메뉴 건너뛰기




Volumn 35, Issue , 2014, Pages 194-205

Decorin deficiency promotes hepatic carcinogenesis

Author keywords

C Myc; Cell signaling; Hepatocarcinogenesis; MSPR RON; Receptor tyrosine kinase; Small leucine rich proteoglycan; Catenin

Indexed keywords

BETA CATENIN; CARCINOGEN; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DECORIN; DIETHYLNITROSAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYC PROTEIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN P21; RETINOBLASTOMA PROTEIN; SOMATOMEDIN C RECEPTOR; THIOACETAMIDE; CDKN1A PROTEIN, MOUSE; EGFR PROTEIN, MOUSE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; PROTEIN TYROSINE KINASE; SOMATOMEDIN RECEPTOR;

EID: 84901415560     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2013.11.004     Document Type: Article
Times cited : (72)

References (97)
  • 3
    • 84877700624 scopus 로고    scopus 로고
    • Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis
    • Baghy K., Horvath Z., Regos E., Kiss K., Schaff Z., Iozzo R.V., Kovalszky I. Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis. FEBS J. 2013, 280:2150-2164.
    • (2013) FEBS J. , vol.280 , pp. 2150-2164
    • Baghy, K.1    Horvath, Z.2    Regos, E.3    Kiss, K.4    Schaff, Z.5    Iozzo, R.V.6    Kovalszky, I.7
  • 4
    • 0020572995 scopus 로고
    • Thioacetamide hepatocarcinogenesis
    • Becker F.F. Thioacetamide hepatocarcinogenesis. J. Natl. Cancer Inst. 1983, 71:553-558.
    • (1983) J. Natl. Cancer Inst. , vol.71 , pp. 553-558
    • Becker, F.F.1
  • 8
    • 84863012228 scopus 로고    scopus 로고
    • Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice
    • Bi X., Pohl N.M., Qian Z., Yang G.R., Gou Y., Guzman G., Kajdacsy-Balla A., Iozzo R.V., Yang W. Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice. Carcinogenesis 2012, 33:326-330.
    • (2012) Carcinogenesis , vol.33 , pp. 326-330
    • Bi, X.1    Pohl, N.M.2    Qian, Z.3    Yang, G.R.4    Gou, Y.5    Guzman, G.6    Kajdacsy-Balla, A.7    Iozzo, R.V.8    Yang, W.9
  • 9
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 10
    • 84882577289 scopus 로고    scopus 로고
    • Role of skeletal muscle proteoglycans during myogenesis
    • Brandan E., Gutierrez J. Role of skeletal muscle proteoglycans during myogenesis. Matrix Biol. 2013, 32:289-297.
    • (2013) Matrix Biol. , vol.32 , pp. 289-297
    • Brandan, E.1    Gutierrez, J.2
  • 11
    • 78650674666 scopus 로고    scopus 로고
    • Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels
    • Buraschi S., Pal N., Tyler-Rubinstein N., Owens R.T., Neill T., Iozzo R.V. Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. J. Biol. Chem. 2010, 285:42075-42085.
    • (2010) J. Biol. Chem. , vol.285 , pp. 42075-42085
    • Buraschi, S.1    Pal, N.2    Tyler-Rubinstein, N.3    Owens, R.T.4    Neill, T.5    Iozzo, R.V.6
  • 14
    • 0030014639 scopus 로고    scopus 로고
    • Liver injury and expression of cytochromes P450: evidence that regulation of CYP2A5 is different from that of other major xenobiotic metabolizing CYP enzymes
    • Camus-Randon A.M., Raffalli F., Bereziat J.C., McGregor D., Konstandi M., Lang M.A. Liver injury and expression of cytochromes P450: evidence that regulation of CYP2A5 is different from that of other major xenobiotic metabolizing CYP enzymes. Toxicol. Appl. Pharmacol. 1996, 138:140-148.
    • (1996) Toxicol. Appl. Pharmacol. , vol.138 , pp. 140-148
    • Camus-Randon, A.M.1    Raffalli, F.2    Bereziat, J.C.3    McGregor, D.4    Konstandi, M.5    Lang, M.A.6
  • 15
    • 84877691193 scopus 로고    scopus 로고
    • The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly
    • Chen S., Birk D.E. The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly. FEBS J. 2013, 280:2120-2137.
    • (2013) FEBS J. , vol.280 , pp. 2120-2137
    • Chen, S.1    Birk, D.E.2
  • 16
    • 0030976443 scopus 로고    scopus 로고
    • Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines
    • Chen Q., Seol D.W., Carr B., Zarnegar R. Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines. Hepatology 1997, 26:59-66.
    • (1997) Hepatology , vol.26 , pp. 59-66
    • Chen, Q.1    Seol, D.W.2    Carr, B.3    Zarnegar, R.4
  • 17
    • 84878604912 scopus 로고    scopus 로고
    • Type 1 insulin-like growth factor receptor monoclonal antibody (HX-1162) treatment for liver cancer
    • Chen X.H., Li Z.Q., Peng H., Jin S.M., Fu H.Q., Zhu T.C., Weng X.G. Type 1 insulin-like growth factor receptor monoclonal antibody (HX-1162) treatment for liver cancer. OncoTargets Ther. 2013, 6:527-530.
    • (2013) OncoTargets Ther. , vol.6 , pp. 527-530
    • Chen, X.H.1    Li, Z.Q.2    Peng, H.3    Jin, S.M.4    Fu, H.Q.5    Zhu, T.C.6    Weng, X.G.7
  • 21
    • 40549131272 scopus 로고    scopus 로고
    • Extracellular matrix dynamics in development and regenerative medicine
    • Daley W.P., Peters S.B., Larsen M. Extracellular matrix dynamics in development and regenerative medicine. J. Cell Sci. 2008, 121:255-264.
    • (2008) J. Cell Sci. , vol.121 , pp. 255-264
    • Daley, W.P.1    Peters, S.B.2    Larsen, M.3
  • 22
    • 0031044872 scopus 로고    scopus 로고
    • Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility
    • Danielson K.G., Baribault H., Holmes D.F., Graham H., Kadler K.E., Iozzo R.V. Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J. Cell Biol. 1997, 136:729-743.
    • (1997) J. Cell Biol. , vol.136 , pp. 729-743
    • Danielson, K.G.1    Baribault, H.2    Holmes, D.F.3    Graham, H.4    Kadler, K.E.5    Iozzo, R.V.6
  • 23
  • 24
    • 0029785662 scopus 로고    scopus 로고
    • Decorin-induced growth suppression is associated with up-regulation of p21, an inhibitor of cyclin-dependent kinases
    • De Luca A., Santra M., Baldi A., Giordano A., Iozzo R.V. Decorin-induced growth suppression is associated with up-regulation of p21, an inhibitor of cyclin-dependent kinases. J. Biol. Chem. 1996, 271:18961-18965.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18961-18965
    • De Luca, A.1    Santra, M.2    Baldi, A.3    Giordano, A.4    Iozzo, R.V.5
  • 25
    • 17944362596 scopus 로고    scopus 로고
    • Expression of decorin, transforming growth factor-beta 1, tissue inhibitor metalloproteinase 1 and 2, and type IV collagenases in chronic hepatitis
    • Dudas J., Kovalszky I., Gallai M., Nagy J.O., Schaff Z., Knittel T., Mehde M., Neubauer K., Szalay F., Ramadori G. Expression of decorin, transforming growth factor-beta 1, tissue inhibitor metalloproteinase 1 and 2, and type IV collagenases in chronic hepatitis. Am. J. Clin. Pathol. 2001, 115:725-735.
    • (2001) Am. J. Clin. Pathol. , vol.115 , pp. 725-735
    • Dudas, J.1    Kovalszky, I.2    Gallai, M.3    Nagy, J.O.4    Schaff, Z.5    Knittel, T.6    Mehde, M.7    Neubauer, K.8    Szalay, F.9    Ramadori, G.10
  • 27
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag H.B., Rudolph K.L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007, 132:2557-2576.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 28
    • 0021601376 scopus 로고
    • The multistep nature of cancer development
    • Farber E. The multistep nature of cancer development. Cancer Res. 1984, 44:4217-4223.
    • (1984) Cancer Res. , vol.44 , pp. 4217-4223
    • Farber, E.1
  • 32
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • Grimes C.A., Jope R.S. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog. Neurobiol. 2001, 65:391-426.
    • (2001) Prog. Neurobiol. , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 34
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993, 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 37
    • 68849118378 scopus 로고    scopus 로고
    • Experimental mouse models for hepatocellular carcinoma research
    • Heindryckx F., Colle I., Van Vlierberghe H. Experimental mouse models for hepatocellular carcinoma research. Int. J. Exp. Pathol. 2009, 90:367-386.
    • (2009) Int. J. Exp. Pathol. , vol.90 , pp. 367-386
    • Heindryckx, F.1    Colle, I.2    Van Vlierberghe, H.3
  • 38
    • 84859738657 scopus 로고    scopus 로고
    • Breast cancer cell-derived matrix supports vascular morphogenesis
    • Hielscher A.C., Qiu C., Gerecht S. Breast cancer cell-derived matrix supports vascular morphogenesis. Am. J. Physiol. Cell Physiol. 2012, 302:C1243-C1256.
    • (2012) Am. J. Physiol. Cell Physiol. , vol.302
    • Hielscher, A.C.1    Qiu, C.2    Gerecht, S.3
  • 39
    • 77956471611 scopus 로고    scopus 로고
    • Convergence between Wnt-beta-catenin and EGFR signaling in cancer
    • Hu T., Li C. Convergence between Wnt-beta-catenin and EGFR signaling in cancer. Mol. Cancer 2010, 9:236.
    • (2010) Mol. Cancer , vol.9 , pp. 236
    • Hu, T.1    Li, C.2
  • 40
    • 70149091269 scopus 로고    scopus 로고
    • Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways
    • Hu Y., Sun H., Owens R.T., Wu J., Chen Y.Q., Berquin I.M., Perry D., O'Flaherty J.T., Edwards I.J. Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways. Neoplasia 2009, 11:1042-1053.
    • (2009) Neoplasia , vol.11 , pp. 1042-1053
    • Hu, Y.1    Sun, H.2    Owens, R.T.3    Wu, J.4    Chen, Y.Q.5    Berquin, I.M.6    Perry, D.7    O'Flaherty, J.T.8    Edwards, I.J.9
  • 41
    • 70849099495 scopus 로고    scopus 로고
    • The extracellular matrix: not just pretty fibrils
    • (New York, N.Y.)
    • Hynes R.O. The extracellular matrix: not just pretty fibrils. Science 2009, 326:1216-1219. (New York, N.Y.).
    • (2009) Science , vol.326 , pp. 1216-1219
    • Hynes, R.O.1
  • 42
    • 84857485828 scopus 로고    scopus 로고
    • The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells
    • Ichii M., Frank M.B., Iozzo R.V., Kincade P.W. The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood 2012, 119:1683-1692.
    • (2012) Blood , vol.119 , pp. 1683-1692
    • Ichii, M.1    Frank, M.B.2    Iozzo, R.V.3    Kincade, P.W.4
  • 43
    • 0033516558 scopus 로고    scopus 로고
    • The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins
    • Iozzo R.V. The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins. J. Biol. Chem. 1999, 274:18843-18846.
    • (1999) J. Biol. Chem. , vol.274 , pp. 18843-18846
    • Iozzo, R.V.1
  • 44
    • 0027243231 scopus 로고
    • Altered proteoglycan gene expression and the tumor stroma
    • Iozzo R.V., Cohen I. Altered proteoglycan gene expression and the tumor stroma. Experientia 1993, 49:447-455.
    • (1993) Experientia , vol.49 , pp. 447-455
    • Iozzo, R.V.1    Cohen, I.2
  • 45
    • 0030010512 scopus 로고    scopus 로고
    • Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function
    • Iozzo R.V., Murdoch A.D. Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function. Faseb J. 1996, 10:598-614.
    • (1996) Faseb J. , vol.10 , pp. 598-614
    • Iozzo, R.V.1    Murdoch, A.D.2
  • 46
    • 79957605232 scopus 로고    scopus 로고
    • Proteoglycans in cancer biology, tumour microenvironment and angiogenesis
    • Iozzo R.V., Sanderson R.D. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis. J. Cell. Mol. Med. 2011, 15:1013-1031.
    • (2011) J. Cell. Mol. Med. , vol.15 , pp. 1013-1031
    • Iozzo, R.V.1    Sanderson, R.D.2
  • 47
    • 77956621814 scopus 로고    scopus 로고
    • Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans
    • Iozzo R.V., Schaefer L. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans. FEBS J. 2010, 277:3864-3875.
    • (2010) FEBS J. , vol.277 , pp. 3864-3875
    • Iozzo, R.V.1    Schaefer, L.2
  • 49
    • 0033582415 scopus 로고    scopus 로고
    • Decorin is a biological ligand for the epidermal growth factor receptor
    • Iozzo R.V., Moscatello D.K., McQuillan D.J., Eichstetter I. Decorin is a biological ligand for the epidermal growth factor receptor. J. Biol. Chem. 1999, 274:4489-4492.
    • (1999) J. Biol. Chem. , vol.274 , pp. 4489-4492
    • Iozzo, R.V.1    Moscatello, D.K.2    McQuillan, D.J.3    Eichstetter, I.4
  • 52
    • 77953464861 scopus 로고    scopus 로고
    • Molecular genetics of hepatocellular neoplasia
    • Jain S., Singhal S., Lee P., Xu R. Molecular genetics of hepatocellular neoplasia. Am. J. Transl. Res. 2010, 2:105-118.
    • (2010) Am. J. Transl. Res. , vol.2 , pp. 105-118
    • Jain, S.1    Singhal, S.2    Lee, P.3    Xu, R.4
  • 54
    • 65949100126 scopus 로고    scopus 로고
    • The c-MYC-AP4-p21 cascade
    • Jung P., Hermeking H. The c-MYC-AP4-p21 cascade. Cell cycle 2009, 8:982-989.
    • (2009) Cell cycle , vol.8 , pp. 982-989
    • Jung, P.1    Hermeking, H.2
  • 55
    • 79961009000 scopus 로고    scopus 로고
    • Decorin is a novel VEGFR-2-binding antagonist for the human extravillous trophoblast
    • Khan G.A., Girish G.V., Lala N., Di Guglielmo G.M., Lala P.K. Decorin is a novel VEGFR-2-binding antagonist for the human extravillous trophoblast. Mol. Endocrinol. 2011, 25:1431-1443.
    • (2011) Mol. Endocrinol. , vol.25 , pp. 1431-1443
    • Khan, G.A.1    Girish, G.V.2    Lala, N.3    Di Guglielmo, G.M.4    Lala, P.K.5
  • 56
    • 0036234628 scopus 로고    scopus 로고
    • Functional and genomic implications of global gene expression profiles in cell lines from human hepatocellular cancer
    • Lee J.S., Thorgeirsson S.S. Functional and genomic implications of global gene expression profiles in cell lines from human hepatocellular cancer. Hepatology 2002, 35:1134-1143.
    • (2002) Hepatology , vol.35 , pp. 1134-1143
    • Lee, J.S.1    Thorgeirsson, S.S.2
  • 58
    • 84882794927 scopus 로고    scopus 로고
    • Age-dependent alterations of decorin glycosaminoglycans in human skin
    • Li Y., Liu Y., Xia W., Lei D., Voorhees J.J., Fisher G.J. Age-dependent alterations of decorin glycosaminoglycans in human skin. Sci. Rep. 2013, 3:2422.
    • (2013) Sci. Rep. , vol.3 , pp. 2422
    • Li, Y.1    Liu, Y.2    Xia, W.3    Lei, D.4    Voorhees, J.J.5    Fisher, G.J.6
  • 59
  • 60
    • 0037108681 scopus 로고    scopus 로고
    • Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital
    • Loeppen S., Schneider D., Gaunitz F., Gebhardt R., Kurek R., Buchmann A., Schwarz M. Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital. Cancer Res. 2002, 62:5685-5688.
    • (2002) Cancer Res. , vol.62 , pp. 5685-5688
    • Loeppen, S.1    Schneider, D.2    Gaunitz, F.3    Gebhardt, R.4    Kurek, R.5    Buchmann, A.6    Schwarz, M.7
  • 61
    • 84871721848 scopus 로고    scopus 로고
    • Clinical implications of deregulated CDK4 and Cyclin D1 expression in patients with human hepatocellular carcinoma
    • Lu J.W., Lin Y.M., Chang J.G., Yeh K.T., Chen R.M., Tsai J.J., Su W.W., Hu R.M. Clinical implications of deregulated CDK4 and Cyclin D1 expression in patients with human hepatocellular carcinoma. Med. Oncol. 2013, 30:379.
    • (2013) Med. Oncol. , vol.30 , pp. 379
    • Lu, J.W.1    Lin, Y.M.2    Chang, J.G.3    Yeh, K.T.4    Chen, R.M.5    Tsai, J.J.6    Su, W.W.7    Hu, R.M.8
  • 64
    • 84877716242 scopus 로고    scopus 로고
    • Dichotomy of decorin activity on the insulin-like growth factor-I system
    • Morrione A., Neill T., Iozzo R.V. Dichotomy of decorin activity on the insulin-like growth factor-I system. FEBS J. 2013, 280:2138-2149.
    • (2013) FEBS J. , vol.280 , pp. 2138-2149
    • Morrione, A.1    Neill, T.2    Iozzo, R.V.3
  • 65
    • 84857308088 scopus 로고    scopus 로고
    • Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1alpha, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3
    • Neill T., Painter H., Buraschi S., Owens R.T., Lisanti M.P., Schaefer L., Iozzo R.V. Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1alpha, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3. J. Biol. Chem. 2012, 287:5492-5506.
    • (2012) J. Biol. Chem. , vol.287 , pp. 5492-5506
    • Neill, T.1    Painter, H.2    Buraschi, S.3    Owens, R.T.4    Lisanti, M.P.5    Schaefer, L.6    Iozzo, R.V.7
  • 66
  • 67
    • 84877701575 scopus 로고    scopus 로고
    • Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1
    • Neill T., Jones H.R., Crane-Smith Z., Owens R.T., Schaefer L., Iozzo R.V. Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1. FEBS J. 2013, 280:2353-2368.
    • (2013) FEBS J. , vol.280 , pp. 2353-2368
    • Neill, T.1    Jones, H.R.2    Crane-Smith, Z.3    Owens, R.T.4    Schaefer, L.5    Iozzo, R.V.6
  • 69
    • 74049108220 scopus 로고    scopus 로고
    • Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity
    • Nystrom A., Shaik Z.P., Gullberg D., Krieg T., Eckes B., Zent R., Pozzi A., Iozzo R.V. Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood 2009, 114:4897-4906.
    • (2009) Blood , vol.114 , pp. 4897-4906
    • Nystrom, A.1    Shaik, Z.P.2    Gullberg, D.3    Krieg, T.4    Eckes, B.5    Zent, R.6    Pozzi, A.7    Iozzo, R.V.8
  • 70
    • 84866369296 scopus 로고    scopus 로고
    • Novel strategies for hepatocellular carcinoma based on MMPs science
    • Okazaki I., Inagaki Y. Novel strategies for hepatocellular carcinoma based on MMPs science. Anti Cancer Agents Med. Chem. 2012, 12:753-763.
    • (2012) Anti Cancer Agents Med. Chem. , vol.12 , pp. 753-763
    • Okazaki, I.1    Inagaki, Y.2
  • 71
    • 67649219059 scopus 로고    scopus 로고
    • PDGFRalpha: a new therapeutic target in the treatment of hepatocellular carcinoma?
    • Oseini A.M., Roberts L.R. PDGFRalpha: a new therapeutic target in the treatment of hepatocellular carcinoma?. Expert Opin. Ther. Targets 2009, 13:443-454.
    • (2009) Expert Opin. Ther. Targets , vol.13 , pp. 443-454
    • Oseini, A.M.1    Roberts, L.R.2
  • 72
    • 0141763811 scopus 로고    scopus 로고
    • The role of decorin in collagen fibrillogenesis and skin homeostasis
    • Reed C.C., Iozzo R.V. The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconj. J. 2002, 19:249-255.
    • (2002) Glycoconj. J. , vol.19 , pp. 249-255
    • Reed, C.C.1    Iozzo, R.V.2
  • 73
    • 0037161919 scopus 로고    scopus 로고
    • Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin
    • Reed C.C., Gauldie J., Iozzo R.V. Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene 2002, 21:3688-3695.
    • (2002) Oncogene , vol.21 , pp. 3688-3695
    • Reed, C.C.1    Gauldie, J.2    Iozzo, R.V.3
  • 75
    • 77951679998 scopus 로고    scopus 로고
    • Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells
    • Rivadeneira D.B., Mayhew C.N., Thangavel C., Sotillo E., Reed C.A., Grana X., Knudsen E.S. Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells. Gastroenterology 2010, 138:1920-1930.
    • (2010) Gastroenterology , vol.138 , pp. 1920-1930
    • Rivadeneira, D.B.1    Mayhew, C.N.2    Thangavel, C.3    Sotillo, E.4    Reed, C.A.5    Grana, X.6    Knudsen, E.S.7
  • 76
    • 16244403925 scopus 로고    scopus 로고
    • Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice
    • Robinson P.S., Huang T.F., Kazam E., Iozzo R.V., Birk D.E., Soslowsky L.J. Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice. J. Biomech. Eng. 2005, 127:181-185.
    • (2005) J. Biomech. Eng. , vol.127 , pp. 181-185
    • Robinson, P.S.1    Huang, T.F.2    Kazam, E.3    Iozzo, R.V.4    Birk, D.E.5    Soslowsky, L.J.6
  • 77
    • 77951234989 scopus 로고    scopus 로고
    • The extracellular matrix in development and morphogenesis: a dynamic view
    • Rozario T., DeSimone D.W. The extracellular matrix in development and morphogenesis: a dynamic view. Dev. Biol. 2010, 341:126-140.
    • (2010) Dev. Biol. , vol.341 , pp. 126-140
    • Rozario, T.1    DeSimone, D.W.2
  • 78
    • 0026080765 scopus 로고
    • Proteoglycans as modulators of growth factor activities
    • Ruoslahti E., Yamaguchi Y. Proteoglycans as modulators of growth factor activities. Cell 1991, 64:867-869.
    • (1991) Cell , vol.64 , pp. 867-869
    • Ruoslahti, E.1    Yamaguchi, Y.2
  • 79
    • 0030798869 scopus 로고    scopus 로고
    • Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases
    • Santra M., Mann D.M., Mercer E.W., Skorski T., Calabretta B., Iozzo R.V. Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. J. Clin. Invest. 1997, 100:149-157.
    • (1997) J. Clin. Invest. , vol.100 , pp. 149-157
    • Santra, M.1    Mann, D.M.2    Mercer, E.W.3    Skorski, T.4    Calabretta, B.5    Iozzo, R.V.6
  • 80
    • 84858450953 scopus 로고    scopus 로고
    • Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation
    • Schaefer L., Iozzo R.V. Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation. Curr. Opin. Genet. Dev. 2012, 22:56-57.
    • (2012) Curr. Opin. Genet. Dev. , vol.22 , pp. 56-57
    • Schaefer, L.1    Iozzo, R.V.2
  • 82
    • 18144431289 scopus 로고    scopus 로고
    • Decorin, a novel player in the insulin-like growth factor system
    • Schonherr E., Sunderkotter C., Iozzo R.V., Schaefer L. Decorin, a novel player in the insulin-like growth factor system. J. Biol. Chem. 2005, 280:15767-15772.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15767-15772
    • Schonherr, E.1    Sunderkotter, C.2    Iozzo, R.V.3    Schaefer, L.4
  • 83
    • 84867745182 scopus 로고    scopus 로고
    • The galactosaminoglycan-containing decorin and its impact on diseases
    • Seidler D.G. The galactosaminoglycan-containing decorin and its impact on diseases. Curr. Opin. Struct. Biol. 2012, 22:578-582.
    • (2012) Curr. Opin. Struct. Biol. , vol.22 , pp. 578-582
    • Seidler, D.G.1
  • 84
    • 58149350127 scopus 로고    scopus 로고
    • Decorin and its galactosaminoglycan chain: extracellular regulator of cellular function?
    • Seidler D.G., Dreier R. Decorin and its galactosaminoglycan chain: extracellular regulator of cellular function?. IUBMB life 2008, 60:729-733.
    • (2008) IUBMB life , vol.60 , pp. 729-733
    • Seidler, D.G.1    Dreier, R.2
  • 86
    • 84865240172 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: important biomarkers and their significance in molecular diagnostics and therapy
    • Sengupta B., Siddiqi S.A. Hepatocellular carcinoma: important biomarkers and their significance in molecular diagnostics and therapy. Curr. Med. Chem. 2012, 19:3722-3729.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 3722-3729
    • Sengupta, B.1    Siddiqi, S.A.2
  • 87
    • 77954531753 scopus 로고    scopus 로고
    • Epidemiology of hepatocellular carcinoma
    • Sherman M. Epidemiology of hepatocellular carcinoma. Oncology 2010, 78(Suppl. 1):7-10.
    • (2010) Oncology , vol.78 , Issue.SUPPL. 1 , pp. 7-10
    • Sherman, M.1
  • 88
    • 84870362178 scopus 로고    scopus 로고
    • More than matrix: the multifaceted role of decorin in cancer
    • Sofeu Feugaing D.D., Gotte M., Viola M. More than matrix: the multifaceted role of decorin in cancer. Eur. J. Cell Biol. 2013, 92:1-11.
    • (2013) Eur. J. Cell Biol. , vol.92 , pp. 1-11
    • Sofeu Feugaing, D.D.1    Gotte, M.2    Viola, M.3
  • 89
    • 34447326697 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor-alpha: a novel therapeutic target in human hepatocellular cancer
    • Stock P., Monga D., Tan X., Micsenyi A., Loizos N., Monga S.P. Platelet-derived growth factor receptor-alpha: a novel therapeutic target in human hepatocellular cancer. Mol. Cancer Ther. 2007, 6:1932-1941.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1932-1941
    • Stock, P.1    Monga, D.2    Tan, X.3    Micsenyi, A.4    Loizos, N.5    Monga, S.P.6
  • 92
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • Whittaker S., Marais R., Zhu A.X. The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene 2010, 29:4989-5005.
    • (2010) Oncogene , vol.29 , pp. 4989-5005
    • Whittaker, S.1    Marais, R.2    Zhu, A.X.3
  • 93
    • 79959848106 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor axis in hepatocellular carcinoma
    • Wu J., Zhu A.X. Targeting insulin-like growth factor axis in hepatocellular carcinoma. J. Hematol. Oncol. 2011, 4:30.
    • (2011) J. Hematol. Oncol. , vol.4 , pp. 30
    • Wu, J.1    Zhu, A.X.2
  • 94
    • 0025353729 scopus 로고
    • Negative regulation of transforming growth factor-beta by the proteoglycan decorin
    • Yamaguchi Y., Mann D.M., Ruoslahti E. Negative regulation of transforming growth factor-beta by the proteoglycan decorin. Nature 1990, 346:281-284.
    • (1990) Nature , vol.346 , pp. 281-284
    • Yamaguchi, Y.1    Mann, D.M.2    Ruoslahti, E.3
  • 97
    • 25444503249 scopus 로고    scopus 로고
    • Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis
    • Zhu J.X., Goldoni S., Bix G., Owens R.T., McQuillan D.J., Reed C.C., Iozzo R.V. Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. J. Biol. Chem. 2005, 280:32468-32479.
    • (2005) J. Biol. Chem. , vol.280 , pp. 32468-32479
    • Zhu, J.X.1    Goldoni, S.2    Bix, G.3    Owens, R.T.4    McQuillan, D.J.5    Reed, C.C.6    Iozzo, R.V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.