메뉴 건너뛰기




Volumn 16, Issue 9, 2011, Pages 1119-1124

Semiautomatic growth analysis of multicellular tumor spheroids

Author keywords

3D cell culture; drug response; multicellular tumor spheroids; size measurement; volume growth

Indexed keywords

ARTICLE; AUTOMATION; CANCER GROWTH; CANCER SIZE; COMPUTER PROGRAM; HUMAN; IMAGE ANALYSIS; MICROTITER PLATE ASSAY; MULTICELLULAR TUMOR SPHEROID; PRIORITY JOURNAL; SEDIMENT; TUMOR SPHEROID; TUMOR VOLUME;

EID: 80053532705     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111419501     Document Type: Article
Times cited : (27)

References (21)
  • 1
    • 0024281372 scopus 로고
    • Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model
    • Sutherland R. M. Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model. Science. 1988 ; 240: 177-184
    • (1988) Science , vol.240 , pp. 177-184
    • Sutherland, R.M.1
  • 2
    • 0030697292 scopus 로고    scopus 로고
    • Three-Dimensional Cell Cultures: From Molecular Mechanisms to Clinical Applications
    • Mueller-Klieser W. Three-Dimensional Cell Cultures: From Molecular Mechanisms to Clinical Applications. Am. J. Physiol. 1997 ; 273: C1109 - C1123
    • (1997) Am. J. Physiol , vol.273
    • Mueller-Klieser, W.1
  • 3
    • 0031883574 scopus 로고    scopus 로고
    • Multicellular spheroids: A three-dimensional in vitro culture system to study tumour biology
    • DOI 10.1046/j.1365-2613.1998.00051.x
    • Kunz-Schughart L. A., Kreutz M., Knuechel R. Multicellular Spheroids: A Three-Dimensional in Vitro Culture System to Study Tumour Biology. Int. J. Exp. Pathol. 1998 ; 79: 1-23 (Pubitemid 28137705)
    • (1998) International Journal of Experimental Pathology , vol.79 , Issue.1 , pp. 1-23
    • Kunz-Schughart, L.A.1    Kreutz, M.2    Knuechel, R.3
  • 4
    • 0034328531 scopus 로고    scopus 로고
    • Tumor Biology and Experimental Therapeutics
    • Mueller-Klieser W. Tumor Biology and Experimental Therapeutics. Crit. Rev. Oncol. Hematol. 2000 ; 36: 123-139
    • (2000) Crit. Rev. Oncol. Hematol , vol.36 , pp. 123-139
    • Mueller-Klieser, W.1
  • 5
    • 16544380146 scopus 로고    scopus 로고
    • The Use of 3-D Cultures for High-Throughput Screening: The Multicellular Spheroid Model
    • Kunz-Schughart L. A., Freyer J. P., Hofstaedter F., Ebner R. The Use of 3-D Cultures for High-Throughput Screening: The Multicellular Spheroid Model. J. Biomol. Screen. 2004 ; 9: 273-285
    • (2004) J. Biomol. Screen , vol.9 , pp. 273-285
    • Kunz-Schughart, L.A.1    Freyer, J.P.2    Hofstaedter, F.3    Ebner, R.4
  • 6
    • 36849009670 scopus 로고    scopus 로고
    • Experimental anti-tumor therapy in 3-D: Spheroids - Old hat or new challenge?
    • DOI 10.1080/09553000701727531, PII 787786632
    • Friedrich J., Ebner R., Kunz-Schughart L. A. Experimental Anti-Tumor Therapy in 3-D: Spheroids-Old Hat or New Challenge?. Int. J. Radiat. Biol. 2007 ; 83: 849-871 (Pubitemid 350219104)
    • (2007) International Journal of Radiation Biology , vol.83 , Issue.11-12 , pp. 849-871
    • Friedrich, J.1    Ebner, R.2    Kunz-Schughart, L.A.3
  • 7
    • 60549103259 scopus 로고    scopus 로고
    • Spheroid-Based Drug Screen: Considerations and Practical Approach
    • Friedrich J., Seidel C., Ebner R., Kunz-Schughart L. A. Spheroid-Based Drug Screen: Considerations and Practical Approach. Nat. Protoc. 2009 ; 4: 309-324
    • (2009) Nat. Protoc , vol.4 , pp. 309-324
    • Friedrich, J.1    Seidel, C.2    Ebner, R.3    Kunz-Schughart, L.A.4
  • 8
    • 77958053173 scopus 로고    scopus 로고
    • Efficacy of Catumaxomab in Tumor Spheroid Killing Is Mediated by Its Trifunctional Mode of Action
    • Hirschhaeuser F., Walenta S., Mueller-Klieser W. Efficacy of Catumaxomab in Tumor Spheroid Killing Is Mediated by Its Trifunctional Mode of Action. Cancer Immunol. Immunother. 2010 ; 59: 1675-1684
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 1675-1684
    • Hirschhaeuser, F.1    Walenta, S.2    Mueller-Klieser, W.3
  • 11
    • 0021361689 scopus 로고
    • Development of multicellular spheroids of HeLa cells cocultured with fibroblasts and their responses to X-irradiation
    • Sasaki T., Yamamoto M., Yamaguchi T., Sugiyama S. Development of Multicellular Spheroids of HeLa Cells Cocultured with Fibroblasts and Their Response to X-Irradiation. Cancer Res. 1984 ; 44: 345-351 (Pubitemid 14177761)
    • (1984) Cancer Research , vol.44 , Issue.1 , pp. 345-351
    • Sasaki, T.1    Yamamoto, M.2    Yamaguchi, T.3    Sugiyama, S.4
  • 12
    • 0022642722 scopus 로고
    • Regulation of growth saturation and development of necrosis in EMT6/Ro multicellular spheroids by the glucose and oxygen supply
    • Freyer J. P., Sutherland R. M. Regulation of Growth Saturation and Development of Necrosis in EMT6/Ro Multicellular Spheroids by the Glucose and Oxygen Supply. Cancer Res. 1986 ; 46: 3504-3512 (Pubitemid 16096899)
    • (1986) Cancer Research , vol.46 , Issue.7 , pp. 3504-3512
    • Freyer, J.P.1    Sutherland, R.M.2
  • 14
    • 33751572020 scopus 로고    scopus 로고
    • Rapid generation of single-tumor spheroids for high-throughput cell function and toxicity analysis
    • DOI 10.1177/1087057106292763
    • Ivascu A., Kubbies M. Rapid Generation of Single-Tumor Spheroids for High-Throughput Cell Function and Toxicity Analysis. J. Biomol. Screen. 2006 ; 11: 922-932 (Pubitemid 44847146)
    • (2006) Journal of Biomolecular Screening , vol.11 , Issue.8 , pp. 922-932
    • Ivascu, A.1    Kubbies, M.2
  • 16
    • 33644861956 scopus 로고    scopus 로고
    • A 50 Hz Sinusoidal Magnetic Field Does Not Damage MG-63 Three-Dimensional Tumor Spheroids but Induces Changes in Their Invasive Properties
    • Santini M. T., Rainaldi G., Ferrante A., Indovina P., Donelli G., Indovina P. L. A 50 Hz Sinusoidal Magnetic Field Does Not Damage MG-63 Three-Dimensional Tumor Spheroids but Induces Changes in Their Invasive Properties. Bioelectromagnetics. 2006 ; 27: 132-141
    • (2006) Bioelectromagnetics , vol.27 , pp. 132-141
    • Santini, M.T.1    Rainaldi, G.2    Ferrante, A.3    Indovina, P.4    Donelli, G.5    Indovina, P.L.6
  • 17
    • 0023378074 scopus 로고
    • Viable Sorting of Intact Multicellular Spheroids by Flow Cytometry
    • Freyer J. P., Wilder M. E., Jett J. H. Viable Sorting of Intact Multicellular Spheroids by Flow Cytometry. Cytometry. 1987 ; 8: 427-436
    • (1987) Cytometry , vol.8 , pp. 427-436
    • Freyer, J.P.1    Wilder, M.E.2    Jett, J.H.3
  • 18
    • 0024351284 scopus 로고
    • Use of xantham gum to suspend large particles during flow cytometric analysis and sorting
    • DOI 10.1002/cyto.990100620
    • Freyer J. P., Fillak D., Jett J. H. Use of Xantham Gum to Suspend Large Particles during Flow Cytometric Analysis and Sorting. Cytometry. 1989 ; 10: 803-806 (Pubitemid 20004743)
    • (1989) Cytometry , vol.10 , Issue.6 , pp. 803-806
    • Freyer, J.P.1    Fillak, D.2    Jett, J.H.3
  • 19
    • 84857106351 scopus 로고    scopus 로고
    • Multicellular Cytometric Analyses and Sorting on Embryoid Bodies and Embryonic Stem Cell Clusters
    • June 23-25 [last update August 6, 2010]
    • HungT.BaranA.WareC.PulakR.Multicellular Cytometric Analyses and Sorting on Embryoid Bodies and Embryonic Stem Cell Clusters. 3rd Annual ISSCR Meeting2005, June 23-25 [last update August 6, 2010]. http://www.unionbio.com/ documents/ISSCR05PosterHandout.pdf.
    • 3rd Annual ISSCR Meeting2005
    • Hung, T.1    Baran, A.2    Ware, C.3    Pulak, R.4
  • 20
    • 0035014916 scopus 로고    scopus 로고
    • A multicellular spheroid-based sensor for anti-cancer therapeutics
    • DOI 10.1016/S0956-5663(01)00140-3, PII S0956566301001403
    • Thielecke H., Mack A., Robitzki A. A Multicellular Spheroid-Based Sensor for Anti-Cancer Therapeutics. Biosens. Bioelectron. 2001 ; 16: 261-269 (Pubitemid 32522785)
    • (2001) Biosensors and Bioelectronics , vol.16 , Issue.4-5 , pp. 261-269
    • Thielecke, H.1    Mack, A.2    Robitzki, A.3
  • 21
    • 84857102915 scopus 로고    scopus 로고
    • World Intellectual Property Organization, CH-1211 Geneva 20, Switzerland [last update August 6, 2010]
    • ThieleckeH.RobitzkiA.Device and Method for Characterizing Spheroids. World Intellectual Property Organization, CH-1211 Geneva 20, Switzerland [last update August 6, 2010]. http://www.wipo.int/pctdb/en/wo.jsp?wo=2001023865.
    • Device and Method for Characterizing Spheroids
    • Thielecke, H.1    Robitzki, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.