Optimisation of synthetic vector systems for cancer gene therapy - the role of the excess of cationic dendrimer under physiological conditions

Current Topics in Medicinal Chemistry

Volumn 14, Issue 9, 2014, Pages 1172-1181

  Santander Ortega, M J ^a,b   de la Fuente, M ^b   Lozano, M V ^b   Tsui, M L ^b   Bolton, K ^b   Uchegbu, I F ^b   Schatzlein A G ^b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cell culture; Dendrimers; Depletion forces; Electrolytes; Gene therapy; Proteins

Indexed keywords

DAB AM16 DENDRIMER; DENDRIMER; UNCLASSIFIED DRUG; CATION; DAB-AM-16; POLYPROPYLENE;

AGAROSE GEL RETARDATION ASSAY; ARTICLE; ASSAY; ATOMIC FORCE MICROSCOPY; BINDING KINETICS; BLOOD COMPATIBILITY; CANCER GENE THERAPY; CELL DEATH; CELL VIABILITY; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION MICROCALORIMETRY; MICROCALORIMETRY; MOUSE; NONHUMAN; PH; PHOTON CORRELATION SPECTROSCOPY; PHYSICAL CHEMISTRY; PRECIPITATION; SYNTHETIC VECTOR SYSTEM; ZETA POTENTIAL; CHEMISTRY; DRUG DELIVERY SYSTEM; GENE THERAPY; GENE TRANSFER; GENETICS; METABOLISM; NEOPLASMS; PROCEDURES; SYNTHESIS; TUMOR CELL LINE;

CATIONS; CELL LINE, TUMOR; DENDRIMERS; DRUG DELIVERY SYSTEMS; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; NEOPLASMS; POLYPROPYLENES;

EID: 84901452719     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026614666140329231718     Document Type: Article

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