Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association with inhibiting spinal JAK2/STAT3 signaling in neuropathic pain in rats

Neuroscience

Volumn 273, Issue , 2014, Pages 65-78

  Wang, Z F ^a,b   Li, Q ^a   Liu, S B ^a   Mi, W L ^a   Hu, S ^a   Zhao, J ^a   Tian, Y ^a   Mao Ying, Q L ^a   Jiang, J W ^a   Ma, H J ^a   Wang, Y Q ^a   Wu, G C ^a  

^a FUDAN UNIVERSITY   (China)

^b FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Inflammation; JAK2 STAT3; Neuropathic pain; Spinal cord

Indexed keywords

4 [[(4 METHYLPHENYL)SULFONYLOXY]ACETAMIDO]SALICYLIC ACID; ACETYLSALICYLIC ACID; ASPIRIN TRIGGERED LIPOXIN A4; BUTOXY CARBONYLPHENYLALANYLLEUCYLPHENYLALANYLLEUCYLPHENYLALANINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; JANUS KINASE 2; LIPOXIN A; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; IL1B PROTEIN, RAT; JAK2 PROTEIN, RAT; LIPOXIN; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; SOCS3 PROTEIN, RAT; STAT3 PROTEIN, RAT; SUPPRESSOR OF CYTOKINE SIGNALING;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; CHRONIC CONSTRICTION INJURY; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MECHANICAL ALLODYNIA; NERVOUS SYSTEM INFLAMMATION; NEUROPATHIC PAIN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; DRUG EFFECTS; HYPERALGESIA; IMMUNOMODULATION; METABOLISM; NEURALGIA; PATHOPHYSIOLOGY; PHYSIOLOGY; SCIATIC NERVE; SPINAL CORD; SPRAGUE DAWLEY RAT; STENOSIS, OCCLUSION AND OBSTRUCTION; TOUCH;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; ASTROCYTES; CONSTRICTION, PATHOLOGIC; DISEASE MODELS, ANIMAL; HYPERALGESIA; INTERLEUKIN-1BETA; INTERLEUKIN-6; JANUS KINASE 2; LIPOXINS; MALE; NEURALGIA; NEUROIMMUNOMODULATION; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINAL CORD; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TOUCH; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84901493330     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.04.052     Document Type: Article

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