Three-dimensional porous silk tumor constructs in the approximation of in vivo osteosarcoma physiology

Biomaterials

Volumn 32, Issue 26, 2011, Pages 6131-6137

  Tan, Pamela H S ^a   Aung, K Z ^a   Toh, S L ^a   Goh, James C H ^a   Nathan, S S ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Angiogenesis; Cell culture; Cell signalling; Scaffold; Silk

Indexed keywords

ANGIOGENESIS; ANGIOGENIC FACTOR; ANGIOGENIC GROWTH FACTORS; ANIMAL MODEL; ANTICANCER DRUG DISCOVERY; CELL SIGNALLING; CULTURE SYSTEMS; DRUG EFFICACY; DRUG TESTING; EXPRESSION PROFILE; FREEZE DRYING; GENE EXPRESSION PROFILES; GROWTH OF CELLS; HIGH THROUGHPUT; IMMUNOHISTOCHEMISTRY; IN-VITRO; IN-VIVO; OSTEOSARCOMA; OSTEOSARCOMA CELLS; REAL-TIME POLYMERASE CHAIN REACTION; SILK SCAFFOLD; TARGETED CHEMOTHERAPY; THREE DIMENSIONAL (3D) GROWTH; TUMOR MODELS; TUMORIGENESIS;

ANIMAL CELL CULTURE; CELL GROWTH; CELLS; CHEMOTHERAPY; DRUG PRODUCTS; GENE EXPRESSION; MAMMALS; MOLECULAR BIOLOGY; POLYMERASE CHAIN REACTION; SCAFFOLDS (BIOLOGY); SILK; TUMORS;

THREE DIMENSIONAL;

ANGIOGENIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR; CYCLIN B1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 8; KI 67 ANTIGEN; SILK FIBROIN; TRANSCRIPTION FACTOR E2F1; TUMOR MARKER; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FREEZE DRYING; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; LARGE SCALE PRODUCTION; MOLECULAR BIOLOGY; MOUSE; NANOFABRICATION; NONHUMAN; OSTEOSARCOMA; OSTEOSARCOMA CELL; PATHOPHYSIOLOGY; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SILK; SILK TUMOR CONSTRUCT; STAINING; THREE DIMENSIONAL IMAGING; TUMOR MICROENVIRONMENT; TUMOR SEEDING;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; FIBROBLAST GROWTH FACTOR 2; HYDROGEN-ION CONCENTRATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-8; MICE; MICE, SCID; MICROSCOPY, PHASE-CONTRAST; OSTEOSARCOMA; OXYGEN; SILK; TISSUE SCAFFOLDS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA;

EID: 79959884148     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.04.084     Document Type: Article

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