메뉴 건너뛰기




Volumn 34, Issue 37, 2013, Pages 9462-9474

A silk fibroin based hepatocarcinoma model and the assessment of the drug response in hyaluronan-binding protein 1 overexpressed HepG2 cells

Author keywords

4 Methylumbelliferone; Drug screening; Hyaluronan binding protein 1; Scaffold; Silk fibroin

Indexed keywords

4-METHYLUMBELLIFERONE; CELLULAR MORPHOLOGY; DRUG SCREENING; EXTRACELLULAR MATRICES; HYALURONAN-BINDING PROTEINS; MULTICELLULAR AGGREGATES; SILK FIBROIN; THERAPEUTIC INTERVENTION;

EID: 84884813681     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.08.047     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 80054972160 scopus 로고    scopus 로고
    • 3D tumour models: novel invitro approaches to cancer studies
    • Nyga A., Cheema U., Loizidou M. 3D tumour models: novel invitro approaches to cancer studies. JCell Commun Signal 2011, 5:239-248.
    • (2011) JCell Commun Signal , vol.5 , pp. 239-248
    • Nyga, A.1    Cheema, U.2    Loizidou, M.3
  • 2
    • 34247857741 scopus 로고    scopus 로고
    • Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment. Possible involvement of versican/PG-M
    • Koyama H., Hibi T., Isogai Z., Yoneda M., Fujimori M., Amano J., et al. Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment. Possible involvement of versican/PG-M. Am J Pathol 2007, 170:1086-1099.
    • (2007) Am J Pathol , vol.170 , pp. 1086-1099
    • Koyama, H.1    Hibi, T.2    Isogai, Z.3    Yoneda, M.4    Fujimori, M.5    Amano, J.6
  • 3
    • 0037085376 scopus 로고    scopus 로고
    • Hyaluronan-cell interactions in cancer and vascular disease
    • Toole B.P., Wight T.N., Tammi M. Hyaluronan-cell interactions in cancer and vascular disease. JBiol Chem 2002, 277:4593-4596.
    • (2002) JBiol Chem , vol.277 , pp. 4593-4596
    • Toole, B.P.1    Wight, T.N.2    Tammi, M.3
  • 4
    • 0036731866 scopus 로고    scopus 로고
    • Hyaluronan and tumor growth
    • Toole B.P., Hascall V.C. Hyaluronan and tumor growth. Am J Pathol 2002, 161:745-747.
    • (2002) Am J Pathol , vol.161 , pp. 745-747
    • Toole, B.P.1    Hascall, V.C.2
  • 5
    • 23444445895 scopus 로고    scopus 로고
    • Hyaluronan metabolism: a major paradox in cancer biology
    • Stern R. Hyaluronan metabolism: a major paradox in cancer biology. Pathol Biol 2005, 53:372-382.
    • (2005) Pathol Biol , vol.53 , pp. 372-382
    • Stern, R.1
  • 6
    • 9444254661 scopus 로고    scopus 로고
    • Differential expression of hyaluronic acid binding protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma
    • Ghosh I., Chowdhury A.R., Rajeswari M.R., Datta K. Differential expression of hyaluronic acid binding protein 1 (HABP1)/P32/C1QBP during progression of epidermal carcinoma. Mol Cell Biochem 2004, 267:133-139.
    • (2004) Mol Cell Biochem , vol.267 , pp. 133-139
    • Ghosh, I.1    Chowdhury, A.R.2    Rajeswari, M.R.3    Datta, K.4
  • 7
    • 2942514464 scopus 로고    scopus 로고
    • Receptor for the globular heads of C1q (gC1q-R, p33, hyaluronan-binding protein) is preferentially expressed by adenocarcinoma cells
    • Rubinstein D.B., Stortchevoi A., Boosalis M., Ashfaq R., Ghebrehiwet B., Peerschke E.I., et al. Receptor for the globular heads of C1q (gC1q-R, p33, hyaluronan-binding protein) is preferentially expressed by adenocarcinoma cells. Int J Cancer 2004, 110:741-750.
    • (2004) Int J Cancer , vol.110 , pp. 741-750
    • Rubinstein, D.B.1    Stortchevoi, A.2    Boosalis, M.3    Ashfaq, R.4    Ghebrehiwet, B.5    Peerschke, E.I.6
  • 8
    • 79960703236 scopus 로고    scopus 로고
    • Hyaluronan-binding protein (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin α(v)β(3) interaction
    • Prakash M., Kale S., Ghosh I., Kundu G.C., Datta K. Hyaluronan-binding protein (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin α(v)β(3) interaction. Cell Signal 2011, 23:1563-1577.
    • (2011) Cell Signal , vol.23 , pp. 1563-1577
    • Prakash, M.1    Kale, S.2    Ghosh, I.3    Kundu, G.C.4    Datta, K.5
  • 9
    • 52049123781 scopus 로고    scopus 로고
    • Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma
    • Fogal V., Zhang L., Krajewski S., Rouslahti E. Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma. Cancer Res 2008, 68:7210-7218.
    • (2008) Cancer Res , vol.68 , pp. 7210-7218
    • Fogal, V.1    Zhang, L.2    Krajewski, S.3    Rouslahti, E.4
  • 10
    • 77749334738 scopus 로고    scopus 로고
    • Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation
    • Fogal V., Richardson A.D., Karmali P.P., Scheffler I.E., Smith J.W., Ruoslahti E. Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell Biol 2010, 30:1303-1318.
    • (2010) Mol Cell Biol , vol.30 , pp. 1303-1318
    • Fogal, V.1    Richardson, A.D.2    Karmali, P.P.3    Scheffler, I.E.4    Smith, J.W.5    Ruoslahti, E.6
  • 11
    • 70349238709 scopus 로고    scopus 로고
    • Increased expression of hyaluronic acid binding protein 1 is correlated with poor prognosis in patients with breast cancer
    • Chen Y.B., Jiang C.T., Zhang G.Q., Wang J.S., Pang D.A. Increased expression of hyaluronic acid binding protein 1 is correlated with poor prognosis in patients with breast cancer. JSurg Oncol 2009, 100:382-386.
    • (2009) JSurg Oncol , vol.100 , pp. 382-386
    • Chen, Y.B.1    Jiang, C.T.2    Zhang, G.Q.3    Wang, J.S.4    Pang, D.A.5
  • 12
    • 38349035719 scopus 로고    scopus 로고
    • Excessive reactive oxygen species induces apoptosis in fibroblasts: role of mitochondrially accumulated hyaluronic acid binding protein 1 (HABP1/p32/gC1qR)
    • Chowdhury A.R., Ghosh I., Datta K. Excessive reactive oxygen species induces apoptosis in fibroblasts: role of mitochondrially accumulated hyaluronic acid binding protein 1 (HABP1/p32/gC1qR). Exp Cell Res 2008, 314:651-667.
    • (2008) Exp Cell Res , vol.314 , pp. 651-667
    • Chowdhury, A.R.1    Ghosh, I.2    Datta, K.3
  • 13
    • 0035227318 scopus 로고    scopus 로고
    • Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration
    • Huang Z.Z., Chen C., Zeng Z., Yang H., Oh J., Chen L., et al. Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration. FASEB 2001, 15:19-21.
    • (2001) FASEB , vol.15 , pp. 19-21
    • Huang, Z.Z.1    Chen, C.2    Zeng, Z.3    Yang, H.4    Oh, J.5    Chen, L.6
  • 14
    • 0036306930 scopus 로고    scopus 로고
    • Effects of epigallocatechin 3-O-gallate on cellular antioxidative system in HepG2 cells
    • Murakami C., Hirakawa Y., Inui H., Nakano Y., Yoshida H. Effects of epigallocatechin 3-O-gallate on cellular antioxidative system in HepG2 cells. JNutr Sci Vitaminol 2002, 48:89-94.
    • (2002) JNutr Sci Vitaminol , vol.48 , pp. 89-94
    • Murakami, C.1    Hirakawa, Y.2    Inui, H.3    Nakano, Y.4    Yoshida, H.5
  • 15
    • 84861740638 scopus 로고    scopus 로고
    • Overexpression of hyaluronan-binding protein 1 (HABP1/p32/gC1qR) in HepG2 cells leads to increased hyaluronan synthesis and cell proliferation by up-regulation of cyclin D1 in AKT-dependent pathway
    • Kaul R., Saha P., Saradhi M., Prasad R.L., Chatterjee S., Ghosh I., et al. Overexpression of hyaluronan-binding protein 1 (HABP1/p32/gC1qR) in HepG2 cells leads to increased hyaluronan synthesis and cell proliferation by up-regulation of cyclin D1 in AKT-dependent pathway. JBiol Chem 2012, 287:19750-19764.
    • (2012) JBiol Chem , vol.287 , pp. 19750-19764
    • Kaul, R.1    Saha, P.2    Saradhi, M.3    Prasad, R.L.4    Chatterjee, S.5    Ghosh, I.6
  • 16
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • Cukierman E., Pankov R., Stevens D.R., Yamada K.M. Taking cell-matrix adhesions to the third dimension. Science 2001, 294:1708-1712.
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3    Yamada, K.M.4
  • 17
    • 0029895788 scopus 로고    scopus 로고
    • Review association of TM4SF proteins with integrins: relevance to cancer
    • Hemler M.E., Mannion B.A., Berditchevski F. Review association of TM4SF proteins with integrins: relevance to cancer. Biochim Biophys Acta 1996, 1287:67-71.
    • (1996) Biochim Biophys Acta , vol.1287 , pp. 67-71
    • Hemler, M.E.1    Mannion, B.A.2    Berditchevski, F.3
  • 18
    • 0030272735 scopus 로고    scopus 로고
    • Integrin cytoplasmic interactions and bidirectional transmembrane signalling
    • Dedhar S., Hannigan G.E. Integrin cytoplasmic interactions and bidirectional transmembrane signalling. Curr Opin Cell Biol 1996, 8:657-669.
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 657-669
    • Dedhar, S.1    Hannigan, G.E.2
  • 20
    • 73949157882 scopus 로고    scopus 로고
    • Network-based drugs and biomarkers
    • Erler J.T., Linding R. Network-based drugs and biomarkers. JPathol 2010, 220:290-296.
    • (2010) JPathol , vol.220 , pp. 290-296
    • Erler, J.T.1    Linding, R.2
  • 21
    • 80054011623 scopus 로고    scopus 로고
    • MEMS micro well and micro column arrays: novel methods for high-throughput cell-based assays
    • Chen P.C., Huang Y.Y., Juang J.L. MEMS micro well and micro column arrays: novel methods for high-throughput cell-based assays. Lab Chip 2011, 11:3619-3625.
    • (2011) Lab Chip , vol.11 , pp. 3619-3625
    • Chen, P.C.1    Huang, Y.Y.2    Juang, J.L.3
  • 23
    • 0035035529 scopus 로고    scopus 로고
    • Differential expression of the fibroin gene in developmental stages of silkworm, Antheraea mylitta (Saturniidae)
    • Datta A., Ghosh A.K., Kundu S.C. Differential expression of the fibroin gene in developmental stages of silkworm, Antheraea mylitta (Saturniidae). Comp Biochem Physiol B 2001, 129:197-204.
    • (2001) Comp Biochem Physiol B , vol.129 , pp. 197-204
    • Datta, A.1    Ghosh, A.K.2    Kundu, S.C.3
  • 27
    • 84865022909 scopus 로고    scopus 로고
    • Silk sericin/polyacrylamide in situ forming hydrogels for dermal reconstruction
    • Kundu B., Kundu S.C. Silk sericin/polyacrylamide in situ forming hydrogels for dermal reconstruction. Biomaterials 2012, 33:7456-7467.
    • (2012) Biomaterials , vol.33 , pp. 7456-7467
    • Kundu, B.1    Kundu, S.C.2
  • 28
    • 44649128641 scopus 로고    scopus 로고
    • Cartilage tissue engineering: directed differentiation of embryonic stem cells in three-dimensional hydrogel culture
    • Hwang N.S., Varghese S., Elisseeff J.H. Cartilage tissue engineering: directed differentiation of embryonic stem cells in three-dimensional hydrogel culture. Methods Mol Biol 2007, 407:351-373.
    • (2007) Methods Mol Biol , vol.407 , pp. 351-373
    • Hwang, N.S.1    Varghese, S.2    Elisseeff, J.H.3
  • 29
    • 0344718455 scopus 로고    scopus 로고
    • Engineering bone regeneration with bio-absorbable scaffolds with novel microarchitecture
    • Whang K., Healy K.E., Elenz D.R., Nam E.K., Tsai D.C., Thomas C.H., et al. Engineering bone regeneration with bio-absorbable scaffolds with novel microarchitecture. Tissue Eng 1999, 5:35-51.
    • (1999) Tissue Eng , vol.5 , pp. 35-51
    • Whang, K.1    Healy, K.E.2    Elenz, D.R.3    Nam, E.K.4    Tsai, D.C.5    Thomas, C.H.6
  • 30
    • 0037184909 scopus 로고    scopus 로고
    • Taking the study of cancer cell survival to a new dimension
    • Jacks T., Weinberg R.A. Taking the study of cancer cell survival to a new dimension. Cell 2002, 111:923-925.
    • (2002) Cell , vol.111 , pp. 923-925
    • Jacks, T.1    Weinberg, R.A.2
  • 31
    • 0036948067 scopus 로고    scopus 로고
    • Apoptotic volume decrease and the incredible shrinking cell
    • Bortner C.D., Cidlowski J.A. Apoptotic volume decrease and the incredible shrinking cell. Cell Death Differ 2002, 9:1307-1310.
    • (2002) Cell Death Differ , vol.9 , pp. 1307-1310
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 32
    • 50149105712 scopus 로고    scopus 로고
    • Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression
    • Itano N., Zhuo L., Kimata K. Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression. Cancer Sci 2008, 99:1720-1725.
    • (2008) Cancer Sci , vol.99 , pp. 1720-1725
    • Itano, N.1    Zhuo, L.2    Kimata, K.3
  • 33
    • 0028901654 scopus 로고
    • Hyaluronic-acid-deficient extracellular matrix induced by addition of 4- methylumbelliferone to the medium of cultured human skin fibroblasts
    • Nakamura T., Takagaki K., Shibata S., Tanaka K., Higuchi T., Endo M. Hyaluronic-acid-deficient extracellular matrix induced by addition of 4- methylumbelliferone to the medium of cultured human skin fibroblasts. Biochem Biophys Res Commun 1995, 208:470-475.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 470-475
    • Nakamura, T.1    Takagaki, K.2    Shibata, S.3    Tanaka, K.4    Higuchi, T.5    Endo, M.6
  • 34
    • 33744510813 scopus 로고    scopus 로고
    • Study of hyaluronan synthase inhibitor, 4- methylumbelliferone derivatives on human pancreatic cancer cell (KP1-NL)
    • Morohashi H., Kon A., Nakai M., Yamaguchi M., Kakizaki I., Yoshihara S., et al. Study of hyaluronan synthase inhibitor, 4- methylumbelliferone derivatives on human pancreatic cancer cell (KP1-NL). Biochem Biophys Res Commun 2006, 345:1454-1459.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 1454-1459
    • Morohashi, H.1    Kon, A.2    Nakai, M.3    Yamaguchi, M.4    Kakizaki, I.5    Yoshihara, S.6
  • 35
    • 38149132242 scopus 로고    scopus 로고
    • Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma
    • Wu T.T., Hsieh Y.H., Hsieh Y.S., Liu J.Y. Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma. Cell Biochem 2008, 103:9-20.
    • (2008) Cell Biochem , vol.103 , pp. 9-20
    • Wu, T.T.1    Hsieh, Y.H.2    Hsieh, Y.S.3    Liu, J.Y.4
  • 36
    • 0025038449 scopus 로고
    • Hyaluronan and its binding proteins, the hyaladherins
    • Toole B.P. Hyaluronan and its binding proteins, the hyaladherins. Curr Opin Cell Biol 1990, 2:839-844.
    • (1990) Curr Opin Cell Biol , vol.2 , pp. 839-844
    • Toole, B.P.1
  • 37
    • 44749083565 scopus 로고    scopus 로고
    • Association between cancer and "acid mucopolysaccharides": an old concept comes of age finally
    • Stern R. Association between cancer and "acid mucopolysaccharides": an old concept comes of age finally. Semin Cancer Biol 2008, 18:238-243.
    • (2008) Semin Cancer Biol , vol.18 , pp. 238-243
    • Stern, R.1
  • 39
    • 0036924902 scopus 로고    scopus 로고
    • Improving the next generation of bioartificial liver devices
    • Allen J.W., Bhatia S.N. Improving the next generation of bioartificial liver devices. Semin Cell Dev Biol 2002, 13:447-454.
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 447-454
    • Allen, J.W.1    Bhatia, S.N.2
  • 40
    • 0027692817 scopus 로고
    • Growth versus function in the three-dimensional culture of single and aggregated hepatocytes within collagen gels
    • Parsons-Wingerter P.A., Saltzman W.M. Growth versus function in the three-dimensional culture of single and aggregated hepatocytes within collagen gels. Biotechnol Prog 1993, 9:600-607.
    • (1993) Biotechnol Prog , vol.9 , pp. 600-607
    • Parsons-Wingerter, P.A.1    Saltzman, W.M.2
  • 41
    • 0033106004 scopus 로고    scopus 로고
    • Overproduction of hyaluronan by expression of the hyaluronan synthase Has2 enhances anchorage-independent growth and tumorigenicity
    • Kosaki R., Watanabe K., Yamaguchi Y. Overproduction of hyaluronan by expression of the hyaluronan synthase Has2 enhances anchorage-independent growth and tumorigenicity. Cancer Res 1999, 59:1141-1145.
    • (1999) Cancer Res , vol.59 , pp. 1141-1145
    • Kosaki, R.1    Watanabe, K.2    Yamaguchi, Y.3
  • 42
    • 0037085254 scopus 로고    scopus 로고
    • Signaling properties of hyaluronan receptors
    • Turley E.A., Noble P.W., Bourguignon L.Y. Signaling properties of hyaluronan receptors. JBiol Chem 2002, 277:4589-4592.
    • (2002) JBiol Chem , vol.277 , pp. 4589-4592
    • Turley, E.A.1    Noble, P.W.2    Bourguignon, L.Y.3
  • 43
    • 67349260101 scopus 로고    scopus 로고
    • 4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3
    • Kultti A., Pasonen-Seppänen S., Jauhiainen M., Rilla K.J., Kärnä R., Pyöriä E., et al. 4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3. Exp Cell Res 2009, 315:1914-1923.
    • (2009) Exp Cell Res , vol.315 , pp. 1914-1923
    • Kultti, A.1    Pasonen-Seppänen, S.2    Jauhiainen, M.3    Rilla, K.J.4    Kärnä, R.5    Pyöriä, E.6
  • 44
    • 33644797914 scopus 로고    scopus 로고
    • 4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells
    • Nakazawa H., Yoshihara S., Kudo D., Morohashi H., Kakizaki I., Kon A., et al. 4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells. Cancer Chemother Pharmacol 2006, 57:165-170.
    • (2006) Cancer Chemother Pharmacol , vol.57 , pp. 165-170
    • Nakazawa, H.1    Yoshihara, S.2    Kudo, D.3    Morohashi, H.4    Kakizaki, I.5    Kon, A.6
  • 45
  • 46
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion
    • Yamaguchi H., Condeelis J. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta 2007, 1773:642-652.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 48
    • 78049452610 scopus 로고    scopus 로고
    • Delivering nanomedicine to solid tumors
    • Jain R.K., Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat Rev Clin Oncol 2010, 7:653-664.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 653-664
    • Jain, R.K.1    Stylianopoulos, T.2
  • 49
    • 44749087178 scopus 로고    scopus 로고
    • Altered hyaluronan biosynthesis in cancer progression
    • Itano N., Kimata K. Altered hyaluronan biosynthesis in cancer progression. Semin Cancer Biol 2008, 18:268-274.
    • (2008) Semin Cancer Biol , vol.18 , pp. 268-274
    • Itano, N.1    Kimata, K.2
  • 50
    • 0028670129 scopus 로고
    • Regulation of protein kinase C and role in cancer biology
    • Blobe G.C., Obeid L.M., Hannun Y.A. Regulation of protein kinase C and role in cancer biology. Cancer Metastasis Rev 1994, 13:411-431.
    • (1994) Cancer Metastasis Rev , vol.13 , pp. 411-431
    • Blobe, G.C.1    Obeid, L.M.2    Hannun, Y.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.