Spinal injection of docosahexaenoic acid attenuates carrageenan-induced inflammatory pain through inhibition of microglia-mediated neuroinflammation in the spinal cord

Neuroscience

Volumn 241, Issue , 2013, Pages 22-31

  Lu, Y ^a   Zhao, L X ^a   Cao, D L ^a   Gao, Y J ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Carrageenan; Chemokines; Cytokines; Docosahexaenoic acid; Inflammatory pain; Microglia

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CARRAGEENAN; CHEMOKINE; CYTOKINE; DOCOSAHEXAENOIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN CCL10; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HYPERALGESIA; HYPERSENSITIVITY; INFLAMMATORY PAIN; MALE; MICROGLIA; MOUSE; NERVE CELL CULTURE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SPINAL CORD;

ANIMALS; BLOTTING, WESTERN; CARRAGEENAN; DOCOSAHEXAENOIC ACIDS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INJECTIONS, SPINAL; MALE; MICE; MICE, INBRED ICR; MICROGLIA; PAIN; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84876312609     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.03.003     Document Type: Article

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