SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury

Journal of Neuroscience

Volumn 30, Issue 16, 2010, Pages 5754-5766

  Dominguez, Elisa ^a,b   Mauborgne, Annie ^a,b   Mallet, Jacques ^a,b   Desclaux, Mathieu ^a,b   Pohl, Michel ^a,b  

^a INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; INTERLEUKIN 6; JANUS KINASE 2; LENTIVIRUS VECTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ALLODYNIA; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; IMMUNOHISTOCHEMISTRY; MALE; MECHANICAL ALLODYNIA; MICROGLIA; MYELITIS; NERVE CELL PLASTICITY; NERVE INJURY; NONHUMAN; PERIPHERAL NERVE INJURY; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINE; SPRAGUE DAWLEY RAT;

ANIMALS; CELL LINE; CELLS, CULTURED; HUMANS; INFLAMMATION MEDIATORS; JANUS KINASES; MARMOTA; PAIN; PAIN MEASUREMENT; PHYSICAL STIMULATION; RATS; SCIATIC NEUROPATHY; SIGNAL TRANSDUCTION; SPINAL CORD; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 77951533730     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5007-09.2010     Document Type: Article

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