A more aggressive breast cancer spheroid model coupled to an electronic capillary sensor system for a high-content screening of cytotoxic agents in cancer therapy: 3-Dimensional in vitro tumor spheroids as a screening model

Journal of Biomolecular Screening

Volumn 10, Issue 7, 2005, Pages 705-714

  Bartholoma P ^a   Empidjati, ^a   Reininger Mack, A ^a   Zhang, Zhihong ^a   Thielecke, H ^a   Robitzki, A ^b  

^a FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Anticancer therapy; Breast cancer; Impedance spectroscopy; In vitro tumor screening model; Real time monitoring; Tumor spheroids

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; CYTOTOXIC AGENT; METHOTREXATE; PROTEIN BCL XL; TELOMERASE;

APOPTOSIS; ARTICLE; BIOSENSOR; BREAST CANCER; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL DEATH; CELL IMMORTALIZATION; CONCENTRATION RESPONSE; ELECTRONIC SENSOR; EVALUATION; EXPRESSION VECTOR; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMPEDANCE SPECTROSCOPY; PRIORITY JOURNAL; PROCESS MONITORING; PROTEIN EXPRESSION; SPECTROSCOPY; SPHEROID CELL; TELOMERE; TIME; TUMOR MODEL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-X PROTEIN; BREAST NEOPLASMS; CASPASE 3; CELL LINE, TUMOR; FEMALE; HUMANS; METHOTREXATE; MODELS, BIOLOGICAL; SPHEROIDS, CELLULAR;

EID: 26944481910     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057105277841     Document Type: Article

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