Lipoxin A 4 inhibits 5-lipoxygenase translocation and leukotrienes biosynthesis to exert a neuroprotective effect in cerebral ischemia/reperfusion injury

Journal of Molecular Neuroscience

Volumn 48, Issue 1, 2012, Pages 185-200

  Wu, Le ^a,b   Miao, Sen ^a   Zou, Lin Bing ^a   Wu, Ping ^a   Hao, Hua ^a   Tang, Ke ^a   Zeng, Pan ^a   Xiong, Jing ^a   Li, Hong Hua ^b   Wu, Qiang ^b   Cai, Lei ^a   Ye, Du Yun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

Author keywords

5 Lipoxygenase; Ischemia reperfusion; Leukotriene; Lipoxin A 4

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; LEUKOTRIENE; LEUKOTRIENE B4; LEUKOTRIENE C4; LIPOXIN A; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ENZYME INHIBITOR; FLAVONOID; GLUCOSE; LIPOXIN; MESSENGER RNA; NEUROPROTECTIVE AGENT; OXYGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BIOSYNTHESIS; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; DRUG EFFECT; GENE TRANSLOCATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION; ANIMAL; CYTOLOGY; DISEASE MODEL; GENETICS; METABOLISM; PATHOLOGY; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; ARACHIDONATE 5-LIPOXYGENASE; ASTROCYTES; BRAIN EDEMA; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FLAVONOIDS; GLUCOSE; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENES; LIPOXINS; MALE; MAP KINASE SIGNALING SYSTEM; NEUROPROTECTIVE AGENTS; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RNA, MESSENGER;

EID: 84865137948     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9807-4     Document Type: Article

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