-
1
-
-
84856800302
-
Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: crosstalk, shortcuts, and feedbacks
-
Alers S., Löffler A.S., Wesselborg S., Stork B. Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: crosstalk, shortcuts, and feedbacks. Mol. Cell. Biol. 2012, 32:2-11.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 2-11
-
-
Alers, S.1
Löffler, A.S.2
Wesselborg, S.3
Stork, B.4
-
2
-
-
0036744260
-
Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases
-
Ameye L., Young M.F. Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology 2002, 12:107R-116R.
-
(2002)
Glycobiology
, vol.12
-
-
Ameye, L.1
Young, M.F.2
-
3
-
-
84877700624
-
Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis
-
Baghy K., Horváth Z., Regõs E., Kiss K., Schaff Z., Iozzo R.V., Kovalszky I. Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis. FEBS J. 2013, 280:2150-2164.
-
(2013)
FEBS J.
, vol.280
, pp. 2150-2164
-
-
Baghy, K.1
Horváth, Z.2
Regõs, E.3
Kiss, K.4
Schaff, Z.5
Iozzo, R.V.6
Kovalszky, I.7
-
4
-
-
49349109705
-
Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation
-
Bi X., Tong C., Dokendorff A., Banroft L., Gallagher L., Guzman-Hartman G., Iozzo R.V., Augenlicht L.H., Yang W. Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation. Carcinogenesis 2008, 29:1435-1440.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1435-1440
-
-
Bi, X.1
Tong, C.2
Dokendorff, A.3
Banroft, L.4
Gallagher, L.5
Guzman-Hartman, G.6
Iozzo, R.V.7
Augenlicht, L.H.8
Yang, W.9
-
5
-
-
84863012228
-
Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice
-
Bi X., Pohl N.M., Yang G.R., Gou Y., Guzman G., Kajdacsy-Balla A., Iozzo R.V., Yang W. Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice. Carcinogenesis 2012, 33:326-330.
-
(2012)
Carcinogenesis
, vol.33
, pp. 326-330
-
-
Bi, X.1
Pohl, N.M.2
Yang, G.R.3
Gou, Y.4
Guzman, G.5
Kajdacsy-Balla, A.6
Iozzo, R.V.7
Yang, W.8
-
6
-
-
84882577289
-
Role of skeletal muscle proteoglycans during myogenesis
-
Brandan E., Gutierrez J. Role of skeletal muscle proteoglycans during myogenesis. Matrix Biol. 2013, 32:289-297.
-
(2013)
Matrix Biol.
, vol.32
, pp. 289-297
-
-
Brandan, E.1
Gutierrez, J.2
-
7
-
-
78650674666
-
Decorin antagonizes Met receptor activity and downregulates β-catenin and Myc levels
-
Buraschi S., Pal N., Tyler-Rubinstein N., Owens R.T., Neill T., Iozzo R.V. Decorin antagonizes Met receptor activity and downregulates β-catenin and Myc levels. J. Biol. Chem. 2010, 285:42075-42085.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 42075-42085
-
-
Buraschi, S.1
Pal, N.2
Tyler-Rubinstein, N.3
Owens, R.T.4
Neill, T.5
Iozzo, R.V.6
-
8
-
-
84866551287
-
Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model
-
Buraschi S., Neill T., Owens R.T., Iniguez L.A., Purkins G., Vadigepalli R., Evans B., Schaefer L., Peiper S.C., Wang Z., Iozzo R.V. Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. PLoS ONE 2012, 7:e45559.
-
(2012)
PLoS ONE
, vol.7
-
-
Buraschi, S.1
Neill, T.2
Owens, R.T.3
Iniguez, L.A.4
Purkins, G.5
Vadigepalli, R.6
Evans, B.7
Schaefer, L.8
Peiper, S.C.9
Wang, Z.10
Iozzo, R.V.11
-
9
-
-
84879905523
-
Decorin causes autophagy in endothelial cells via Peg3
-
Buraschi S., Neill T., Goyal A., Poluzzi C., Smythies J., Owens R.T., Schaefer L., Torres A.T., Iozzo R.V. Decorin causes autophagy in endothelial cells via Peg3. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:E2582-E2591.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
-
-
Buraschi, S.1
Neill, T.2
Goyal, A.3
Poluzzi, C.4
Smythies, J.5
Owens, R.T.6
Schaefer, L.7
Torres, A.T.8
Iozzo, R.V.9
-
11
-
-
23444458380
-
Increased body fat in mice with a targeted mutation of the paternally expressed imprinted gene Peg3
-
Curley J.P., Pinnock S.B., Dickson S.L., Thresher R., Miyoshi N., Surani M.A., Keverne E.B. Increased body fat in mice with a targeted mutation of the paternally expressed imprinted gene Peg3. FASEB J. 2005, 19:1302-1322.
-
(2005)
FASEB J.
, vol.19
, pp. 1302-1322
-
-
Curley, J.P.1
Pinnock, S.B.2
Dickson, S.L.3
Thresher, R.4
Miyoshi, N.5
Surani, M.A.6
Keverne, E.B.7
-
12
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
Dagda R., Cherra S.J.I., Kulich S.M., Tandon A., Park D., Chu C.T. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J. Biol. Chem. 2009, 284:13843-13855.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13843-13855
-
-
Dagda, R.1
Cherra, S.J.I.2
Kulich, S.M.3
Tandon, A.4
Park, D.5
Chu, C.T.6
-
13
-
-
25144523351
-
Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines
-
Dowdy S.C., Gostout B.S., Shridhar V., Wu X., Smith D.I., Podratz K.C., Jiang S.-W. Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines. Gynecol. Oncol. 2005, 99:126-134.
-
(2005)
Gynecol. Oncol.
, vol.99
, pp. 126-134
-
-
Dowdy, S.C.1
Gostout, B.S.2
Shridhar, V.3
Wu, X.4
Smith, D.I.5
Podratz, K.C.6
Jiang, S.-W.7
-
14
-
-
84855465222
-
Role of autophagy in angiogenesis in aortic endothelial cells
-
Du J., Teng R.-J., Guan T., Eis A., Kaul S., Konduri G.G., Shi Y. Role of autophagy in angiogenesis in aortic endothelial cells. Am. J. Physiol. Cell Physiol. 2012, 302:C383-C391.
-
(2012)
Am. J. Physiol. Cell Physiol.
, vol.302
-
-
Du, J.1
Teng, R.-J.2
Guan, T.3
Eis, A.4
Kaul, S.5
Konduri, G.G.6
Shi, Y.7
-
15
-
-
84889090470
-
Extracellular matrix transcriptome dynamics in hepatocellular carcinoma
-
Duncan M.B. Extracellular matrix transcriptome dynamics in hepatocellular carcinoma. Matrix Biol. 2013, 32:393-398.
-
(2013)
Matrix Biol.
, vol.32
, pp. 393-398
-
-
Duncan, M.B.1
-
16
-
-
84873263577
-
Decorin expression is important for age-related changes in tendon structure and mechanical properties
-
Dunkman A.A., Buckley M.R., Mienaltowski M.J., Adams S.M., Thomas S.J., Satchell L., Kumar A., Pathmanathan L., Beason D.P., Iozzo R.V., Birk D.E., Soslowsky L.J. Decorin expression is important for age-related changes in tendon structure and mechanical properties. Matrix Biol. 2013, 32:3-13.
-
(2013)
Matrix Biol.
, vol.32
, pp. 3-13
-
-
Dunkman, A.A.1
Buckley, M.R.2
Mienaltowski, M.J.3
Adams, S.M.4
Thomas, S.J.5
Satchell, L.6
Kumar, A.7
Pathmanathan, L.8
Beason, D.P.9
Iozzo, R.V.10
Birk, D.E.11
Soslowsky, L.J.12
-
17
-
-
41149093072
-
Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation
-
Feng W., Marquez R.T., Lu Z., Liu J., Lu K.H., Issa J.-P.J., Fishman D.M., Yu Y., Bast R.C. Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down-regulated in human ovarian cancers by loss of heterozygosity and promoter methylation. Cancer 2008, 112:1489-1502.
-
(2008)
Cancer
, vol.112
, pp. 1489-1502
-
-
Feng, W.1
Marquez, R.T.2
Lu, Z.3
Liu, J.4
Lu, K.H.5
Issa, J.-P.J.6
Fishman, D.M.7
Yu, Y.8
Bast, R.C.9
-
18
-
-
37249003185
-
Decorin-transforming growth factor-ß interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices
-
Ferdous Z., Wei V.M., Iozzo R.V., Höök M., Grande-Allen K.J. Decorin-transforming growth factor-ß interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. J. Biol. Chem. 2007, 282:35887-35898.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35887-35898
-
-
Ferdous, Z.1
Wei, V.M.2
Iozzo, R.V.3
Höök, M.4
Grande-Allen, K.J.5
-
19
-
-
84877703267
-
Biological interplay between proteoglycans and their innate immune receptors in inflammation
-
Frey T., Schroeder N., Manon-Jensen T., Iozzo R.V., Schaefer L. Biological interplay between proteoglycans and their innate immune receptors in inflammation. FEBS J. 2013, 280:2165-2179.
-
(2013)
FEBS J.
, vol.280
, pp. 2165-2179
-
-
Frey, T.1
Schroeder, N.2
Manon-Jensen, T.3
Iozzo, R.V.4
Schaefer, L.5
-
20
-
-
77953543377
-
The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond
-
Funderburk S.F., Wang Q.J., Yue Z. The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol. 2010, 20:355-362.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
21
-
-
57349175862
-
Tumor microenvironment: modulation by decorin and related molecules harboring leucine-rich tandem motifs
-
Goldoni S., Iozzo R.V. Tumor microenvironment: modulation by decorin and related molecules harboring leucine-rich tandem motifs. Int. J. Cancer 2008, 123:2473-2479.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 2473-2479
-
-
Goldoni, S.1
Iozzo, R.V.2
-
22
-
-
1342282978
-
Biologically active decorin is a monomer in solution
-
Goldoni S., Owens R.T., McQuillan D.J., Shriver Z., Sasisekharan R., Birk D.E., Campbell S., Iozzo R.V. Biologically active decorin is a monomer in solution. J. Biol. Chem. 2004, 279:6606-6612.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 6606-6612
-
-
Goldoni, S.1
Owens, R.T.2
McQuillan, D.J.3
Shriver, Z.4
Sasisekharan, R.5
Birk, D.E.6
Campbell, S.7
Iozzo, R.V.8
-
23
-
-
51349167280
-
An anti-metastatic role for decorin in breast cancer
-
Goldoni S., Seidler D.G., Heath J., Fassan M., Baffa R., Thakur M.L., Owens R.A., McQuillan D.J., Iozzo R.V. An anti-metastatic role for decorin in breast cancer. Am. J. Pathol. 2008, 173:844-855.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 844-855
-
-
Goldoni, S.1
Seidler, D.G.2
Heath, J.3
Fassan, M.4
Baffa, R.5
Thakur, M.L.6
Owens, R.A.7
McQuillan, D.J.8
Iozzo, R.V.9
-
24
-
-
66149095761
-
Decorin is a novel antagonistic ligand of the Met receptor
-
Goldoni S., Humphries A., Nyström A., Sattar S., Owens R.T., McQuillan D.J., Ireton K., Iozzo R.V. Decorin is a novel antagonistic ligand of the Met receptor. J. Cell Biol. 2009, 185:743-754.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 743-754
-
-
Goldoni, S.1
Humphries, A.2
Nyström, A.3
Sattar, S.4
Owens, R.T.5
McQuillan, D.J.6
Ireton, K.7
Iozzo, R.V.8
-
25
-
-
84871560447
-
Endorepellin affects angiogenesis by antagonizing diverse VEGFR2-evoked signaling pathways: transcriptional repression of HIF-1α and VEGFA and concurrent inhibition of NFAT1 activation
-
Goyal A., Poluzzi C., Willis A.C., Smythies J., Shellard A., Neill T., Iozzo R.V. Endorepellin affects angiogenesis by antagonizing diverse VEGFR2-evoked signaling pathways: transcriptional repression of HIF-1α and VEGFA and concurrent inhibition of NFAT1 activation. J. Biol. Chem. 2012, 287:43543-43556.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 43543-43556
-
-
Goyal, A.1
Poluzzi, C.2
Willis, A.C.3
Smythies, J.4
Shellard, A.5
Neill, T.6
Iozzo, R.V.7
-
26
-
-
0037130464
-
Decorin suppresses tumor cell-mediated angiogenesis
-
Grant D.S., Yenisey C., Rose R.W., Tootell M., Santra M., Iozzo R.V. Decorin suppresses tumor cell-mediated angiogenesis. Oncogene 2002, 21:4765-4777.
-
(2002)
Oncogene
, vol.21
, pp. 4765-4777
-
-
Grant, D.S.1
Yenisey, C.2
Rose, R.W.3
Tootell, M.4
Santra, M.5
Iozzo, R.V.6
-
27
-
-
0034531913
-
A role for decorin in the structural organization of periodontal ligament
-
Häkkinen L., Strassburger S., Kahari V.M., Scott P.G., Eichstetter I., Iozzo R.V., Larjava H. A role for decorin in the structural organization of periodontal ligament. Lab. Invest. 2000, 80:1869-1880.
-
(2000)
Lab. Invest.
, vol.80
, pp. 1869-1880
-
-
Häkkinen, L.1
Strassburger, S.2
Kahari, V.M.3
Scott, P.G.4
Eichstetter, I.5
Iozzo, R.V.6
Larjava, H.7
-
28
-
-
84901415560
-
Decorin deficiency promotes hepatic carcinogenesis
-
Horváth Z., Kovalszky I., Fullár A., Kiss K., Schaff Z., Iozzo R.V., Baghy K. Decorin deficiency promotes hepatic carcinogenesis. Matrix Biol. 2013, 33. 10.1016/j.matbio.2013.11.004.
-
(2013)
Matrix Biol.
, vol.33
-
-
Horváth, Z.1
Kovalszky, I.2
Fullár, A.3
Kiss, K.4
Schaff, Z.5
Iozzo, R.V.6
Baghy, K.7
-
29
-
-
84857485828
-
The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells
-
Ichii M., Frank M.B., Iozzo R.V., Kincade P.W. The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood 2012, 119:1683-1692.
-
(2012)
Blood
, vol.119
, pp. 1683-1692
-
-
Ichii, M.1
Frank, M.B.2
Iozzo, R.V.3
Kincade, P.W.4
-
30
-
-
0027243231
-
Altered proteoglycan gene expression and the tumor stroma
-
Iozzo R.V., Cohen I. Altered proteoglycan gene expression and the tumor stroma. Cell. Mol. Life Sci. 1993, 49:447-455.
-
(1993)
Cell. Mol. Life Sci.
, vol.49
, pp. 447-455
-
-
Iozzo, R.V.1
Cohen, I.2
-
31
-
-
79957605232
-
Proteoglycans in cancer biology, tumour microenvironment and angiogenesis
-
Iozzo R.V., Sanderson R.D. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis. J. Cell. Mol. Med. 2011, 15:1013-1031.
-
(2011)
J. Cell. Mol. Med.
, vol.15
, pp. 1013-1031
-
-
Iozzo, R.V.1
Sanderson, R.D.2
-
32
-
-
77956621814
-
Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans
-
Iozzo R.V., Schaefer L. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans. FEBS J. 2010, 277:3864-3875.
-
(2010)
FEBS J.
, vol.277
, pp. 3864-3875
-
-
Iozzo, R.V.1
Schaefer, L.2
-
33
-
-
0033046972
-
Cooperative action of germline mutations in decorin and p53 accelerates lymphoma tumorigenesis
-
Iozzo R.V., Chakrani F., Perrotti D., McQuillan D.J., Skorski T., Calabretta B., Eichstetter I. Cooperative action of germline mutations in decorin and p53 accelerates lymphoma tumorigenesis. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:3092-3097.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 3092-3097
-
-
Iozzo, R.V.1
Chakrani, F.2
Perrotti, D.3
McQuillan, D.J.4
Skorski, T.5
Calabretta, B.6
Eichstetter, I.7
-
34
-
-
0033582415
-
Decorin is a biological ligand for the epidermal growth factor receptor
-
Iozzo R.V., Moscatello D., McQuillan D.J., Eichstetter I. Decorin is a biological ligand for the epidermal growth factor receptor. J. Biol. Chem. 1999, 274:4489-4492.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 4489-4492
-
-
Iozzo, R.V.1
Moscatello, D.2
McQuillan, D.J.3
Eichstetter, I.4
-
35
-
-
80053402608
-
Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling
-
Iozzo R.V., Buraschi S., Genua M., Xu S.-Q., Solomides C.C., Peiper S.C., Gomella L.G., Owens R.T., Morrione A. Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling. J. Biol. Chem. 2011, 286:34712-34721.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 34712-34721
-
-
Iozzo, R.V.1
Buraschi, S.2
Genua, M.3
Xu, S.-Q.4
Solomides, C.C.5
Peiper, S.C.6
Gomella, L.G.7
Owens, R.T.8
Morrione, A.9
-
36
-
-
84857021943
-
Small leucine-rich proteoglycans
-
Springer, R.P. Mecham (Ed.)
-
Iozzo R.V., Goldoni S., Berendsen A., Young M.F. Small leucine-rich proteoglycans. Extracellular Matrix: An Overview 2011, 197-231. Springer. R.P. Mecham (Ed.).
-
(2011)
Extracellular Matrix: An Overview
, pp. 197-231
-
-
Iozzo, R.V.1
Goldoni, S.2
Berendsen, A.3
Young, M.F.4
-
37
-
-
33747610396
-
A role for decorin in cutaneous wound healing and angiogenesis
-
Järveläinen H., Puolakkainen P., Pakkanen S., Brown E.L., Höök M., Iozzo R.V., Sage H., Wight T.N. A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair Regen. 2006, 14:443-452.
-
(2006)
Wound Repair Regen.
, vol.14
, pp. 443-452
-
-
Järveläinen, H.1
Puolakkainen, P.2
Pakkanen, S.3
Brown, E.L.4
Höök, M.5
Iozzo, R.V.6
Sage, H.7
Wight, T.N.8
-
38
-
-
77950914020
-
The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth
-
Jiang X., Yu Y., Yang H.W., Agar N.Y.R., Frado L., Johnson M.D. The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth. J. Biol. Chem. 2010, 285:8472-8480.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 8472-8480
-
-
Jiang, X.1
Yu, Y.2
Yang, H.W.3
Agar, N.Y.R.4
Frado, L.5
Johnson, M.D.6
-
39
-
-
84859102378
-
Glycosaminoglycans: from "cellular glue" to novel therapeutical agents
-
Karamanos N.K., Tzanakakis G.N. Glycosaminoglycans: from "cellular glue" to novel therapeutical agents. Curr. Opin. Pharmacol. 2012, 12:220-222.
-
(2012)
Curr. Opin. Pharmacol.
, vol.12
, pp. 220-222
-
-
Karamanos, N.K.1
Tzanakakis, G.N.2
-
40
-
-
79961009000
-
Decorin is a novel VEGFR-2-binding antagonist for the human extravillous trophoblast
-
Khan G.A., Girish G.V., Lala N., DiGuglielmo G.M., Lala P.K. Decorin is a novel VEGFR-2-binding antagonist for the human extravillous trophoblast. Mol. Endocrinol. 2011, 25:1431-1443.
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 1431-1443
-
-
Khan, G.A.1
Girish, G.V.2
Lala, N.3
DiGuglielmo, G.M.4
Lala, P.K.5
-
41
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phopshorylation of Ulk1
-
Kim J., Kundu M., Viollet B., Guan K.-L. AMPK and mTOR regulate autophagy through direct phopshorylation of Ulk1. Nat. Cell Biol. 2011, 13:132-141.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.-L.4
-
42
-
-
50049109789
-
AMP-activated protein kinase and human cancer: cancer metabolism revisited
-
Kuhajda F.P. AMP-activated protein kinase and human cancer: cancer metabolism revisited. Int. J. Obes. 2008, 32:536-541.
-
(2008)
Int. J. Obes.
, vol.32
, pp. 536-541
-
-
Kuhajda, F.P.1
-
43
-
-
66449126949
-
Targeted disruption of ROCK1 causes insulin resistance in vivo
-
Lee D.H., Shi J., Jeoung N.H., Kim M.S., Zabolotny J.M., Lee S.W., White M.F., Wei L., Kim B.-K. Targeted disruption of ROCK1 causes insulin resistance in vivo. J. Biol. Chem. 2009, 284:11776-11780.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11776-11780
-
-
Lee, D.H.1
Shi, J.2
Jeoung, N.H.3
Kim, M.S.4
Zabolotny, J.M.5
Lee, S.W.6
White, M.F.7
Wei, L.8
Kim, B.-K.9
-
45
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
46
-
-
84877851087
-
AMPK: a contextual oncogene or tumor suppressor?
-
Liang J., Milson C. AMPK: a contextual oncogene or tumor suppressor?. Cancer Res. 2013, 73:2929-2935.
-
(2013)
Cancer Res.
, vol.73
, pp. 2929-2935
-
-
Liang, J.1
Milson, C.2
-
47
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by Beclin 1
-
Liang X.H., Jackson S., Seaman M., Brown K., Kempkes B., Hibshoosh H., Levine B. Induction of autophagy and inhibition of tumorigenesis by Beclin 1. Nature 1999, 402:672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
48
-
-
80053501671
-
Beclin 1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13
-
Liu J., Xia H., Kim M., Xu L., Li Y., Zhang L., Cai Y., Norber H.V., Zhang T., Furuya T., Jin M., Zhu Z., Wang H., Yu J., Li Y., Hao Y., Choi A., Ke H., Ma D., Yuan J. Beclin 1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell 2011, 147:223-234.
-
(2011)
Cell
, vol.147
, pp. 223-234
-
-
Liu, J.1
Xia, H.2
Kim, M.3
Xu, L.4
Li, Y.5
Zhang, L.6
Cai, Y.7
Norber, H.V.8
Zhang, T.9
Furuya, T.10
Jin, M.11
Zhu, Z.12
Wang, H.13
Yu, J.14
Li, Y.15
Hao, Y.16
Choi, A.17
Ke, H.18
Ma, D.19
Yuan, J.20
more..
-
49
-
-
0034994067
-
Epigenetic silencing of PEG3 gene expression in human glioma cell lines
-
Maegawa S., Yoshioka H., Itaba N., Kubota N., Nishihara S., Shirayoshi Y., Nanba E., Oshimura M. Epigenetic silencing of PEG3 gene expression in human glioma cell lines. Mol. Carcinog. 2001, 31:1-9.
-
(2001)
Mol. Carcinog.
, vol.31
, pp. 1-9
-
-
Maegawa, S.1
Yoshioka, H.2
Itaba, N.3
Kubota, N.4
Nishihara, S.5
Shirayoshi, Y.6
Nanba, E.7
Oshimura, M.8
-
50
-
-
72449168557
-
Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration
-
Merline R., Lazaroski S., Babelova A., Tsalastra-Greul W., Pfeilschifter J., Schluter K.D., Gunther A., Iozzo R.V., Schaefer R.M., Schaefer L. Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration. J. Physiol. Pharmacol. 2009, 60(Suppl. 4):5-13.
-
(2009)
J. Physiol. Pharmacol.
, vol.60
, Issue.SUPPL. 4
, pp. 5-13
-
-
Merline, R.1
Lazaroski, S.2
Babelova, A.3
Tsalastra-Greul, W.4
Pfeilschifter, J.5
Schluter, K.D.6
Gunther, A.7
Iozzo, R.V.8
Schaefer, R.M.9
Schaefer, L.10
-
51
-
-
81455155655
-
Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and microRNA-21
-
Merline R., Moreth K., Beckmann J., Nastase M.V., Zeng-Brouwers J., Tralhão J.G., Lemarchand P., Pfeilschifter J., Schaefer R.M., Iozzo R.V., Schaefer L. Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and microRNA-21. Sci. Signal. 2011, 4:ra75.
-
(2011)
Sci. Signal.
, vol.4
-
-
Merline, R.1
Moreth, K.2
Beckmann, J.3
Nastase, M.V.4
Zeng-Brouwers, J.5
Tralhão, J.G.6
Lemarchand, P.7
Pfeilschifter, J.8
Schaefer, R.M.9
Iozzo, R.V.10
Schaefer, L.11
-
52
-
-
84877715193
-
Small leucine-rich proteoglycans: multifunctional signaling effectors
-
Walter de Gruytier Gmbh and Co., Berlin, N. Karamanos (Ed.)
-
Merline R., Nastase M.V., Iozzo R.V., Schaefer L. Small leucine-rich proteoglycans: multifunctional signaling effectors. Extracellular Matrix: Pathobiology and Signaling 2012, 185-196. Walter de Gruytier Gmbh and Co., Berlin. N. Karamanos (Ed.).
-
(2012)
Extracellular Matrix: Pathobiology and Signaling
, pp. 185-196
-
-
Merline, R.1
Nastase, M.V.2
Iozzo, R.V.3
Schaefer, L.4
-
53
-
-
79953657581
-
Decorin, erythroblastic leukaemia viral oncogene homologue B4 and signal transducer and activator of transcription 3 regulation of semaphorin 3A in central nervous system scar tissue
-
Minor K.H., Bournat J.C., Toscano N., Giger R.J., Davies S.J.A. Decorin, erythroblastic leukaemia viral oncogene homologue B4 and signal transducer and activator of transcription 3 regulation of semaphorin 3A in central nervous system scar tissue. Brain 2011, 134:1140-1155.
-
(2011)
Brain
, vol.134
, pp. 1140-1155
-
-
Minor, K.H.1
Bournat, J.C.2
Toscano, N.3
Giger, R.J.4
Davies, S.J.A.5
-
54
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N., Yoshimori T., Levine B. Methods in mammalian autophagy research. Cell 2010, 140:313-326.
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
55
-
-
84877716242
-
Dichotomy of decorin activity on the insulin-like growth factor-I system
-
Morrione A., Neill T., Iozzo R.V. Dichotomy of decorin activity on the insulin-like growth factor-I system. FEBS J. 2013, 280:2138-2149.
-
(2013)
FEBS J.
, vol.280
, pp. 2138-2149
-
-
Morrione, A.1
Neill, T.2
Iozzo, R.V.3
-
56
-
-
84857308088
-
Decorin antagonizes the angiogenic network. Concurrent inhibition of Met, hipoxia inducible factor-1α and vascular endothelial growth factor A and induction of thrombospondin-1 and TIMP3
-
Neill T., Painter H., Buraschi S., Owens R.T., Lisanti M.P., Schaefer L., Iozzo R.V. Decorin antagonizes the angiogenic network. Concurrent inhibition of Met, hipoxia inducible factor-1α and vascular endothelial growth factor A and induction of thrombospondin-1 and TIMP3. J. Biol. Chem. 2012, 287:5492-5506.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 5492-5506
-
-
Neill, T.1
Painter, H.2
Buraschi, S.3
Owens, R.T.4
Lisanti, M.P.5
Schaefer, L.6
Iozzo, R.V.7
-
57
-
-
84864138010
-
Decorin, a guardian from the matrix
-
Neill T., Schaefer L., Iozzo R.V. Decorin, a guardian from the matrix. Am. J. Pathol. 2012, 181:380-387.
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 380-387
-
-
Neill, T.1
Schaefer, L.2
Iozzo, R.V.3
-
58
-
-
84877701575
-
Decorin evokes rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1
-
Neill T., Jones H.R., Crane-Smith Z., Owens R.T., Schaefer L., Iozzo R.V. Decorin evokes rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1. FEBS J. 2013, 280:2353-2368.
-
(2013)
FEBS J.
, vol.280
, pp. 2353-2368
-
-
Neill, T.1
Jones, H.R.2
Crane-Smith, Z.3
Owens, R.T.4
Schaefer, L.5
Iozzo, R.V.6
-
59
-
-
84885664893
-
Decorin has an appetite for endothelial cell autophagy
-
Neill T., Torres A.T., Buraschi S., Iozzo R.V. Decorin has an appetite for endothelial cell autophagy. Autophagy 2013, 9:1626-1628.
-
(2013)
Autophagy
, vol.9
, pp. 1626-1628
-
-
Neill, T.1
Torres, A.T.2
Buraschi, S.3
Iozzo, R.V.4
-
60
-
-
84867243010
-
The biology of small leucine-rich proteoglycans in bone pathophysiology
-
Nikitovic D., Aggelidakis J., Young M.F., Iozzo R.V., Karamanos N.K., Tzanakakis G.N. The biology of small leucine-rich proteoglycans in bone pathophysiology. J. Biol. Chem. 2012, 287:33926-33933.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 33926-33933
-
-
Nikitovic, D.1
Aggelidakis, J.2
Young, M.F.3
Iozzo, R.V.4
Karamanos, N.K.5
Tzanakakis, G.N.6
-
61
-
-
33645512801
-
Bcl-2 inhibition of autophagy: a new route to cancer?
-
Pattingre S., Levine B. Bcl-2 inhibition of autophagy: a new route to cancer?. Cancer Res. 2006, 66:2885-2888.
-
(2006)
Cancer Res.
, vol.66
, pp. 2885-2888
-
-
Pattingre, S.1
Levine, B.2
-
62
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S., Tassa A., Qu X., Garuti R., Liang X.H., Mizushima N., Packer M., Schneider M.D., Levine B. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005, 122:927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
63
-
-
0141763811
-
The role of decorin in collagen fibrillogenesis and skin homeostasis
-
Reed C.C., Iozzo R.V. The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconj. J. 2002, 19:249-255.
-
(2002)
Glycoconj. J.
, vol.19
, pp. 249-255
-
-
Reed, C.C.1
Iozzo, R.V.2
-
64
-
-
0037161919
-
Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin
-
Reed C.C., Gauldie J., Iozzo R.V. Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene 2002, 21:3688-3695.
-
(2002)
Oncogene
, vol.21
, pp. 3688-3695
-
-
Reed, C.C.1
Gauldie, J.2
Iozzo, R.V.3
-
65
-
-
13944249920
-
Decorin prevents metastatic spreading of breast cancer
-
Reed C.C., Waterhouse A., Kirby S., Kay P., Owens R.A., McQuillan D.J., Iozzo R.V. Decorin prevents metastatic spreading of breast cancer. Oncogene 2005, 24:1104-1110.
-
(2005)
Oncogene
, vol.24
, pp. 1104-1110
-
-
Reed, C.C.1
Waterhouse, A.2
Kirby, S.3
Kay, P.4
Owens, R.A.5
McQuillan, D.J.6
Iozzo, R.V.7
-
66
-
-
84889090216
-
Effects of decorin proteoglycan on fibrillogenesis, ultrastructure, and mechanics of type I collagen gels
-
Reese S.P., Underwood C.J., Weiss J.A. Effects of decorin proteoglycan on fibrillogenesis, ultrastructure, and mechanics of type I collagen gels. Matrix Biol. 2013, 32:414-423.
-
(2013)
Matrix Biol.
, vol.32
, pp. 414-423
-
-
Reese, S.P.1
Underwood, C.J.2
Weiss, J.A.3
-
67
-
-
16244403925
-
Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice
-
Robinson P.S., Huang T.F., Kazam E., Iozzo R.V., Birk D.E., Soslowsky L.J. Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice. J. Biomech. Eng. 2005, 127:181-185.
-
(2005)
J. Biomech. Eng.
, vol.127
, pp. 181-185
-
-
Robinson, P.S.1
Huang, T.F.2
Kazam, E.3
Iozzo, R.V.4
Birk, D.E.5
Soslowsky, L.J.6
-
68
-
-
84866122688
-
Autophagy modulation as a potential therapeutic target for diverse diseases
-
Rubinsztein D.C., Codogno P., Levine B. Autophagy modulation as a potential therapeutic target for diverse diseases. Nat. Rev. Drug Discov. 2012, 11:709-730.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 709-730
-
-
Rubinsztein, D.C.1
Codogno, P.2
Levine, B.3
-
69
-
-
34547796856
-
The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis
-
Rühland C., Schönherr E., Robenek H., Hansen U., Iozzo R.V., Bruckner P., Seidler D.G. The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis. FEBS J. 2007, 274:4246-4255.
-
(2007)
FEBS J.
, vol.274
, pp. 4246-4255
-
-
Rühland, C.1
Schönherr, E.2
Robenek, H.3
Hansen, U.4
Iozzo, R.V.5
Bruckner, P.6
Seidler, D.G.7
-
70
-
-
0030798869
-
Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases
-
Santra M., Mann D.M., Mercer E.W., Skorski T., Calabretta B., Iozzo R.V. Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. J. Clin. Invest. 1997, 100:149-157.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 149-157
-
-
Santra, M.1
Mann, D.M.2
Mercer, E.W.3
Skorski, T.4
Calabretta, B.5
Iozzo, R.V.6
-
71
-
-
0034634669
-
An anti-oncogenic role for decorin: downregulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells
-
Santra M., Eichstetter I., Iozzo R.V. An anti-oncogenic role for decorin: downregulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells. J. Biol. Chem. 2000, 275:35153-35161.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35153-35161
-
-
Santra, M.1
Eichstetter, I.2
Iozzo, R.V.3
-
72
-
-
52049122865
-
Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction
-
Schaefer L., Iozzo R.V. Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction. J. Biol. Chem. 2008, 283:21305-21309.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 21305-21309
-
-
Schaefer, L.1
Iozzo, R.V.2
-
73
-
-
84858450953
-
Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation
-
Schaefer L., Iozzo R.V. Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation. Curr. Opin. Genet. Dev. 2012, 22:56-57.
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 56-57
-
-
Schaefer, L.1
Iozzo, R.V.2
-
75
-
-
10644234507
-
Decorin deficiency leads to impaired angiogenesis in injured mouse cornea
-
Schönherr E., Sunderkotter C., Schaefer L., Thanos S., Grässel S., Oldberg Å., Iozzo R.V., Young M.F., Kresse H. Decorin deficiency leads to impaired angiogenesis in injured mouse cornea. J. Vasc. Res. 2004, 41:499-508.
-
(2004)
J. Vasc. Res.
, vol.41
, pp. 499-508
-
-
Schönherr, E.1
Sunderkotter, C.2
Schaefer, L.3
Thanos, S.4
Grässel, S.5
Oldberg, Å.6
Iozzo, R.V.7
Young, M.F.8
Kresse, H.9
-
77
-
-
67649745754
-
Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan
-
Zhang G., Chen S., Goldoni S., Calder B.W., Simpson H.C., Owens R.T., McQuillan D.J., Young M.F., Iozzo R.V., Birk D.E. Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. J. Biol. Chem. 2009, 284:8888-8897.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8888-8897
-
-
Zhang, G.1
Chen, S.2
Goldoni, S.3
Calder, B.W.4
Simpson, H.C.5
Owens, R.T.6
McQuillan, D.J.7
Young, M.F.8
Iozzo, R.V.9
Birk, D.E.10
-
78
-
-
66449105518
-
A central role for decorin during vertebrate convergent extension
-
Zoeller J.J., Pimtong W., Corby H., Goldoni S., Iozzo A.E., Owens R.T., Ho S.-Y., Iozzo R.V. A central role for decorin during vertebrate convergent extension. J. Biol. Chem. 2009, 284:11728-11737.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11728-11737
-
-
Zoeller, J.J.1
Pimtong, W.2
Corby, H.3
Goldoni, S.4
Iozzo, A.E.5
Owens, R.T.6
Ho, S.-Y.7
Iozzo, R.V.8
|