Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and microRNA-21

Science Signaling

Volumn 4, Issue 199, 2011, Pages

  Merline, Rosetta ^a   Moreth, Kristin ^a   Beckmann, Janet ^a   Nastase, Madalina V ^a   Zeng Brouwers, Jinyang ^a   Tralhão, José Guilherme ^b   Lemarchand, Patricia ^c   Pfeilschifter, Josef ^a   Schaefer, Roland M ^d   Iozzo, Renato V ^e   Schaefer, Liliana ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^c UNIVERSITÉ DE NANTES   (France)

^d UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DECORIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 12P70; LIPOPOLYSACCHARIDE; MESSENGER RNA; MICRORNA 21; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; APOPTOSIS REGULATORY PROTEIN; DCN PROTEIN, MOUSE; IL10 PROTEIN, MOUSE; MICRORNA; MIRN21 MICRORNA, MOUSE; PDCD4 PROTEIN, MOUSE; RNA BINDING PROTEIN; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD LEVEL; CANCER THERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG TARGETING; EARLY RESPONSE GENE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE TRANSFER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INNATE IMMUNITY; LUNG; MACROPHAGE; MALE; MOUSE; NEOPLASM; NONHUMAN; PLASMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; SIGNAL TRANSDUCTION; SPLEEN; TUMOR GROWTH; TUMOR IMMUNOLOGY; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; C3H MOUSE; CANCER TRANSPLANTATION; DRUG POTENTIATION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NUDE MOUSE; PATHOLOGY; PERITONEUM MACROPHAGE; TUMOR CELL LINE; XENOGRAFT;

MUS;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; DECORIN; HUMANS; INFLAMMATION; INTERLEUKIN-10; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; MICE, NUDE; MICRORNAS; NEOPLASM TRANSPLANTATION; NEOPLASMS; RNA-BINDING PROTEINS; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; TRANSPLANTATION, HETEROLOGOUS;

EID: 81455155655     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2001868     Document Type: Article

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