Lipoxin A 4 analog attenuates morphine antinociceptive tolerance, withdrawal-induced hyperalgesia, and glial reaction and cytokine expression in the spinal cord of rat

Neuroscience

Volumn 208, Issue , 2012, Pages 1-10

  Jin, H ^a   Li, Y H ^a   Xu, J S ^a   Guo, G Q ^a   Chen, D L ^a   Bo, Y ^a  

^a FIRST PEOPLE S HOSPITAL OF YUNNAN PROVINCE   (China)

Author keywords

Inflammation; Lipoxin A 4; Morphine; Tolerance

Indexed keywords

5,6 LIPOXIN A4 METHYL ESTER; ANALGESIC AGENT; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MORPHINE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; LIPOXIN; LIPOXIN A; LIPOXIN A4 METHYL ESTER; NARCOTIC ANALGESIC AGENT;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG TOLERANCE; GLIA CELL; HEAT STRESS; HYPERALGESIA; LUMBAR SPINAL CORD; MALE; MECHANICAL STRESS; MICROGLIA; MORNING DOSAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; RAT; TAIL FLICK TEST; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GLIA; INTRASPINAL DRUG ADMINISTRATION; MACROPHAGE ACTIVATION; METABOLISM; PAIN ASSESSMENT; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD; SPRAGUE DAWLEY RAT; WESTERN BLOTTING; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CYTOKINES; DRUG TOLERANCE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; INJECTIONS, SPINAL; LIPOXINS; MACROPHAGE ACTIVATION; MALE; MORPHINE; NEUROGLIA; NF-KAPPA B; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; SPINAL CORD; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84862797405     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.02.009     Document Type: Article

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