Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain

Nature Medicine

Volumn 10, Issue 1, 2004, Pages 93-97

  Windrem, Martha S ^a   Nunes, Marta C ^a   Rashbaum, William K ^a   Schwartz, Theodore H ^a   Goodman, Robert A ^b   McKhann II, Guy ^b   Roy, Neeta S ^a   Goldman, Steven A ^a,c  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Columbia University Medical School ^*  (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN; MYELIN BASIC PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL MATURATION; CONTROLLED STUDY; DEMYELINATING DISEASE; FETUS; FETUS CELL; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; MOUSE; MYELINATION; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHIVERING; STEM CELL; WHITE MATTER; XENOGRAFT; ANIMAL; BIOSYNTHESIS; CONFOCAL MICROSCOPY; CYTOLOGY; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; PATHOLOGY;

ANIMALIA;

ADULT; ANIMALS; DEMYELINATING DISEASES; FETUS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MYELIN BASIC PROTEINS; OLIGODENDROGLIA; STEM CELLS;

EID: 1542336187     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm974     Document Type: Article

References (25)

1. Lachapelle, F., Gumpel, M., Baulac, C. & Jacque, C. Transplantation of fragments of CNS into the brains of shiverer mutant mice: extensive myelination by transplanted oligodendrocytes. Dev. Neurosci. 6, 326-334 (1983).
2. Roach, A., Takahashi, N., Pravtcheva, D., Ruddle, F. & Hood, L. Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice. Cell 42, 149-155 (1985).
3. Gansmuller, A. et al. Transplantations of newborn CNS fragments into the brain of shiverer mutant mice: extensive myelination by transplanted oligodendrocytes. II. Electron microscopic study. Dev. Neurosci. 8, 197-207 (1986).
4. Gumpel, M. et al. Transplantation of human embryonic oligodendrocytes into shiverer brain. Ann. NY Acad. Sci. 495, 71-85 (1987).
5. Gumpel, M., Gout, O., Lubetzki, C., Gansmuller, A. & Baumann, N. Myelination and remyelination in the central nervous system by transplanted oligodendrocytes using the shiverer model. Discussion on the remyelinating cell population in adult mammals. Dev. Neurosci. 11, 132-139 (1989).
6. Seilhean, D., Gansmuller, A., Baron-Van Evercooren, A., Gumpel, M. & Lachapelle, F. Myelination by transplanted human and mouse central nervous system tissue after long-term cryopreservation. Acta Neuropathol. 91, 82-88 (1996).
7. Mitome, M. et al. Towards the reconstruction of central nervous system white matter using neural precursor cells. Brain 124, 2147-2161 (2001).
8. Yandava, B., Billinghurst, L. & Snyder, E. Global cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain. Proc. Natl. Acad. Sci. USA 96, 7029-7034 (1999).
9. O'Leary, M.T. & Blakemore, W.F. Oligodendrocyte precursors survive poorly and do not migrate following transplantation into the normal adult central nervous system. J. Neurosci. Res. 48, 159-167 (1997).
10. Learish, R.D., Brustle, O., Zhang, S.C. & Duncan, I.D. Intraventricular transplantation of oligodendrocyte progenitors into a fetal myelin mutant results in widespread formation of myelin. Ann. Neurol. 46, 716-722 (1999).
11. Zhang, S.C., Ge, B. & Duncan, I.D. Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity. Proc. Natl. Acad. Sci. USA 96, 4089-4094 (1999).
12. Nunes, M.C. et al. Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain. Nat. Med. 9, 439-447 (2003).
13. Roy, N.S. et al. Identification, isolation, and promoter-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter. J. Neurosci. 19, 9986-9995 (1999).
14. Eisenbarth, G.S., Walsh, F.S. & Nirenberg, M. Monoclonal antibody to a plasma membrane antigen of neurons. Proc. Natl. Acad. Sci. USA 76, 4913-4917 (1979).
15. Raff, M.C., Miller, R.H. & Noble, M. A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303, 390-396 (1983).
16. Rao, M. & Mayer-Proschel, M. Glial-restricted precursors are derived from multipotential neuroepithelial stem cells. Dev. Biol. 188, 48-63 (1997).
17. Piper, D. et al. Identification and characterization of neuronal precursors and their progeny from human fetal tissue. J. Neurosci. Res. 66, 356-368 (2001).
18. Ridge, J., Fuchs, E. & Matzinger, P. Neonatal tolerance revisited: turning on newborn T cells with dendritic cells. Science 271, 1723-1726 (1996).
19. Roser, B. Cellular mechanisms in neonatal and adult tolerance. Immunol. Rev. 107, 179-202 (1989).
20. Windrem, M. et al. Progenitor cells derived from the adult human subcortical white matter disperse and differentiate as oligodendrocytes within demyelinated regions of the rat brain. J. Neurosci. Res. 69, 966-975 (2002).
21. Keyoung, H.M. et al. Specific identification, selection and extraction of neural stem cells from the fetal human brain. Nat. Biotechnol. 19, 843-850 (2001).
22. Louissaint, A., Rao, S., Leventhal, C. & Goldman, S.A. Coordinated interaction of angiogenesis and neurogenesis in the adult songbird brain. Neuron 34, 945-960 (2002).
23. Benraiss, A., Chmielnicki, E., Lerner, K., Roh, D. & Goldman, S.A. Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain. J. Neurosci. 21, 6718-6731 (2001).
24. Goldman, S.A., Lemmon, V. & Chin, S.S. Migration of newly generated neurons upon ependymally derived radial guide cells in explant cultures of the adult songbird forebrain. Glia 8, 150-160 (1993).
25. Franklin, R.J. & Blakemore, W.F. Transplanting oligodendrocyte progenitors into the adult CNS. J. Anat. 190, 23-33 (1997).