The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth

Journal of Biological Chemistry

Volumn 285, Issue 11, 2010, Pages 8472-8480

  Jiang, Xiuli ^a   Yu, Yi ^a   Yang, Hong Wei ^a   Agar, Nathalie Y R ^a   Frado, Laura ^a   Johnson, Mark D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; GROWTH AND DEVELOPMENT; HUMAN CELLS; HYPERMETHYLATION; LOSS OF IMPRINTINGS; MOLECULAR MECHANISM; MRNA EXPRESSION; OVER-EXPRESSION; PROTEASOMAL PATHWAY; PROTEIN EXPRESSIONS; TUMOR GRADES; TUMOR SUPPRESSION; WNT PATHWAY; WNT SIGNALING; ZEBRAFISH;

CELL DEATH; MAMMALS; PROTEINS; SIGNALING; TUMORS;

STEM CELLS;

BETA CATENIN; CD133 ANTIGEN; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; PATERNALLY EXPRESSED GENE 3 PROTEIN; PROTEASOME; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; WNT PROTEIN; CTNNB1 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; PEG3 PROTEIN, HUMAN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GRADING; CANCER INHIBITION; CANCER STEM CELL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC REGULATION; GENOME IMPRINTING; GLIOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TAIL; ZEBRA FISH; ANIMAL; BRAIN TUMOR; CELL DIVISION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

DANIO RERIO; MAMMALIA;

ANIMALS; APOPTOSIS; BETA CATENIN; BRAIN NEOPLASMS; CELL DIVISION; CELL LINE, TUMOR; DNA METHYLATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC IMPRINTING; GLIOMA; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SIGNAL TRANSDUCTION; WNT PROTEINS; ZEBRAFISH;

EID: 77950914020     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.069450     Document Type: Article

References (37)

1. Relaix, F., Weng, X., Marazzi, G., Yang, E., Copeland, N., Jenkins, N., Spence, S. E., and Sassoon, D. (1996) Dev. Biol. 177, 383-396
2. Kim, J., Ashworth, L., Branscomb, E., and Stubbs, L. (1997) Genome Res. 7, 532-540
3. Li, L., Keverne, E. B., Aparicio, S. A., Ishino, F., Barton, S. C., and Surani, M. A. (1999) Science 284, 330-333
4. Yamaguchi, A., Taniguchi, M., Hori, O., Ogawa, S., Tojo, N., Matsuoka, N., Miyake, S., Kasai, K., Sugimoto, H., Tamatani, M., Yamashita, T., and Tohyama, M. (2002) J. Biol. Chem. 277, 623-629
5. Curley, J. P., Pinnock, S. B., Dickson, S. L., Thresher, R., Miyoshi, N., Surani, M. A., and Keverne, E. B. (2005) FASEB J. 19, 1302-1304
6. Swaney, W. T., Curley, J. P., Champagne, F. A., and Keverne, E. B. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 6084-6089
7. Swaney, W. T., Curley, J. P., Champagne, F. A., and Keverne, E. B. (2008) Behav. Neurosci. 122, 963-973
8. Relaix, F., Wei, X. J., Wu, X., and Sassoon, D. A. (1998) Nat. Genet. 18, 287-291
9. Ledgerwood, E. C., O'Rahilly, S., and Surani, M. A. (2000) Lab. Invest. 80, 1509-1511
10. Coletti, D., Yang, E., Marazzi, G., and Sassoon, D. (2002) EMBO J. 21, 631-642
11. Nicolas, N., Marazzi, G., Kelley, K., and Sassoon, D. (2005) Dev. Biol. 281, 171-183
12. Schwarzkopf, M., Coletti, D., Sassoon, D., and Marazzi, G. (2006) Genes Dev. 20, 3440-3452
13. Relaix, F., Wei, X., Li, W., Pan, J., Lin, Y., Bowtell, D. D., Sassoon, D. A., and Wu, X. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 2105-2110
14. Deng, Y., and Wu, X. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 12050-12055
15. Johnson, M. D., Wu, X., Aithmitti, N., and Morrison, R. S. (2002) J. Biol. Chem. 277, 23000-23007
16. Okamoto, K., Morison, I. M., Taniguchi, T., and Reeve, A. E. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 5367-5371
17. Pantoja, C., de Los Ríos, L., Matheu, A., Antequera, F., and Serrano, M. (2005) Cancer Res. 65, 26-33
18. Maegawa, S., Yoshioka, H., Itaba, N., Kubota, N., Nishihara, S., Shirayoshi, Y., Nanba, E., and Oshimura, M. (2001) Mol. Carcinog. 31, 1-9
19. Dowdy, S. C., Gostout, B. S., Shridhar, V., Wu, X., Smith, D. I., Podratz, K. C., and Jiang, S. W. (2005) Gynecol. Oncol. 99, 126-134
20. Kohda, T., Asai, A., Kuroiwa, Y., Kobayashi, S., Aisaka, K., Nagashima, G., Yoshida, M. C., Kondo, Y., Kagiyama, N., Kirino, T., Kaneko-Ishino, T., and Ishino, F. (2001) Genes Cells 6, 237-247
21. Yu, Y., Jiang, X., Schoch, B. S., Carroll, R. S., Black, P. M., and Johnson, M. D. (2007) Cancer Res. 67, 130-138
22. Santelli, E., Leone, M., Li, C., Fukushima, T., Preece, N. E., Olson, A. J., Ely, K. R., Reed, J. C., Pellecchia, M., Liddington, R. C., and Matsuzawa, S. (2005) J. Biol. Chem. 280, 34278-34287
23. Sadot, E., Conacci-Sorrell, M., Zhurinsky, J., Shnizer, D., Lando, Z., Zharhary, D., Kam, Z., Ben-Ze'ev, A., and Geiger, B. (2002) J. Cell Sci. 115, 2771-2780
24. Wang, Z., Vogelstein, B., and Kinzler, K. W. (2003) Cancer Res. 63, 5234-5235
25. Thorpe, C. J., Weidinger, G., and Moon, R. T. (2005) Development 132, 1763-1772
26. Kim, J., Bergmann, A., and Stubbs, L. (2000) Genomics 64, 114-118
27. Edelstein, L. C., and Collins, T. (2005) Gene 359, 1-17
28. Matsuzawa, S. I., and Reed, J. C. (2001) Mol. Cell 7, 915-926
29. Liu, J., Stevens, J., Rote, C. A., Yost, H. J., Hu, Y., Neufeld, K. L., White, R. L., and Matsunami, N. (2001) Mol. Cell 7, 927-936
30. Moon, R. T., Kohn, A. D., De Ferrari, G. V., and Kaykas, A. (2004) Nat. Rev. Genet. 5, 691-701
31. Singh, S. K., Hawkins, C., Clarke, I. D., Squire, J. A., Bayani, J., Hide, T., Henkelman, R. M., Cusimano, M. D., and Dirks, P. B. (2004) Nature 432, 396-401
32. Borello, U., Berarducci, B., Murphy, P., Bajard, L., Buffa, V., Piccolo, S., Buckingham, M., and Cossu, G. (2006) Development 133, 3723-3732
33. Kapsimali, M., Caneparo, L., Houart, C., and Wilson, S. W. (2004) Development 131, 5923-5933
34. Huang, M., Wang, Y., Sun, D., Zhu, H., Yin, Y., Zhang, W., Yang, S., Quan, L., Bai, J., Wang, S., Chen, Q., Li, S., and Xu, N. (2006) BMC Cancer 6, 221
35. Zhang, Z., Hartmann, H., Do, V. M., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., van de Wetering, M., Clevers, H., Saftig, P., De Strooper, B., He, X., and Yankner, B. A. (1998) Nature 395, 698-702
36. Johnson, M. D., Yu, L. R., Conrads, T. P., Kinoshita, Y., Uo, T., Matthews, J. D., Lee, S. W., Smith, R. D., Veenstra, T. D., and Morrison, R. S. (2004) J. Biol. Chem. 279, 26685-26697
37. Li, H. L., Wang, H. H., Liu, S. J., Deng, Y. Q., Zhang, Y. J., Tian, Q., Wang, X. C., Chen, X. Q., Yang, Y., Zhang, J. Y., Wang, Q., Xu, H., Liao, F. F., and Wang, J. Z. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 3591-3596