Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1

FEBS Journal

Volumn 280, Issue 10, 2013, Pages 2353-2368

  Neill, Thomas ^a   Jones, Holly R ^a   Crane Smith, Zoe ^a   Owens, Rick T ^b   Schaefer, Liliana ^c   Iozzo, Renato V ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b LIFECELL CORPORATION   (United States)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

angiogenesis; epidermal growth factor receptor; Met; proteoglycan; receptor tyrosine kinase

Indexed keywords

DECORIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEASOME; PROTEIN KINASE; PROTEIN TYROSINE KINASE; RHO ASSOCIATED COILED COIL CONTAINING PROTEIN KINASE 1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SCATTER FACTOR RECEPTOR; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; VASCULOTROPIN A;

ARTICLE; CARCINOMA CELL; CELL STRAIN; CELL STRAIN MDA MB 231; CONTROLLED STUDY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; HYPOXEMIA; PARACRINE SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TARGETING; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

AMIDES; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CARCINOMA, BASAL CELL; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DECORIN; ENZYME ACTIVATION; EXOSOMES; HUMANS; NEOVASCULARIZATION, PATHOLOGIC; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MET; PYRIDINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; SECRETORY PATHWAY; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR MICROENVIRONMENT;

EID: 84877701575     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12148     Document Type: Article

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