopus 로고    scopus 로고
    • Three-dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study
    • Ghosh S., Spagnoli G.C., Martin I., Ploegert S., Demougin P., Heberer M., et al. Three-dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study. Journal of Cellular Physiology 2005, 204(2):522-531.
    • (2005) Journal of Cellular Physiology , vol.204 , Issue.2 , pp. 522-531
    • Ghosh, S.1    Spagnoli, G.C.2    Martin, I.3    Ploegert, S.4    Demougin, P.5    Heberer, M.6
  • 37
    • 42249095831 scopus 로고    scopus 로고
    • Increased nanoparticle penetration in collagenase-treated multicellular spheroids
    • Goodman T.T., Olive P.L., Pun S.H. Increased nanoparticle penetration in collagenase-treated multicellular spheroids. International Journal of Nanomedicine 2007, 2(2):265-274.
    • (2007) International Journal of Nanomedicine , vol.2 , Issue.2 , pp. 265-274
    • Goodman, T.T.1    Olive, P.L.2    Pun, S.H.3
  • 38
    • 79955797830 scopus 로고    scopus 로고
    • Spheroid formation and expression of liver-specific functions of human hepatocellular carcinoma-derived FLC-4 cells cultured in lactose-silk fibroin conjugate sponges
    • Gotoh Y., Ishizuka Y., Matsuura T., Niimi S. Spheroid formation and expression of liver-specific functions of human hepatocellular carcinoma-derived FLC-4 cells cultured in lactose-silk fibroin conjugate sponges. Biomacromolecules 2011, 12(5):1532-1539.
    • (2011) Biomacromolecules , vol.12 , Issue.5 , pp. 1532-1539
    • Gotoh, Y.1    Ishizuka, Y.2    Matsuura, T.3    Niimi, S.4
  • 39
    • 57549100212 scopus 로고    scopus 로고
    • The role of aragonite matrix surface chemistry on the chondrogenic differentiation of mesenchymal stem cells
    • Gross-Aviv T., Vago R. The role of aragonite matrix surface chemistry on the chondrogenic differentiation of mesenchymal stem cells. Biomaterials 2009, 30(5):770-779.
    • (2009) Biomaterials , vol.30 , Issue.5 , pp. 770-779
    • Gross-Aviv, T.1    Vago, R.2
  • 40
    • 69249230753 scopus 로고    scopus 로고
    • Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells
    • Gurski L.A., Jha A.K., Zhang C., Jia X., Farach-Carson M.C. Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells. Biomaterials 2009, 30(30):6076-6085.
    • (2009) Biomaterials , vol.30 , Issue.30 , pp. 6076-6085
    • Gurski, L.A.1    Jha, A.K.2    Zhang, C.3    Jia, X.4    Farach-Carson, M.C.5
  • 42
    • 24944436269 scopus 로고    scopus 로고
    • Cell tension, matrix mechanics, and cancer development
    • Huang S., Ingber D.E. Cell tension, matrix mechanics, and cancer development. Cancer cell 2005, 8(3):175-176.
    • (2005) Cancer cell , vol.8 , Issue.3 , pp. 175-176
    • Huang, S.1    Ingber, D.E.2
  • 43
    • 77956399506 scopus 로고    scopus 로고
    • Matrigel: A complex protein mixture required for optimal growth of cell culture
    • Hughes C.S., Postovit L.M., Lajoie G.A. Matrigel: A complex protein mixture required for optimal growth of cell culture. Proteomics 2010, 10(9):1886-1890.
    • (2010) Proteomics , vol.10 , Issue.9 , pp. 1886-1890
    • Hughes, C.S.1    Postovit, L.M.2    Lajoie, G.A.3
  • 44
    • 33645837060 scopus 로고    scopus 로고
    • Simulated weightlessness changes the cytoskeleton and extracellular matrix proteins in papillary thyroid carcinoma cells
    • Infanger M., Kossmehl P., Shakibaei M., Bauer J., Kossmehl-Zorn S., Cogoli A., et al. Simulated weightlessness changes the cytoskeleton and extracellular matrix proteins in papillary thyroid carcinoma cells. Cell and Tissue Research 2006, 324(2):267-277.
    • (2006) Cell and Tissue Research , vol.324 , Issue.2 , pp. 267-277
    • Infanger, M.1    Kossmehl, P.2    Shakibaei, M.3    Bauer, J.4    Kossmehl-Zorn, S.5    Cogoli, A.6
  • 46
    • 84855568780 scopus 로고    scopus 로고
    • Modulation of tumor cell survival, proliferation, and differentiation by the peptide derived from Tenascin-C: Implication of beta1-integrin activation
    • Iyoda T., Fukai F. Modulation of tumor cell survival, proliferation, and differentiation by the peptide derived from Tenascin-C: Implication of beta1-integrin activation. International Journal of Cell Biology 2012, 2012:647594.
    • (2012) International Journal of Cell Biology , vol.2012 , pp. 647594
    • Iyoda, T.1    Fukai, F.2
  • 49
    • 67649878833 scopus 로고    scopus 로고
    • Cryopreservable and tumorigenic three-dimensional tumor culture in porous poly(lactic-co-glycolic acid) microsphere
    • Kang S.W., Bae Y.H. Cryopreservable and tumorigenic three-dimensional tumor culture in porous poly(lactic-co-glycolic acid) microsphere. Biomaterials 2009, 30(25):4227-4232.
    • (2009) Biomaterials , vol.30 , Issue.25 , pp. 4227-4232
    • Kang, S.W.1    Bae, Y.H.2
  • 50
    • 84872491549 scopus 로고    scopus 로고
    • Developmental signaling pathways in cancer stem cells of solid tumors
    • Karamboulas C., Ailles L. Developmental signaling pathways in cancer stem cells of solid tumors. Biochimica et Biophysica Acta 2013, 1830:2481-2495.
    • (2013) Biochimica et Biophysica Acta , vol.1830 , pp. 2481-2495
    • Karamboulas, C.1    Ailles, L.2
  • 51
    • 80053155728 scopus 로고    scopus 로고
    • Epigenetic regulation of cellular adhesion in cancer
    • Katto J., Mahlknecht U. Epigenetic regulation of cellular adhesion in cancer. Carcinogenesis 2011, 32(10):1414-1418.
    • (2011) Carcinogenesis , vol.32 , Issue.10 , pp. 1414-1418
    • Katto, J.1    Mahlknecht, U.2
  • 52
    • 34548274060 scopus 로고    scopus 로고
    • Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum
    • Kenny H.A., Krausz T., Yamada S.D., Lengyel E. Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum. International Journal of Cancer/Journal international du Cancer 2007, 121(7):1463-1472.
    • (2007) International Journal of Cancer/Journal international du Cancer , vol.121 , Issue.7 , pp. 1463-1472
    • Kenny, H.A.1    Krausz, T.2    Yamada, S.D.3    Lengyel, E.4
  • 54
    • 23844460881 scopus 로고    scopus 로고
    • Three-dimensional tissue culture models in cancer biology
    • Kim J.B. Three-dimensional tissue culture models in cancer biology. Seminars in Cancer Biology 2005, 15(5):365-377.
    • (2005) Seminars in Cancer Biology , vol.15 , Issue.5 , pp. 365-377
    • Kim, J.B.1
  • 55
    • 3042667195 scopus 로고    scopus 로고
    • Three-dimensional in vitro tissue culture models of breast cancer-A review
    • Kim J.B., Stein R., O'Hare M.J. Three-dimensional in vitro tissue culture models of breast cancer-A review. Breast Cancer Research and Treatment 2004, 85(3):281-291.
    • (2004) Breast Cancer Research and Treatment , vol.85 , Issue.3 , pp. 281-291
    • Kim, J.B.1    Stein, R.2    O'Hare, M.J.3
  • 57
    • 0025135443 scopus 로고
    • Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments
    • Koide N., Sakaguchi K., Koide Y., Asano K., Kawaguchi M., Matsushima H., et al. Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments. Experimental Cell Research 1990, 186(2):227-235.
    • (1990) Experimental Cell Research , vol.186 , Issue.2 , pp. 227-235
    • Koide, N.1    Sakaguchi, K.2    Koide, Y.3    Asano, K.4    Kawaguchi, M.5    Matsushima, H.6
  • 58
    • 78149462058 scopus 로고    scopus 로고
    • Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells
    • Kumar A., Xu J., Brady S., Gao H., Yu D., Reuben J., et al. Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells. PloS One 2010, 5(10):e13390.
    • (2010) PloS One , vol.5 , Issue.10
    • Kumar, A.1    Xu, J.2    Brady, S.3    Gao, H.4    Yu, D.5    Reuben, J.6
  • 59
    • 54249100840 scopus 로고    scopus 로고
    • Three-dimensional neuroblastoma cell culture: Proteomic analysis between monolayer and multicellular tumor spheroids
    • Kumar H.R., Zhong X., Hoelz D.J., Rescorla F.J., Hickey R.J., Malkas L.H., et al. Three-dimensional neuroblastoma cell culture: Proteomic analysis between monolayer and multicellular tumor spheroids. Pediatric Surgery International 2008, 24(11):1229-1234.
    • (2008) Pediatric Surgery International , vol.24 , Issue.11 , pp. 1229-1234
    • Kumar, H.R.1    Zhong, X.2    Hoelz, D.J.3    Rescorla, F.J.4    Hickey, R.J.5    Malkas, L.H.6
  • 60
    • 84884813681 scopus 로고    scopus 로고
    • A silk fibroin based hepatocarcinoma model and the assessment of the drug response in hyaluronan-binding protein 1 overexpressed HepG2 cells
    • Kundu B., Saha P., Datta K., Kundu S.C. A silk fibroin based hepatocarcinoma model and the assessment of the drug response in hyaluronan-binding protein 1 overexpressed HepG2 cells. Biomaterials 2013, 34:9462-9474.
    • (2013) Biomaterials , vol.34 , pp. 9462-9474
    • Kundu, B.1    Saha, P.2    Datta, K.3    Kundu, S.C.4
  • 62
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • Lee G.Y., Kenny P.A., Lee E.H., Bissell M.J. Three-dimensional culture models of normal and malignant breast epithelial cells. Nature Methods 2007, 4(4):359-365.
    • (2007) Nature Methods , vol.4 , Issue.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4
  • 64
    • 34249883830 scopus 로고    scopus 로고
    • Genomic and morphological changes of neuroblastoma cells in response to three-dimensional matrices
    • Li G.N., Livi L.L., Gourd C.M., Deweerd E.S., Hoffman-Kim D. Genomic and morphological changes of neuroblastoma cells in response to three-dimensional matrices. Tissue Engineering 2007, 13(5):1035-1047.
    • (2007) Tissue Engineering , vol.13 , Issue.5 , pp. 1035-1047
    • Li, G.N.1    Livi, L.L.2    Gourd, C.M.3    Deweerd, E.S.4    Hoffman-Kim, D.5
  • 65
    • 59249106851 scopus 로고    scopus 로고
    • Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro
    • Li C.L., Tian T., Nan K.J., Zhao N., Guo Y.H., Cui J., et al. Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro. Oncology Reports 2008, 20(6):1465-1471.
    • (2008) Oncology Reports , vol.20 , Issue.6 , pp. 1465-1471
    • Li, C.L.1    Tian, T.2    Nan, K.J.3    Zhao, N.4    Guo, Y.H.5    Cui, J.6
  • 66
    • 84888306873 scopus 로고    scopus 로고
    • Tissue-engineered mesh for pelvic floor reconstruction fabricated from silk fibroin scaffold with adipose-derived mesenchymal stem cells
    • Li Q., Wang J., Liu H., Xie B., Wei L. Tissue-engineered mesh for pelvic floor reconstruction fabricated from silk fibroin scaffold with adipose-derived mesenchymal stem cells. Cell and Tissue Research 2013, 354:471-480.
    • (2013) Cell and Tissue Research , vol.354 , pp. 471-480
    • Li, Q.1    Wang, J.2    Liu, H.3    Xie, B.4    Wei, L.5
  • 67
    • 58749093939 scopus 로고    scopus 로고
    • Recent advances in three-dimensional multicellular spheroid culture for biomedical research
    • Lin R.Z., Chang H.Y. Recent advances in three-dimensional multicellular spheroid culture for biomedical research. Biotechnology Journal 2008, 3(9-10):1172-1184.
    • (2008) Biotechnology Journal , vol.3 , Issue.9-10 , pp. 1172-1184
    • Lin, R.Z.1    Chang, H.Y.2
  • 70
    • 77956187576 scopus 로고    scopus 로고
    • Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells
    • Loessner D., Stok K.S., Lutolf M.P., Hutmacher D.W., Clements J.A., Rizzi S.C. Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells. Biomaterials 2010, 31(32):8494-8506.
    • (2010) Biomaterials , vol.31 , Issue.32 , pp. 8494-8506
    • Loessner, D.1    Stok, K.S.2    Lutolf, M.P.3    Hutmacher, D.W.4    Clements, J.A.5    Rizzi, S.C.6
  • 71
    • 1142293806 scopus 로고    scopus 로고
    • Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells
    • Luo J., Yang S.T. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnology Progress 2004, 20(1):306-315.
    • (2004) Biotechnology Progress , vol.20 , Issue.1 , pp. 306-315
    • Luo, J.1    Yang, S.T.2
  • 72
    • 70349306322 scopus 로고    scopus 로고
    • Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma
    • Marrero B., Messina J.L., Heller R. Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma. In Vitro Cellular & Developmental Biology. Animal 2009, 45(9):523-534.
    • (2009) In Vitro Cellular & Developmental Biology. Animal , vol.45 , Issue.9 , pp. 523-534
    • Marrero, B.1    Messina, J.L.2    Heller, R.3
  • 73
    • 80051905722 scopus 로고    scopus 로고
    • The liquid overlay technique is the key to formation of co-culture spheroids consisting of primary osteoblasts, fibroblasts and endothelial cells
    • Metzger W., Sossong D., Bachle A., Putz N., Wennemuth G., Pohlemann T., et al. The liquid overlay technique is the key to formation of co-culture spheroids consisting of primary osteoblasts, fibroblasts and endothelial cells. Cytotherapy 2011, 13(8):1000-1012.
    • (2011) Cytotherapy , vol.13 , Issue.8 , pp. 1000-1012
    • Metzger, W.1    Sossong, D.2    Bachle, A.3    Putz, N.4    Wennemuth, G.5    Pohlemann, T.6
  • 74
    • 84875407870 scopus 로고    scopus 로고
    • Generation of multicellular tumor spheroids of breast cancer cells: How to go three-dimensional
    • Nagelkerke A., Bussink J., Sweep F.C., Span P.N. Generation of multicellular tumor spheroids of breast cancer cells: How to go three-dimensional. Analytical Biochemistry 2013, 437(1):17-19.
    • (2013) Analytical Biochemistry , vol.437 , Issue.1 , pp. 17-19
    • Nagelkerke, A.1    Bussink, J.2    Sweep, F.C.3    Span, P.N.4
  • 77
    • 77955692939 scopus 로고    scopus 로고
    • Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts
    • Olsen C.J., Moreira J., Lukanidin E.M., Ambartsumian N.S. Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts. BMC Cancer 2010, 10:444.
    • (2010) BMC Cancer , vol.10 , pp. 444
    • Olsen, C.J.1    Moreira, J.2    Lukanidin, E.M.3    Ambartsumian, N.S.4
  • 78
    • 79960843767 scopus 로고    scopus 로고
    • The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture
    • Pageau S.C., Sazonova O.V., Wong J.Y., Soto A.M., Sonnenschein C. The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture. Biomaterials 2011, 32(29):7169-7180.
    • (2011) Biomaterials , vol.32 , Issue.29 , pp. 7169-7180
    • Pageau, S.C.1    Sazonova, O.V.2    Wong, J.Y.3    Soto, A.M.4    Sonnenschein, C.5
  • 79
    • 84901503246 scopus 로고    scopus 로고
    • Evaluation of co-cultured CL-1 hepatocytes and hepatic stellate cells in rotatory cell culture system
    • Pan K., Zhou H., Zhang Z., Gao Y., Xu X. Evaluation of co-cultured CL-1 hepatocytes and hepatic stellate cells in rotatory cell culture system. Nan fang yi ke da xue xue bao 2013, 33(6):902-905.
    • (2013) Nan fang yi ke da xue xue bao , vol.33 , Issue.6 , pp. 902-905
    • Pan, K.1    Zhou, H.2    Zhang, Z.3    Gao, Y.4    Xu, X.5
  • 80
    • 84881601568 scopus 로고    scopus 로고
    • Anionic carbohydrate-containing chitosan scaffolds for bone regeneration
    • Park H., Choi B., Nguyen J., Fan J., Shafi S., Klokkevold P., et al. Anionic carbohydrate-containing chitosan scaffolds for bone regeneration. Carbohydrate Polymers 2013, 97(2):587-596.
    • (2013) Carbohydrate Polymers , vol.97 , Issue.2 , pp. 587-596
    • Park, H.1    Choi, B.2    Nguyen, J.3    Fan, J.4    Shafi, S.5    Klokkevold, P.6
  • 81
    • 77953649638 scopus 로고    scopus 로고
    • Relationships between degradability of silk scaffolds and osteogenesis
    • Park S.H., Gil E.S., Kim H.J., Lee K., Kaplan D.L. Relationships between degradability of silk scaffolds and osteogenesis. Biomaterials 2010, 31(24):6162-6172.
    • (2010) Biomaterials , vol.31 , Issue.24 , pp. 6162-6172
    • Park, S.H.1    Gil, E.S.2    Kim, H.J.3    Lee, K.4    Kaplan, D.L.5
  • 82
    • 77749249701 scopus 로고    scopus 로고
    • A novel 3-D mineralized tumor model to study breast cancer bone metastasis
    • Pathi S.P., Kowalczewski C., Tadipatri R., Fischbach C. A novel 3-D mineralized tumor model to study breast cancer bone metastasis. PloS One 2010, 5(1):e8849.
    • (2010) PloS One , vol.5 , Issue.1
    • Pathi, S.P.1    Kowalczewski, C.2    Tadipatri, R.3    Fischbach, C.4
  • 84
    • 45549107567 scopus 로고    scopus 로고
    • Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner
    • Quiros R.M., Valianou M., Kwon Y., Brown K.M., Godwin A.K., Cukierman E. Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner. Gynecologic Oncology 2008, 110(1):99-109.
    • (2008) Gynecologic Oncology , vol.110 , Issue.1 , pp. 99-109
    • Quiros, R.M.1    Valianou, M.2    Kwon, Y.3    Brown, K.M.4    Godwin, A.K.5    Cukierman, E.6
  • 86
    • 84856012333 scopus 로고    scopus 로고
    • Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma
    • Rasmuson A., Kock A., Fuskevag O.M., Kruspig B., Simon-Santamaria J., Gogvadze V., et al. Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma. PloS One 2012, 7(1):e29331.
    • (2012) PloS One , vol.7 , Issue.1
    • Rasmuson, A.1    Kock, A.2    Fuskevag, O.M.3    Kruspig, B.4    Simon-Santamaria, J.5    Gogvadze, V.6
  • 87
    • 40249109986 scopus 로고    scopus 로고
    • Compressive forces induce osteogenic gene expression in calvarial osteoblasts
    • Rath B., Nam J., Knobloch T.J., Lannutti J.J., Agarwal S. Compressive forces induce osteogenic gene expression in calvarial osteoblasts. Journal of Biomechanics 2008, 41(5):1095-1103.
    • (2008) Journal of Biomechanics , vol.41 , Issue.5 , pp. 1095-1103
    • Rath, B.1    Nam, J.2    Knobloch, T.J.3    Lannutti, J.J.4    Agarwal, S.5
  • 90
    • 84883255557 scopus 로고    scopus 로고
    • Poly(lactide-co-glycolide acid)/biphasic calcium phosphate composite coating on a porous scaffold to deliver simvastatin for bone tissue engineering
    • Sadiasa A., Kim M.S., Lee B.T. Poly(lactide-co-glycolide acid)/biphasic calcium phosphate composite coating on a porous scaffold to deliver simvastatin for bone tissue engineering. Journal of Drug Targeting 2013, 21(8):719-729.
    • (2013) Journal of Drug Targeting , vol.21 , Issue.8 , pp. 719-729
    • Sadiasa, A.1    Kim, M.S.2    Lee, B.T.3
  • 91
    • 68749083668 scopus 로고    scopus 로고
    • Three-dimensional Huh7 cell culture system for the study of Hepatitis C virus infection
    • Sainz B., TenCate V., Uprichard S.L. Three-dimensional Huh7 cell culture system for the study of Hepatitis C virus infection. Virology Journal 2009, 6:103.
    • (2009) Virology Journal , vol.6 , pp. 103
    • Sainz, B.1    TenCate, V.2    Uprichard, S.L.3
  • 92
    • 77953962165 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in regulating neuronal and nonneuronal cell invasion into PEGylated fibrinogen hydrogels
    • Sarig-Nadir O., Seliktar D. The role of matrix metalloproteinases in regulating neuronal and nonneuronal cell invasion into PEGylated fibrinogen hydrogels. Biomaterials 2010, 31(25):6411-6416.
    • (2010) Biomaterials , vol.31 , Issue.25 , pp. 6411-6416
    • Sarig-Nadir, O.1    Seliktar, D.2
  • 93
    • 77952847488 scopus 로고    scopus 로고
    • Three-dimensional cell growth confers radioresistance by chromatin density modification
    • Storch K., Eke I., Borgmann K., Krause M., Richter C., Becker K., et al. Three-dimensional cell growth confers radioresistance by chromatin density modification. Cancer Research 2010, 70(10):3925-3934.
    • (2010) Cancer Research , vol.70 , Issue.10 , pp. 3925-3934
    • Storch, K.1    Eke, I.2    Borgmann, K.3    Krause, M.4    Richter, C.5    Becker, K.6
  • 95
    • 65649133932 scopus 로고    scopus 로고
    • A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs
    • Sung J.H., Shuler M.L. A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs. Lab On a Chip 2009, 9(10):1385-1394.
    • (2009) Lab On a Chip , vol.9 , Issue.10 , pp. 1385-1394
    • Sung, J.H.1    Shuler, M.L.2
  • 96
    • 34249864531 scopus 로고    scopus 로고
    • Biomechanics and biophysics of cancer cells
    • Suresh S. Biomechanics and biophysics of cancer cells. Acta Biomaterialia 2007, 3(4):413-438.
    • (2007) Acta Biomaterialia , vol.3 , Issue.4 , pp. 413-438
    • Suresh, S.1
  • 98
    • 80051804176 scopus 로고    scopus 로고
    • 3D in vitro bioengineered tumors based on collagen I hydrogels
    • Szot C.S., Buchanan C.F., Freeman J.W., Rylander M.N. 3D in vitro bioengineered tumors based on collagen I hydrogels. Biomaterials 2011, 32(31):7905-7912.
    • (2011) Biomaterials , vol.32 , Issue.31 , pp. 7905-7912
    • Szot, C.S.1    Buchanan, C.F.2    Freeman, J.W.3    Rylander, M.N.4
  • 99
    • 79959884148 scopus 로고    scopus 로고
    • Three-dimensional porous silk tumor constructs in the approximation of in vivo osteosarcoma physiology
    • Tan P.H., Aung K.Z., Toh S.L., Goh J.C., Nathan S.S. Three-dimensional porous silk tumor constructs in the approximation of in vivo osteosarcoma physiology. Biomaterials 2011, 32(26):6131-6137.
    • (2011) Biomaterials , vol.32 , Issue.26 , pp. 6131-6137
    • Tan, P.H.1    Aung, K.Z.2    Toh, S.L.3    Goh, J.C.4    Nathan, S.S.5
  • 100
    • 78049345305 scopus 로고    scopus 로고
    • Mechanical force affects expression of an in vitro metastasis-like phenotype in HCT-8 cells
    • Tang X., Kuhlenschmidt T.B., Zhou J., Bell P., Wang F., Kuhlenschmidt M.S., et al. Mechanical force affects expression of an in vitro metastasis-like phenotype in HCT-8 cells. Biophysical Journal 2010, 99(8):2460-2469.
    • (2010) Biophysical Journal , vol.99 , Issue.8 , pp. 2460-2469
    • Tang, X.1    Kuhlenschmidt, T.B.2    Zhou, J.3    Bell, P.4    Wang, F.5    Kuhlenschmidt, M.S.6
  • 101
    • 34948873590 scopus 로고    scopus 로고
    • Differentiation of multipotent mesenchymal stromal cells of bone marrow into cells of cartilage tissue by culturing in three-dementia OPLA scaffolds
    • Tepliashin A.S., Korzhikova S.V., Sharifullina S.Z., Rostovskaia M.S., Chupikova N.I., Vasiunina N.I., et al. Differentiation of multipotent mesenchymal stromal cells of bone marrow into cells of cartilage tissue by culturing in three-dementia OPLA scaffolds. Tsitologiia 2007, 49(7):544-551.
    • (2007) Tsitologiia , vol.49 , Issue.7 , pp. 544-551
    • Tepliashin, A.S.1    Korzhikova, S.V.2    Sharifullina, S.Z.3    Rostovskaia, M.S.4    Chupikova, N.I.5    Vasiunina, N.I.6
  • 103
    • 9644255820 scopus 로고    scopus 로고
    • Multi-channel 3-D cell culture device integrated on a silicon chip for anticancer drug sensitivity test
    • Torisawa Y.S., Shiku H., Yasukawa T., Nishizawa M., Matsue T. Multi-channel 3-D cell culture device integrated on a silicon chip for anticancer drug sensitivity test. Biomaterials 2005, 26(14):2165-2172.
    • (2005) Biomaterials , vol.26 , Issue.14 , pp. 2165-2172
    • Torisawa, Y.S.1    Shiku, H.2    Yasukawa, T.3    Nishizawa, M.4    Matsue, T.5
  • 104
    • 0026795845 scopus 로고
    • Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer
    • Umbas R., Schalken J.A., Aalders T.W., Carter B.S., Karthaus H.F., Schaafsma H.E., et al. Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. Cancer Research 1992, 52(18):5104-5109.
    • (1992) Cancer Research , vol.52 , Issue.18 , pp. 5104-5109
    • Umbas, R.1    Schalken, J.A.2    Aalders, T.W.3    Carter, B.S.4    Karthaus, H.F.5    Schaafsma, H.E.6
  • 105
    • 84882993448 scopus 로고    scopus 로고
    • Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions
    • Wang Y., Chou B.K., Dowey S., He C., Gerecht S., Cheng L. Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions. Stem Cell Research 2013, 11(3):1103-1116.
    • (2013) Stem Cell Research , vol.11 , Issue.3 , pp. 1103-1116
    • Wang, Y.1    Chou, B.K.2    Dowey, S.3    He, C.4    Gerecht, S.5    Cheng, L.6
  • 106
    • 39749100044 scopus 로고    scopus 로고
    • Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells
    • Wu C.C., Chao Y.C., Chen C.N., Chien S., Chen Y.C., Chien C.C., et al. Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells. Journal of Biomechanics 2008, 41(4):813-821.
    • (2008) Journal of Biomechanics , vol.41 , Issue.4 , pp. 813-821
    • Wu, C.C.1    Chao, Y.C.2    Chen, C.N.3    Chien, S.4    Chen, Y.C.5    Chien, C.C.6
  • 107
    • 77956713213 scopus 로고    scopus 로고
    • Reversion of resistance to cisplatin induced by MG132 in cervical cancer line HCE1 multicellular spheroid
    • Wu Y.L., Yang H.J., Wang K.K., Tao G.S., Liu Y.Z., Hu Y. Reversion of resistance to cisplatin induced by MG132 in cervical cancer line HCE1 multicellular spheroid. Zhonghua fu Chan ke za zhi 2010, 45(4):287-291.
    • (2010) Zhonghua fu Chan ke za zhi , vol.45 , Issue.4 , pp. 287-291
    • Wu, Y.L.1    Yang, H.J.2    Wang, K.K.3    Tao, G.S.4    Liu, Y.Z.5    Hu, Y.6
  • 108
    • 84879463945 scopus 로고    scopus 로고
    • Laminin-111-derived peptide-hyaluronate hydrogels as a synthetic basement membrane
    • Yamada Y., Hozumi K., Katagiri F., Kikkawa Y., Nomizu M. Laminin-111-derived peptide-hyaluronate hydrogels as a synthetic basement membrane. Biomaterials 2013, 34(28):6539-6547.
    • (2013) Biomaterials , vol.34 , Issue.28 , pp. 6539-6547
    • Yamada, Y.1    Hozumi, K.2    Katagiri, F.3    Kikkawa, Y.4    Nomizu, M.5
  • 109
    • 10044265446 scopus 로고    scopus 로고
    • Fabrication of well-defined PLGA scaffolds using novel microembossing and carbon dioxide bonding
    • Yang Y., Basu S., Tomasko D.L., Lee L.J., Yang S.T. Fabrication of well-defined PLGA scaffolds using novel microembossing and carbon dioxide bonding. Biomaterials 2005, 26(15):2585-2594.
    • (2005) Biomaterials , vol.26 , Issue.15 , pp. 2585-2594
    • Yang, Y.1    Basu, S.2    Tomasko, D.L.3    Lee, L.J.4    Yang, S.T.5
  • 110
    • 77958013755 scopus 로고    scopus 로고
    • Derived vascular endothelial cells induced by mucoepidermoid carcinoma cells: 3-Dimensional collagen matrix model
    • Yang S., Guo L.J., Gao Q.H., Xuan M., Tan K., Zhang Q., et al. Derived vascular endothelial cells induced by mucoepidermoid carcinoma cells: 3-Dimensional collagen matrix model. Journal of Zhejiang University. Science. B 2010, 11(10):745-753.
    • (2010) Journal of Zhejiang University. Science. B , vol.11 , Issue.10 , pp. 745-753
    • Yang, S.1    Guo, L.J.2    Gao, Q.H.3    Xuan, M.4    Tan, K.5    Zhang, Q.6
  • 111
    • 79959529448 scopus 로고    scopus 로고
    • A 3D model of ovarian cancer cell lines on peptide nanofiber scaffold to explore the cell-scaffold interaction and chemotherapeutic resistance of anticancer drugs
    • Yang Z., Zhao X. A 3D model of ovarian cancer cell lines on peptide nanofiber scaffold to explore the cell-scaffold interaction and chemotherapeutic resistance of anticancer drugs. International Journal of Nanomedicine 2011, 6:303-310.
    • (2011) International Journal of Nanomedicine , vol.6 , pp. 303-310
    • Yang, Z.1    Zhao, X.2
  • 112
    • 84874000632 scopus 로고    scopus 로고
    • Cancer stem cells niche: A target for novel cancer therapeutics
    • Yi S.Y., Hao Y.B., Nan K.J., Fan T.L. Cancer stem cells niche: A target for novel cancer therapeutics. Cancer Treatment Reviews 2013, 39:290-296.
    • (2013) Cancer Treatment Reviews , vol.39 , pp. 290-296
    • Yi, S.Y.1    Hao, Y.B.2    Nan, K.J.3    Fan, T.L.4
  • 113
    • 0017726744 scopus 로고
    • A simplified method for production and growth of multicellular tumor spheroids
    • Yuhas J.M., Li A.P., Martinez A.O., Ladman A.J. A simplified method for production and growth of multicellular tumor spheroids. Cancer Research 1977, 37(10):3639-3643.
    • (1977) Cancer Research , vol.37 , Issue.10 , pp. 3639-3643
    • Yuhas, J.M.1    Li, A.P.2    Martinez, A.O.3    Ladman, A.J.4
  • 114
    • 79954610473 scopus 로고    scopus 로고
    • Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells
    • Zeng G.F., Cai S.X., Wu G.J. Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells. BMC Cancer 2011, 11:113.
    • (2011) BMC Cancer , vol.11 , pp. 113
    • Zeng, G.F.1    Cai, S.X.2    Wu, G.J.3
  • 116
    • 84901485433 scopus 로고    scopus 로고
    • Cytocompatibility of two porous bioactive glass-ceramic in vitro
    • Zhang Y., Jiang X., Zhang X., Wang D., Zhen L. Cytocompatibility of two porous bioactive glass-ceramic in vitro. West Chin J. Stomatol. 2013, 31(3):294-299.
    • (2013) West Chin J. Stomatol. , vol.31 , Issue.3 , pp. 294-299
    • Zhang, Y.1    Jiang, X.2    Zhang, X.3    Wang, D.4    Zhen, L.5
  • 117
    • 23244447397 scopus 로고    scopus 로고
    • Development of an in vitro multicellular tumor spheroid model using microencapsulation and its application in anticancer drug screening and testing
    • Zhang X., Wang W., Yu W., Xie Y., Zhang X., Zhang Y., et al. Development of an in vitro multicellular tumor spheroid model using microencapsulation and its application in anticancer drug screening and testing. Biotechnology Progress 2005, 21(4):1289-1296.
    • (2005) Biotechnology Progress , vol.21 , Issue.4 , pp. 1289-1296
    • Zhang, X.1    Wang, W.2    Yu, W.3    Xie, Y.4    Zhang, X.5    Zhang, Y.6


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